Korean Journal of Clinical Pharmacy (한국임상약학회지)

Korean College Of Clinical Pharmacy (한국임상약학회)
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A Case Study using Transferability Diagnosis Tools Between Countries for Economic Evaluations of Rheumatoid Arthritis Drugs

경제성평가의 국가간 적용가능성 진단도구를 이용한 류마티스관절염 치료제 사례 연구

  • Ku, Hye-Min (Graduate School of Clinical Pharmacy, Sookmyung Wuomen's University) ;
  • Kwon, Jeong-Mi (Graduate School of Clinical Pharmacy, Sookmyung Wuomen's University) ;
  • Park, Se-Young (Graduate School of Clinical Pharmacy, Sookmyung Wuomen's University) ;
  • Kang, Suk-Hyun (Graduate School of Clinical Pharmacy, Sookmyung Wuomen's University) ;
  • Lee, Eui-Kyung (Graduate School of Clinical Pharmacy, Sookmyung Wuomen's University)
  • 구혜민 (숙명여자대학교 임상약학대학원) ;
  • 권정미 (숙명여자대학교 임상약학대학원) ;
  • 박세영 (숙명여자대학교 임상약학대학원) ;
  • 강숙현 (숙명여자대학교 임상약학대학원) ;
  • 이의경 (숙명여자대학교 임상약학대학원)
  • Received : 2009.08.08
  • Accepted : 2009.09.30
  • Published : 2009.12.31
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Abstract

Objectives: With more and more health economic evaluations being performed in many countries, the question of whether the results from the foreign studies can be transferred to other country is becoming important. The objective of this study was to conduct a case study using three transferability diagnosis tools for economic evaluation on rheumatoid arthritis. Methods: Three diagnosis tools were used to assess transferability: Welte's tool, Boulenger's and Urdahl's. Five researchers who have experience on economic evaluation made consensus on the evaluation through the semi-delphi method. Results: With Welte's tool, absolute and relative prices in healthcare, practice variation, health-status preference, productivity and work-loss time were evaluated as biased. The transferability information score by Boulenger's was 85.9%, which means qood quality reporting. In case of Urdahl's, research questions were well defined and reporting was transparent and explicitly stated. However, both the relevance of data inputs to Korea and robustness of model were relatively low. In conclusion the UK study on rheumatoid arthritis could be partially transferable to Korea, and will need modeling-based adjustments.

Keywords

References

  1. Drummond MF, Bloom BS, Carrin G, et al.: Issues in the cross-national assessment of health technology. Int J Technol Assess Health Care. 8, 671 (1992).
  2. Francis Pang.: Design, Analysis and Presentation of Multinational Economic Studies: The Need for Guidance. Pharmacoeconomics. 20, 75 (2002). https://doi.org/10.2165/00019053-200220020-00001
  3. Robert Welte, Talitha Feenstra, Hans Jager and Reiner Leidl.: A Decision Chart for Assessing and Improving the Transferability of Economic Evaluation Results Between Countries. Pharmacoeconomics 22, 857 (2004). https://doi.org/10.2165/00019053-200422130-00004
  4. Stephanie Boulenger, John Nixon, Michael Drummond, Philippe Ulmann, Stephen Rice, Gerardde Pouvourville.: Can economic evaluations be made more transferable? Eur J Health Econ. 6, 334 (2005). https://doi.org/10.1007/s10198-005-0322-1
  5. John Nixon, Stephen Rice, Michael Drummond, Stephanie Boulenger, Philippe Ulmann, Gerard de Pouvourville.: Guidelines for completing the EURONHEED transferability information checklist. Eur J Health Econ. 10, 157 (2009). https://doi.org/10.1007/s10198-008-0115-4
  6. Hege Urdahl, Andrea Manca, and Mark J Sculpher.: Assessing Generalisability in Model-Based Economic Evaluation Studies: A Structured Review in Osteoporosis Pharmacoeconomics. 24, 1181 (2006). https://doi.org/10.2165/00019053-200624120-00004
  7. New treatments in arthritis: the use of TNF-_ blockers in adults with rheumatoid arthritis. Report of a working party of the British Society for Rheumatology, 2 April 2001.
  8. Brennan, N. Bansback, A. Reynolds, P. Conway.: Modelling the cost-effectiveness of etanercept in adults with rheumatoid arthritis in the UK A. Rheumatology. 43, 62 (2004); https://doi.org/10.1093/rheumatology/keg451
  9. National Institute for Clinical Excellence. Guidance for manufacturers and sponsors: Technology appraisals process series No. 5. London. National Institute for Clinical Excellence. (2001).
  10. Saskia Knies, MPhil, Andre J. H. A. Ament, PhD, Silvia M. A. A. Evers, PhD, Johan L. Severens, PhD.: The Transferability of Economic Evaluations:Testing the Modelof Welte. Value in Health. 12, 730 (2009).he_ https://doi.org/10.1111/j.1524-4733.2009.00525.x
  11. Sculpher MJ, Pang FS, Manca A, Drummond MF, Golder S, Urdahl H, Davies LM, Eastwood A.: Generalisability in economic evaluation studies in healthcare: a review and case studies. Health Technol Assess. 49, 1 (2004) .