• International journal of steel structures
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• v.18 no.5
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• pp.1560-1576
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• 2018

With the aim to provide an efficient platform for the elastic-plastic analysis of steel structures, reinforced concrete (RC) structures and steel-concrete composite structures, a program iFiberLUT based on the fiber model was developed within the framework of ABAQUS. This program contains an ABAQUS Fiber Generator which can automatically divide the beam and column cross sections into fiber sections, and a material library which includes several concrete and steel uniaxial material models. The range of applications of iFiberLUT is introduced and its feasibility is verified through previously reported test data of individual structural members as well as planar steel frames, RC frames and composite frames subjected to various loadings. The simulation results indicate that the developed program is able to achieve high calculation accuracy and favorable convergence within a wide range of applications.

• Journal of Korean Medical classics
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• v.31 no.2
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• pp.83-103
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• 2018

Objectives: The Qing Dynasty experienced a development in Yunqi even greater than in the Ming Dynasty. Popularization and universalization of Yunqi theory led to many books on the subject published, especially with weights on Warm Heat Disease and Pestilence, also giving birth to new Yunqi theories. A study into this development has a great significance in the study of the traditional medicine in Qing. Methods: The paper studies the Yunqi books published in the Qing dynasty to find out the unique characters of those books. To understand the direction which the Yunqi theory in the Qing period took, the paper also reviewed the positions of different groups, those who were favorable, those who compromised, and those who were unfavorable. Results: Four directions were taken by the study of Yunqi in the Qing period. First is the systemic study and composition of Neijing's chapter of Yunqi. This direction was taken by Liumaoxiu's NeiJingYunQiBingShi) and $N{\grave{e}}ijingyunqibiao$, Xuefuchen's Suwenyunqitushuo, Zhuenhua's Suwenyunqiqianshuo, an unknown person's Su wen yunqi chao, Weigeliu's Neijingqihuapian. The second direction is the study of Yunqi in relation with the Warm Heat Disease and Pestilence, which was taken by Mayin lin's Wuyunliuqiwenyifayuan, Lumaoxiu's Suwenyipianbìngshi, Litianchi's Shiyiwenbingqìyunzhengyan lun, and Wangxun's Cihangsanyuanfujifang. The third direction deals with a new Yunqi theory. The Fourthis the explanation of Yunqi in the form of Songs, which was taken by Wuqian's Yunqiyaojue, and Wengzao's Yunqiyaojue. Conclusions: Ludanchen published Yunqibian, and explained that Haizichouyinmaochen, which is the eclipse's south latitude, becomes Nanzheng, and Southern government, which is the eclipse's north latitude, becomes Northern government. Lumaoxiu revealed that the Liuqidasitian, founded by Wangpuzhuang, his great grandfather on the mother's side, is in alignment with the theory of Dashitian, used by Liushozhen, Lidongyuan, Zhudanxi, and Zhangjingyue. The representative figure in the favorable view of Yunqi in the Qing period is Wuyang, that of those who compromised is Fengzhaozhang, and that of opposition is Zhangzhuo.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.1
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• pp.504-511
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• 2020

This paper studies the operational efficiency of the new sesame variety "da u" farmed by the Rural Development Administration. In the survey area--Gyeonggi-do Province, where sesame cultivation was the most intensive. Thirty farmers were surveyed by rural enterprises in the Yangpyeng area where 'da u' was planted. The efficiency of the operation was analyzed by studying the data of 30 farmers. In order to analyze the operational efficiency of the farmers, this survey used the DEA model for analysis in order to determine the technical efficiency of farmers. The result shows that the DEA technical efficiencies of most farmers are efficient, and only 6 farmers are inefficient. The reason for the inefficiency is the high cost of input factors. To analyze the determinants of efficiency through the Tobit model, reducing the pesticides and general fertilizers led to increased technical efficiency. This is inefficient use of pesticides and general fertilizers relative to the output factor, and efficient methods should reduce the cost issues.

• Food Science of Animal Resources
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• v.37 no.5
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• pp.764-772
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• 2017

Fertilized hen eggs are rich in a variety of bioactive ingredients. In this study, we aimed to obtain an antioxidant protein from fertilized eggs and the radical scavenging abilities on 1, 1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical (${\bullet}OH$), superoxide anion ($O^{2-}{\bullet}$) were used to evaluate the antioxidant activity of the purified protein. During 20 d of incubation, the radical scavenging ability of protein extracted from fertilized eggs exhibited significantly differences and the protein on day 16 showed higher antioxidant capacity. Based on this, the antioxidant protein of the samples on day 16 were isolated for the follow-up study. With a molecular weight 43.22 kDa, the antioxidant protein was purified by Diethylaminoethyl cellulose -52 (DEAE-52) column and Sephadex G-100. The LC-MS analysis showed that the purified protein molecular weight was 43.22 kDa, named D2-S. The sequence of amino acids was highly similar to ovalbumin and the coverage reached to 84%. The purified protein showed a radical scavenging rate of $52.34{\pm}3.27%$ on DPPH and $63.49{\pm}0.25%$ on ${\bullet}OH$, respectively. Furthermore, the C-terminal amino acid sequence was NAVLFFGRCVSP, which was consistent with the sequence of ovabumin. These results here indicated that purified protein may be a potential resource as a natural antioxidant.

• Journal of Korean Medical classics
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• v.13 no.2 s.17
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• pp.86-95
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• 2000

Following is the result through translating. studying, and analyzing San Zhi Shan(三指禪), the book worked by Zhou Xue Ting(周學霆). 1. The chapter of Mai Xue Yuan Liu(脈學源流) explains the Xiang Shu Xue(象數學) viewpoint, the part that pulse is based on Lu guan(律管). 2. The chapter of Liu Bu Mai Jie(六部脈解) explains that emphasizing Shen(神) through understanding the shape of pulse(脈象) is more important than the locating the area of the shape of pulse(脈象). 3. The chapter of Zuo Xin Tan Zhong Can Dan Shen Xiao Chang You Fei Xiang Zhong Pi Wei Ming Da Chang Bian(左心膽中肝膽腎小腸 右肺胸中脾胃命大腸辨) exhibits the different view about the position of pulse from Li Shi Zhen(李時珍)'s. the chapter in which Zhou(周) arranges Heart{\cdot}Small\;Intestine{\cdot}Liver{\cdot}Gall\;Bladder{\cdot}Kidneys{\cdot}and$ Bladcler(心 小腸 肝 膽 腎 膀胱) in left hand and $Lungs{\cdot}Large{\cdot}Intestine{\cdot}Spleen{\cdot}Stomach{\cdot}Kidney{\cdot}and$ The gate of Vitality(肺 大腸 脾 胃 腎 命門) in right hand. From the above results, I'm sure that San Zhi Shan(三指禪)which has headed down to descendants as the special book about the study of pulse has developed the theory of pulse. Therefore I expect that the more profound study about this will be going on.

• BMB Reports
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• v.41 no.11
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• pp.765-770
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• 2008

Undesirable hyperpigmentation that can arise from increased melanocyte activity may be alleviated by targeting active melanocytes for apoptosis. The role of Stathmin 1 as an important regulator of microtubule dynamics is well documented. The current study examined the potential of Stathmin 1-targeting strategies in eliminating active melanocytes. A vector to overexpress Stathmin 1 and vectors to express three distinct small hairpin RNAs to knockdown Stathmin 1 expression in normal melanocytes were produced and in cell cultures acted accordingly. Both overexpression and knockdown of Stathmin 1 led to a marked increase in melanocyte apoptosis, as indicated by the accumulation of apoptotic cells and increased levels of cleaved caspase-3. Both up- and down-regulation of Stathmin 1 expression inhibited the activity of differentiated melanocytes, as indicated by decreases in both melanin production and tyrosinase activity. Taken together, these results indicate that hyperactive melanocytes can be inhibited by altering Stathmin 1 expression.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4441-4444
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• 2012

Background: Polymorphisms of the Taq I gene have been associated with prostate cancer risk. Methods:We applied a fixed-effects model to combine odds ratios (ORs) and 95% confidence intervals (95% CI). The Egger's test was carried out to evaluate potential publication bias. Results: A total of 10 case-control studies enrolling 1,141 prostate cancer patients and 1,685 controls were included in this meta-analysis. Compared with the T allele, the OR for the C allele was 0.81 (0.70-0.94). The ORs for CT and CC+CT genotypes were 0.86 (0.74-1.01) and 0.84 (0.73-0.97) compared to wide type genotype (homozygote TT). Conclusions: The present meta-analysis suggests that the TF gene Taq I polymorphism may reduce the prostate cancer risk in Asian populations.

• Journal of Microbiology and Biotechnology
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• v.30 no.3
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• pp.368-377
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• 2020

Enterotoxigenic Bacteroides fragilis (ETBF) is the main pathogen causing severe inflammatory diseases and colorectal cancer. Its biofilm plays a key role in the development of colorectal cancer. The objective of this study was to determine the antagonistic effects of cell-free supernatants (CFS) derived from Clostridium butyricum against the growth and biofilm of ETBF. Our data showed that C. butyricum CFS inhibited the growth of B. fragilis in planktonic culture. In addition, C. butyricum CFS exhibited an antibiofilm effect by inhibiting biofilm development, disassembling preformed biofilms and reducing the metabolic activity of cells in biofilms. Using confocal laser scanning microscopy, we found that C. butyricum CFS significantly suppressed the proteins and extracellular nucleic acids among the basic biofilm components. Furthermore, C. butyricum CFS significantly downregulated the expression of virulence- and efflux pump-related genes including ompA and bmeB3 in B. fragilis. Our findings suggest that C. butyricum can be used as biotherapeutic agent by inhibiting the growth and biofilm of ETBF.

• International Journal of Aeronautical and Space Sciences
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• v.17 no.1
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• pp.29-36
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• 2016

Tensairity girder is a light weight inflatable fabric structural concept which can be used in road emergency transportation. It uses low pressure air to stabilize compression elements against buckling. With the purpose of obtaining the comprehensive target of minimum deflection and weight under ultimate load, the cross-section and the inner pressure of tensairity girder was optimized in this paper. The Variable Complexity Modeling (VCM) method was used in this paper combining the Kriging approximate method with the Finite Element Analysis (FEA) method, which was implemented by ABAQUS. In the Kriging method, the sample points of the surrogate model were outlined by Design of Experiment (DOE) technique based on Optimal Latin Hypercube. The optimization framework was constructed in iSIGHT with a global optimization method, Multi-Island Genetic Algorithm (MIGA), followed by a local optimization method, Sequential Quadratic Program (SQP). The result of the optimization gives a prominent conceptual design of the tensairity girder, which approves the solution architecture of VCM is feasible and efficient. Furthermore, a useful trend of sensitivity between optimization variables and responses was performed to guide future design. It was proved that the inner pressure is the key parameter to balance the maximum Von Mises stress and deflection on tensairity girder, and the parameters of cross section impact the mass of tensairity girder obviously.

• Smart Structures and Systems
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• v.14 no.5
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• pp.765-784
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• 2014

In comparison with conventional shape memory actuated structures, antagonistic shape memory alloy (SMA) actuators permits a fully reversible two-way response and higher response frequency. However, excessive internal stress could adversely reduce the stroke of the actuators under repeated use. The two-way shape memory effect might further decrease the range of the recovered strain under actuation of an antagonistic SMA actuator unless additional components (e.g., spring and stopper) are added to regain the overall actuation capability. In this paper, the performance of all four possible types of SMA actuation schemes is investigated in detail with emphasis on five key properties: recovered strain, cyclic degradation, response frequency, self-sensing control accuracy, and controllable maximum output. The testing parameters are chosen based on the maximization of recovered strain. Three types of these actuators are antagonistic SMA actuators, which drive with two active SMA wires in two directions. The antagonistic SMA actuator with an additional pair of springs exhibits wider displacement range, more stable performance under reuse, and faster response, although accurate control cannot be maintained under force interference. With two additional stoppers to prevent the over stretch of the spring, the results showed that the proposed structure could achieve significant improvement on all five properties. It can be concluded that, the last type actuator scheme with additional spring and stopper provide much better applicability than the other three in most conditions. The results of the performance analysis of all four SMA actuators could provide a solid basis for the practical design of SMA actuators.