• Biomolecules & Therapeutics
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• 제8권2호
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• pp.147-152
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• 2000

The rodent uterotrophic assay is currently recommended as one of the primary in vivo assays far endocrine disrupting chemicals by the Organization for Economic Cooperation and Development (OECD) and Endocrine Disruptor Screening and Testing Advisory Committee (US EPA EDSTAC). Generally, this assay relies on the rapid increase in uterus and vagina weights when exposed to estrogenic compounds. Phthalate esters have been used extensively as a plasticizer in the manufacture of plastic products such as PVC films and medical devices. Recently, phthalate esters have been shown to induce endocrine system mediated responses. However, a flew studies have been conducted for the screening of their estrogenic activity. In this study the estrogenic activity of seven phthalate esters, butyl benzyl phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), di-n-butylphthalate (DBP), diethylphthalate (DEP), di-n-pentylphthalate (DPF), di-n-propylphthalate (DPrP) and dicyclohexylphthalate (DCHP), was examined in uterotrophic assay. Phthalate esters dissolved in corn oil were administered to ovariectomized (OVX) female Sprague-Dawley rats by sub-cutaneous injection for three consecutive days. fiats were sacrificed 24h after final treatment, and then uterus and vagina weights were deter mined. All phthalate esters tested in this assay did not change talc uterus and vagina weights at dosage levels up to 200 mg/kg/day treatment. These results demonstrated that phthalate esters did not exhibit estrogenic activity in vivo uterotrophic assay.

• 한국생산제조학회지
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• 제18권4호
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• pp.337-347
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• 2009

Generally, finite element models used in structural analysis have some uncertainties of the geometric dimensions, applied loads and boundary conditions, as well as in material properties due to the manufacturability of aluminum intensive body. Therefore, it is very important to refine or update a finite element model by correlating it with dynamic and static tests. The structural optimization problems of automotive body are considered for mechanical structures with initial stiffness due to preloading and in operation condition or manufacturing. As the mean compliance and deflection under preloading are chosen as the objective function and constraints, their sensitivities must be derived. The optimization problem is iteratively solved by a sequential convex approximation method in the commercial software. The design variables are corrected by the strain energy scale factor in the element levels. This paper presents an updated method based on the sensitivities of structural responses and the residual error vectors between experimental and simulation models.

• The Journal of Asian Finance, Economics and Business
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• 제7권10호
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• pp.531-541
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• 2020

This study aims to determine the nature of the association between dividend policy and a corporation's financial performance in emerging countries, as well as the main variables that may have an effect on financial performance. The study included 92 industrial and service sector companies listed on the Amman Stock Exchange (ASE) during the period from 2015 to 2019. The study used Panel Data Analysis and cross-sectional time-series data and simple and multiple linear regression models. A multiple regression model was also developed in order to test whether guess factors may have a possible impact on financial performance (such as Dividend Yield, Dividend Pay-out Ratio, Firm Size, Leverage Ratio, Current Ratio). The data was collected from the annual reports and information that was available on the ASE website covering the period from 2015 to 2019. The results detect a strong relation between DY, DPR, and FSIZE variables that explain firm performance. Also leverage ratio is negatively and significantly associated with ROA and AOE. Moreover, no relations were detected between current ratio and financial performance. The study's conclusion is that dividend policy explains a lot of a company's financial performance, meaning that the dividend policy has a statistically significant impact on company financial performance.

• 혜화의학회지
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• 제19권1호
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• pp.75-86
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• 2010

These days, traditional and complementary/alternative medicine (TM/CAM) becomes more upsurging topics of increasing importance and the use and popularity of TM/CAM is rapidly expanding, Since the tradition and situation on TM/CAM of each country is quite different, the concept and system of TM/CAM expressed by different countries shows the variety of range. Some countries recognize TM/CAM as one part of two branches of medical science and have integrated into national health care system. In these countries, education systems for TM/CAM are also well organized formal education systems, such as the Republic of Korea, DPR Korea, China (including Hong Kong and Macao), and Viet Nam. However, other countries in Asia and the Pacific. still do not have formal and/or informal education system and do not recognize TM/CAM as a kind of health care systems. This paper reviews the current situation of education and training on TM/CAM in the Asia and the Pacific. As a result, fifteen countries (31.3%) of 48 member countries in Asia and the Pacific have formal education systems for TM/CAM, twelve countries (25.0%) do not have formal education system and twenty one countries (43.7%) do not have available information. At least six countries are allocating the curriculum of medical school to the education of both allopathic and traditional medicine. For the proper use and development of TM/CAM, the development of formal education system as well as the integration into the national health care system are needed.

• 헤리티지:역사와 과학
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• 제36권
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• pp.39-67
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• 2003

In this paper we examine cultural properties of the North Korea from 'the law of the Democratic People's Republic of Korea on Protection of Cultural Property". This law was adopted the Resolution of the Standing Committee of the Supreme People's Assembly of DPR of Korea in 1994. For our study, some other laws or rules established after the end of Japanese colonial occupation (1910-1945) in North Korea were examined. The policy on protection and conservation of cultural property in North Korea seems to have taken place a relatively rapid. The purpose of this law is to carry out the policy with a view to contributing to establishment of strict system and order for protection and management of cultural property, to their preservation in original state, to their proper inheritance and development, and to enhancement of national pride and confidence among the people. This law consists of 6 chapters (52 articles): (1) Fundamentals of the law on protection of cultural property, (2) Archaeological excavation and collection of cultural relics, (3) Evaluation and registration of cultural property, (4) Preservation and management of cultural property, (5) Restoration of cultural property, and (6) Guidance and control of cultural property protection. Nevertheless, it is difficult to find the evidence of efforts to exploit the cultural properties from an academic point of view in North Korea since the late 1980s.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.885-894
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• 2021

This study aims to analyze the effect of the ratio of profitability and solvability (leverage) on the variable stock price, which is mediated (intervening) by the variable dividend policy. Using the financial reports of manufacturing companies in the consumer goods sector, we take profitability data (ROA, ROE, GPM, and NPM), solvability data (DAR, LTDER, and DER), dividend policy (DPR), and stock price (closing price) from 24 companies, which were selected as samples, from 2011 to 2018. Data was analyzed using the Structural Equation Modeling (SEM) method. The results show that profitability, solvability, and dividend policy affect changes in stock prices, respectively. On the other hand, profitability and solvability do not affect dividend policy. The indirect relationship (intervening) is assessed using a single test, resulting in a dividend policy that can intervene in the relationship between profitability and stock prices but cannot mediate the relationship between solvability and stock prices. The implication of this research is to provide knowledge to investors about the importance of knowing the company's financial performance. Companies with good financial performance will easily develop because there are sufficient funds for company operations. By analyzing financial ratios, investors can get signals to decide whether to invest in the company they want.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 2022년도 제34회 한글 및 한국어 정보처리 학술대회
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• pp.131-134
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• 2022

자연어처리 분야 중 질의응답 태스크는 전통적으로 많은 연구가 이뤄지고 있는 분야이며, 최근 밀집 벡터를 사용한 리트리버(Dense Retriever)가 성공함에 따라 위키피디아와 같은 방대한 정보를 활용하여 답변하는 오픈 도메인 QA(Open-domain Question Answering) 연구가 활발하게 진행되고 있다. 대표적인 검색 모델인 DPR(Dense Passage Retriever)은 바이 인코더(Bi-encoder) 구조의 리트리버로서, BERT 모델 기반의 질의 인코더(Query Encoder) 및 문단 인코더(Passage Encoder)를 통해 임베딩한 벡터 간의 유사도를 비교하여 문서를 검색한다. 하지만, BERT와 같이 엔티티(Entity) 정보에 대해 추가적인 학습을 하지 않은 언어모델을 기반으로 한 리트리버는 엔티티 정보가 중요한 질문에 대한 답변 성능이 저조하다. 본 논문에서는 엔티티 중심의 질문에 대한 답변 성능 향상을 위해, 엔티티를 잘 이해할 수 있는 LUKE 모델 기반의 리트리버를 제안한다. KorQuAD 1.0 데이터셋을 활용하여 한국어 리트리버의 학습 데이터셋을 구축하고, 모델별 리트리버의 검색 성능을 비교하여 제안하는 방법의 성능 향상을 입증한다.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 2023년도 제35회 한글 및 한국어 정보처리 학술대회
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• pp.683-689
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• 2023

자연어 처리 분야는 최근에 큰 발전을 보였으며, 특히 초대규모 언어 모델의 등장은 이 분야에 큰 영향을 미쳤다. GPT와 같은 모델은 다양한 NLP 작업에서 높은 성능을 보이고 있으며, 특히 챗봇 분야에서 중요하게 다루어지고 있다. 하지만, 이러한 모델에도 여러 한계와 문제점이 있으며, 그 중 하나는 모델이 기대하지 않은 결과를 생성하는 것이다. 이를 해결하기 위한 다양한 방법 중, Retrieval-Augmented Generation(RAG) 방법이 주목받았다. 이 논문에서는 지식베이스와의 통합을 통한 도메인 특화형 질의응답 시스템의 효율성 개선 방안과 벡터 데이터 베이스의 수정을 통한 챗봇 답변 수정 및 업데이트 방안을 제안한다. 본 논문의 주요 기여는 다음과 같다: 1) QA Pair Passage RAG을 활용한 새로운 RAG 시스템 제안 및 성능 향상 분석 2) 기존의 LLM 및 RAG 시스템의 성능 측정 및 한계점 제시 3) RDBMS 기반의 벡터 검색 및 업데이트를 활용한 챗봇 제어 방법론 제안

• 환경위생공학
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• 제20권2호
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• pp.39-46
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• 2005

This study was Performed to survey and evaluate the contents of Plasticizers such as DEP(diethyl phthalate), DPrP(di-n-Phthalate), DBP(di-n-butyl Phthalate), DPP(di-n-pentyl Phthalate), DCHP(dicyclohexyl phthalate), BBP (butylbenzyl phthalate), DEHP(di-(2-ethylhexyl) phthalate) and DEHA(di-(2-ethylheryl) adipate), which are suspected as endocrine disruptors, in food and drug PVC packaging. Tested samples were 5 food wraps, 35 food containers, 40 food and drug packages(type of tablet and capsule) in Gyeonggi-Do area. The contents of DEHA in wrap were 188.9g/kg, 203.1g/kg, 238.4g/kg, 290.9g/kg and 308.3g/kg, respectively, while the other plasticizers were not detected. DEHP was used in 4 samples of food containers and DEHP contents were 4.7g/kg, 30.7g/kg, 35.8g/kg and 53.4g/kg, respectively. In food and drug packaging materials(type of tablet and capsule), the plasticizers were not detected.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume I
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• pp.7-10
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• 2006

Four programs, i.e. TRMM, ADEOS2, ASTER, and ALOS are going on in Japanese Earth Observation programs. TRMM and ASTER are operating well, and TRMM operation will be continued to 2009. ADEOS2 was failed, but AMSR-E on Aqua is operating. ALOS (Advanced Land Observing Satellite) was successfully launched on $24^{th}$ Jan. 2006. ALOS carries three instruments, i.e., PRISM (Panchromatic Remote Sensing Instrument for Stereo Mapping), AVNIR-2 (Advanced Visible and Near Infrared Radiometer), and PALSAR (Phased Array L band Synthetic Aperture Radar). PRISM is a 3 line panchromatic push broom scanner with 2.5m IFOV. AVNIR-2 is a 4 channel multi spectral scanner with 10m IFOV. PALSAR is a full polarimetric active phased array SAR. PALSAR has many observation modes including full polarimetric mode and scan SAR mode. After the unfortunate accident of ADEOS2, JAXA still have plans of Earth observation programs. Next generation satellites will be launched in 2008-2012 timeframe. They are GOSAT (Greenhouse Gas Observation Satellite), GCOM-W and GCOM-C (ADEOS-2 follow on), and GPM (Global Precipitation Mission) core satellite. GOSAT will carry 2 instruments, i.e. a green house gas sensor and a cloud/aerosol imager. The main sensor is a Fourier transform spectrometer (FTS) and covers 0.76 to 15 ${\mu}m$ region with 0.2 to 0.5 $cm^{-1}$ resolution. GPM is a joint project with NASA and will carry two instruments. JAXA will develop DPR (Dual frequency Precipitation Radar) which is a follow on of PR on TRMM. Another project is EarthCare. It is a joint project with ESA and JAXA is going to provide CPR (Cloud Profiling Radar). Discussions on future Earth Observation programs have been started including discussions on ALOS F/O.