• 한국동물위생학회지
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• 제25권1호
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• pp.45-52
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• 2002

The acute phase serum protein response is a well-known general indicator of inflammation, trauma or other pathological conditions and its relevance for the monitoring of the health status of domestic animals is being increasingly realized. The changes in serum protein composition which occur after tissue damage represent a part of the systemic response of the injured animals which is mediated by pro-inflammatory cytokines such as TNF-$\alpha$, IL-6 and IL-1. These responses play a vital role in containing the tissue damage and enhancing the processes of repair and resolution. From a clinical perspective, the assay of acute phase proteins can provide a method for detecting inflammation. In animals, the most sensitive acute phase proteins are haptoglogin, serum amyloid A and at-acid glycoprotein in response to inflammatory condition. The aim of this study was to assess the diagnostic value of the concentrations of serum amyloid A(SAA) and haptoglobin(HP) in serum of pigs infected with Aujeszky's disease virus(ADV). Fifty pigs infected with ADV and 5 normal pigs were used in this experiment. The mean serum concentration of Shh of pigs infected with ADV was 96.8 $\pm$ 7.1 $\mu\textrm{g}$/㎖(range, 36.0∼187.5 $\mu\textrm{g}$/㎖) and that of normal pigs was 42.9$\pm$3.3 $\mu\textrm{g}$/㎖(range, 17.3∼127.8 $\mu\textrm{g}$/㎖). The mean serum concentration of HP of pigs infected with ADV was 1,164.4 $\pm$ 96.9 $\mu\textrm{g}$/㎖ (range, 790.2∼l,769.2 $\mu\textrm{g}$/㎖) and that of normal pigs was 675.4 $\pm$ 56.3 $\mu\textrm{g}$/㎖ (range, 650.0-690.4 $\mu\textrm{g}$/㎖). The mean concentrations of SAA and HP in serum of pigs infected with ADV compared with those of normal pigs showed approximately a two-fold. It was concluded that the concentrations of Shh and HP in serum may proved to be diagnostic marker of Aujeszky's disease.

• Parasites, Hosts and Diseases
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• 제29권1호
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• pp.43-54
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• 1991

폐홉충(Paragonimus westermani) 초기 감염시의 숙주 면역 기전을 알아보기 위하여 폐흡충 피낭유충을 백서에 감염시켜 주별(주별)로 항혈청을 분리하고 등일 백서에서 복강 대식세포(homologous rat peritoneal macrophage)를 얻은 다음, 이들과 폐흡충 탈낭유충 및 숙주 조직 이행중인 유약충으로 effector system을 조작하여 폐흡충 유충에 대한 항체 의존성 대식세포 공격기전을 관찰하였다. 백서 복강 대식세포는 항혈청 출현 시에만 폐흡충 탈낭유충에 대한 세포부착 반응(cell adherence reaction)을 보였고 이 반응에는 보체가 관여하지 않았다. 폐흡충 감염 1주에서 8주까지의 백서 항혈청 중 2주째에 분리한 항쳔청 실험군에서 100%의 세포부착 반응을 나타내었고 사멸된 충체를 관찰할 수 있었으며, 세포부착 반응은 탈낭 유충기에서만 나타나는 반면 조직이행 유약충에서는 전혀 그 반응을 인정할 수 얼어 폐흡충 감염에 따른 항체의존성 숙주 세포 매개독성(antibodydependent cell·mediated cytotoxicity)은 발육단계 별 특이성을 보였다. 한편, 대식세포의 공격에 의하여 사멸된 폐흡충 탈낭유충의 형태학적 특징은 대식세포와 유충 사이에 형성되는 fuzzy material, tegumental syncytium 내의 미세구조의 변성 및 syncytium과 근육층을 연결하는 tubular tunnel의 형성 등이었다.

• 비파괴검사학회지
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• 제30권2호
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• pp.110-115
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• 2010

발전용 밸브 내부의 누설은 냉각 기능 상실 및 방사선물질 방출 동 안전계통의 성능 저하와 수많은 에너지 손실 등 발전소 운전에 막대한 손상 및 사고를 초래하게 된다. 본 논문은 신뢰성 높은 진단 방법 개발을 위하여 국내 원자력발전소 2차계통의 누설 발생 또는 내부 부품의 손상이 발생할 수 있는 밸브를 대상으로 현장시험 및 모의누설실험시의 적외선열화상 측정 실험을 수행함으로써 단일계측방식의 불확실성을 제거하고 향후 누설진단에 대한 확대 적용을 도모하고자 하였다. 발전소 현장시험 및 밸브 모의누설시험시의 밸브 누설 상태에 따른 적외선열화상 이미지 측정 실험을 통하여, 적외선열화상 측정 방법은 밸브 누설 상태의 과정을 신속하고 정밀하게 측정 가능하며 향후 많은 종류의 밸브 누설진단에 활용함으로써 누설에 따른 막대한 에너지 손실 및 사고 예방의 유용한 기법으로 확대 적용이 가능할 것으로 생각된다.

• Journal of Trauma and Injury
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• 제31권3호
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• pp.117-124
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• 2018

Purpose: This study was to analyze clinical and epidemiological characteristics of elderly patients who were admitted to the emergency department (ED) due to falls by separating male and female. Methods: We retrospectively analyzed the fall patients aged 65 years or older from the data of the in-depth surveillance study of injured patients visit to the ED under the supervision of the Korea Centers for Disease Control and Prevention (KCDC) from 2011 to 2016 by separating male and female. Results: A total of 361,588 elderly fall patients were analyzed and, among them, 14,429 (37.3%) were males and 24,208 (62.7%) were females. Male and female showed similar frequency of damage happening season. However, they showed falling accident mostly on winter. The time of injury occurrence is mostly from 12:00 to 18:00 with 4,949 (34.3%) male and 8,564 (35.4%) female. Most falls occurred in daily activities, accounting for 7,614 (52.8%) in males and 14,957 (61.8%) in females, respectively. Unintentional damage accounted for the most part and 7,395 (51.2%) of male and 15,343 (63.4%) of female were injured indoors. Head and neck were the most common site of injuring, with 8,392 (58.2%) in males and 7,851 (32.4%) in females. According to ED examination outcomes, most of the patients were discharged, while the majority of the hospitalized patients were admitted to the general patient room. Conclusions: The elderly falls occurred mostly from 12:00 to 18:00, during winter and to elderly women. Also, they happened unintentionally indoors in everyday life, mostly. Proved clinical, epidemiological characteristics from this research will be used as useful indicator at validity research of development of prevent program of falling accident for elderly people.

• 한국농림기상학회지
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• 제26권2호
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• pp.115-125
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• 2024

바람은 농업환경에 주요한 영향을 주는 기상요소이며, 강풍은 낙과, 시설물 파괴 등의 피해를 일으킨다. 본 연구는 LENS에 물리모델을 적용해서 농경지에 활용될 수 있는 저고도 풍속예측을 진행하였다. 물리모델은 LOG, POW가 사용되었고 지표 변수에 대해서는 환경부지표와 MODIS 지표를 따로 적용하였다. 농촌진흥청에서 운영하는 2022년도 3 m 고도의 바람 및 강풍 자료를 수집하고 검증을 진행하였고 결과를 산점도, 상관계수, RMSE, NRMSE, TS로 나타내었다. 풍속비교 4가지 방법의 결과에서 모델이 관측보다 더 크게 예측하고 있음을 확인할 수 있었다. 강풍 기준 값이 3 m s^-1 일 때, TS 가 약 0.65 정도로 나타났다. 결과는 RMSE와 NRMSE에서는 LOG_L, LOG_M, POW_L, POW_M 순으로 좋게 나타났고 상관계수와 TS에서는 역순으로 좋게 나타났다. 이러한 결과는 정해진 강풍 기준을 추가하여, 농경지 바람 및 강풍확률예측 연구에 도움이 될 것으로 기대된다.

• Journal of Ginseng Research
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• 제27권1호
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• pp.11-16
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• 2003

In this study, we investgated the effect of Red Ginseng (KRG) on liver damage induced by carbon tetrachloride (CTC) and galactosamine (GalN) in rats using indicator enzymes such as serum alanine/aspartate aminotransferases, sorbital dehydrogenase, lactate dehydrogenase, and ${\gamma}$-glutamyltransferase. Treatment of KRG restored these enzyme activities to near normal level compared to CTC or GalN treatment alone. Treatment of KRG also enhanced hepatic microsomal enzyme system, malondialdehyde formation, and depletion of reduced glutathione content, which were reduced by CTC or GalN. We also found that the decreased activities of glutathione S-transferase and glutathine reductase but not ${\gamma}$-glutamycysteine synthetase after KRG treatment restored to normal level. These results indicate that KRG has potent therapeutic activity against CTC- and GalN-induced hepatotoxicity in rat.

• Clinical and Experimental Pediatrics
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• 제60권9호
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• pp.302-306
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• 2017

Purpose: This study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children. Methods: This prospective observational study was conducted in the pediatric neurology ward of Soetomo Hospital. Cases of AES with ages ranging from 1 month to 12 years were included. Cases that were categorized as simple and complex febrile seizures constituted the non-AES group. Blood was collected for the measurement of NSE within 24 hours of hemodynamic stabilization. The median NSE values of both groups were compared by using the Mann-Whitney U test. All statistical analyses were performed with SPSS version 12 for Windows. Results: In the study period, 30 patients were enrolled. Glasgow Coma Scale mostly decreased in the AES group by about 40% in the level ${\leq}8$. All patients in the AES group suffered from status epilepticus and 46.67% of them had body temperature >$40^{\circ}C$. Most of the cases in the AES group had longer duration of stay in the hospital. The median serum NSE level in the AES group was 157.86 ng/mL, and this value was significantly higher than that of the non-AES group (10.96 ng/mL; P<0.05). Conclusion: AES cases showed higher levels of serum NSE. These results indicate that serum NSE is a good indicator of neuronal brain injury.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2005년도 춘계학술발표대회 논문집
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• pp.269-272
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• 2005

Nondestructive damage sensing and load transferring mechanism of Ni nanowire strands and multi-wall carbon nanotube (MWCNT)/epoxy composites were investigated using electro-micromechanical techniques. MWCNT composite was especially prepared for high volume contents, 50 vol % of reinforcement. Electro-micromechanical techniques were applied to measure apparent modulus and contact resistance of Ni nanocomposites with their alignment and different diameters, and adding contents. Applied cyclic load affected on apparent modulus and electrical properties on nanocomposites due to various inherent properties of each CNMs. Contact resistivity on humidity sensing was a good indicator for monitoring as for multifunctional applications. Further study on actuation as well as sensing will be investigated for the following work continuously.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 추계학술대회논문집
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• pp.1272-1275
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• 2007

The HDD (hard disk drive) using Load/Unload (L/UL) technology includes the benefits which are increased areal density, reduced power consumption and improved shock resistance than those of contact-start-stop (CSS). Dynamic L/UL has been widely used in portable hard disk drive and will become the key technology for developing the small form factor hard disk drive. Main design objectives of the L/UL mechanisms are no slider-disk contact or no media damage even with contact during L/UL, and a smooth and short load and unload process. In this paper, we focus on state matrix, pitch static attitude (PSA), roll static attitude (RSA), loading/unloading contour (LC/ULC), impact force and contact. Stability of slider is mainly determined by PSA and RSA. State matrix by PSA and RSA is also important indicator. Therefore we analyze state matrix of SFF HDD suspension through the LC/ULC.

• 한국압력기기공학회 논문집
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• 제10권1호
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• pp.37-43
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• 2014

Nuclear power plants(NPPs) are consisted of power production functions and safety functions preventing leakage of radiation. Operators working in NPPs shall maintain these functions during an operation period through various activities such as improvement & modification, corrective maintenance, preventive maintenance and surveillance test. According to the performance of these work activities, there are configuration changes in NPPs systems. Its changes cause the increase of safety risks(CDF) and plant trip risks. Recently, the importance of risk management is increasing gradually in the operation process of NPPs. Therefore, this paper presents the work management methods using the various risk monitoring systems during power operation and overhaul period. Also this paper suggests the optimum application ways of risk systems for work management.