• Title/Summary/Keyword: DPE

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Design Space Exploration of Many-Core Processors for Ultrasonic Image Processing at Different Resolutions (다양한 해상도의 초음파 영상처리를 위한 매니코어 프로세서의 디자인 공간 탐색)

  • Kang, Sung-Mo;Kim, Jong-Myon
    • The KIPS Transactions:PartA
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    • v.19A no.3
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    • pp.121-128
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    • 2012
  • This paper explores the optimal processing element (PE) configuration for ultrasonic image processing at different resolutions ($256{\times}256$, $768{\times}1,024$, and $1,024{\times}1,280$). To determine the optimal PE configuration, this paper evaluates the impacts of a data-per-processing element (DPE) ratio that is defined as the amount of image data directly mapped to each PE on system performance and both energy and area efficiencies using architectural and workload simulations. This paper illustrates the correlation between DPE ratio and PE architecture for a target implementation in 130nm technology. To identify the most efficient PE structure, seven different PE configurations were simulated for ultrasonic image processing. Experimental results indicate that the highest energy efficiencies were achieved at PEs=1,024, 4,096, and 16,384 for ultrasonic images at $256{\times}256$, $768{\times}1,024$, $1,024{\times}1,280$ resolutions, respectively. Furthermore, the maximum area efficiencies were yielded at PEs=256 ($256{\times}256$ image) and 4,096 ($768{\times}1,024$ and $1,024{\times}1,280$ images), respectively.

Architecture Exploration of Optimal Many-Core Processors for a Vector-based Rasterization Algorithm (래스터화 알고리즘을 위한 최적의 매니코어 프로세서 구조 탐색)

  • Son, Dong-Koo;Kim, Cheol-Hong;Kim, Jong-Myon
    • IEMEK Journal of Embedded Systems and Applications
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    • v.9 no.1
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    • pp.17-24
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    • 2014
  • In this paper, we implement and evaluate the performance of a vector-based rasterization algorithm for 3D graphics by using a SIMD (single instruction multiple data) many-core processor architecture. In addition, we evaluate the impact of a data-per-processing elements (DPE) ratio that is defined as the amount of data directly mapped to each processing element (PE) within many-core in terms of performance, energy efficiency, and area efficiency. For the experiment, we utilize seven different PE configurations by varying the DPE ratio (or the number PEs), which are implemented in the same 130 nm CMOS technology with a 500 MHz clock frequency. Experimental results indicate that the optimal PE configuration is achieved as the DPE ratio is in the range from 16,384 to 256 (or the number of PEs is in the range from 16 and 1,024), which meets the requirements of mobile devices in terms of the optimal performance and efficiency.

Pupal Drone Extracts for Anti-wrinkle and Skin-lightening Materials (수벌번데기 추출물의 주름개선 및 미백효과 구명)

  • Kim, Jung-Eun;Kim, Do-Ik;Koo, Hui-Yeon;Kim, Hyeon-Jin;Kim, Seong-Yeon;Lee, Yoo-Beom;Moon, Jae-Hak;Choi, Yong-Soo
    • Journal of Life Science
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    • v.30 no.5
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    • pp.428-433
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    • 2020
  • In this study, we created pupal stage extracts of Apis mellifera L. drones for use in cosmetic materials. The effect of the drone pupae extract (DPE) on HDF cells was assessed for analysis of anti-wrinkle activity by collagen or collagenase gene expression, and the skin-lightening effect was studied by in vitro tyrosinase inhibition and B16F10 melanoma assay; the two cells were found to be non-cellular when the concentration of DPE was 100 ㎍/ml. Albutin concentration (positive control) in the whitening test was set at a capacity of 100 ug/ml and m-melanocyte stimulating hormone (α-MSH). A melanin-producing induction material was set at a concentration of 100 nM, and the expression of collagen type I and MMP1 collagenase was measured using HDF cells. MMP1 expression was seen to reduce in a concentration-dependent manner in treatment with DPE. Inhibiting melanin generation with B16F12 cells indicated a tendency to decrease in the DPE treatment group. Both L-Tyrosine and L-DOPA as DPE were used in an in vitro tyrosinase induction test to demonstrate the effects of tyrosinase suppression on concentrations. The higher the concentration of DPE, the greater the wrinkle reduction and whitening effect. In conclusion, it was found that DPE is an effective smoothing and whitening material by increasing collagen generation and inhibiting collagenase expression and reducing melanin production.

TINA-C DPE 플랫폼

  • Park, Sung-Won;Sun, Gyung-Seop;Ahn, Soon-Sin
    • Communications of the Korean Institute of Information Scientists and Engineers
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    • v.14 no.1
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    • pp.10-23
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    • 1996
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Performance Measurement and Analysis of Intranet using DPE-based Performance Management System

  • Kim, Seoung-Woo;Kim, Chul;Shin, Jae-Kwang;Kim, Young-Tak
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.4C
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    • pp.282-294
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    • 2002
  • The modern telecommunication networks are composed of various network-type and are managed by various management technologies, such as TMN, SNMP, TINA etc. Furthermore, the network user's needs of real-time multimedia services are rapidly increasing. In order to guarantee the user-requested quality-of-service(QoS) and keep the network utilization at maximum, it is required to manage the network performance continuously after the network is deployed. The performance management function should provide the useful information for the network expansion and the capacity reallocation in the future. In this paper, we propose a DPE-based performance management architecture for the integrated management of the heterogeneous network elements with TMN and SNMP. We propose an approach to provide the Intranet traffic monitoring and analysis function using layered network management concept and distributed processing technology. The proposed architecture has been designed and implemented based on multiprocess and multithread structure to support concurrent processing. To manage the traffic according to the Intranet service categories, we implemented an ITMA(Intelligent Traffic Monitoring Agent) with packet capture library. With the proposed architecture, we could measure and analyze the real Intranet traffic of Yeungnam University.

Expression, Purification, and Crystallization of D-Psicose 3-Epimerase from Agrobacterium tumefaciens

  • Kim Kwang-Soo;Kim Hye-Jung;Oh Deok-Kun;Cheong Jong-Joo;Rhee Sang-Kee
    • Journal of Microbiology and Biotechnology
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    • v.16 no.4
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    • pp.647-650
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    • 2006
  • D-Psicose 3-epimerase (DPE) catalyzes the interconversion of D-fructose to D-psicose by epimerizing the carbon-3 position. The DPE from Agrobacterium tumefaciens was cloned and expressed in Escherichia coli. The expressed enzyme was purified by affinity chromatography on an IMAC, gel filtration chromatography on a Sephacryl S-300 HR, and anion-exchange chromatography on a RESOURCE Q. The molecular mass of the purified enzyme was estimated to be about 135 kDa by Superdex 200 gel filtration chromatography, corresponding to a homotetramer. The enzyme produced crystals suitable for X-ray diffraction to a $2.0{\AA}$ resolution at 100 K. The crystals were found to belong to the orthorhombic space group $P2_12_12_1$, with unit-cell parameters a=102.4, b=113.0, and $c=131.8{\AA}$. In addition, the calculated packing parameter $(V_m)$ was $2.79{\AA}^3/Da$, the solvent content was 55.92%, and an asymmetric unit consisted of four monomers.

Synthesis and Characterization of Aromatic Polyamideamide-imide and Polyamide-imide copolymers

  • Kim, Sang-Hern
    • Journal of the Korean Applied Science and Technology
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    • v.25 no.2
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    • pp.144-150
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    • 2008
  • The polyamide-amide-imide (PAAI) was synthesized by reacting 4,4'-diaminobenzanilide (DBA) with trimellitic anhydride chloride using a two-stage heating. The precursor of polyamide-acids was formed at first stage and followed by the formation of imide of PAAI. Two polyamide-imides (PAIs) were prepared from benzidine (BZ) or 4,4'-diaminodiphenylether (DPE) with trimellitic anhydride chloride. These three polymers had glass transition temperature in the temperature range of $240-250^{\circ}C$. X-ray data were obtained on thin film specimens cured at $250^{\circ}C$. There was a minimal kind of short-range order consisting of the most probable distances between neighboring chains. The average segmental spacing of short-range order decreased in the order of polymers obtained from 4,4'-diaminobenzanilide (DBA), polyamide-imide, and 4,4'-diaminodiphenylether (DPE). The imidization of three polyamide-imides was confirmed by $^{15}N$ MAS NMR and FT-IR spectroscopy. $^{15}N$ NMR spectrum of cured polyamide-imide showed imide $^{15}N$ peak, thereby providing an evidence for the imidization of three polyamide-imides.

Effects of Whitmania pigra on the expressions of cytokine genes in human THP-1 cells (수질(水蛭)이 THP-1세포의 사이토카인 유전자 발현에 미치는 영향)

  • Kim, Hyun-Ji;Kim, Gyung-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.1
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    • pp.19-34
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    • 2013
  • Objective : This study was performed to evaluate the effect of immune reaction inductive substances such as PMA, LPS, DPE, DNCB and WP, the whitman pigra extracting substance at simultaneously on the translocation of $NF{\kappa}B$ towards to the nucleus and the mRNA expression patterns of various cytokine genes in THP-1 cells, monocytes of human. Methods : To analyze the cytokine genes expressions, the RT-PCR method was used, and measuring TNF-${\alpha}$ that had been secreted during cell culture by the ELISA method. The morphological changes were observed during THP-1 cell by a scanning electron microscope and the quantitative distribution of $NF{\kappa}B$ in the cell that was analyzed through immunocytochemistry and a confocal microscopy. Results : WP showed different influences onto the mRNA expression patterns of cytokine genes with PMA, LPS. DPE and DNCB according to the types of immune inductive substances in the THP-1 cells. Upon treating PMA and DPE on the THP-1 cells at the same time or either additionally treating WP thereon, the movement of $NF{\kappa}B$ increase towards the nucleus from cell cytoplasm was able to be observed. The expressions of IL-$1{\alpha}$ and IFN-${\gamma}$ induced by PMA and PMA+DNCB were suppressed by WP while the expression of TGF-${\beta}$ was promoted. Regarding the secretion pattern of TNF-${\alpha}$ according to the treatment of PMA, its secretion amount was incredibly increased by concurrent treatment of WP, however, in case of co-treatment of WP with PMA and DNCB, it was found that the secretion amount of TNF-${\alpha}$ decreased. Conclusions : In this study, the WP extracting substance was confirmed that it had an influence on expression patterns of cytokine genes according to the actions of a variety kinds of immune reaction inductive substances treated on the THP-1 cells. Especially, WP co-treatment with PMA and DNCB was suppressed the expression of inflammatory cytokines, such as IL-$1{\alpha}$, IFN-${\gamma}$ and TNF-${\alpha}$.

A Clinical Study of Acute Carbon Monoxide Intoxication (급성 일산화탄소 중독증 환자의 임상적 고찰)

  • Choi, Kyong-Chan;Park, Mee-Yeung;Hah, Jung-Sang;Byun, Yeung-Ju;Park, Choong-Suh
    • Journal of Yeungnam Medical Science
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    • v.8 no.1
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    • pp.86-97
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    • 1991
  • To obtain the basic data of prognosis of acute carbon monoxide(CO) intoxication, one hundred and sixteen cases of CO intoxication defined by carboxyhemoglobin(COHb) and admitted via emergency room of Yeungnam University Hospital from Oct. '85 to April' 89 have been clinically analyzed and evaluated, including delayed postanoxic encephalopathy(DPE) and the following results were obtained. 1. The ratio of male to female was 1:1.5 and mental state was drowsy mostly(26.2% of 116 cases) 2. The more disturbed the mental state, the more decreased was the arterial pH and $PaCO_2$, which may be the result of metabolic acidosis. 3. The early laboratory findings in patients of CO intoxication were as follows : leukocytosis-65.5%, increase of hematocrit-23.3%, hyperglycemia-19.8%, increase of GPT-19.8% increase of creatinine-0.9%, and glucosuria-12.1%. 4. The early findings of EKG were abnormal in 35.3% : change of rhythm-25.0%, abnormal ST segment-15.5% (change of rhythm and abonormal ST segment-5.2%) but the conduction disorder was not present. 5. The abnormal EEG above mild degree was 93.1%, of which moderate was most frequent(80.2%). 6. The incidence of DPE was 7.8% among all admitted CO patients. DPE cases had long duration of exposure time(8 hours), severe leukocytosis(20,000) and an abnormal EEG(MA).

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Effects of Cryptotympana pustulata on the expression of cytokine genes in human monocytes of THP-1 (선퇴가 인간의 THP-1 단핵구에서 사이토카인 유전자 발현에 미치는 영향)

  • An, Jong-Hyun;Kim, Kyung-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.1
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    • pp.94-110
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    • 2010
  • Objective : This study was performed to evaluate the effect of immune reaction inductive substances such as phorbol-myristate-acetate(PMA), lipopolysaccharide(LPS), dermato-phagoides pteronyssus crude extract(DPE), dinitrochloro-benzene(DNCB) and Cryptotympana pustulata(CP), the Cryptotympana pustulata extracting substance at simultaneously on the translocation of nuclear factor-kappa B(NF-${\kappa}B$) towards to the nucleus and the mRNA expression patterns of various cytokine genes in Human acute monocytic leukemia cell line(THP-1 cells), monocytes of human. Experiment : To analyze cytokine genes expression patterns, the RT-PCR method was used, measuring tumor necrosis factor(TNF)-$\alpha$ that had been secreted during cell culture in the ELISA method. The morphological change in the cell observed during THP-1 cell culture was observed using a scanning electron microscope (SEM) and the quantitative distribution in the cell NF-${\kappa}B$ was analyzed through immunocytochemistry and a confocal microscopy. Result : CP showed different influences onto the mRNA expression patterns of cytokine genes with PMA, LPS. DPE and DNCB according to the types of immune inductive substances in the THP-1 cells. The expressions of inter-leukin(IL)-10, interferon(INF)-$\gamma$, TNF-$\alpha$ and monocyte chemoattractantant protein(MCP)-1 induced by PMA were suppressed by CP while the expression of transforming growth factor(TGF)-$\beta$ was promoted. Regarding the secretion pattern of TNF-$\alpha$ according to PMA processing, its secretion amount was increased by CP concurrent processing, in case of processing CP onto PMA and LPS, We discovered that the secretion amount of TNF-$\alpha$ was increased. Upon processing PMA and LPS on the THP-1 cell strain at the same time or either additionally processing CP thereon, the movement increase towards the nucleus from the NF-${\kappa}B$ cell cytoplasm, a transcription factor was able to be observed. Conclusion : In this study, Cryptotympana pustulata extracting substance was confirmed that it had an influence on expression patterns of cytokine genes according to the actions of a variety kinds of immune reaction inductive substances processed on the monocyte THP-1 cell of humans. Therefore, additional studies as for the immune adjusting function of Cryptotympana pustulata are considered to be able to offer important materials for curing immune abnormal diseases such as atopy dermatitis afterward.