• Title/Summary/Keyword: Data interpretation, statistical

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Effect of Cash flow on the R&D investment of Pharmaceutical Companies - focused on KOSDAQ market (제약회사의 현금흐름이 연구개발투자에 미치는 영향 -코스닥시장을 중심으로)

  • Lee, Munjae;Choi, Mankyu
    • The Journal of the Korea Contents Association
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    • v.15 no.8
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    • pp.473-480
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    • 2015
  • The purpose of this study is to analyze the influence of the cash flow of pharmaceutical companies on R&D investment. 143 pharmaceutical companies listed in the KOSDAQ market from 2009 to 2013. Financial statements and comments in general and internal transactions were extracted from TS-2000 of the Korea Listed Company Association (KLCA), and data related to stock price was extracted from KISVALUE-III of NICE Information Service Co., Ltd. STATA 12.0 was used as the statistical package for panel analysis. The summary of the findings and the interpretation of the significance of this are as follows: First, the current ratio (internal finance) had a positive influence on R&D investment. Second, the debt ratio (external finance) had a negative influence on R&D investment. The pharmaceutical company prefers internal funds to external funds due to the asymmetry of information in the loan markets. In other words, this shows why internal finances have a significant influence on R&D investment at pharmaceutical companies.

The Relationship between R&D investment and Ownership Structure in KOSDAQ Pharmaceutical Firms (코스닥 제약기업의 연구개발투자와 소유구조 간의 관계)

  • Lee, Munjae;Choi, Mankyu
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.445-454
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    • 2015
  • The purpose of this study is to analyze the influence of the financial structure of pharmaceutical companies on R&D investment. 358 pharmaceutical firms listed in the KOSDAQ market from 2000 to 2012. Financial statements and comments in general and internal transactions were extracted from TS-2000 of the Korea Listed Company Association (KLCA), and data related to stock price was extracted from KISVALUE-III of NICE Information Service Co., Ltd. STATA 12.0 was used as the statistical package for panel analysis. The summary of the findings and the interpretation of the significance of this are as follows: First, the shareholding ratio of major shareholders and foreigners had a positive influence on R&D investment. Second, the ratio of outside directors had a negative influence on R&D investment. Third, the shareholding ratio of institutional investors did not have a significant influence on R&D investment.

The distribution characteristics of trace elements of fine ambient particulate in Korea

  • Lim, Jong-Myoung;Lee, Jin-Hong;Kim, Ki-Hyun
    • Analytical Science and Technology
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    • v.18 no.3
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    • pp.241-249
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    • 2005
  • In this study, instrumental neutron activation analysis was used to measure the concentrations of about 30 trace elements in airborne particulate (PM2.5) samples at urban area of Daejeon city located in the southwestern region of Korea. An inspection of the measurement data indicates that the distribution patterns of trace elements could clearly distinguish the elements with their concentrations ranging over five orders of magnitude. The mean values for Lu and Dy were found to be the lowest at values of 0.01 and $0.04ng/m^3$, while those for K and Fe showed the highest value of 671 and $653ng/m^3$, respectively. The results of correlation analysis showed that PM2.5 concentrations can exhibit much more enhanced correlations with the elements of earth crustal components. The results of factor analysis further indicated that there are no more than six factors with statistical significance, which may exert dominant roles in regulating the elemental concentration levels in the study area. Enrichment factor analysis supports explicit interpretation of results found by this factor analysis.

Hematological and biochemical analysis of Korean indigenous cattle according to the ages (한우의 연령에 따른 혈액 및 혈청 화학치 분석)

  • Cho, Hyun-Ung;Ko, Won-Seuk;Son, Hyong-Won;Lee, Mi-Jin;Song, Hee-Jong;Park, Jin-Ho
    • Korean Journal of Veterinary Service
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    • v.31 no.1
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    • pp.137-147
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    • 2008
  • Investigations for hematologic and biochemical values and the differential count of WBC for Korean indigenous cattle (KIC)is rarely performed. Therefore, when the index of complete blood counts (CBC) and biochemical analysis of KIC was requested, it had many difficulties to make the results for blood condition since the standard hematologic and biochemical values of KIC are lacking. In the present study, we have investigated the hematologic and biochemical values and the differential count of WBC for blood of total 252 KIC and 17 striped cattle (SC) as a control. As a result, the mean values of RBC and platelet of KIC were significantly decreased by age (P<0.05). The mean values of RBC, HCT, MCV and MCHC between KIC and SC of the same age (2 - 3 years) showed the statistical significance (P<0.05). Also, in the WBC of KIC, the mean values were decreased according to the age from $12.8{\times}10^3/{\mu}l$ under 1 year to $8.5{\times}10^3/{\mu}l$ over 5 years. In the differential count of WBC of KIC, it showed generally the rates of 45% lymphocyte and 35% segmented neutrophil. In the biochemical analysis, the mean values of BUN and globulin were significantly increased according to the age (P<0.05). Additionally, in comparative analysis between pregnant and non-pregnant group of KIC, the mean values of Hg and HCT in pregnant group were significantly decreased (P<0.05). In conclusion, data obtained from this study may be valuable as a standard for interpretation of the results in hematologic and biochemical analysis of KIC.

Characteristics of Natural Prints Design in Fashion Collections - Paris, Milan & New York from 2011 SS to 2012 SS - (패션 컬렉션에 나타난 자연문양디자인의 특성 - 2011 S/S ~2012 S/S 파리, 밀란, 뉴욕 컬렉션을 중심으로 -)

  • Kwon, Hae-Sook
    • Journal of the Korea Fashion and Costume Design Association
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    • v.15 no.1
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    • pp.91-109
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    • 2013
  • The main objective of this research was to understand the latest trends of natural print design through the quantitative & qualitative analysis of fashion appeared in contemporary female collections. The research criteria was defined as 3 seasons from 2011 S/S to 2012 S/S. Data collection of 726 was done through review of 'pr$\hat{e}$t-$\grave{a}$-porter Collections' of three major fashion cities; Paris, Milan and NY. Statistical analysis of frequency with chi-square test was conducted. Also qualitative interpretation of natural print design' characteristics was completed. The main findings were as follows.; The average occurrence rate of natural print design from 2011SS to 2012 SS in three collections were 6.4% in Milan 6.4%, 5.5% in Paris and 6.8% in N.Y. The five source types of natural prints in contemporary women's fashion collections were identified and the order of their appearance were as follows: flowers, plants, animals, insects & marine organisms and compound one. The plant prints were expressed by stylized or realistic touch. Flower patterns showed more variables than plants, however, there were no big difference in their image and major characteristics. The animal prints demonstrated two aspects. First one used typical animal print of fur or skin, but the other one draw the animal figure like paintings. The compound source type presented the most interesting and fresh pattern design ideas. In the insects & marine organisms, mainly butterfly and seashell & starfish, etc. appeared as real shapes or sometimes were stylized.

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Filtered Coupling Measures for Variable Selection in Sparse Vector Autoregressive Modeling (필터링된 잔차를 이용한 희박벡터자기회귀모형에서의 변수 선택 측도)

  • Lee, Seungkyu;Baek, Changryong
    • The Korean Journal of Applied Statistics
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    • v.28 no.5
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    • pp.871-883
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    • 2015
  • Vector autoregressive (VAR) models in high dimension suffer from noisy estimates, unstable predictions and hard interpretation. Consequently, the sparse vector autoregressive (sVAR) model, which forces many small coefficients in VAR to exactly zero, has been suggested and proven effective for the modeling of high dimensional time series data. This paper studies coupling measures to select non-zero coefficients in sVAR. The basic idea based on the simulation study reveals that removing the effect of other variables greatly improves the performance of coupling measures. sVAR model coefficients are asymmetric; therefore, asymmetric coupling measures such as Granger causality improve computational costs. We propose two asymmetric coupling measures, filtered-cross-correlation and filtered-Granger-causality, based on the filtered residuals series. Our proposed coupling measures are proven adequate for heavy-tailed and high order sVAR models in the simulation study.

The Characteristics of Separation Color Coordination In Current Women's Fashion collections of Paris, Milan, N.Y, London from 2004 SS - 2008 A W - centering on the types of color scheme, color harmony, separation color - (최신 여성 패션에 나타난 세퍼레이션 색채 코디네이션의 특성)

  • Kwon, Hae-Sook
    • Journal of Fashion Business
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    • v.12 no.5
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    • pp.94-110
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    • 2008
  • The main objective of this research was to understand the characteristics of separation color coordination of contemporary female fashion through the analysis of 'pre-a-porter Collections' of four collections (i. e. cities) - Paris, Milan, New York, London - from the periods of 2004 S/S to 2008/9 A/W. The data collection of 265 was done by reviewing 'pre-a-porter Collections' magazine and total 265 observations were made. Statistical analysis of frequency and also qualitative interpretation of separation color coordination characteristics were completed. The main findings were; (1) In separation color coordination of contemporary women's fashion collections, there were three main types of color scheme which were classified into seven detailed categories of color combination. First was the achromatic color & one chromatic separation color scheme which was classified into four categories of - black & white, black & grey, white & grey, and grey & grey - color combination. Second was the chromatic colors & one achromatic separation color scheme which classified into two categories of achromatic & chromatic color & one achromatic separation color combination, and chromatic colors & one achromatic separation color combination. Third was chromatic colors and one chromatic separation color combination. (2) The achromatic colors and one chromatic separation color scheme showed two phases of reinforcing the strong and modern image, or softening the hard and dull image of achromatic color combination. In color schemes which used more than two chromatic colors, the separation color frequently converted the tedious and monotonous fashion image, which caused by identical or similarity in color or tone harmony, into more attractive and interesting. (3) In conclusion, through the various use and coordination of various color schemes, color harmony and separation colors, the separation color coordination in contemporary female fashion has been suggested the effective way of color combination which can lead the visual pleasure and the vitality along with the unity and the harmony. This characteristics can create various images and visual diversity for fashion. The types and the use of color scheme and separation color showed different trends in four collections.

The Study on the Diagnostic Value of Salivary Gland Scintigraphy in Patients with Xerostomia (구강건조증 환자의 타액선 스캔의 진단학적 가치에 관한 연구)

  • Chung, Sung-Chang;Lee, Sung-Woo;Kim, Young-Ku;Kho, Hong-Seop;Yum, Kwang-Won
    • Journal of Oral Medicine and Pain
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    • v.25 no.2
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    • pp.145-151
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    • 2000
  • The present study was performed to investigate the relationship between the salivary flow rate and the interpretation results of salivary scan in the patients with dry mouth. Twenty-five patients with dry mouth who visited the Dept. of Oral Medicine & Oral Diagnosis, Seoul National University Dental Hospital, were included. The unstimulated whole salivary flow rate was determined by the spitting method and the stimulated whole salivary flow rate was measured with gum-base chewing. Salivary scan was performed after the infusion of $^{99m}technetium$ pertechnetate(Tc) and interpreted. The obtained results were as follows: 1. The unstimulated and stimulated whole salivary flow rate were significantly decreased compared to normal value, which reflected the extensive destruction of salivary gland function in the patients with dry mouth. 2. The unstimulated and stimulated whole salivary flow rate were decreased in the group with decreased function in salivary scan compared with the group with normal function in salivary scan. However, there was no statistical significance between groups. 3. The difference between the stimulated and unstimulated whole salivary flow rates was greater in the group with normal function in salivary scan compared with the group with decreased function in salivary scan. 4. There was significant positive correlation between the stimulated and unstimulated whole salivary flow rates. The level of correlation was higher in the group with decreased function in salivary scan than the group with normal function in salivary scan. Collectively, these data suggested that salivary scan had the limited value. The comprehensive evaluation including history taking, clinical examination, clinical laboratory as well as the measurement of salivary flow rate are need for patients with dry mouth.

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A Study on the Scope and Expansion of Arts Management - Centering on International Art Markets - (미술경영의 범위와 확장에 관한 연구 - 국제미술시장을 중심으로 -)

  • Cheong, In Seo
    • International Area Studies Review
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    • v.13 no.2
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    • pp.712-739
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    • 2009
  • This study organized various perspectives on the scope of arts management in terms of business management based on bibliographical speculations and statistical data. Management of arts such as performance art involves organizational management, human resources management, marketing and financial management. However arts management needs a new perspective in terms of access to specific academic area of arts while it can be approached in a derivative perspective of management theories. For arts include professional areas that need aesthetic perspective and interpretation of aesthetic history. As art market were opened where active international exchanges have been made over the past ten years, a new strategic approach in management is needed for major international arts markets such as the U.S.A., Europe and China. Such international arts markets involve international auctions markets, international Biennale, international art fair and overseas advance of galleries. First, we need strategic approaches such as nurturing star artists. Second, large-scale exhibition planning of artistic works from world-famous museums or art museums should be developed.

Improvement of the Discrimination Capacity through the Expansion of Y Chromosomal STR Markers

  • Dong Gyu Lee;So Eun Lee;Ji Hwan Park;Si-Keun Lim;Ju Yeon Jung
    • Biomedical Science Letters
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    • v.29 no.4
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    • pp.302-313
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    • 2023
  • Y chromosomal short tandem repeat (Y-STR) markers have been developed continuously to complement forensic DNA analyses and population genetic studies. Initially, we collected data from previously reported Korean population Y-STR haplotype studies on 1133 individuals. We then conducted a marker expansion analysis using a dataset from the Y-STR Haplotype Reference Database (YHRD), covering up to 29 Y-STRs, referred to as Ymax. Additionally, we examined the impact of rapidly mutating (RM) Y-STRs included in this expanded marker set on the discrimination capacity. We observed that marker expansions both with (0.9896), and without (0.9510), RM Y-STR improved the discrimination capacity. Subsequently, we focused on 16 individuals belonging to seven distinct groups sharing identical haplotypes. These particular haplotypes had been previously identified among 476 unrelated males using 23 Y-STR markers from the PowerPlex® Y23 System. We expanded the marker panel up to Ymax to explore how discrimination improved with an expansion of Y-STR markers for these 16 individuals. Among the expanded markers, DYS627, which had high discriminatory power, had a high mutation rate (1.10 × 10-2) and high gene diversity (0.83). In contrast, DYF387S1 displayed high gene diversity (0.95) but a relatively low mutation rate (2.80 × 10-3). We propose that these findings will be valuable in the selection of suitable Y-STR markers, depending on the objectives of forensic analyses. Additionally, the presence of frequently observed Y-haplotypes in Korean population will facilitate statistical interpretation in Y-STR DNA profiling.