• Title/Summary/Keyword: DR6

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Effects of the Insulin-like Growth Factor Pathway on the Regulation of Mammary Gland Development

  • Ha, Woo Tae;Jeong, Ha Yeon;Lee, Seung Yoon;Song, Hyuk
    • Development and Reproduction
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    • v.20 no.3
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    • pp.179-185
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    • 2016
  • The insulin-like growth factor (IGF) pathway is a key signal transduction pathway involved in cell proliferation, migration, and apoptosis. In dairy cows, IGF family proteins and binding receptors, including their intracellular binding partners, regulate mammary gland development. IGFs and IGF receptor interactions in mammary glands influence the early stages of mammogenesis, i.e., mammary ductal genesis until puberty. The IGF pathway includes three major components, IGFs (such as IGF-I, IGF-II, and insulin), their specific receptors, and their high-affinity binding partners (IGF binding proteins [IGFBPs]; i.e., IGFBP1-6), including specific proteases for each IGFBP. Additionally, IGFs and IGFBP interactions are critical for the bioactivities of various intracellular mechanisms, including cell proliferation, migration, and apoptosis. Notably, the interactions between IGFs and IGFBPs in the IGF pathway have been difficult to characterize during specific stages of bovine mammary gland development. In this review, we aim to describe the role of the interaction between IGFs and IGFBPs in overall mammary gland development in dairy cows.

Influence of brass laminate volume fraction on electromechanical properties of externally laminated coated conductor tapes

  • Bautista, Zhierwinjay M.;Shin, Hyung-Seop;Lee, Jae-Hun;Lee, Hunju;Moon, Seung-Hyun
    • Progress in Superconductivity and Cryogenics
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    • v.18 no.3
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    • pp.6-9
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    • 2016
  • The enhancement of mechanical properties of coated conductor (CC) tapes in practical application are usually achieved by reinforcing through lamination or electroplating metal layers on either sides of the CC tape. Mechanical or electromechanical properties of the CC tapes have been largely affected by the lamination structure under various loading modes such as tension, bending or even cyclic. In this study, the influence of brass laminate volume fraction on electromechanical properties of RCE-DR processed Gadolinium-barium-copper-oxide (GdBCO) CC tapes was investigated. The samples used were composed of single-side and both-side laminate of brass layer to the Cu-stabilized CC tape and their $I_c$ behaviors were compared to those of the Cu-stabilized CC tape without external lamination. The stress/strain dependences of $I_c$ in laminated CC tapes under uniaxial tension were analyzed and the irreversible stress/strain limits were determined. As a result, the increase of brass laminate volume fraction initially increased the irreversible strain limit and became gradual. The corresponding irreversible stress limit, however, showed no difference even though the brass laminate volume fraction increased to 3.4. But the irreversible load limit linearly increased with the brass laminate volume fraction.

The Nursing Record Evaluation of the Application of the Nursing Process (간호과정 적용에 따른 간호기록지 평가)

  • 이경혜;김문실
    • Journal of Korean Academy of Nursing
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    • v.10 no.2
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    • pp.87-94
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    • 1980
  • According to the provious study. it was suggested a need for improvement of nursing care through application of nursing process in Ewha Womans University Hospital With those data. it has been applied to the nursing care at maternity ward by nurses. This study was undertaken to determine the evaluation of the application of the nursing process which is an orderly. systemic min of deforming the patient's/client's nursing problems. This study involved 191 cases with patient chart and was carried out from Feb. 1979 to Feb. 1980 is Ewha Womans University Hospital. The results were as follows : 1. Actual performance of“Assessment”stage was 59%, and 45 % for the nursing diagnosis. 2. It was achieved with specific planning of nursing care for 71.6% and the plan was safely and effective implemented (97.9% ). 3. Afer“Implement”stage it was made of evaluation and feedback process (39%). 4. Nurses in Eha womans University hospital. they showed the Positive attitude toward the application of nursing process. but they saggested that there were lack of manpower and the consideration of time allocation. Recommandation are as follows : 1. All nursing staff must participate in continious education program for nursing process. 2. The results suggest a need for modification for the nursing history formeat and SOAPIER. 3. A need for improvement of physical condition for interview and effective utilization of nursing staff. 4. It will more effective when Dr's medical record replace by problem ariented aedical record( POMR).

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A New 12-Pulse Diode Rectifier System With Low kVA Components For Clean Power Utility Interface

  • ;Prasad N.Enjeti
    • The Transactions of the Korean Institute of Power Electronics
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    • v.4 no.5
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    • pp.423-432
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    • 1999
  • This paper proposes a 12­pulse diode rectifier system with low kVA components suitable for powering switch mode power supplies or ac/dc converter applications. The proposed 12-pulse system employs a polyphase transformer, a zero sequence blocking transformer (ZSBT) in the dc link, and an interphase transformer. Results produce near equal leakage inductance in series with each diode rectifier bridge ensuring equal current sharing and performance improvements, The utility input currents and the voltage across the ZSBT are analyzed the kVA rating of each component in the proposed system is computed. The 5th , 7th , 17th and 19th harmonics are eliminated in the input line currents resulting in clean input power. The dc link voltage magnitude generated by the proposed rectifier system is nearly identical to a conventional to a conventional 6-pulse system. The proposed system is suitable to retrofit applications as well as in new PWM drive systems. Simulation and experimental results from a 208V , 10kVA system are shown.

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Efficacy of Seo Dong-Il's Technique as a Method of Improving Voice Quality in Patients with Phonasthenia and Vocal Nodules

  • Seo, Dong-Il;Yoo, Jae-Yeon;Choi, Hong-Shik;Jeong, Ok-Ran
    • Speech Sciences
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    • v.9 no.3
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    • pp.77-86
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    • 2002
  • The purpose of this study was to investigate the effects of Sea Dong-Il's technique on voice quality in patients with vocal nodules and phonasthenia (vocal fatigue). Ten patients (4 nodules and 6 vocal fatigue) participated in the study. Each subject was assessed acoustically (Fo, Jitter, Shimmer, NNE) in the first and last session. Dr. Speech (version 3.4, Tiger-DRS) was used to compare acoustic parameters of pre-and post-treatment. Sea Dong-Il's technique consisted of breathing exercise, relaxation exercise, and phonation exercise. The results were as follows: First, Sea Dong- Il's technique tended to be effective on improving voice quality in patients with phonasthenia and vocal nodules. Second, the nature of improvements were as follows: there was a significant difference between pre-and post-treatment in shimmer (p < .01) and NNE (p < .001), while there was no significant difference between pre-and post-treatment in Fo and Jitter. Finally, given the fact that the number of subjects was only 10, the jitter might have shown a significant difference if more subjects participated in the experiment.

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SIMULTANEOUS SURGICAL REPOSITIONING OF THE MAXILLA, MANDIBLE, AND CHIN (상악골, 하악골 및 이부의 외과적 동시 이동술)

  • Lee, Jae-Hwy;Lee, Ho-Jun;Hwang, Byung-Nam;Lee, Jeong-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.2
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    • pp.184-199
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    • 1996
  • The challenges to achieve three dimensional facial proportionality and occusal stability in many patients with complex dentofacial deformity have been met by the development and use of the maxilla, mandible, and chin surgery techniques in combination with efficient orthodontic treatment. There is a clinical, biological, and biomechanical foundation for simultaneous surgical repositioning of the maxilla, mandible, and chin in a significant proportion of adult and adolescent patients. A combination of the surgical and orthodontic approach may provide increased treatment efficiencies and optimal esthetic results. Art and science to determine the treatment objectives, specifically, the desired soft tissue changes are firstly established by using the clinician's "esthetic sense" of the facial beauty and proportion aided to a few cephalometric guidelines. In this sense, the dependence on the clinician's "esthetic eye" by Dr. Bell is more important in analyzing the facial proportion than the satisfaction of rigid cephalometric norms. The purpose of this article was to elucidate the indication for simultaneous surgical repositioning of the maxilla, mandible, and chin, and to describe the clinical cephalometric analysis for orthognathic surgery. Representative 6 case reports were presented and discussed to illustrate the esthetic, orthodontic, and surgical treatment objectives with long-term follow-up.

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Carbonic Anhydrase Mimicry for Carbon Dioxide Fixation and Calcium Carbonate Mineralization (탄산탈수효소 모사를 이용한 이산화탄소 고정화 및 탄산칼슘 합성)

  • Sahoo, Prakash C.;Jang, Young Nam;Chae, Soo Chun;Lee, Seung Woo
    • Particle and aerosol research
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    • v.9 no.4
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    • pp.201-208
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    • 2013
  • Copper (II) and Nickel (II) mimic complexes of enzyme carbonic anhydrase were evaluated under ambient condition for carbon dioxide capture and conversion process. The synthesized complexes were characterized by ATR-FTIR and UV-DR spectroscopy. It was found that all the complexes have biomimetic activity towards $CO_2$ using para-nitrophenyl acetate (p-NPA) hydrolysis as the model reaction. Interestingly, the proper geometry obtained by the restricted orientation of tripodal N atoms in Cu (II) complex of 2,6-bis(2-benzimidazolyl) pyridine showed the highest activity (1.14 au) compared to others. The $CO_2$ bio-mineralization to $CaCO_3$ was carried out via in-vitro crystallization approach. Results indicate that the biomimetic complexes have a role in determining $CaCO_3$ morphology. The present observations establish a qualitative insight for the design of improved small-molecule catalysts for carbon capture.

An InGaP/GaAs HBT Monolithic VCDRO with Wide Tuning Range and Low Phase Noise

  • Lee Jae-Young;Shrestha Bhanu;Lee Jeiyoung;Kennedy Gary P.;Kim Nam-Young
    • Journal of electromagnetic engineering and science
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    • v.5 no.1
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    • pp.8-13
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    • 2005
  • The InGaP/GaAs hetero-junction bipolar transistor(HBT) monolithic voltage-controlled dielectric resonator oscillator(VCDRO) is first demonstrated for a Ku-band low noise block down-converter(LNB) system. The on-chip voltage control oscillator core employing base-collector(B-C) junction diodes is proposed for simpler frequency tuning and easy fabrication instead of the general off-chip varactor diodes. The fabricated VCDRO achieves a high output power of 6.45 to 5.31 dBm and a wide frequency tuning range of ]65 MHz( 1.53 $\%$) with a low phase noise of below -95dBc/Hz at 100 kHz offset and -115 dBc/Hz at ] MHz offset. A]so, the InGaP/GaAs HBT monolithic DRO with the same topology as the proposed VCDRO is fabricated to verify that the intrinsic low l/f noise of the HBT and the high Q of the DR contribute to the low phase noise performance. The fabricated DRO exhibits an output power of 1.33 dBm, and an extremely low phase noise of -109 dBc/Hz at 100 kHz and -131 dBc/Hz at ] MHz offset from the 10.75 GHz oscillation frequency.

Ell3 Modulates the Wound Healing Activity of Conditioned Medium of Adipose-derived Stem Cells

  • Lee, Jae-Yong;Oh, Nuri;Park, Kyung-Soon
    • Development and Reproduction
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    • v.21 no.3
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    • pp.335-342
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    • 2017
  • While adipose-derived stem cell-conditioned medium (ADSC-CM) has been demonstrated to promote skin wound healing, the mechanism regulating this effect remains unelucidated. In this study, we aimed to investigate the role of Ell3 in the wound healing activity of ADSC-CM. In vitro analysis revealed that Ell3 suppression in ADSCs impairs the promotive activity of ADSC-CM on the proliferation and migration of mouse embryonic fibroblasts (MEF) and normal human dermal fibroblasts (NHDF). Consistently, the expression of MMP family genes, which regulate cell proliferation and migration, was significantly suppressed in MEF and NHDF treated with siEll3-transfected ADSC-CM. Proinflammatory cytokines, such as interleukin-1 and interleukin-6, were highly expressed in MEF treated with siEll3-transfected ADSC-CM. The wound healing activity of siEll3-transfected ADSC-CM was significantly lower than that of the control in vivo. Our results suggest that Ell3 may contribute to the inhibition of inflammatory response during skin wound healing.

A Study on the Expression f Clothing and Textiles Recoreded in "Eigamonokatary" ($\ulcorner영화물언\urcorner$에 나타난 복식자료 연구)

  • 문광희
    • Journal of the Korean Society of Costume
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    • v.35
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    • pp.293-304
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    • 1997
  • This paper is a study on the expression of Clothing and Textiles recorded in $\boxDr$Eigamono-katary$\boxUl$This book is a novel de-scribed the Royal Court from 883 till 1107. In this book many kinds of Garments Orna-ments Colors and Materials were mentioned. But in this paper 69 kinds of Garments and Ornaments were reserched and the rest will be reported in the next paper, The discoveries of this paper were as follows. 1. All the things of this book were reflections of the reality in Heian period. 2. The main styling of that period was a little bit soft but the straight silhouette were fashioned, . In that time Clothing had a special meaning and the manner for a fashion was very important, .3 In the female garments Karakoromo were developed many kinds of pattern by dyeing method, Especially the Surizome was fashioned very much. 4. there were many kinds of gray tone like as clerical robe and mouning dress. This was the effection of Buddism style. 5. The decoration of fablics and garments were usualized for instance smooding and luster by beating and starch sewuing a piece of gold silver and shell nakabe and knot bend. Shawl Yumaki and Kosizasi was a charming point of that time, . 6, hair decoration shose parasol rain coat etc, . were developed and use freuently.

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