• Title/Summary/Keyword: Dae-young

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A Clinical study carried out common acupuncture therapy and Bee-Venom Acupuncture on HNP of L-spine (봉독약침병행치료(峰毒藥鍼竝行治療)한 요추간판탈출증환자(腰椎間板脫出症患者)의 임상고찰(臨床考察))

  • Bae, Eun-Jeong;Cho, Hyun-Yeul;Jin, Jae-Do;Shin, Min-Kyu;Han, Sang-Gyun;Yang, Gi-Young;Hwang, Kyu-Jung;Shin, Young-Il;Lee, Hyun;Lee, Byung-Ryul
    • Journal of Acupuncture Research
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    • v.19 no.1
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    • pp.54-64
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    • 2002

  • Objective : The one of the main cause in back pain & sciatica is HNP of L-spine. This study is for taking data for the clinical application of Bee-Venom Acupuncture on HNP of L-spine. Methods : This clinical study was carried out 24 patients with HNP of L-spine, who had been admitted from March, 2001 to November, 2001. We devided the patients into two groups; One was an experimental group, treated by 2 methods-common acupuncture therapy and Bee-Venom Acupuncture. The other was an control group, treated only by common acupuncture therapy. Results and Conclusion : In an experimental group, there were 4 excellent cases (33.33%) and 5 good cases(41.67%). In an control group, there were 2 excellent cases (16.67%) and 5 good cases (41.67%). We thought that it needed to prove effects of Bee- Venom Acupuncture for efficient application by more clinical data from now.

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Identification of domesticated silkworm varieties using single nucleotide polymorphisms detected from mitochondrial genomes

  • Park, Jong Woo;Park, Jeong Sun;Jeong, Chan Young;Kang, Sang Kuk;Kim, Seong-Wan;Kim, Nam-Suk;Kim, Kee Young;Kim, Iksoo
    • International Journal of Industrial Entomology and Biomaterials
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    • v.45 no.1
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    • pp.29-34
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    • 2022

  • Silkworms have recently attracted attention as healthy functional foods. Different varieties of silkworms have functional differences; thus, there is an emerging need for variety identification. In this study, we sequenced complete mitochondrial genomes (mitogenomes) of ten government-recommended silkworm varieties (BaekHwang, BaekOk, DaeBaek, DaeBak, DaeHwang, GoldenSilk, HanSaeng, JooHwang, KumKang, and KumOk). Comparison of these sequences allowed us to select the single nucleotide polymorphisms (SNPs) in 34 sites that are specific to six silkworm varieties: 13 in DaeBak, 8 in GoldenSilk, 9 in KumKang, 2 in BaekHwang, 1 in BaekOk, and 1 in DaeHwang. Among these each one SNP per variety was amplified by preparing variety-specific primers and then using tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR). As a result, it was possible to identify these six varieties among the ten silkworm varieties, evidencing that SNPs developed from mitogenomes are useful marker for the discrimination of genetically closer silkworm varieties.

  • https://doi.org/10.7852/ijie.2022.45.1.29 인용 PDF KSCI

The Neuroprotective Effects of InSamYangYoung-tang(Renshenyangrongtang) on Aβ-induced Damages in Mice (인삼양영탕(人蔘養榮湯)이 Aβ를 처리한 PC12 세포와 생쥐의 손상 뇌신경조직에 미치는 영향)

  • Jang, Young-Joo;Jung, In-Chul;Lee, Sang-Ryong
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.1
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    • pp.109-124
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    • 2010

  • Objectives: This experiment was designed to investigate the effect of the InSamYangYoung-tang(Renshenyangrongtang) extract on $A{\beta}$-induced AD model. Methods: The effects of the InSamYangYoung-tang(Renshenyangrongtang) extract on neural damages of cultured PC12 cells induced by $A{\beta}$ were investigated. The effects of the InSamYangYoung-tang(Renshenyangrongtang) extract on neural damages of hippocampal and cortical neurons in the mouse induced by $\beta$-amyloid were investigated. Results: 1. $A{\beta}$ treatment into neuronal cells activated cell death pathway when analyzed by MTT assay and by histological analysis. Then InSamYangYoung-tang(Renshenyangrongtang) treatment improved cell survival to a similar level as in normal group. 2. $A{\beta}$ treatment increased caspase 3 protein levels but decreased phospho-Erk1/2 in neuronal cells. InSamYangYoung-tang(Renshenyangrongtang) treatment reversed the production levels of two proteins close to those in normal group. 3. $A{\beta}$ treatment induced the atrophy of neuronal cells in terms of neuronal processes and cell body shrinkage, but InSamYangYoung-tang(Renshenyangrongtang) greatly improved their morphology. 4. Neuroprotective activity, as observed in InSamYangYoung-tang(Renshenyangrongtang)-treated groups, was similarly observed in cells treated with galantamine which was used as a positive control. Moreover, overall recovery pattern by InSamYangYoung-tang(Renshenyangrongtang) was similar between cultured PC12 cells and in vivo hippocampal and cerebral cortical neurons in the mouse brain. Conclusions: This experiment shows that the InSamYangYoung-tang(Renshenyangrongtang) may play a protective role in neural tissues damaged by cytotoxic substances. Since neuronal damage seen in degenerative brains such as AD are largely unknown, the current data may provide possible insight into therapeutic strategies for AD treatments. InSamYangYoung-tang(Renshenyangrongtang) might be effective for the treatment of AD. Investigation into the clinical use of the InSamYangYoung-tang(Renshenyangrongtang) for AD is suggested for future research.

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