• Imaging Science in Dentistry
• /
• v.49 no.2
• /
• pp.171-176
• /
• 2019

The available methods for veneer evaluation are limited to clinical and radiographic examinations, which may not allow the appropriate identification of failure. In this report, we demonstrate the use of optical coherence tomography (OCT) as a noninvasive diagnostic and follow-up method to evaluate gingival recovery and the adhesive interface in aesthetic oral rehabilitation involving periodontal plastic surgery and ceramic laminate veneers. OCT was efficient for evaluating both soft and hard tissues, as well as the quality of the adhesive interface. In conclusion, OCT was found to be a promising approach for the professional evaluation of aesthetic oral rehabilitation, as it was capable of generating images that enabled the analysis of gingival recovery and the adhesive interface.

• International Area Studies Review
• /
• v.18 no.3
• /
• pp.175-201
• /
• 2014

This paper analyses the effect of R&D investment on local economies. R&D investment contributes to the regional local economy by increasing employment and production activity of the investees. The investees may end up with increased productivity, sales and employment. At the regional R&D level, the central government R&D fund and firm self R&D budget will be the source of R&D investment. Further positive effects are inter-related with local industries. This study carried out an empirical analysis on the effect of R&D investment on local economies using Korean panel data after comparing international literatures. The dynamic panel estimator is used to estimate an autoregressive model with lagged dependent variable. Using the Da Silva method, mixed variance-component moving-average error process is estimated and selected. R&D investment is very important factor to improve the productivity of a region and the size of the effect is dependent on the time periods within the Korean economic history.

• Computers and Concrete
• /
• v.17 no.1
• /
• pp.141-156
• /
• 2016

The search for new structural systems capable of associating performance and safety requires deeper knowledge regarding the mechanical behavior of structures subject to different loading conditions. The Strut-and-Tie Model is commonly used to structurally designing some reinforced concrete elements and for the regions where geometrical modifications and stress concentrations are observed, called "regions D". This method allows a better structural behavior representation for strength mechanisms in the concrete structures. Nonetheless, the topological model choice depends on the designer's experience regarding compatibility between internal flux of loads, geometry and boundary/initial conditions. Thus, there is some difficulty in its applications, once the model conception presents some uncertainty. In this context, the present work aims to apply the Strut-and-Tie Model to nonlinear structural elements together with a topological optimization method. The topological optimization method adopted considers the progressive stiffness reduction of finite elements with low stress values. The analyses performed could help the structural designer to better understand structural conceptions, guaranteeing the safety and the reliability in the solution of complex problems involving structural concrete.

• Steel and Composite Structures
• /
• v.4 no.2
• /
• pp.77-94
• /
• 2004

Steel beam-to-column joints are often subjected to a combination of bending and axial forces. The level of axial forces in the joint may be significant, typical of pitched-roof portal frames, sway frames or frames with incomplete floors. Current specifications for steel joints do not take into account the presence of axial forces (tension and/or compression) in the joints. A single empirical limitation of 10% of the beam's plastic axial capacity is the only enforced provision in Annex J of Eurocode 3. The objective of the present paper is to describe some experimental and numerical work carried out at the University of Coimbra to try to extend the philosophy of the component method to deal with the combined action bending moment and axial force.

• International Journal of Fluid Machinery and Systems
• /
• v.8 no.1
• /
• pp.55-62
• /
• 2015

This study aims to present a hydraulic transitory study as MOC applications for solving the Saint-Venant equations in two case studies: 1) in a penstock of a small hydropower system as a simple pipeline in the case of valve-closure in the downstream boundary with a reservoir in the upstream boundary; and 2) for discharge propagation into a channel by velocity and depth of the flow channel along space evaluation. The proposed methodology by Chaudry [5] concerning the development of hydrodynamic models was used. The obtained results for first and second case study has been confirmed that MOC numerical approach is useful for several engineering purposes, including cases of hydraulic transients and discharge propagation in hydraulic systems.

• Steel and Composite Structures
• /
• v.1 no.2
• /
• pp.245-268
• /
• 2001

The analysis of steel-concrete composite joints presents some particular aspects that increase their complexity when compared to bare steel joints. In particular, the influence of slab reinforcement and column concrete encasement clearly change the moment-rotation response of the joint. Starting from an energy approach developed in the context of steel joints, an extension to composite joints is presented in this paper that is able to provide closed-form analytical solutions. In addition, the possibility of tri-linear or non-linear component behaviour is also incorporated in the model, enabling adequate treatment of the influence of cracked concrete in tension and the softening response of the column web in compression. This methodology is validated through comparison with experimental tests carried out at the University of Coimbra.

• Applied Microscopy
• /
• v.51
• /
• pp.6.1-6.9
• /
• 2021

Histopathology is a well-established standard diagnosis employed for the majority of malignancies, including breast cancer. Nevertheless, despite training and standardization, it is considered operator-dependent and errors are still a concern. Fractal dimension analysis is a computational image processing technique that allows assessing the degree of complexity in patterns. We aimed here at providing a robust and easily attainable method for introducing computer-assisted techniques to histopathology laboratories. Slides from two databases were used: A) Breast Cancer Histopathological; and B) Grand Challenge on Breast Cancer Histology. Set A contained 2480 images from 24 patients with benign alterations, and 5429 images from 58 patients with breast cancer. Set B comprised 100 images of each type: normal tissue, benign alterations, in situ carcinoma, and invasive carcinoma. All images were analyzed with the FracLac algorithm in the ImageJ computational environment to yield the box count fractal dimension (Db) results. Images on set A on 40x magnification were statistically different (p = 0.0003), whereas images on 400x did not present differences in their means. On set B, the mean Db values presented promising statistical differences when comparing. Normal and/or benign images to in situ and/or invasive carcinoma (all p < 0.0001). Interestingly, there was no difference when comparing normal tissue to benign alterations. These data corroborate with previous work in which fractal analysis allowed differentiating malignancies. Computer-aided diagnosis algorithms may beneficiate from using Db data; specific Db cut-off values may yield ~ 99% specificity in diagnosing breast cancer. Furthermore, the fact that it allows assessing tissue complexity, this tool may be used to understand the progression of the histological alterations in cancer.

• Restorative Dentistry and Endodontics
• /
• v.46 no.1
• /
• pp.11.1-11.11
• /
• 2021

Objectives: The aim of this study was to compare smear layer removal by conventional application (CA), passive ultrasonic irrigation (PUI), EasyClean (EC), and XP-Endo Finisher (XPF), using 17% ethylenediaminetetraacetic acid (EDTA) after chemomechanical preparation, as evaluated with scanning electron microscopy (SEM). Materials and Methods: Forty-five single-rooted human mandibular premolars were selected for this study. After chemomechanical preparation, the teeth were randomly divided into 5 groups according to the protocol for smear layer removal, as follows: G1 (control): CA of distilled water; G2 (CA): CA of 17% EDTA; G3 (PUI): 17% EDTA activated by PUI; G4 (EC): 17% EDTA activated by EC; and G5 (XPF): 17% EDTA activated by XPF. SEM images (×1,000) were obtained from each root third and scored by 3 examiners. Data were evaluated using the Kruskal-Wallis and Dunn tests (p < 0.05). Results: In the apical third, there were no statistically significant differences among the groups (p > 0.05). In the cervical and middle thirds, the experimental groups performed better than the control group (p < 0.05); however, G2 presented better results than G3, G4, and G5 (p < 0.05), which showed no differences among one another (p > 0.05). Conclusions: No irrigation method was able to completely remove the smear layer, especially in the apical third. Using CA for the chelating solution performed better than any form of activation.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.10
• /
• pp.4769-4774
• /
• 2016

Objective: To analyze the survival of elderly patients with breast cancer according to the type of treatment used. Methods: A cohort study of women aged 80 or over with breast cancer registered with the Brazilian National Cancer Institute (Instituto Nacional do $C{\hat{a}}ncer$ - INCA) between 2008 and 2009 was conducted. Prognosis was analyzed according to the cancer treatment performed: surgery, radiotherapy, or hormone therapy. Analysis of the overall 5-year survival rate was performed using the Kaplan - Meier method, and comparisons of curves were undertaken using the log-rank test. For multiple regression analysis, Cox regression was used, adjusting for age and clinical stage, considering values of p < 0.05 as significant. Data were all analyzed using the statistical package SPSS version 20. Results: 70 women with a mean age of $84.0{\pm}3.7years$ at diagnosis participated in the study. The median follow-up time was 37.1 months (range 0.5-75.5), and 31 deaths (44.3%) occurred during this time. The median survival time was 51.2 months (95% CI, 44.9-57.4), higher in those who underwent surgery (p = 0.012) and those who had hormone therapy (p=0.001). Treatment with surgery reduced the risk of death by 61.7% (HR 0.3; 95% CI, 0.1-0.6; p = 0.001) when adjusted for clinical stage and age at diagnosis. However, there was no significant benefit from radiotherapy (HR 1.2; 95% CI, 0.5-2.5; p = 0.694). Conclusion: Treatment with surgery and hormone therapy increased the survival of our Brazilian patients with breast cancer aged 80 or over.

• Steel and Composite Structures
• /
• v.9 no.1
• /
• pp.39-58
• /
• 2009

Composite joints, considering the composite action of steel and concrete, exhibit, in general, high strength and high ductility. As a consequence, the use of this type of joint has been increasing in many countries, especially in those that are located in earthquake-prone regions. In this paper, a hysteretic model with pinching is presented that is able to reproduce the cyclic response of steel and composite joints. Secondly, the computer implementation and adaptation of the model in a spring element within the computer code Seismosoft is described. The model is subsequently calibrated using a series of experimental test results for composite joints subjected to cyclic loading. Finally, typical parameters for the various joint configurations are proposed.