• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2007년도 춘계학술발표대회
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• pp.1229-1232
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• 2007

산업용 감시 제어 시스템이 대용량화, 개방화 되어 감에 따라 시스템 사용자는 시스템을 보다 효율적으로 운용 관리하고자 한다. 이를 위해서는 산업용 감시 제어 시스템의 구조와, 시스템을 구성하는 장치들 간의 통신 네트워크 방식 등에 국제 표준 규격을 적용해야 한다. 본 논문에서는 90년대 후반까지 국내 전력 자동화 통신프로토콜로 많이 사용되었던 HARRIS-6000 프로토콜과 국제 표준 규격에 따라 개발된 DNP(Distributed Network Protocol)3.0을 비교 분석함으로써, 효율적으로 산업용 감시 제어시스템을 설계하고 운용 관리 할 수 있도록 하고자 한다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2007년도 춘계학술발표대회
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• pp.1209-1212
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• 2007

본 논문에서는 대표적인 산업용 프로토콜인 DNP(Distributed Network Protocol) 3.0과 TETRA(Terrestrial Trunked Radio)의 Gateway System Architecture를 제안한다. TETRA는 재난망 무선통신 기술로써 여러가지 타입의 무선 인터페이스를 제공한다. 이러한 TETRA 기술을 이용해서 원거리에 있는 각 산업용 장비들의 감시 제어를 보다 효율적으로 수행 할 수 있다. 하지만 아직 TETRA의 국내 표준이 이루어지지 않은 상태이기 때문에 본 논문에서는 다양한 산업용 장비와 인터페이스를 할 수 있는 표준을 제공하고자 한다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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• pp.69-71
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• 2001

In this paper, we propose a new communication protocol for remote metering in electric power meters, also define necessary functions for it. The new protocol is based on the international metering protocol. IEC 1107, 62056, DNP 3.0. This protocol has 4-layered architecture, which has physical. data link, lower application, and upper application layers. For each layer, definitions and detailed functions are introduced. The protocol will be used for communication between the meters and the metering computer(or AMR system). KEPCO (Korea Electric Power Corporation) plans to adopt this protocol as a part of a new metering standard for electric power meters.

• 전기학회논문지
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• 제60권4호
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• pp.687-693
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• 2011

In this paper, problems and solutions are proposed for applying IEC 61850 to Distribution Automation System(DAS). Communication protocol integration in power automation system have issued by IEC standards, IEC 61850 of them has researched for applying IEC 61850 to many areas of power system in spite of that it was made for substation automation system. Especially, DAS is just about to apply IEC 61850 by communication network change from serial to ethernet although DNP 3.0 is used. But it's impossible to apply directly IEC 61850 to DAS by difference of environment which unfixed wide area and separated nodes in power distribution system unlike concept of IEC 61850 is made by Substation Automation System(SAS) environment of limited space. Thus, this paper proposed applications of three types which conceptual, practical, and future to consider problems and solutions when apply IEC 61850 to Ethernet based DAS.

• 한국식품과학회지
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• 제12권1호
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• pp.13-17
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• 1980

토양에서 분리(分離)한 Streptomyces 속 중(中) 금속을 함유하는 푸로테아제를 강(强)하게 분비하는 균주 SY 79-1을 선별하여 그 효소학적 성질 몇가지를 조사해 본 결과는 다음과 같다. 1. 본 효소의 최적 pH는 8.0 부근이며 최적 온도는 $45^{\circ}C$였다. 2. 본 효소는 중성(中性) 부근(附近)에서는 비교적 안정하며 열처리에 대해서는 $45^{\circ}C$에서는 안정했으나 $60^{\circ}C$에서는 5분간 처리로 약 70%, 30분간 처리로 완전(完全)히 실활(失活)하였다. $Hg^{++},\;Ag^{+}Cu^{++}$ 등(等)에 의(依)해서 강하게 저해(沮害)되고, $Mg^{++},\;Mn^{++},\;Co^{++}$ 등(等)은 효소 활성을 증진 시켰으며, $Fe^{++},\;Ca^{++},\;Pb^{++},\;Al^{++} 등(等)에는 별 영향을 받지 않았다. 4. 각종 저해제 중(中) EDTA에 의해서는 강하게 저해 되었으나, 2,4-DNP, ${\rho}$-CMB, ${\varepsilon}$-aminocaproic acid thiourea, Na-arsenate, cysteine, oxalate, 구연산에 의해서는 영향을 받지 않았으며, EDTA에 의해서 저해(沮害)된 산소(酸素) 활성(活性)은 $Co_{++}$에 의해서 부활되었다.

• Journal of Nutrition and Health
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• 제51권3호
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• pp.208-214
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• 2018

본 연구는 으뜸도라지추출물의 항알레르기 효과를 조사하기 위해 실시하였다. 으뜸도라지추출물 (50, 100 및 $200{\mu}g/mL$) 처리에 따른 RBL-2H3 비만세포의 세포독성을 조사한 결과 으뜸도라지추출물은 모든 농도에서 세포독성이 관찰되지 않았고, ${\beta}$-hexosaminidase assay를 통해 비만세포의 탈과립 억제능을 평가한 결과 재래종도라지추출물과 비교하여 ${\beta}$-hexosaminidase 억제능이 10배 뛰어남을 확인 하였다. 또한 으뜸도라지추출물은 RBL-2H3 비만세포에서 탈과립 후 유리되는 대표물질인 IL-4, $TNF-{\alpha}$, $PGE_2$ 및 $LTB_4$의 생성 분비를 현저히 감소시켰고, 이러한 효과는 재래종도라지와 비교하여 월등한 것으로 나타났다. 이상의 결과는 으뜸도라지추출물이 알레르기 반응을 효과적으로 억제함을 제시하며 향후 항알레르기 기능성 소재로 개발 가능성이 있음을 나타낸다.

• 약학회지
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• 제38권2호
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• pp.114-122
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• 1994

A study on the absorption mechanism of cefixime(CF), an oral ${\alpha}-amino$ group deficient cephalosporin antibiotic, has been undertaken through the rat jejunum and nasal cavity using an in situ simultaneous perfusion technique developed in our laboratory. CF was well absorbed in the jejunum and nasal cavity of rats at pH 5.0, but not at pH 7.0. CF absorption was studied over four orders of magnitude in concentration to determine saturability. Disappearance of CF in the perfusate followed first-order kinetics at all tested concentrations. The apparent first-order absorption rate constant was found to be dependent on the concentration over the range of $0.1\;mM{\sim}3\;mM$ in the jejunum and nasal cavity of rats. Inhibitors were added to determine the competitive inhibition of CF absorption. The presence of L-tyrosine, L-phenylalanine, alanine-alanine, glycine-glycine and cefadroxil produced the significant inhibition of CF absorption in the nasal cavity and jejunum. However, there was no evidence of the inhibition in the presence of cefazolin. In addition, The CF absorption in the nasal cavity and jejunum was inhibited significantly by ouabain and 2,4-dinitrophenol(DNP). This study suggested that CF is absorbed across the rat nasal cavity and jejunum by carrier-mediated transport mechanism and energy consuming system.

• 대한약침학회지
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• 제10권3호
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• pp.37-46
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• 2007

Objectives We studied on anti-allergic effects of Ganoderma lucidum herbal acupuncture(GHA) and Ganoderma lucidum extract(GE). Methods In vivo, Animals were herbal-acupunctured GHA at both B13s three times for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylatic shock using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase release, IL-4 and TNF-a from RBL-2H3 cells, and nitric oxide from Raw264.7 cell after treatment of GE of various concentrations. Results In vivo, GHA pretreatments at both B13s inhibited compound 48/80-induced active systemic anaphylatic shock. Passive cutaneous anaphylaxis were inhibited by GHA10 and OP. In vitro, $0.1\;{\sim}\;2%$ GE treatments were not affect on cell viability and inhibited b-hexosaminidase release, IL-4, TNF-a and nitric oxide. Conclusions These results suggest that GHA and GE may be beneficial in the inhibition of allergic inflammatory response.

• 대한약침학회지
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• 제15권4호
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• pp.32-41
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• 2012

Objectives: Rehmannia glutinosa pharmacopuncture solution (RGPS) was investigated to determine both its anti-allergic inflammatory effects on mast cells and its detailed mechanism of actions. Methods: We investigated whether RGPS suppress cytokines, enzymes, $Fc{\varepsilon}RI$ expression and $Fc{\varepsilon}RI$-mediated signaling in RBL-2H3 cells stimulated with anti-DNP IgE/DNP-HSA. The suppressive effects of RGPS on the levels of cytokines such as IL-$1{\beta}$, IL-6 and GM-CSF were measured using emzyme-linked immunospecific assay (ELISA). The mRNA expression levels of cytokines, enzymes (HDC2, COX-1, COX-2 and 5LO) and $Fc{\varepsilon}RI$ ${\alpha}{\beta}{\gamma}$ subunits were measured using reverse transcription polymerase chain reaction (RT-PCR) method. The activation of $Fc{\varepsilon}RI$-mediated signaling was examined using Western blot analyses. Results: RGPS suppressed production of proinflammatory cytokines (IL-$1{\beta}$, IL-6, and GM-CSF) in stimulated RBL-2H3 cells significantly (p < 0.05). RGPS also suppressed mRNA expression of inflammatory enzymes (HDC2, COX-1, COX-2, 5LO). In addition, mRNA expression levels of $Fc{\varepsilon}RI{\alpha}$, $Fc{\varepsilon}RI{\beta}$and $Fc{\varepsilon}RI{\gamma}$ were lowered by treatment with RGPS. Finally, RGPS prevented phosphrylation of Lyn, Syk, LAT, Gab2, PLC ${\gamma}1/2$, PI3K, Akt, cPLA2 and $I{\kappa}B{\alpha}$. Conclusions: RGPS effectively suppresses mast cell activations such as degranulation and inflammatory response via down-regulation of the $Fc{\varepsilon}RI$-mediated signaling pathways in IgE/Ag-stimulated mast cells.

• 전기학회논문지P
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• 제59권1호
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• pp.35-39
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• 2010

The IT project for power plants initiated domestically in 2005 necessitates the power equipment facility and the controllers for those to be sufficiently adaptable for automation system for power substations. This implies that the power plants using power equipments must be developed to satisfy the IEC61850 standards. The IEC61850 communication standards that all power equipment and facility and controllers installed in automation system for power substations must follow has had its Parts 3 and Part 4 established as international standard in January 2002 and Part 10 in May 2005, the last to become international standard. Hence all separate parts of the original IEC61850 standard came to be established as international standards. As a consequence, after 2005, in most power substations around the world the IEC61850 standard is being applied and the prominent makers are geared towards manufacturing products to the IEC61850 standard. The IEC61850 is being recognized as an essential standard that must be applied to not only power substations but for automation of power systems and communication systems. In this research, the Gateway device that connects current SCADA system and IEC61580 based system has been domesticated with Korea‘s own technology and extensive testing was carried out in order to obtain confidence in its performance.