• Survey Research
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• v.10 no.3
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• pp.1-19
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• 2009

This study investigates the utilities of spatial analysis in the context of survey research using Geographical Information System(GIS) and Geographically Weighted Regression (GWR) which take account of spatial heterogeneity. Many social phenomena involve spatial dimension, and with the development of GIS, GPS receiver, and online location-based services, spatial information can be collected and utilized more easily, and thus application of spatial analysis in the survey research is getting easier. The traditional OLS regression models which assume independence of observations and homoscedasticity of errors cannot handle spatial dependence problem. GWR is a spatial analysis technique which utilizes spatial information as well as attribute information, and estimated using geographically weighted function under the assumption that spatially close cases are more related than distant cases. Residential survey data from a Primary Autonomous District are used to estimate a model of public service satisfaction. The findings show that GWR handles the problem of spatial auto-correlation and increases goodness-of-fit of model. Visualization of spatial variance of effects of the independent variables using GIS allows us to investigate effects and relationships of those variables more closely and extensively. Furthermore, GIS and GWR analyses provide us a more effective way of identifying locations where the effect of variable is exceptionally low or high, and thus finding policy implications for social development.

• KDI Journal of Economic Policy
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• v.36 no.1
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• pp.1-42
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• 2014

This study analyzes how heterogeneous across firms' productivity level the effects of foreign direct investment (FDI) on the productivity of firms in a host country are. The study uses firm level data over 2000~2009 in South Korea and takes a quantile regression approach to estimate FDI's heterogeneous effects on the invested firm ('direct effects') and other domestic firms in the industry to which the invested firm belongs ('intra-industry spillover effects'). Major empirical results are as follows. In manufacturing sector, FDI has positive and statistically significant direct effects on the invested firm. In addition, the higher the quantiles of firms' productivity level are, the larger the positive productivity effects are. FDI also has positive and statistically significant intra-industry spillover effects on domestic firms in low quantiles of productivity while it has negative and statistically significant or insignificant spillover effects on those in high productivity quantiles. In service sector, on the other hand, Sufficient evidence is not found that FDI has statistically significant direct effects or intra-industry spillover effects. Taken together, the study suggests that FDI has heterogeneous effects on the productivity of firms in host country, depending on the firms' productivity level and sector.

• Journal of Bio-Environment Control
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• v.15 no.4
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• pp.289-295
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• 2006

A computational fluid dynamics (CFD) numerical model has been developed to effectively study the ventilation efficiency of multi-span greenhouses with internal crops. As the first step of the study, the internal plants of the CFD model had to be designed as a porous media because of the complexity of its physical shapes. In this paper, the results of the wind tunnel tests were introduced to find the aerodynamic resistance of the plant canopy. The Seogun tomato was used for this study which made significant effects on thermal and mass exchanges with the adjacent air as well as internal airflow resistance. With the main factors of wind speed, static pressure, and density of plant canopy, the aerodynamic resistance factor was statically found. It was finally found to be 0.26 which will be used later as an input data of the CFD model. Moreover, the experimental procedure of how to find the aerodynamic resistance of various plants using, wind tunnel was established through this study.

• Journal of the Korean Geographical Society
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• v.49 no.6
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• pp.917-934
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• 2014

Geographically weighted regression(GWR) model has been widely used to estimate spatially heterogeneous real estate prices. The GWR model, however, has some limitations of the selection of different price determinants over space and the restricted number of observations for local estimation. Alternatively, the geographically weighted LASSO(GWL) model has been recently introduced and received a growing interest. In this paper, we attempt to explore various local price determinants for the real estate by utilizing the GWL and its applicability to forecasting the real estate price. To do this, we developed the three hedonic models of OLS, GWR, and GWL focusing on the sales price of apartments in Seoul and compared those models in terms of model fit, prediction, and multicollinearity. As a result, local models appeared to be better than the global OLS on the whole, and in particular, the GWL appeared to be more explanatory and predictable than other models. Moreover, the GWL enabled to provide spatially different sets of price determinants which no multicollinearity exists. The GWL helps select the significant sets of independent variables from a high dimensional dataset, and hence will be a useful technique for large and complex spatial big data.

• Journal of Periodontal and Implant Science
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• v.46 no.6
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• pp.382-395
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• 2016

Purpose: Alendronate has been proposed as a local and systemic drug treatment used as an adjunct to scaling and root planing (SRP) for the treatment of periodontitis. However, its effectiveness has yet to be conclusively established. The purpose of the present meta-analysis was to assess the effectiveness of SRP with alendronate on periodontitis compared to SRP alone. Methods: Five electronic databases were used by 2 independent reviewers to identify relevant articles from the earliest records up to September 2016. Randomized controlled trials (RCTs) comparing SRP with alendronate to SRP with placebo in the treatment of periodontitis were included. The outcome measures were changes in bone defect fill, probing depth (PD), and clinical attachment level (CAL) from baseline to 6 months. A fixed-effect or random-effect model was used to pool the extracted data, as appropriate. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed using the Cochrane ${\chi}^2$ and $I^2$ tests. Results: After the selection process, 8 articles were included in the meta-analysis. Compared with SRP alone, the adjunctive mean benefits of locally delivered alendronate were 38.25% for bone defect fill increase (95% CI=33.05%-43.45%; P<0.001; $I^2=94.0%$), 2.29 mm for PD reduction (95% CI=2.07-2.52 mm; P<0.001; $I^2=0.0%$) and 1.92 mm for CAL gain (95% CI=1.55-2.30 mm; P<0.001; $I^2=66.0%$). In addition, systemically administered alendronate with SRP significantly reduced PD by 0.36 mm (95% CI=0.18-0.55 mm; P<0.001; $I^2=0.0%$) and increased CAL by 0.39 mm (95% CI=0.11-0.68 mm; P=0.006; $I^2=6.0%$). Conclusions: The collective evidence regarding the adjunctive use of alendronate locally and systemically with SRP indicates that the combined treatment can improve the efficacy of non-surgical periodontal therapy on increasing CAL and bone defect fill and reducing PD. However, precautions must be exercised in interpreting these results, and multicenter studies evaluating this specific application should be carried out.

• Journal of The Korean Association For Science Education
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• v.32 no.4
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• pp.686-702
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• 2012

This study investigated the impact of grouping methods on free inquiry implementation through the use of mixed research methods. Some 113 7th graders and 2 science teachers in two middle schools participated in this study. The 113 students who participated in this study were grouped by homogeneity and heterogeneity according to scientific inquiry skills and personality types respectively, and performed free inquiry activities on the same subject for three weeks. Data were collected by means of a test on science inquiry skills and from focus group interviews with 36 students and in-depth interviews with 2 teachers. The quantitative results of this study showed that homogeneous grouping was more effective than heterogeneous grouping in improvement of scientific inquiry skills. Meanwhile, the qualitative results revealed both the students and teachers perceived that it was effective to compose a small group according to their affective quality than their cognitive quality. Particularly, most of the students preferred the method of small group from the personality types. Some students and both teachers proposed that it is necessary to collect enough information on students and to use them in mixture with the method of small group according to the affective quality.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5761-5767
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• 2013

The potential correlation of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with hepatocellular carcinoma (HCC) susceptibility is ambiguous. Taking account of inconsistent results of previous meta-analyses and new emerging literatures, we conducted a meta-analysis covering 15 case-control datasets to evaluate the relationship. Relevant studies from Medline, Embase and CNKI were retrieved. A fixed-effect model or a random-effect model, depending on between-study heterogeneity, were applied to estimate the association between XRCC1 polymorphism Arg399Gln and HCC risk with the results presented as odds ratios (ORs) and 95% confidence intervals (95% CIs). In accordance with Hardy-Weinberg equilibrium, 15 studies with data for 6,556 individuals were enrolled in this systematic review. For overall HCC,thr XRCC1 polymorphism Arg399Gln was significantly associated with HCC susceptibility in a homozygote model as well as in a dominant model (G/G vs. A/A, OR=1.253, p=0.028; G/G+A/G vs. A/A, OR= 1.281, p=0.047, respectively), but not in a heterozygote model (A/G vs. A/A, OR=1.271, p=0.066) or a recessive model (G/G vs. A/G + A/A, OR= 1.049, p=0.542). Similar results were also observed on stratification analysis by ethnicity (A/G vs. A/A, OR=1.357, p=0.025; G/G vs. A/A, OR=1.310, p=0.011; G/G+A/G vs. A/A, OR= 1.371, p=0.013). However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified. No publication bias was found in this study. In conclusion, the XRCC1 Arg399Gln polymorphism contributes to HCC susceptibility. Due to the lack of studies in Western countries, further large-sample and rigorous studies are needed to validate the findings.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5177-5182
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• 2012

Purpose: To compare the efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitormonotherapy (EFGR-TKIs: gefitinib or erlotinib) with standard second-line chemotherapy (single agent docetaxel or pemetrexed) in previously treated advanced non-small-cell lung cancer (NSCLC). Methods: We systematically searched for randomized clinical trials that compared EGFR-TKI monotherapy with standard second-line chemotherapy in previously treated advanced NSCLC. The end points were overall survival (OS), progression-free survival (PFS), overall response rate (ORR), 1-year survival rate (1-year SR) and grade 3 or 4 toxicities. The pooled hazard ratio (HR) or risk ratio (RR), with their corresponding 95% confidence intervals (CI) were calculated employing fixed- or random-effects models depending on the heterogeneity of the included trials. Results: Eight randomized controlled trials (totally 3218 patients) were eligible. Our meta-analysis results showed that EGFR-TKIs were comparable to standard second-line chemotherapy for advanced NSCLC in terms of overall survival (HR 1.00, 95%CI 0.92-1.10; p=0.943), progression-free survival (HR 0.90, 95%CI 0.75-1.08, P=0.258) and 1-year-survival rate (RR 0.97, 95%CI 0.87-1.08, P=0.619), and the overall response rate was higher in patients who receiving EGFR-TKIs(RR 1.50, 95%CI 1.22-1.83, P=0.000). Sub-group analysis demonstrated that EGFR-TKI monotherapy significantly improved PFS (HR 0.73, 95%CI: 0.55-0.97, p=0.03) and ORR (RR 1.96, 95%CI: 1.46-2.63, p=0.000) in East Asian patients, but it did not translate into increase in OS and 1-year SR. Furthermore, there were fewer incidences of grade 3 or 4 neutropenia, febrile neutropenia and neutrotoxicity in EGFR-TKI monotherapy group, excluding grade 3 or 4 rash. Conclusion: Both interventions had comparable efficacy as second-line treatments for patients with advanced NSCLC, and EGFR-TKI monotherapy was associated with less toxicity and better tolerability. Moreover, our data also demonstrated that EGFR-TKImonotherapy tended to be more effective in East Asian patients in terms of PFS and ORR compared with standard second-line chemotherapy. These results should help inform decisions about patient management and design of future trials.

• Journal of Korean Society of Forest Science
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• v.96 no.6
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• pp.730-736
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• 2007

The heterogeneity of forest environment plays an important role in the structure and dynamics of tree population, the composition of forest community, and the maintenance of species diversity. Based upon the research data of the nine hectare permanent plot in the typical mixed broadleaved-Korean pine forest, this study was conducted to analyze the characteristics of spatial pattern of Acer tegmentosum population for seedlings, saplings, and living and dead trees so as to evaluate the effect of micro-topography on spatial pattern of the species. The results noted that A. tegmentosum preferred to gentle slopes. There was no difference in density of seedlings by the variation of aspect, but the density of saplings, and living and dead trees was high on the western and southeastern slopes. Living trees of A. tegmentosum showed the clumped pattern for all scales within 150 m and highest at the scale of 30 m. Dead stems of the species indicated the clumped pattern within 111 m, highest at the scale of 72 m, and random pattern beyond the scale of 111 m (P < 0.01 ). The similarity of occurrence by developmental stages of A. tegmentosum showed that seedlings vs. saplings, saplings vs. living trees, and living trees vs. dead stems had highly positive correlation to each other, respectively (P < 0.01 ), indicating that the occurrence of previous developmental stages was positively correlated to following stages.

• Environmental and Resource Economics Review
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• v.14 no.2
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• pp.337-379
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• 2005

This choice experiments study values the non-market benefits of water quality improvements in Paldang Reservoir and Han River, located in Korea. A fractional factorial orthogonal design was used to produce four different choice sets per respondent, before employing choice examples to screen out irrational responses. The panel mixed logit model (with normal distributions for the attributes) fit the data best, indicating that allowing for both heterogeneous preferences across households and correlation between repeated choices may represent actual choice behaviors best of all the estimated models. The significant standard deviations of the random attributes suggest that the taste for each attribute may vary considerably in the population. The annual benefits to the Seoul Metropolitan area for a small (large) enhancement of the clarity of water, a gradual removal of unpleasant waters, and a gradual improvement in biodiversity, were estimated to be some 1.5 trillion (1.7 trillion) Won, 2 trillion Won, and 1.7 trillion Won, respectively, with 1.8~2.6 trillion Won for at least two of them occurring together. The study also discusses potential biases germane to choice experiments studies of this type.