• Nuclear Engineering and Technology
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• v.22 no.2
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• pp.116-127
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• 1990

The fission gas release model used In the SPEAR-BETA fuel performance code was modified by use of effective thermal conductivity for cracked fuel and by laking Into account axial fission-gas mixing between the fuel-clad gap and the plenum. With use of this modified model the fission gas release was analyzed under various power ramping conditions of P$_{max}$ and $\Delta$.fP. Effective fuel thermal conductivity that accounts for the effect of fuel tracking was used in calculation of the fuel temperature distribution and the Internal gas pressure under power ramping conditions. Mixing and dilution effects due to axial gas flow were also considered in computing the width and the thermal conductivity of the gap. The effect of axial gas flow w3s solved by the Crank-Nicholson method. The finite difference method was used to save running time in the calculation. The present modified fission-gas release model was validated by comparing its predicted results with experimental data from various lamping tests In the literature and calculated results with use of the models used In the SPEAR-BETA and FEMAXI-IV codes. Results obtained with use of the present modified model showed better agreement with experimental data reported in the literature than those results with use of the latter codes. The fuel centerline temperature calculated with introduction of effective thermal conductivity for centerline temperature calculated with Introduction of effective thermal conductivity for cracked fuel was 200 higher fission gas release predicted with use of the modified model was nearly 6% larger on the average than that calculated by use of the unmodified model used in the SPEAR-BETA code.e SPEAR-BETA code.e.

• Journal of Information Technology Applications and Management
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• v.11 no.4
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• pp.87-94
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• 2004

The software reliability growth model(SRGM) has been developed in order to estimate such reliability measures as remaining fault number, failure rate and reliability for the developing stage software. Almost of them assumed that the faults detected during testing were evetually removed. Namely, they have studied SRGM based on the assumption that the faults detected during testing were perfectly removed. The fault removing efficiency. however. IS imperfect and it is widely known as so in general. It is very difficult to remove detected fault perfectly because the fault detecting is not easy and new error may be introduced during debugging and correcting. Therefore, the fault detecting efficiency may influence the SRGM or cost of developing software. It is a very useful measure for the developing software. much helpful for the developer to evaluate the debugging efficiency, and, moreover, help to additional workloads necessary. Therefore. it is very important to evaluate the effect of imperfect dubugging in point of SRGM and cost. and may influence the optimal release time and operational budget. I extent and study the generally used reliability and cost models to the imperfect debugging range in this paper.

• KSBB Journal
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• v.26 no.3
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• pp.217-222
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• 2011

Itraconazole is a triazole antifungal agent to inhibit most fungal pathogens. To improve the oral absorption and dissolution of poorly water-soluble itraconazole, microsponge system composed of $Eudragit^{(R)}$ E100 and polyvinyl alcohol(PVA) formulated by quasi-emulsion solvent diffusion method, and its physicochemical properties and pharmacokinetic parameters of itraconazole were studied. The microsponge of itraconazole were discrete free flowing micro sized particles with perforated orange peel like morphology as visualized by scanning electron microscope (SEM). Results showed that the drug loading efficiency, production yield, and particle size of itraconazole microsponge were affected by drug to polymer ratio, the volume of internal phase containing methylene chloride, stirring rate and the concentration of PVA used. Also, the results showed that the dissolution rate of itraconazole from the microsponges was affected by drug to polymer ratio. In other words, the release rate of itraconazole from microsponges was increased from at least 27.43% to 64.72% after 2 h. The kinetics of dissolution mechanism showed that the dissolution data followed Korsmeyer-Peppas model. Therefore, these results suggest that microsponge system can be useful for the oral delivery of itraconazole by manipulating the release profile.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.1-8
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• 2010

Purpose : The purpose of this study was to evaluate the Influence of Infra red(IR) and myofascial release(MRF) on the range of motion and pain in persons with neck pain. Methods : 24 subjects with neck pain participated in the experiment. All subject randomly assigned to the IR group and MFR group. Both groups receive 10minutes, 3 times per week during 3 weeks period. laser exercise(LEX) used to measure range of motion of neck and visual analog scale(VAS) used to measure pain. All measurements of each subject were measured at pre-treatment and post-treatment. Results : 1. The neck flexion, extension, right-sidebending, left-rotation, right-rotation range of motion of MFR group was significantly increased.(P<0.05). 2. The neck left-sidebending, left-rotation, right-rotation range of motion of IR group was significantly increased.(P<0.05). 3. As to compare two group, MFR group increases ROM more than IR group. Conclusion : These data suggests that MFR is more beneficial than IR.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2004.05a
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• pp.620-623
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• 2004

Conventionally injection molds & dies are manufactured through an order-oriented manner. This brings unexpected orders into the shop floor such as hot order, re-work, and new types of mold & dies. Thus, there needs appropriate resource assignment plans considering the available times of machines and workers. Further, a scheduling system is required that can create work schedules periodically or by customers' requests. Yet, in small & medium sized mold & die makers, production schedules usually depend on the shop floor workers' experience and their manual preparation. Hence, developed in this study is a scheduling management system (SMS) based on order release and review (ORR) in small and medium sized mold & die companies. The proposed SMS considers delivery dates as well as flexible work schedules, so as to meet frequent changes of customers' order. The system can provide effective resource assigning and work scheduling plans, securing standard data associated with shop floors. Furthermore, the system pursues economical schedules for companies' needs, equipped with an available to promise (ATP) function that can effectively accommodate the changes of production plans.

• Journal of Pharmaceutical Investigation
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• v.41 no.2
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• pp.111-115
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• 2011

pH-sensitive cross-linked polymeric micelles were synthesized by using block ionomer complexes of poly(ethylene oxide)-b-poly(methacrylic acid) (PEO-b-PMA) with calcium ions as micellar templates. An anticancer drug, doxorubicin (DOX) was conjugated on the cross-linked ionic cores of micelles via acid-labile hydrozone bonds. The resulting DOX-conjugated, pH-sensitive micelles are stable at physiological conditions, whereas the release of DOX was significantly increased at the acidic pH. Such micelles were internalized to lysosomes, and acidic pH in lysosomes triggers the release of DOX upon internalization in MCF-7 breast cancer cells. The released DOX entered the cell nucleus and eventually killed cancer cells. Therefore, these data demonstrate that the pH-sensitive micelles could be a promising nanocarrier for delivery of anticancer drug, DOX.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.3
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• pp.416-423
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• 2003

During the last ten years, the need has been increased for reducing maintenance cost for aged equipments and ensuring safety, efficiency and profitability of petrochemical and refinery plants. RBI (Risk Based Inspection) methodology is one of the most promising technologies satisfying the need in the field of integrity management. In this study, a user-friendly software, realRBl for RBI based on the API 581 code was developed. This software has modules for evaluating qualitative and semi-quantitative risk level, analyzing quantitative risks using the potential consequences of a failure of the pressure boundary, and assessing the likelihood of failure. A quantitative analysis was performed for 16 columns in a domestic NCC (Naphtha Cracking Center) plant whose operating time reaches about 12 years. Each column was considered as two equipment parts by dividing into top and bottom. Generic column failure frequencies were adjusted based on likelihood data. After determining release rate, release duration and release mass for each failure scenario, flammable/explosive and toxic consequences were assessed. Current risks for 32 equipment parts were evaluated and risk based prioritization were determined as a final result.

• Fire Science and Engineering
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• v.25 no.5
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• pp.47-53
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• 2011

Fire load in buildings greatly contribute to the time and scale of fire according to the type and quantity of the fire load. Because bookstores have a large quantity of fire load compared with other buildings which may lead to large scale fires, however, their heat release characteristics have been hardly investigated. In this study, to obtain the data applicable for the performance-based fire safety design of bookstores, the specimens representing stacked fire loads were heated in a furnace in compliance with the standard heating curve of ISO834-1:1999 to investigate their heat release characteristics. From the experiment result, the combustion velocity and heat release rate required for performancebased fire safety designs are obtained.

• Proceedings of the Korean Nuclear Society Conference
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• 1996.05b
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• pp.637-642
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• 1996

This paper presents the analysis results for the core degradation processes and the fission product release of the PHEBUS FPT0 experiment using MELCOR1.8.3. The objective of this study is to assess models associated with the core damage and fission product behavior in MELCOR. The calculation results were much improved through sensitivity studies. Thermal/hydraulic behavior in the core and the circuit was well predicted under the intact core geometry. In non-eutectic model case. the UO$_2$ dissolution model in the MELCOR always showed such a tendency that the resulting dissolved UO$_2$ mass was small at the highly oxidized condition due to the model logic. Total H$_2$ generation mass was underpredicted because the stiffner was not modeled and the liner in the shroud was not allowed to be oxidized in MELCOR. Some difficulties were found in modeling the activation product were solved by manipulating the RN input associated with the initial fission product inventory. These problem were occurred because there are no control rod model in MELCOR. Generally the fission product release ratio showed a similar trend compared with the measured data except the activation product. which have no model to simulate in MELCOR.

• Fire Science and Engineering
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• v.22 no.1
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• pp.37-44
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• 2008

The reduced scale fire test provides basic data but it is not enough to analysis real fire problem directly because there is no exact analogy theory between a real fire and the reduced scale model. Therefore, we have developed the 10 MW large scale calorimeter in order to real scale fire test. This advanced large scale calorimeter used for physical properties such as a heat release rate, based upon consumption of $O_2$ method. Using the heptane pool fire, we carried out the calibration in order to evaluation for heat release rate. It is approve that this facility has the reliability and it is capable of applying to the advance fire research in the future.