• The Journal of the Korea Contents Association
• /
• v.19 no.8
• /
• pp.151-158
• /
• 2019

The high-technological in the electric and electronic industries is recognized in overseas markets as well. However, the competition for technologies in these industries is increasing. Therefore, electric and electronic firms should be more efficient in their production. so, This paper analyzes the efficiency of High-growth Electrical and Electronics firms using DEA model. We evaluate the CCR, BBC efficiency and RTS(return to scale) of 20 Korean high-growth Electrical and Electronics firms. There are a total of 12 efficient DMUs with a BCC of 1. There are a total of 4 efficient DMUs with a CCR of 1. A total of 11 DMUs were IRS in Scale Efficiency and a total of 6 DMUs were CRS in Scale Efficiency and a total of 3 DMUs were DRS in Scale Efficiency. We also suggest the Electrical and Electronics firms which can be benchmarked based on analyzed information.

• Journal of Industrial Convergence
• /
• v.18 no.6
• /
• pp.27-32
• /
• 2020

Recently, as the business using IT has increased rapidly, a lot of budget is required to operate and manage the complex IT infrastructure. There is a need for a new IT infrastructure technology that can effectively and reduce costs. In this paper, we introduce CI(Converge Infrastructure) and HCI(Hyper Converge Infrastructure) methods, which are IT infrastructure methods for simplifying information systems and reducing operational management efficiency and cost. In addition, it proposes an information system using the HCI method, a new IT infrastructure technology, and a plan to establish a disaster recovery system to provide continuity of service in the event of a disaster or failure. In addition to the introduction of major technologies for using the HCI method, the area, power consumption, and operational efficiency of the information system before and after the introduction of HCI are compared and analyzed.

• Journal of Korean Neurosurgical Society
• /
• v.64 no.4
• /
• pp.608-618
• /
• 2021

Objective : The endoscopic endonasal transsphenoidal approach is a widely-used method for the surgical treatment of pituitary adenomas. We aimed to evaluate the results of endoscopic surgery by comparing preoperative classification methods and investigating their relationship with postoperative resection and remission rates and complications. Methods : We retrospectively reviewed the medical records of 236 patients (118 males) who underwent surgery for pituitary adenomas. Preoperative Knosp classification, tumor size (TS), suprasellar extension (SSE), postoperative resection and remission rates, and complications were evaluated. Results : The follow-up period was 3 months to 6 years. The patients' ages ranged between 16 and 84 years. Endocrinologically, 114 patients (48.3%) had functional adenoma (FA), and 122 patients (51.7%) had non-functional adenoma (NFA). Among the FA group, 92 (80.7%) showed remission. A statistically significant difference was found between patients with and without remission in terms of the Knosp, TS, and SSE classifications (p<0.01). Knosp, TS, and SSE classification grades were found to be correlated with the resection rates (p<0.01). Meningitis was seen in seven patients (3.0%), diabetes insipidus in 16 (6.9%; permanently in two [0.9%]), and rhinorrhea in 19 (8.1%). Thirty-six patients (15.3%) developed pituitary insufficiency and received hormone replacement therapy. Conclusion : The resection categories and remission rates of FAs were directly proportional to the adenoma sizes and Knosp grades, while the degree of suprasellar growth further complicated resection and remission rates. Adenoma sizes less than 2 cm and SSEs less than 1 cm are associated with favorable remission and resection rates.

• Development and Reproduction
• /
• v.25 no.4
• /
• pp.225-234
• /
• 2021

The present study aimed to investigate the mechanism of cell surface receptor loss by two constitutively activating mutants (designated L469R, and D590Y) and two inactivating mutants (D417N and Y558F) of the luteinizing hormone receptor (LHR) in the Japanese eel Anguilla japonica, known to naturally occur in human LHR transmembrane domains. We investigated cell surface receptor loss using an enzyme-linked immunosorbent assay in HEK 293 cells. The expression level of wild-type eel LHR was considered to be 100%, and the expression levels of L469R and D417N were 97% and 101%, respectively, whereas the expression levels of D590Y and Y558F slightly increased to approximately 110% and 106%, respectively. The constitutively activating mutants L469R and D590Y exhibited a decrease in cell surface loss in a manner similar to that of wild-type eel LHR. The rates of loss of cell surface agonist-receptor complexes were observed to be very rapid (2.6-6.2 min) in both the wild-type eel LHR and activating mutants. However, cell surface receptor loss in the cells expressing inactivating mutants D417N and Y558F was slightly observed in the cells expressing inactivating mutants D417N and Y558F, despite treatment with a high concentration of agonist. These results provide important information on LHR function in fish and the regulation of mutations of highly conserved amino acids in glycoprotein hormone receptors.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.22 no.5
• /
• pp.377-385
• /
• 2022

Background: Postoperative endodontic pain is an enigma for the dentist. This study aimed to evaluate the analgesic effect of 300 mg gabapentin or 75 mg pregabalin in reducing postoperative endodontic pain compared with a placebo. Methods: Ninety patients who needed root canal treatment with an initial numerical rating scale (NRS) pain score of > 4 (T0) were randomly divided into three groups (n=30). Patients were then administered either 300 mg gabapentin (group A), 75 mg pregabalin (group B), or a placebo (group C) 30 min prior to the start of endodontic treatment. A single operator performed single-visit endodontics, and pain was evaluated immediately after endodontic treatment (T1) and at 4 h (T2), 8 h (T3), 12 h (T4), 24 h (T5), 48 h (T6), and 72 h (T7) using the NRS. Ibuprofen/paracetamol (400 mg/325 mg) was administered as a rescue dose if needed. Results: Pregabalin performed significantly better when compared with gabapentin at all time points except at 72 h after treatment (P=0.170). The placebo group showed significantly higher pain scores than the other two groups. The percentage of pain relief was maximum for pregabalin (92.1%), followed by gabapentin (87.6%) and placebo (69.1%) at 72 h after treatment completion. Conclusion: This study showed that pretreatment with a single dose of pregabalin and gabapentin both had greater analgesic effects than a placebo. They can be effectively used to reduce postoperative endodontic pain.

• Development and Reproduction
• /
• v.27 no.2
• /
• pp.91-99
• /
• 2023

The sea cucumber, Apostichopus japonicus, is one of the most valuable aquatic species. The color of body wall and appearance are important for the value of sea cucumbers. To examine expression pattern of long-chain acyl-coenzyme A dehydrogenase (LCAD), nuclear distribution C-containing protein 3 (NUDCD3), and receptor tyrosine kinase Tie-1 (TIE1), previously reported as differently expressed genes during the pigmentation of sea cucumber, we analyzed the temporal profiles of LCAD, NUDCD3, and TIE1 mRNAs in LED-exposed and light-shielded A. japonicus. Real-time quantitative PCR revealed that the LCAD, NUDCD3, and TIE1 mRNAs from the juveniles at 40-60 days post-fertilization (dpf) exhibited increasing patterns as compared to those of an early developmental larva (6-dpf). At 60-dpf juveniles, the LCAD and TIE1 mRNA levels of LED-exposed individuals were higher than those of light-shielded ones, whereas at 40-dpf and 50-dpf juveniles, the NUDCD3 mRNA expression was higher in the light-shielded condition (p<0.05). In the pigmented juveniles (90-dpf), the LCAD and TIE1 mRNA levels tended to show higher levels in red individuals than those in green ones, but there was a conversely higher level of NUDCD3 mRNA in green larva. In situ examination of LCAD and NUDCD3 mRNAs in light-shielded 6-dpf larva revealed that both genes are mainly expressed in the internal organs compared to the body surface. Together, these results may provide insights into the differential gene expression of LCAD, NUDCD3, and TIE1 during pigmentation process of the sea cucumber.

• Journal of the Korean Society of Food Culture
• /
• v.23 no.3
• /
• pp.336-347
• /
• 2008

The purpose of this study is to analyze the articles of food and nutrition published in the Yeo-Sung magazines from 1936 to 1940 in Korea. Out of the 67 articles about the food and the nutrition from the Yeo-Sung magazines, 28 (41.8%) of them were about the brief information of food and nutrition news, 16 (23.8%) of them were about the recipes, 6 (9.0%) were about the nutrition information, and 17 (25.4%) of them were about others. As the number of recipes mentioned from the Yeo-Sung magazine was 103, 77 items, the majority, were about the Korean foods, 18 of the Western foods, 6 of Chinese foods, and only 2 of Japanese foods. This result showed that the Japanese colonization didn't seem to influence on Korean tastes and gastronomy. During this period, the modernization caused the numerous changes to our traditional cuisine with introduction of new western menu items and concept of nutrition. The nutrition articles highly recommended eating brown rice, vegetables, tofu, and the white meat. Shin-Young Bang, one of the main authors, insisted that "Cookery is not only the skill, but also the one of the very important academic sciences." showed budding modern cookery sciences in Korea.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.26 no.6
• /
• pp.291-300
• /
• 2023

Purpose: The impact of coronavirus 2019 (COVID-19) on gastrointestinal (GI) endoscopy procedures in adults has been reported, with a drastic reduction in the number of procedures. However, there are no sufficient data regarding the impact on pediatric GI endoscopy. Here, we aimed to report that impact in the Asia-Pacific region. Methods: A questionnaire-based internet survey was conducted from June to November 2021 among pediatric endoscopy institutions in the Asia-Pacific region, with each institution providing a single response. Overall, 25 questions focused on the impact of the number of procedures conducted, the usage of personal protective equipment (PPE), and endoscopy training programs during the pandemic. Results: A total of 162 institutions across 13 countries in the Asia-Pacific region participated in the study, and 133 (82.1%) institutions underwent procedure changes since the emergence of COVID-19. The number of esophagogastroduodenoscopy and ileocolonoscopy procedures decreased in 118/133 (88.7%) and 112/133 (84.2%) institutions, respectively. Endoscopy for patient with positive COVID-19 in an emergency or urgent cases still carried out in 102/162 (62.9%) institutions. Screening of COVID-19 for all patients before endoscopy was done across 110/162 (67.9%) institutions. PPE recommendations varied among institutions. Pediatric gastrointestinal endoscopy training programs were discontinued in 127/162 (78.4%) institutions. Conclusion: This study reports the impact of the COVID-19 pandemic on pediatric gastrointestinal endoscopy in the Asia-Pacific region. There has been a significant reduction in the number of endoscopic procedures and relevant training programs.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.27 no.2
• /
• pp.95-103
• /
• 2024

Purpose: Diarrhea is one of the leading causes of mortality in children living in developing countries. The etiology of acute diarrhea in each healthcare center varies depending on place, time, and population. This study aimed to identify pathogen patterns in human immunodeficiency virus (HIV)-infected and non-HIV children suffering from acute diarrhea, using multiplex real time reverse transcriptase polymerase chain reaction (RT-PCR), in an Indonesian tertiary hospital. Methods: This cross-sectional study was conducted at Dr. Cipto Mangunkusumo National Hospital from March 2019 to April 2020. Results: The study showed that multiplex RT-PCR results were positive in 58.9% of the specimens, with more positive results in HIV-infected children than in non-HIV-infected children (70% vs. 54.7%). Altogether 72 enteropathogens were detected from all specimens. Enteropathogens in non-HIV children with acute diarrhea consisted of bacteria (70.6%) and viruses (29.4%) with a predominance of enteroaggregative Escherichia coli (25.4%), followed by Campylobacter spp. (11.8%), enteropathogenic E. coli (9.8%), Norovirus GII (7.8%), and Clostridium difficile (7.8%). Enteropathogens in HIV-infected children consisted of viruses (57.1%), bacteria (28.6%), and parasites (14.3%) comprising Norovirus GII (24%), Cryptosporidium spp. (14.3%), Campylobacter spp. (14.3%), Norovirus GI (14.3%), and Astrovirus (14.3%). Cryptosporidium spp. was the only parasite found in this study and was found only in HIV-infected children. In non-HIV children with acute diarrhea, most pathogens were invasive bacteria, while in HIV-infected children, more viral and parasite infections occurred, primarily caused by opportunistic pathogens. Conclusion: The pattern of enteropathogens can help clinicians determine further examinations and appropriate empirical antimicrobial therapy for the patient.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.11 no.1
• /
• pp.25-39
• /
• 1984

The author has sought to determine the time and the sequence of permanent teeth eruption in Korean children. The study group consisted of 15,671 healthy children (male 8,015 ; female 7,656) aged 5-13 years old who lived in Seoul or Cheongju. The results were as follows : 1. The eruption times of permanent teeth were 0.45 years earlier in females than in males. 2. The ages corresponding to $ER_{50}$ of permanent teeth were as follows : In Maxilla 1) central incisor was 7.37 yrs 2) lateral incisor was 8.50 yrs 3) canine was 10.83 yrs 4) 1st premolar was 10.30 yrs 5) 2nd premolar was 11.09 yrs 6) 1st molar was 6.49 yrs 7) 2nd molar was 12.79 yrs In Mandible 1) central incisor was 6.40 yrs 2) lateral incisor was 7.41 yrs 3) canine was 10.18 yrs 4) 1st premolar was 10.26 yrs 5) 2nd premolar was 11.15 yrs 6) 1st molar was 6.32 yrs 7) 2nd molar was 12.05 yrs 3. The eruption sequence of permanent teeth by Z-test was as follow: In Male 1st : Mandibular 1st molar, and Mandibular central incisor 2nd : Maxillary 1st molar 3rd : Maxillary central incisor 4th : Mandibular lateral incisor 5th : Maxillary lateral incisor 6th : Mandibular canine, Maxillary and Mandibular 1st premolar 7th : Maxillary canine 8th : Maxillary and Mandibular 2nd premolar 9th : Mandibular 2nd molar 10th : Maxillary 2nd molar In Female 1st : Mandibular 1st molar, and Mandibular central incisor 2nd : Maxillary 1st molar 3rd : Mandibular lateral incisor, Maxillary central incisor 4th : Maxillary lateral incisor 5th : Mandibular canine, Maxillary and Mandibular 1st premolar 6th : Maxillary canine 7th : Maxillary and Mandibular 2nd premolar 8th : Mandibular 2nd molar 9th : Maxillary 2nd molar 4. The corresponding permanent teeth in the mandible generally erupted earlier than the corresponding permanent teeth in the maxilla by an average of 0.73 years, but the mean eruption time of mandibular 1st premolars was almost the same as those of maxillary 1st premolars, and the mean eruption time of mandibular 2nd premolars was 0.06 years later than those of maxillary 2nd premolars. 5. There is no significant difference between left and right arch in the eruption time and sequence. 6. Generally, the ages of permanent teeth eruption tended to be earlier than those of Dr. Cha's data from 1963.