• Journal of Biomedical Engineering Research
• /
• v.27 no.3
• /
• pp.94-100
• /
• 2006

The effectiveness of the treatment of intracranial aneurysms with endovascular coiling depends on coil packing density, the location of aneurysm, its neck dimensions with respect to the aneurysm dome, and its size with respect to the surrounding tissue. Clinical data also suggests that the aneurysm neck size is the main predictor of aneurysm recanalization. In this study, the force impinging on the aneurysm neck in an idealized aneurysm was calculated by using a three dimensional finite volume method for the non-Newtonian incompressible laminar flow. To quantify the effect of neck size on the impingement force, calculations were performed for aneurysm neck diameters (Da) varying from 10% to 100% of the parent artery diameter (Dp). Also, maximum impingement forces were represented by a function of the ratio of the aneurysm neck to the diameter of the parent vessel. The results show that the hemodynamic forces exerted on the coil mass at the aneurysm neck due to the pulsatile blood flow are larger for wide necked aneurysms.

• Proceedings of the Korea Society for Simulation Conference
• /
• 2000.11a
• /
• pp.28-33
• /
• 2000

This article describes the application of discrete event simulation in a process industry (coffee manufacturing) as a daily production-scheduling tool. A large number of end products (around 300), sporadic demand, and limited shelf life of coffee (90 days) make it difficult to generate feasible production schedules manually. To solve this problem an integrated system was developed incorporating discrete event simulation methodology into scheduling process. The integrated system is comprised of two components: a scheduling program and a simulation model. The scheduling program is used to generate daily schedules for roasting, grinding, and packing coffee. The simulation model uses the generated schedules to simulate the production of coffee and regenerates a modified production schedule. In this paper, each of the components will be described in detail, evaluated in terms of performance factors, and validated with a set of real production data. Although this article focuses on a specific system, we will share our experiences and intuitions gained and encourage other process industries to develop simulation-based scheduling tools.

• YAKHAK HOEJI
• /
• v.18 no.4
• /
• pp.236-242
• /
• 1974

Extrusion-spheronization processing combination was used to produce spherical granules with experimental formulations which contain microcrystalline cellulose as a diluent. The produced granules were compared on the basis of the following physical properties ; (a) bulk density, (e) porosity, (f) friabillity and (g) dissolution rate. With the specific experimental formulations used in this study, the increased plate rotational speeds of Marumerizer (400-1200rpm) produced continually more spherical material and also the obtained data indicated that the particle size distribution and dissolution rate depend upon the amount of microcrystalline cellulose used. As a result, the spherical granule preparation with microcrystalline cellulose has good properties in flow rate, packing propertyu and friability and offers a suitable method of granule preparation in pharmaceutical industry.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2004.11a
• /
• pp.153-156
• /
• 2004

Most concrete is recently made of an aggregate which is properly absorbed. and carried in it in order to do capability at every fields. We have been close to demand new capability of high flowing and enduring for specific concretes. That is difficult to cope with claiming the efficiency on deterioration from lack of a high quality aggregate. Therefore. For solving the problems we apply to a packing method for using dried materials. That is to say it is a kind of making into an instant. In this study. There is a purpose to present fundamental data. comparing and analyzing a phenomenon about aggregate's absorption following the rate of adding water. for using existing materials.

• Industrial Engineering and Management Systems
• /
• v.3 no.1
• /
• pp.22-37
• /
• 2004

An integrated heuristic approach based on genetic algorithms (GAs) is proposed for solving the container selection and loading problems. The GA for container selection solves a two-dimensional knapsack problem, determining a set of containers to minimize the transportation or shipment cost. The GA for container loading solves for the weighted coefficients in the evaluation functions that are applied in selecting loading positions and boxes to be loaded, so that the volume utilization is maximized. Several loading constraints such as box orientation, stack priority, stack stability, and container stability are also incorporated into the algorithm. In general, our computational results based on randomly generated data and problems from the literature suggest that the proposed heuristic provides a good solution in a reasonable amount of computational time.

• Journal of the Korea Institute of Building Construction
• /
• v.3 no.4
• /
• pp.119-122
• /
• 2003

Most concrete is recently made of an aggregate which is properly absorbed, and carried in it in order to do capability at every fields. We have been close to demand new capability of high flowing and enduring for specific concretes. That is difficult to cope with claiming the efficiency on deterioration from lack of a high quality aggregate Therefore, For solving the problems we apply to a packing method for using dried materials. That is to say it is a kind of making into an instant. In this study, There is a purpose to present fundamental data, comparing and analyzing a phenomenon about aggregate's absorption following the rate of adding water, for using existing materials.

• Bulletin of the Korean Chemical Society
• /
• v.6 no.1
• /
• pp.7-11
• /
• 1985

The crystal structure of phlorizin, a ${\beta}$ -D-glucopyranoside of a flavonoid dihydrochalcone phloretin, has been determined by single crystal diffraction methods using diffractometer data obtained by the ${\omega}-2{\theta}$ scan technique with Cu $K{\alpha}$ radiation from a crystal with space group symmetry $P2_12_12_1$ and unit cell parameters a = 4.9094 (2), b = 19.109 (1), c = 23.275 (4) $\AA$. The structure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.047 for the 1697 observed reflections. The dihydrochalcone moiety is flat and fully extended. The glucose ring has the $^4C_1$ chair conformation and the conformation of the primary alcohol group is gauche-gauche. The crystal packing is dominated by an extensive hydrogen bonding pattern. There are one strong and two weak intramolecular hydrogen bonds in the phlorizin molecule.

• Bulletin of the Korean Chemical Society
• /
• v.4 no.3
• /
• pp.123-127
• /
• 1983

The crystal structure of metoclopramide, $C_14H_22ClN_3O_2$, has been determined by X-ray diffraction techniques using diffractometer data obtained by the ${\omega}-2{\theta}$ scan technique with Mo $K\alpha$ radiation from a crystal with space group symmetry $P{\overline{1}}$ and unit cell parameters a = 7.500(1), b = 8.707(2), c = 13.292(2) ${\AA}$; ${\alpha}$ = 101.70(2), ${\beta}$ = 81.20(2), and ${\gamma}$ = $114.90(l)^{\circ}$. The sructure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.055 for the 1524 observed reflections. The bent overall-conformation of the molecule seems to be determined mainly by the bifurcated intramolecular hydrogen bond from the amide nitrogen atom to the methoxy oxygen and the amine nitrogen atoms. The crystal packing consists of the hydrogen bonds, ${\pi}-{\pi}$ interaction and hydrophobic interaction.

• Bulletin of the Korean Chemical Society
• /
• v.6 no.4
• /
• pp.222-224
• /
• 1985

The crystal structure of sulindac, $C_{20}H_{17}Fo_3S$, one of the nonsteroid antiinflammatory agents, has been determined by the X-ray diffraction techniques using diffractometer data obtained by the $\varpi-2{\theta}$ scan technique with Cu $$K_{\alpha}$$ radiation from a crystal with space group symmetry Pbca and unit cell parameters a = 8.166(1), b = 18.291(8), c = 23.245(10) ${\AA}.$ The structure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.11 for the 1153 observed reflections. The carboxyl group is nearly perpendicular to the indenyl ring as observed in indomethacin. The dihedral angle between the indenyl and phenyl rings is $35^{\circ}while$ the corresponding angle in indomethacin is $67^{\circ}.$ Crystal packing consists of a hydrogen bond and partial ring stacking between the indenyl rings.

• Journal of Korea Multimedia Society
• /
• v.12 no.4
• /
• pp.608-615
• /
• 2009

As RFID tag prices have rapidly been declining because of the advance of RFID technology, each tag is attached to an individual item, not a packing box only, for managing the item much more precisely. However, some mechanisms are essential to handle a very large amount of tag data quickly because readers and middlewares processing RFID data have limited hardware resources. In this paper, we design and implement a new mobile agent-based distributed software tools to satisfy this requirement efficiently. These tools provide a convenient environment enabling required data to be pre-processed repeatedly in transit by transferring a mobile agent including its specified data collection policy to numerous mobile readers. This behavior can significantly reduce the elapsed time required for processing huge volumes of tag data at the readers and middlewares with their very high recognition rates compared with the existing one to process the data by fixed readers after having arrived at the destination