• Title/Summary/Keyword: Damage rate

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Sea Tangle Supplementation Alters Intestinal Morphology in Streptozotocin-induced Diabetic Rats and Lowers Glucose Absorption

  • Lee, Kyeung-Soon;Seo, Jung-Sook;Choi, Young-Sun
    • Food Science and Biotechnology
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    • v.16 no.6
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    • pp.879-883
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    • 2007
  • This study examined whether dietary supplementation with sea tangle alters the intestinal morphology of streptozotocin-induced diabetic rats and affects the glucose absorption rate. Forty male Sprague-Dawley rats were divided into 2 groups and fed either a control (AIN76-based) diet or a sea tangle-supplemented diet. After 3 weeks, 10 rats in each group received an intramuscular injection of streptozotocin (45 mg/kg BW), and feeding was continued for 3 additional weeks. Dietary supplementation with sea tangle resulted in a lower fasting plasma glucose level compared with the control diet in diabetic rats. Scanning electron micrographs revealed serious damage to the jejunal villi of diabetic rats fed the control diet, whereas supplementation with sea tangle alleviated the damage. In a separate experiment, 20 male Sprague-Dawley rats were divided into 2 groups and fed either a control diet or a sea tangle-supplemented diet for 5 weeks, and fasted rats were subjected to in situ single-pass perfusion. The glucose absorption rate determined in the absence of digesta was decreased by 34% in the jejunum of rats fed a sea tangle diet compared with those fed a control diet. In conclusion, sea tangle supplementation lowered glucose absorption rate, altered intestinal morphology, and appeared to protect villi from damage caused by diabetes mellitus.

The Protective Effects of Ganoderma lucidum on the DNA Damage and Mutagenesis (DNA손상 및 돌연변이에 대한 명지버섯의 방어효능)

  • 이길수;공석경;최수영
    • Biomolecules & Therapeutics
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    • v.11 no.2
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    • pp.139-144
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    • 2003
  • Ganoderma lucidum is commonly known as medically potent mushroom, which has been widely used in China and other oriental countries for the treatment of various diseases, including cancer. In this report, we investigated the anti-oxidant and protective effect of Ganodema lucidum extract (GLE) against the DNA damage induced by free radical and U.V. In the assay of cell growth inhibition, the inhibitory cell growth rate induced by hydroxyl radical was dose-dependently decreased by GLE. This results support that GLE has a detoxifying activity against cytotoxicity of hydroxyl radical in E. coli cell. GLE also protected ColE1 plasmid DNA damage in the concentration of 200$\mu\textrm{g}$ per reaction on the DNA fragmentation assay. The nuclear tailing by hydrogen peroxide in single cell gel electrophoresis(SCGE) was decreased by GLE in the concentration of 50$\mu\textrm{g}$/ml. These data indicate that Ganoderma lucidum has an anti-oxidative activity to hydrogen peroxide. The mutation rate after irradiation of U.V. was reduced by 50$\mu\textrm{g}$/ml GLE and total number of Rif (Rifampicin) resistant mutants was decreased in a concentration dependent manner when added the GLE exogenously in a culture media. According to the results, it is likely that GLE has not only an anti-oxidative activity to hydroxyl radical but also an anti-mutagenic activity to U.V. mutagenesis.

Corrosion Assessment by Using Risk-Based Inspection Method for Petrochemical Plant - Practical Experience

  • Choi, Song-Chun;Song, Ki-Hun
    • Corrosion Science and Technology
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    • v.8 no.3
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    • pp.119-125
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    • 2009
  • Corrosion assessment has a number of uses but the use considered here is as a precursor to Risk-Based Inspection (RBI) planning. Systematic methods consisting of technical modules of RBI program were used to assess the effect of specific corrosion mechanism on the probability of failure in equipments of petrochemical plants. Especially in part of the damage and corrosion assessment, screening step involved evaluating the combinations of process conditions and construction materials for each equipment item in order to determine which damage mechanisms are potentially active. For general internal corrosion, either API 510 or API 570 was applied as the damage rate in the calculation to determine the remaining life and inspection frequency. In some cases, a measured rate of corrosion may not be available. The technical modules of RBI program employ default values for corrosion, typically derived from published data or from experience with similar processes, for use until inspection results are available. This paper describes the case study of corrosion and damage assessment by using RBI methodology in petrochemical plant. Specifically, this paper reports the methodology and the results of its application to the petrochemical units using the $KGS-RBI^{TM}$ program, developed by the Korea Gas Safety Corporation to suit Korean situation in conformity with API 581 Codes.

Study on the Cavitation Damage of Cupronickel(70/30) Tube for Gas Absorption Refrigeration Machine

  • Lim, Uh-Joh;Jeong, Ki-Cheol;Yun, Byoung-Du
    • Journal of Advanced Marine Engineering and Technology
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    • v.28 no.2
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    • pp.332-337
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    • 2004
  • The use of gas absorption refrigeration machine has considerably increased because of the shortage of the electric power in the summer and the regulation of freon refrigerant. Gas absorption refrigeration machine consists of a condenser, a heat exchanger. supplying pipes, a radiator etc, This system is likely to be corroded by acid. dissolved oxygen and gases, Cavitation erosion-corrosion by flow velocity of cooling water may happen in absorption refrigeration machine. In these cases. erosion and corrosion occur simultaneously. Then, it makes a serious damage with synergy effect. Therefore, this paper was studied on the cavitation damage of cupronickel(70/30) tube for gas absorption refrigeration machine, In the $30^{\circ}C$ tap water, linear polarization test and anodic polarization test were carried out for copper(C1220T-OL) and cupronickel(70/30) tube. Also, cavitation erosion-corrosion behavior of cupronickel (70/30) tube was considered, The main results are as following: (1) In the linear test, the corrosion current density of cupronickel(70/30) is higher than that of copper. (2) The erosion-corrosion rate of cupronickel(70/30) displayed later tendency than that of copper by vibratory cavitation in cooling water. (3) In cooling water, the progress mechanism of erosion-corrosion rate of copper and cupronickel(70/30) follows a pattern of incubation, acceleration, attenuation and a steady state period.

Tracking Analysis of User Privacy Damage using Smartphone (스마트폰 사용으로 인한 사용자 프라이버시 피해 현황 분석)

  • Jeong, Yoon-Su
    • Journal of Convergence Society for SMB
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    • v.4 no.4
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    • pp.13-18
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    • 2014
  • The usage rate of user due to advances in smartphone development is higher than the usage rate to use a PC. However, smartphone usage popularized research to protect sensitive information, such as smart phone users personal information, financial information is a small state. In this paper, we analyzed the various vulnerabilities in smartphone studies to date have been looking into the corresponding port smart consumer dispute resolution methods and criteria for smartphone security attack methods and analysis. In particular, the threat of such a network, malware, Peep attack of the security threats arising from the smartphone they can avoid or mitigate threats to minimize the smartphone security damage is done to the disclosure of personal information, such as direct damage or financial loss the analysis of that method.

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Corrosion Damage Behavior of STS 304 and STS 415 for Reactor Coolant Pump during Ultrasonic-Chemical Decontamination Process (원자로 냉각재 펌프용 STS 304와 STS 415의 초음파-화학제염 공정 시 부식 손상 거동)

  • Hyeon, Gwang-Ryong;Park, Jae-Cheol;Han, Min-Su;Kim, Seong-Jong
    • Journal of the Korean institute of surface engineering
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    • v.51 no.4
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    • pp.218-223
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    • 2018
  • In this study, we proposed a new ultrasonic-chemical decontamination process for decontaminating radioactive corrosion products during the maintenance of reactor coolant pump (RCP). The actual decontamination process was reproduced in the laboratory. And the corrosion characteristics of stainless steel (STS), constituting the RCP interior parts, were examined. The weight-loss measurment and polarization experiment were carried out in order to determine the corrosion characteristics of STS 304 and STS 415 by repeated decontamination processes. The STS 304 presented a little corrosion damage, which was almost indistinguishable from visual observation. The weight-loss rate of STS 304 was also significantly lower. On the other hand, STS 415 showed severe corrosion damage on its surface, greater weight-loss rate and higher corrosion current density than STS 304.

An approach for optimal sensor placement based on principal component analysis and sensitivity analysis under uncertainty conditions

  • Beygzadeh, Sahar;Torkzadeh, Peyman;Salajegheh, Eysa
    • Structural Monitoring and Maintenance
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    • v.9 no.1
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    • pp.59-80
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    • 2022
  • In the present study, the objective is to detect the structural damages using the responses obtained from the sensors at the optimal location under uncertainty conditions. Reducing the error rate in damage detection process due to responses' noise is an important goal in this study. In the proposed algorithm for optimal sensor placement, the noise of responses recorded from the sensors is initially reduced using the principal component analysis. Afterward, the optimal sensor placement is obtained by the damage detection equation based sensitivity analysis. The sensors are placed on degrees of freedom corresponding to the minimum error rate in structural damage detection through this procedure. The efficiency of the proposed method is studied on a truss bridge, a space dome, a double-layer grid as well as a three-story experimental frame structure and the results are compared. Moreover, the performance of the suggested method is compared with three other algorithms of Average Driving Point Residue (ADPR), Effective Independence (EI) method, and a mass weighting version of EI. In the examples, young's modulus, density, and cross-sectional areas of the elements are considered as uncertainty parameters. Ultimately, the results have demonstrated that the presented algorithm under uncertainty conditions represents a high accuracy to obtain the optimal sensor placement in the structures.

X-Ray Diffraction line profile analysis of defects and precipitates in high displacement damage neutron-irradiated austenitic stainless steels

  • Shreevalli M.;Ran Vijay Kumar;Divakar R.;Ashish K.;Padmaprabu C.;Karthik V.;Archna Sagdeo
    • Nuclear Engineering and Technology
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    • v.56 no.1
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    • pp.114-122
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    • 2024
  • Irradiation-induced defects and the precipitates in the wrapper material of the Indian Fast Breeder Test Reactor (FBTR), SS 316 are analyzed using the synchrotron source-based Angle Dispersive X-Ray Diffraction (ADXRD) technique with X-rays of energy 17.185 keV (wavelength ~0.72146 Å). The differences and similarities in the high displacement damage samples as a function of dpa (displacement per atom) and dpa rate in the range of 2.9 × 10-7- 9 × 10-7 dpa/s are studied. Ferrite and M23C6 are commonly observed in the present set of high displacement damage 40-74 dpa SS 316 samples irradiated at temperatures in the range of 400-483 ℃. Also, the dislocation density has increased as a function of the irradiation dose. The X-ray diffraction peak profile parameters quantified such as peak shift and asymmetry show that the irradiation-induced defects are sensitive to the dpa rate-irradiation temperature combinations. The increase in yield strength as a function of displacement damage is also correlated to the dislocation density.

Structural damage identification based on modified Cuckoo Search algorithm

  • Xu, H.J.;Liu, J.K.;Lv, Z.R.
    • Structural Engineering and Mechanics
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    • v.58 no.1
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    • pp.163-179
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    • 2016
  • The Cuckoo search (CS) algorithm is a simple and efficient global optimization algorithm and it has been applied to figure out large range of real-world optimization problem. In this paper, a new formula is introduced to the discovering probability process to improve the convergence rate and the Tournament Selection Strategy is adopted to enhance global search ability of the certain algorithm. Then an approach for structural damage identification based on modified Cuckoo search (MCS) is presented. Meanwhile, we take frequency residual error and the modal assurance criterion (MAC) as indexes of damage detection in view of the crack damage, and the MCS algorithm is utilized to identifying the structural damage. A simply supported beam and a 31-bar truss are studied as numerical example to illustrate the correctness and efficiency of the propose method. Besides, a laboratory work is also conducted to further verification. Studies show that, the proposed method can judge the damage location and degree of structures more accurately than its counterpart even under measurement noise, which demonstrates the MCS algorithm has a higher damage diagnosis precision.

Creep Design of Type 316LN Stainless Steel by K-R Damage Theory (K-R 손상이론에 의한 316LN 스테인리스강의 크리프 설계)

  • Kim, U-Gon;Kim, Dae-Hwan;Ryu, U-Seok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.25 no.2
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    • pp.296-303
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    • 2001
  • Kachanov-Rabotnov(K-R) creep damage theory was reviewed, and applied to design a creep curve for type 316LN stainless steel. Seven coefficients used in the theory, i.e., A, B, k, m, λ, r, and q were determined, and their physical meanings were analyzed clearly. In order to quantify a damage parameter ($\omega$), cavity amount was measured in the crept specimen taken from interrupted creep test with time variation, and then the amount was reflected into K-R damage equations. Coefficient λ, which is regarded as a creep tolerance feature of a material, increased with creep strain. Mater curve with λ=2.8 was well coincided with an experimental one to the full lifetime. The relationship between damage parameter and life fraction was matched with the theory at exponent ${\gamma}$=24 value. It is concluded that K-R damage equation was reliable as the modelling equation for type 316LN stainless steel. Coefficient data obtained from type 316LN stainless steel can be utilized for life prediction of operating material.