• 제목/요약/키워드: Damaged

검색결과 6,104건 처리시간 0.037초

급성 간손상 실험동물에 Cyclohexanone투여가 Oxygen Free Radical 대사효소 활성에 미치는 영향 (Effect of Cyclohexanone Treatment on the Activities of Oxygen Free Radical Metabolizing Enzyme in the Liver Damaged Rats)

  • 김현희;조현성;윤종국
    • 한국환경보건학회지
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    • 제28권2호
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    • pp.81-88
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    • 2002
  • Effect of cyclohexanone treatment on the activities oxygen free radical and cyclohexanone metabolizing enzyme in acute liver damaged rats, was investigated. Acute liver damage was induced in rats with pretreatment of 50% $CCl_4$ in olive oil(0.1ml/100g body wt) intraperitoneally 3 times every other day. Cyclohexanone(1.56g/kg body wt, i.p.) was administered to the animals 24 hours after the last Pretreatment of CC1$_4$. Rats were sacrificed at 4 hours after injection of cyclohexanone. On the basis of liver weight/body weight(%), serum levels alanine aminotransferase activity and hepatic protein content, cyclohexanone treatment to acute liver damaged animals led to the more enhanced liver damage. On the other hand, injection of cyclohexanone to the rats led to the increased activities of hepatic cytochrome P-450 dependent aniline hydroxylase and xanthine oxidase. Furthermore, by treatment of cyclohexanone to the acute liver damaged rats hepatic xanthine oxidase activity was more increased than the $CCl_4$ treated rats. In case of oxygen free radical scavenging system, the hepatic glutathione content and the activities of hepatic glutathione S-transferase, catalase, superoxide dismutase were generally increased by injection of cyclohexanone to rats, and the hepatic glutathione content, catalase and alcohol dehydrogenase activities were more decreased in liver damaged rats by the treatment of cyclohexanone. In conclusion, the cyclohexanone treatment to acute liver damaged rats led to enhancement of liver damage that may be due to oxygen free radical together with cyclohexanone.

Effect of Cyclohexanone Treatment on the Serum Levels of Glutathione S-Transferase Activities in Acute Liver Damaged Rats

  • Park, Hye-Jung;Yoon, Chong-Guk
    • 대한의생명과학회지
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    • 제7권4호
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    • pp.191-196
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    • 2001
  • To evaluate an effect of cyclohexanone (CHO) treatment on the serum levels of glutathione S-transferase (GST) activity in acute liver damaged animals, acute liver damage was induced in rats with pretreatment of 50% $CCl_4$ in olive oil (0.1 ml/100 g body wt) intraperitoneally 14 times every other day. To liver damaged rats, CHO (1.56 g/kg body wt, i. p.) was injected once and then rats were sacrificed at 4 hours after injection of CHO. Increasing rate of GST activity to the control in serum was higher in CHO-treated rats pretreated with CCL$_4$ than the $CCl_4$-pretreated those. All the more, the injection of CHO to the liver damaged rats led to more enhanced liver damage on the basis of liver functional findings, i. e., serum levels of alanine aminotransferase (ALT) activity, liver weight per body weight, and malondialdehyde content. The changing pattern of serum ALT activity was similar with that of GST activity, whereas that of liver in both enzymes differed more or less from each other; the liver GST activity in CHO-treated rats pretreated with $CCl_4$ being more increased tendency than that of $CCl_4$-pretreated rats. Concomitantly the injection of CHO showed a increasing tendency of liver GST activity compared with the control. Furthermore, CHO injection to the liver damaged rats showed somewhat higher Vmax in the kinetics of liver GST enzymes. In conclusion, injection of CHO to the liver damaged animals led to more increased activity of serum GST, and it may be chiefly caused by the alteration of membrane permeability.

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공간통계학적 방법에 의한 소나무 재선충 피해의 자연적 확산유형분석 (Natural Spread Pattern of Damaged Area by Pine Wilt Disease Using Geostatistical Analysis)

  • 손민호;이우균;이승호;조현국;이준학
    • 한국산림과학회지
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    • 제95권3호
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    • pp.240-249
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    • 2006
  • 최근, 소나무재선충(Bursaphelenchus xylophilus)에 의한 소나무림의 피해에 대한 사회적 심각성이 크게 대두되고 있다. 소나무 재선충에 의한 산림피해는 피해지 내에서는 매개충인 솔수염하늘소의 자연적인 영역확장에 의해 확산되는 반면, 전국적으로는 감염목의 인위적 반출 및 이동에 의해 확산이 진행되고 있다. 본 연구에서는 부산 대변항의 재선충 피해지내에서 항공사진 및 현지조사에 의해 피해목의 공간적인 위치를 파악하였고, 공간통계학적인 방법을 통하여 피해목의 공간분포유형, 피해발생과 지형인자간의 관계를 분석하였다. 또한, 지형공간자료를 통계학적 Tree 모형에 적용한 CART(Classification and Regression Trees)모형을 이용하여 재선충 피해의 자연적인 확산 예측 지도를 작성하였다. 본 연구를 통해 공간통계학적인 분석과 CART모형이 소나무재선충 피해의 공간분포 및 자연적 확산유형을 파악하는데 유용한 도구로 활용될 수 있음을 확인할 수 있었다.

소맥분 제분시 발생되는 손상전분이 제빵 적성에 미치는 영향 (Effects of Attrition Milling in Wheat Flour on Starch Damaged of Dough and Bread Baking Properties)

  • 주옥수;정용면
    • 한국식품저장유통학회지
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    • 제8권4호
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    • pp.434-441
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    • 2001
  • 본 연구에 세는 제빵용 소맥분의 손상전분 함량을 비교 분석하여 최적의 작업조건 설정과 제빵 품질을 향상시킬 목적으로 손상전분 함량을 각각 달리하여 반죽의 물리적 특성 및 제빵 적성을 검토하였다. DNS와 CWRS 및 SW 등의 소맥을 제분하여 손상전분 함량 6.5%, 8.2%, 9.0%, 9.5% 및 10.5%를 함유한 시료로 제조한 반죽의 물리적 및 이화학적 특성인 farinogram, extensogram, amylogram 등을 조사하였으며, 또한 제빵 적성 실험으로 rheometer를 이용하여 제빵의 경도 및 비용적과 관능검사 등으로 품질을 평가하였다. 제빵 적성 실험에서 손상전분 6.5%, 10.5%에서는 효소활성이 강하여 반죽이 연약해져 선택, 모양이 나쁘게 나타났으며, amylogram특성 실험 결과 최고 점도가 900 B.U인 손상전분 9.5%에서 빵의 부피, fermentation tolerance가 증가하였다. extensogram에서 신장 저항성(R)값이 45분, 90분, 135분으로 시간이 갈수록 R값이 현저하게 증가하는 손상전분 함량 9.0%와 9.5%함유된 밀가루의 반죽 공정이 쉽고 장시간 발효에 잘 견디며 좋은 조직의 빵이 생산되었으며, 종합적인 관능 평가에서도 조직이 부드럽고 기공이 균일하며 씹힘성, 부피감 및 향 등이 가장좋은 제빵으로 나타났다.

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The Survey about the Degree of Damage of Radiation-Protective Shields in Operation Room

  • Ryu, Jae Sung;Baek, Seung Woo;Jung, Cheol Hee;Cho, Suk Ju;Jung, Eu Gene;Kim, Hae Kyoung;Kim, Jae Hun
    • The Korean Journal of Pain
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    • 제26권2호
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    • pp.142-147
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    • 2013
  • Background: Medical doctors who perform C-arm fluoroscopy-guided procedures are exposed to X-ray radiation. Therefore, radiation-protective shields are recommended to protect these doctors from radiation. For the past several years, these protective shields have sometimes been used without regular inspection. The aim of this study was to investigate the degree of damage to radiation-protective shields in the operating room. Methods: This study investigated 98 radiation-protective shields in the operation rooms of Konkuk University Medical Center and Jeju National University Hospital. We examined whether these shields were damaged or not with the unaided eye and by fluoroscopy. Results: There were seventy-one aprons and twenty-seven thyroid protectors in the two university hospitals. Fourteen aprons (19.7%) were damaged, whereas no thyroid protectors (0%) were. Of the twenty-six aprons, which have been used since 2005, eleven (42.3%) were damaged. Of the ten aprons, which have been used since 2008, none (0%) was damaged. Of the twenty-three aprons that have been used since 2009, two (8.7%) of them were damaged. Of the eight aprons used since 2010, one (12.3%) was damaged. Of the four aprons used since 2011, none (0%) of them were damaged. The most common site of damage to the radiation-protective shields was at the waist of the aprons (51%). Conclusions: As a result, aprons that have been used for a long period of time can have a higher risk of damage. Radiation-protective shields should be inspected regularly and exchanged for new products for the safety of medical workers.

콩 탈곡손상 절감을 위한 콩 탈곡통 개발 (Development of Threshing Cylinder for Reduction of Soybean Seed Damage)

  • 조용진;이규승
    • Journal of Biosystems Engineering
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    • 제35권6호
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    • pp.380-386
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    • 2010
  • This study was carried out to develop soybean thresher which is able to reduce the soybean threshing damage in comparison to the conventional thresher. A threshing cylinder with different diameter of 480 and 384 mm at each end and with one quarter disc pegs of 60 mm radius was developed and attached to the prototype thresher. A conventional thresher which has a threshing cylinder with $\wedge$ type threshing pegs and same diameter of 480 mm at each end was used for comparative test. A series of comparative performance test was conducted using sun-yu and chung-ja soybean. For sun-yu bean, which is white and usually used for soybean paste and soy sauce, the ratio of damaged beans of prototype ranged 2-3% for 330-360 rpm which is recommended cylinder speed by manufacturer. The ratio of damaged beans of conventional thresher was 3-4% for the same range of cylinder speed. chung-ja beans with black color usually shows high damaged ratio compared with white beans, thus cylinder speed of 250-300 rpm is recommended by manufacturer to reduce the damaged ratio. For this range of cylinder speed, the damaged ratio of prototype was 1.3-1.4% and it was 2.7-6.1% for the conventional thresher. Thus prototype is able to reduce the damaged ratio 1.5-5.0% compared with conventional thresher. Prototype shows 0.4% of unthreshed soybean ratio for sun-yu bean in the optimum range of cylinder speed and it was 0.87% for the conventional thresher. For chung-ja bean, the ratio of unthreshed soybean was almost same for both prototype and conventional thresher with the value of 4.0%. The reason of high unthreshed soybean ratio for chung-ja bean compared sun-yu bean is due to the high seed moisture content of 29.11% which is much higher than that of the recommended.

Detection of The Pine Trees Damaged by Pine Wilt Disease using High Resolution Satellite and Airborne Optical Imagery

  • Lee, Seung-Ho;Cho, Hyun-Kook;Lee, Woo-Kyun
    • 대한원격탐사학회지
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    • 제23권5호
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    • pp.409-420
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    • 2007
  • Since 1988, pine wilt disease has spread over rapidly in Korea. It is not easy to detect the damaged pine trees by pine wilt disease from conventional remote sensing skills. Thus, many possibilities were investigated to detect the damaged pines using various kinds of remote sensing data including high spatial resolution satellite image of 2000/2003 IKONOS and 2005 QuickBird, aerial photos, and digital airborne data, too. Time series of B&W aerial photos at the scale of 1:6,000 were used to validate the results. A local maximum filtering was adapted to determine whether the damaged pines could be detected or not at the tree level from high resolution satellite images, and to locate the damaged trees. Several enhancement methods such as NDVI and image transformations were examined to find out the optimal detection method. Considering the mean crown radius of pine trees, local maximum filter with 3 pixels in radius was adapted to detect the damaged trees on IKONOS image. CIR images of 50 cm resolution were taken by PKNU-3(REDLAKE MS4000) sensor. The simulated CIR images with resolutions of 1 m, 2 m, and 4 m were generated to test the possibility of tree detection both in a stereo and a single mode. In conclusion, in order to detect the pine tree damaged by pine wilt disease at a tree level from satellite image, a spatial resolution might be less than 1 m in a single mode and/or 1 m in a stereo mode.

Strengthening of concrete damaged by mechanical loading and elevated temperature

  • Ahmad, Hammad;Hameed, Rashid;Riaz, Muhammad Rizwan;Gillani, Asad Ali
    • Advances in concrete construction
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    • 제6권6호
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    • pp.645-658
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    • 2018
  • Despite being one of the most abundantly used construction materials because of its exceptional properties, concrete is susceptible to deterioration and damage due to various factors particularly corrosion, improper loading, poor workmanship and design discrepancies, and as a result concrete structures require retrofitting and strengthening. In recent times, Fiber Reinforced Polymer (FRP) composites have substituted the conventional techniques of retrofitting and strengthening of damaged concrete. Most of the research studies related to concrete strengthening using FRP have been performed on undamaged test specimens. This contribution presents the results of an experimental study in which concrete specimens were damaged by mechanical loading and elevated temperature in laboratory prior to application of Carbon Fiber Reinforced Polymer (CFRP) sheets for strengthening. The test specimens prepared using concrete of target compressive strength of 28 MPa at 28 days were subjected to compressive and splitting tensile testing up to failure and the intact pieces of the failed specimens were collected for the purpose of repair. In order to induce damage as a result of elevated temperature, the concrete cylinders were subjected to $400^{\circ}C$ and $800^{\circ}C$ temperature for two hours duration. Concrete cylinders damaged under compressive and split tensile loads were re-cast using concrete and rich cement-sand mortar, respectively and then strengthened using CFRP wrap. Concrete cylinders damaged due to elevated temperature were also strengthened using CFRP wrap. Re-cast and strengthened concrete cylinders were tested in compression and splitting tension. The obtained results revealed that re-casting of specimens damaged by mechanical loadings using concrete & mortar, and then strengthened by single layer CFRP wrap exhibited strength even higher than their original values. In case of specimens damaged by elevated temperature, the results indicated that concrete strength is significantly dropped and strengthening using CFRP wrap made it possible to not only recover the lost strength but also resulted in concrete strength greater than the original value.

Damaged cable detection with statistical analysis, clustering, and deep learning models

  • Son, Hyesook;Yoon, Chanyoung;Kim, Yejin;Jang, Yun;Tran, Linh Viet;Kim, Seung-Eock;Kim, Dong Joo;Park, Jongwoong
    • Smart Structures and Systems
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    • 제29권1호
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    • pp.17-28
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    • 2022
  • The cable component of cable-stayed bridges is gradually impacted by weather conditions, vehicle loads, and material corrosion. The stayed cable is a critical load-carrying part that closely affects the operational stability of a cable-stayed bridge. Damaged cables might lead to the bridge collapse due to their tension capacity reduction. Thus, it is necessary to develop structural health monitoring (SHM) techniques that accurately identify damaged cables. In this work, a combinational identification method of three efficient techniques, including statistical analysis, clustering, and neural network models, is proposed to detect the damaged cable in a cable-stayed bridge. The measured dataset from the bridge was initially preprocessed to remove the outlier channels. Then, the theory and application of each technique for damage detection were introduced. In general, the statistical approach extracts the parameters representing the damage within time series, and the clustering approach identifies the outliers from the data signals as damaged members, while the deep learning approach uses the nonlinear data dependencies in SHM for the training model. The performance of these approaches in classifying the damaged cable was assessed, and the combinational identification method was obtained using the voting ensemble. Finally, the combination method was compared with an existing outlier detection algorithm, support vector machines (SVM). The results demonstrate that the proposed method is robust and provides higher accuracy for the damaged cable detection in the cable-stayed bridge.

바질 오일의 손상모발 개선효과에 관한 연구 (A Study of Oil of Basil Extract on Improvement of Hair Damage)

  • 김주섭
    • 한국응용과학기술학회지
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    • 제39권2호
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    • pp.294-302
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    • 2022
  • 본 연구는 바질 오일을 첨가한 모질 개선 제형제를 제조 후 손상된 모발에 도포하여 손상 모발의 개선 효과를 알아보고자 하였다. 실험원료로 바질 오일 함량을 0 g, 3 g 6 g, 9 g 으로 다르게 하여 펌베이스제에 첨가하여 제형제를 제조하였다. 제조한 제형제로 8레벨의 탈색한 시료 모발에 도포하였다. 각 시료와 손상모를 측정하여 비교 분석하였다. 측정방법은 모질 개선 효과를 알기 위해 인장강도, 메틸렌블루를 이용한 흡광도, 광택을 측정하였다. 연구결과의 신뢰성을 위해 통계분석을 하였다. 연구결과로 인장강도 측정결과는 바질 오일을 첨가하여 도포 한 모든 시료에서 손상모보다 인장강도가 증가함을 알 수 있었다. 메틸렌블루를 이용한 흡광도 분석결과 모든 시료에서 손상모보다 흡광도가 감소함을 알 수 있었다. 광택 측정결과는 모든 시료에서 손상모보다 광택이 증가함을 알 수 있었다. 결론은 바질 오일이 손상된 모발에 개선 효과가 있는 것을 알 수 있었다. 차후 다양한 오일의 종류와 연구방법으로의 연구가 필요하다.