• 약학회지
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• 제57권2호
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• pp.119-124
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• 2013

The aim of this present study was to investigate the antifungal effect of tanshinones isolated from Salvia miltiorrhiza against Candida ablicans, a polymorphic fungus. For the work, tanshinone IIA (TSN), cryptotanshinone (CTS), and dihydrotanshinone I (DTS) were chosen. Initially, their antifungal effect was analyzed by in-vitro susceptibility test. Data from the susceptibility test showed that while all of these three compounds had antifungal activity, DTS was the most potent. At $100{\mu}g$ DTS/ml, there was about 80% CFU (colony forming unit) reduction as compared to DTS-untreated C. albicans yeast cells (P<0.05). Thus, DTS was selected to determine its antifungal activity in a murine model of disseminated candidiasis due to C. albicans. Results showed that DTS enhanced resistance of mice against disseminated candidiasis. During the entire period of 30-day observation, 60% of DTS-given mice groups survived whereas control animals all died within 14 days (P<0.05). Moreover, DTS inhibited the hyphal production, one of the virulence factors of this fungus, from the blastoconidial form of the fungus. Therefore, the tanshinone appears to have antifungal activity specific for C. albicans infection, which could possibly be mediated by the blockage of hyphal production.

• KSBB Journal
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• 제26권5호
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• pp.433-438
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• 2011

These studies were conducted to investigate the alcohol degradation effects of the extract of herbal composition (DTS20) containing Viscum album L., Lycium chinense L., Inonotus obliquus and Acanthopanax senticosus H., on the alcohol administered mice. To investigate anti-hangover effect, alcohol and alcohol dehydrogensae (ADH) concentration of blood were measured after oral administration of ethanol. The administration of DTS20 (200-500 mg/kg) had beneficial actions toward alcohol degradation in acute alcohol treated mice model. The oral administration of DTS20 showed decreased gastric mucous membrane damage produced in ethanol treated mice. In addition, intraperitoneal administration of DTS20 showed anti-inflammatory effects in inhibition tests of vascular permeability produced by acetic acid. DTS20 also reduced the concentration of nitric oxide (NO), tumor necrosis factor (TNF)-${\alpha}$ in macrophages that were activated by LPS. These results demonstrate that DTS20 possesses potential to stimulate the alcohol degradation and inhibit the inflammatory effects in mice.

• 한국화재소방학회논문지
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• 제30권4호
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• pp.27-38
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• 2016

본 논문은 현재 국외기술에 의존하고 있는 광센서 선형감지기를 이용한 화재감지시스템인 분산온도감지(DTS) 시스템을 국산화 기술로 개발하기 위한 연구이다. 이에 본 연구에서는 광섬유 내에서 발생되는 빛의 역산란광 중 온도감지에 주로 사용되는 라만산란광의 전기적 신호파형을 오실로스코프를 이용하여 분석하였다. 측정결과 Stokes 신호파형은 온도가 상승해도 변화량이 거의 없었으나, 온도에 민감한 anti-Stokes 신호파형은 상대적으로 그 값이 증가하는 것을 확인할 수 있었다. 그리고 라만산란광을 이용하여 화재를 감지할 수 있는 광중계기 및 광수신기로 구성된 광센서 선형 화재감지시스템인 K-DTS 시스템을 개발하였다. 개발된 K-DTS 시스템에 대하여 차동식 및 정온식 감도시험기를 이용하여 차동식 및 정온식 감지기로서의 감도시험을 진행해 본 결과 형식승인 기준을 만족하고 있는 것을 확인할 수 있었다. 또한, 개발된 K-DTS 시스템의 성능평가를 위해 국외에서 수입되어 가장 많이 사용되고 있는 S-DTS 시스템과 성능비교실험을 진행하였다. 모형터널을 이용한 성능실험결과 화재감지위치 및 화재온도 측정에서 유사한 성능을 나타내는 것을 확인할 수 있었다.

• 한국환경과학회지
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• 제24권11호
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• pp.1547-1550
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• 2015

Fuji apple variety introduced in Japan has excellent storage quality and good taste so it is most commonly cultivated in the Korean Peninsula. Accurate prediction of harvest maturity allows farmers to more efficiently manage their farm, such as working time, fruit storage, market shipment and labor distribution so it is very important. This study was carried out to predict the harvest maturity of 'Fuji' apple using DTS (Days Transformed to Standard temperature) model based on the Arrhenius law in the Gunwi province of the South Korea. Input data are daily average temperature and apple harvest maturity. Predicted the harvest maturity of Fuji apple after estimating the optimal parameters by using the Nelder-Mead method. The differences of observed and predicted harvest maturity day are approximately 1 to 4 days and the RMSE is 2.9.

• International Journal of Contents
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• 제8권2호
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• pp.23-27
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• 2012

The successful use of digital textbooks (DTs) in schools requires the development of various teaching and learning methods that are appropriate for DTs. However, recent DT studies have focused mainly on the implementation of DT features and formats. The objective of this study was to investigate a problem-based learning instructional model appropriate to DTs and to present the experimental results using the problem-based DT to demonstrate its educational effectiveness. Two learning-achievements tests were conducted to analyze the learning experience and effectiveness of the problem-based DT after it had been used in a high school for a certain period. The experimental results indicated that the students who used the DT, especially lower-level students, exhibited improved problem-solving ability and demonstrated a better practical understanding of the subject than students who used printed textbooks.

• 지적과 국토정보
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• 제51권1호
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• pp.5-22
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• 2021

디지털 트윈 국토는 한국판 뉴딜 정책의 일환으로 추진 중인 국가 프로젝트이나 이에 대한 표준이나 기술 기준 등은 마련되어 있지 않은 상태이다. 이러한 배경에서 본 연구는 디지털 트윈 국토의 상호 운용성 확보를 위한 공간정보 표준 기반의 참조 모델과 데이터 모델 구축 방안을 제시하는데 목적이 있다. 이를 위해 디지털 트윈에 관한 국제 표준화 동향을 검토하고 주요 시사점을 도출하였다. 그리고 디지털 트윈 국토에 대한 정의, 도메인별 특징을 도출하는 등 디지털 트윈 국토에 대한 개념을 정립하였다. 이러한 개념을 바탕으로 RM-ODP를 이용한 디지털 트윈 국토 참조 모델 구축 방안과 3단계 디지털 트윈 국토 데이터 모델 체계를 제안하였다. 또한 데이터 모델의 효율적 관리를 위한 모델 레지스트리 구축 방안을 제안하였다. 본 연구에서 제안한 정책 방안은 향후 디지털 트윈 국토 표준 체계 구축의 방향성을 확립하는데 기여할 것으로 판단된다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 추계학술대회 논문집 전력기술부문
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• pp.30-34
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• 2005

Due to old Toshiba EMS's database size limit and hardware old aging, KPX(Korea Power Exchange) had introduced New EMS from AREVA(old ALSTOM) in July 2002. After then KPX had committed many man power and time to normalize EMS NA(Network Analysis) functions for using real power system. At initial stage, to normalize State Estimator which is the backbone of all other NA functions and DTS(Dispatcher Training Simulator}, KPX had corrected numerous topology errors, network model errors, non-scanned and wrongly scanned SCADA measured errors. After SE function study, running test and tuning, State Estimator could finally have been run properly and stably from June 2003. Based on SE running, KPX had normalized real time Contingency Analysis, and study mode Power Flow, STNET and DTS. From early 2004, dispatchers have been trained to use NA and DTS for the purpose of stable SE running, NA operation & results reading and urgent equipment outage reviewing. EMS NA have been greatly contributed to operate real time power system stably. Above NA normal operation by KPX own efforts under the no experience of NA running, KPX made a good precedent. This paper is intended to introduce EMS NA normalization process, operation status, and etc in Korea power system operation.

• 전기학회논문지
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• 제59권3호
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• pp.492-498
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• 2010

Since it is almost impossible to train the dispatchers with real power system, the dispatcher training simulator(DTS) is used for the training. Among various components of the DTS, the power system model(PSM) emulates the dynamic behavior of the power system to calculate the frequency and voltage. The frequency is calculated from various parameters such as mechanical power of power plants, load, inertia, and the damping of the power system. In the PSM, the power plants are modeled as differential equations, so the mechanical power of the power plants are calculated by the numerical methods. Conventionally, the fixed step-size algorithm has been used in the PSM, however it has some drawbacks. This paper develops the prototype PSM using the Matlab, and analyzes the problems of the fixed step-size algorithm by comparing the results with those of PSCAD simulation. In order to overcome the limitations, this paper proposes a modified frequency calculation method using the adaptive step-size algorithm. From the simulation using the proposed method, it is verified that the accuracy of frequency calculation increases substantially while the simulation time is not greatly increased.

• 한국지반환경공학회 논문집
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• 제16권6호
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• pp.39-43
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• 2015

This study extends the Distributed Temperature Sensing (DTS) application to delineate the saturated zones in shallow sediment and evaluate the groundwater flow in both downward and upward directions. Dry, partially and fully saturated zones and water level in the subsurface can be recognized from this study. High resolution seepage velocity in vertical direction was estimated from the temperature data in the fully saturated zone. By a single profile, water level can be detected and seepage velocity in saturated zone can be estimated. Furthermore, thermal gradient analysis serves as a new technique to verify unsaturated and saturated zones in the subsurface. The vertical seepage velocity distribution in the recognized saturated zone is then analyzed with improvement of Bredehoeft and Papaopulos' model. This new approach provides promising potential in real-time monitoring of groundwater movement.

• Ocean Systems Engineering
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• 제7권1호
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• pp.21-38
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• 2017

In real sea environments, excessive dynamic axial tension variations can be exerted on the top-tensioned risers (TTRs) and lead to structural integrity issues. The traditional riser-tension-variation analysis, however, by using parametric formulation is only conditionally valid under certain strict limits and potentially underestimates the total magnitudes of tension variations. This phenomenon is especially important for the long stroke tensioner in dry-tree semisubmersible with larger global heave motion and longer stroke. In this paper, the hydro-pneumatic tensioner (HPT) is modeled in detailed component-level which includes a set of hydraulic and pneumatic components. The viscous fluid frictional effect in the HPT is considered. The main objectives are (i) to develop a detailed tension variation model of the HPT; (ii) to identify the deviations between the conventional parametric formulation and component-level formulation; (iii) to numerically analyze the tension variation of long stroke tensioner in a dry-tree semisubmersible (DTS). The results demonstrate the necessity of component-level formulation for long stroke tensioner in the development of DTS.