• Journal of the Korean Geotechnical Society
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• v.30 no.9
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• pp.41-55
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• 2014

In performing seismic analysis of tunnels, it is a common practice to ignore the rock joints and to assume that the rock mass surrounding the tunnel is continuous. The applicability of this assumption has not yet been validated in detail. This study performs a series of pseudo-static discrete element analyses to evaluate the effect of rock joint on the seismic response of tunnels. The parameters considered are joint intersection location, joint spacing, joint stiffness, joint dip, and interface stiffness. The results show that the joint stiffness has the most critical influence on the tunnel response. The tunnel response increases with the spacing, resulting in localized concentration of moment and shear stress. The response of the tunnel is the lowest for joints dipping at $45^{\circ}$. This is because large shear stresses result in rotation of the principal planes by $45^{\circ}$. In summary, the weathered and smooth, vertical or horizontal, and widely spaced joint set will significantly increase the tunnel response under seismic loading. The tunnel linings are shown to be most susceptible to damage due to induced shear stress, and therefore should be checked in the seismic design.

• Earthquakes and Structures
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• v.11 no.6
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• pp.1101-1121
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• 2016

Base isolation, one of the popular seismic protection approaches proven to be effective in practical applications, has been widely applied worldwide during the past few decades. As the techniques mature, it has been recognised that, the biggest issue faced in base isolation technique is the challenge of great base displacement demand, which leads to the potential of overturning of the structure, instability and permanent damage of the isolators. Meanwhile, drain, ventilation and regular maintenance at the base isolation level are quite difficult and rather time- and fund- consuming, especially in the highly populated areas. To address these challenges, a number of efforts have been dedicated to propose new isolation systems, including segmental building, additional storey isolation (ASI) and mid-storey isolation system, etc. However, such techniques have their own flaws, among which whipping effect is the most obvious one. Moreover, due to their inherent passive nature, all these techniques, including traditional base isolation system, show incapability to cope with the unpredictable and diverse nature of earthquakes. The solution for the aforementioned challenge is to develop an innovative vibration isolation system to realise variable structural stiffness to maximise the adaptability and controllability of the system. Recently, advances on the development of an adaptive magneto-rheological elastomer (MRE) vibration isolator has enlightened the development of adaptive base isolation systems due to its ability to alter stiffness by changing applied electrical current. In this study, an innovative semi-active storey isolation system inserting such novel MRE isolators between each floor is proposed. The stiffness of each level in the proposed isolation system can thus be changed according to characteristics of the MRE isolators. Non-dominated sorting genetic algorithm type II (NSGA-II) with dynamic crowding distance (DCD) is utilised for the optimisation of the parameters at isolation level in the system. Extensive comparative simulation studies have been conducted using 5-storey benchmark model to evaluate the performance of the proposed isolation system under different earthquake excitations. Simulation results compare the seismic responses of bare building, building with passive controlled MRE base isolation system, building with passive-controlled MRE storey isolation system and building with optimised storey isolation system.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.4
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• pp.635-650
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• 2017

Acoustic emission (AE) sensors have broadly used to monitor the damage of underground structures and tunnels. The reliability of measured signal is determined by the coupling condition of the AE sensors which are embedded in the target underground structure. To secure the reliability of health monitoring results, it is important to understand the characteristics of the coupling materials. In this study, laboratory tests were performed using portland cement, micro cement, and gypsum as coupling materials in order to verify the bleeding characteristics. The effective parameters for bleeding were determined to be water-cement ratio, material type, curing time, and injected volume of coupling materials. As a results of the experimental study, the bleeding rate increases with an increase in a water-cement ratio and an injected volume; for portland cement, water-cement ratio and injected volume effects are larger than the micro cement. However, curing time is not much effective for occurrence of the bleeding phenomenon. It is anticipated that this study may be useful for the selection of suitable coupling materials for installation of acoustic emission sensors.

• Journal of Korean Tunnelling and Underground Space Association
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• v.20 no.5
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• pp.839-854
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• 2018

This study was performed to evaluate the performance of GFRP plate reinforced segments for TBM tunnel support. Recently, the SFRC segment has been applied to prevent local damage such as reduction of the amount of reinforcing bars of the segment, crack control and breakage. However, the steel fiber used in the SFRC segment has a problem of durability deterioration due to fiber corrosion. Compared with the RC segment, the maximum flexural load reduction of the SFRC segment hinders the broad application range of the TBM tunnel segment. Therefore, GFRP plate was considered as a stiffener for the maximum load increase of SFRC segment, and structural synthetic fiber without corrosive concern was used as a substitute for steel fiber. The flexural performance of the segment was evaluated by using the type of reinforcing fiber and GFRP plate thickness as the main parameters. As a result, the maximum load and the flexural toughness were increased by 21.78~23.03% and 0.5~7.96%, respectively, as compared with the segments reinforced with reinforcing fiber and GFRP plate of 3 mm thickness.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2301-2305
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• 2016

Background: The early detection of anthracycline- induced cardiotoxicity is very important since it might be useful in prevention of cardiac decompensation. This study was designed with the intent of assessing the usefulness of cardiac troponin T (cTnT) and NT- Pro BNP estimation in early prediction of anthracycline induced cardiotoxicity. Materials and Methods: In this prospective study histologically proven breast cancer patients who were scheduled to receive anthracycline containing combination chemotherapy as a part of multimodality treatment were enrolled. Baseline cardiac evaluation was performed by echocardiography (ECHO) and biomarkers like cardiac troponin T (cTnT) and N terminal- pro brain natriuretic peptide (NT- Pro BNP). All patients underwent cTnT and NT- Pro BNP estimation within 24 hours of each cycle of chemotherapy and were followed up after 6 months of initiation of chemotherapy. Any changes in follow up ECHO were compared to ECHO at baseline and cTnT and NT- Pro BNP levels after each cycle of anthracycline-based chemotherapy. Results: Initial data were obtained for 33 patients. Mean change in left ventricular diastolic diameter (LVDD) within 6 months was $0.154{\pm}0.433cms$ (p value=0.049). Seven out of 33 patients had an increase in biomarker cTnT levels (p value=0.5). A significant change in baseline and follow up LVDD was observed in patients with raised cTnT levels (p value=0.026) whereas no change was seen in ejection fraction (EF) and left atrial diameters (LAD) within 6 months of chemotherapy. NT- Pro BNP levels increased in significant number of patients (p value ${\leq}0.0001$) but no statistically significant change was observed in the ECHO parameters within 6 months. Conclusions: Functional monitoring is a poorly effective method in early estimation of anthracycline induced cardiac dysfunction. Estimation of biomarkers after chemotherapy may allow stratification of patients in various risk groups, thereby opening window for interventional strategies in order to prevent permanent damage to the myocardium.

• Journal of the Korean Society of Food Science and Nutrition
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• v.31 no.4
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• pp.672-678
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• 2002

Oxidative stress contributes to cellular injury following clinical and experimental ischemia/reperfusion scenarios. Oxidative injury can induce cellular and nuclear damages that result in apoptotic cell death. We tested the hypothesis that the catechin flavonoid of (-)epigallocatechin gallate, a green tea polyphenol, inhibits hydrogen peroxide ($H_2O$$_2$)-induced apoptosis in human umbilical vein endothelial cells. The effect of apigenin, a flavone found in citrus fruits, on apoptosis parameters was also examined. A 30 min pulse treatment with 0.25 mM $H_2O$$_2$ decreased endothelial cell viability within 24 hrs by > 30% ; this was associated with nuclear condensation and biochemical DNA damage consistent with programmed cell death. In the 0.25 mM $H_2O$$_2$apoptosis model, 50${\mu}{\textrm}{m}$ (-)epigallocatechin gallate markedly increased cell viability with a reduction in the nuclear condensation and DNA fragmentation. In contrast, equimicromolar apigenin increased cell loss with intense DNA laddering, positive nick-end labeling and Hoechst 33258 staining. Thus, polyphenolic (-)epigallocatechin gallate, but not apigenin flavone, qualify as an antioxidant in apoptosis models caused by oxidative stress. Further work is necessary for elucidating the anti-apoptotic mechanisms of polyphenolic catechins.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.1
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• pp.149-156
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• 2018

Objective: Broilers show clear preference towards red color light (RL). However setting of an optimum light intensity is difficult since dim intensities that favor growth reduce welfare. This experiment was conducted to test the most effective RL intensity regimen (Dim [5 lux; DI] vs high [320 lux; HI]) in combination applied at different growth stages that favors for both performance and welfare. Methods: Complete randomize design was adopted with 6 replicates. Treatments were; T1 = early DI (8-21 d)+latter HI (22-35 d); T2 = early DI (8-28 d)+latter HI (29-35 d), T3 = early HI (8-21 d)+latter DI (22-35 d), T4 = early HI (8-28 d)+latter DI (29-35 d) and T5 = control (white light; WT) (8-35 d) at medium intensity (20 lux). Body weight (BW), weight gain (WG), water/feed intake and ratio, feed conversion ratios (FCR) were assessed. Common behaviours (15) were recorded by scan sampling method. Lameness, foot pad dermatitis, breast blisters, hock burning damage were assessed as welfare parameters. Fear reactions were tested using Tonic Immobility Test. Ocular and carcass evaluations were done. Meat and tibiae were analyzed for fat and bone ash respectively. Results: On 35 d, the highest BW ($2,155.72{\pm}176g$), WG ($1,967.78{\pm}174g$) were recorded by T2 compared to WT ($BW_{WT}=1,878.22{\pm}155$, $WG_{WT}=1,691.83{\pm}160$). But, application of RL, either DI, or HI during early/latter stage had no significant effect on FCR. Under HI, birds showed much higher active behaviours. DI encourages eating. Though LI changed from DI to HI, same trend could be seen even under HI. The highest leg strength ($218.5{\pm}120s$) was recorded by T2. The lowest leg strength ($64.58{\pm}33s$) and the highest ocular weight ($2.48{\pm}1g$) were recorded by T1. Significantly (p<0.05) the highest skin weight ($162.17{\pm}6g$) but the lowest fat% in meat ($13.03%{\pm}5%$) was recorded by T2. Conclusion: Early exposure to DI-RL up to 28 days followed by exposure to HI-RL is the most favorable lighting regimen for optimizing production, better welfare of broilers and improving health benefits of meat.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.7
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• pp.580-586
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• 2016

The ultra-long stroke engine was developed to generate greater power at lower speeds than previous designs to enhance the propulsion efficiency. The torsional exciting force, on the other hand, was increased significantly. Therefore, it is possible to control the torsional vibration of its shaft system equipped with the fuel efficient ultra-long stroke engine by adopting a damper although the torsional vibration could be controlled adequately by applying tuning and turning wheels on the engine previously. In this paper, the dynamic characteristics of a viscous-spring damper used to control the torsional vibration of the corresponding shaft system are reviewed and then examined to determine what vibration characteristics might be used to optimize the viscous-spring damper. In some cases, operators of eco-ships have recently experienced the problem of delayed RPM acceleration. It has been suggested that the proper measures for controlling the torsional vibration in the shaft system should involve adjusting the design parameters of its damper determined by the optimum damper design theory to avoid the fatigue damage of shafts.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.230-236
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• 2020

A trash screen is installed in front of the inflow channel of a drainage pumping station, sewage treatment plant, and a power plant to block floating contaminants. The bottleneck phenomenon, which decreases the water inflow, causes damage to the damper as a result of clogging in between the screen if string type obstacles are not removed. In this paper, the apron was removed, and the screen was expanded, to prevent breakage of the bottleneck phenomenon and string type obstacles. This was designed using an extended rake by adding an inner rake in between the screen interspace to remove the bottleneck phenomenon and string type obstacles. To design the inner rake that satisfies the allowable stresses of the existing damper rake, the experiment points were determined according to the experimental design method using the inner rake vertical length and the thickness of the reinforced section as parameters. The use of the ANSYS static structural module and statistical analysis tool R software gives the optimized shape according to the response surface method. The relative error between the response surface analysis results and the simulation results was 1.63% of the determined optimal design-point rake length of 210.2 mm and the reinforcement section thickness of 2 mm. Through empirical experiments, a test rake was constructed to the actual size, and approximately 97% of the bottleneck phenomenon and string type obstacles could be removed.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.31 no.3
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• pp.23-30
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• 2003

In this study, the various load cases by specified by the IEC61400-1 international specification and GL Regulations for the wind energy conversion system were considered, and a specific composite structure configuration which can effectively endure various loads was proposed. In order to evaluate the structure, the structural analysis for the composite wind turbine blade was performed using the finite element method(FEM). In the structural design, the acceptable configuration of blade structure was determined through the parametric studies, and the most dominant design parameters were confirmed. In the stress analysis using the FEM, it was confirmed that the blade structure was safe and stable for all the considerd load cases. Moreover the safety of the blade root joint with insert bolts, newly devised in this study, was checked against the design loads and also the fatigue loads. The fatigue life for operating more than 20 years was estimated by using the well-known S-N linear damage rule, the load spectrum and Spera's empirical equations. The full-scale static test was performed under the simulated aerodynamic loads. from the experimental results, it was found that the designed blade had the structural integrity. Furthermore the measured results were agreed with the analytical results such as deflections, strains, the mass and the radial center of gravity. The studied blade was successfully certified by an international institute, GL, of Germany.