• 한국산업융합학회 논문집
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• 제7권2호
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• pp.207-213
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• 2004

This paper describes the development of Behind-Tape-Reader (BTR) type DNC system using CYBER 180-830 as a central computer and IBM PC-AT cell control computer and NC lathe with FANUC 5T NC controller. In this system, the connection between central computer and cell control computer is done via RS-232C serial interface board, and that between cell control computer and FANUC 5T controller is done via parallel interface board. The software consists of two module, central computer communication module for NC program downloading and status uploading, NC machine running module for NC operating.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1999년도 춘계학술대회 논문집
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• pp.69-74
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• 1999

This paper aims to DNC application of car seat cushion die. DNC systems are consist of CAD(CATIA1, CAM(Z-MASTER, OMEGA) software and CNC milling machine. CAM software is purpose to G-code generation for CNC programming. Then CAM software and CNC milling machine are connect to RS-232-C cable for networking.

• 융합신호처리학회 학술대회논문집
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• 한국신호처리시스템학회 2000년도 하계종합학술대회논문집
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• pp.137-140
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• 2000

DNC(Direct Numerical Control) Network을 위한 프로그램을 효율적으로 하기 위해 현재 많은 시스템들이 개발되어 사용되고 있다. 그러나 이 시스템들은 원거리 상의 컴퓨터와 머시닝 센터의 제어기 간의 상호 연결이 원만하지 않아 작업에 비효율적인 면이 있고, 또 머시닝 센터에서의 데이터 송ㆍ수신에서 일어나는 오류 문제에 대한 시스템으로의 적절한 대처를 할 수가 없다는 문제점이 있다. 그래서, 본 논문에서는 DNC Network을 통해 머시닝 센터 제어기에서 컴퓨터의 데이터를 오류 없이 수신 가능한 데이터 원격 제어 시스템을 새로이 구성하였다. 이 데이터 원격 제어 시스템의 주요 장점으로는 기존에 일방향으로 구동되어지던 머시닝센터와 컴퓨터간의 Communication을 머시닝 센터에서 운영자가 자유로이 접근하여 컴퓨터에 저장된 NC 가공 데이터 호출과 송출이 자유롭고, 컴퓨터와 공작기계간의 상호 대화가 없이도 NC 공작기계 상에서 원격 제어(Remote Control)가 가능하다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.219-224
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• 2016

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver making up more than 80 percent of cases. It is known to be the sixth most prevalent cancer and the third most frequent cause of cancer related death worldwide. Epigenetic regulation constitutes an important mechanism by which dietary components can selectively activate or inactivate target gene expression. The miR-34 family members including mir-34a, mir-34b and mir-34c are tumor suppressor micro RNAs, which are expressed in the majority of normal tissues. Several studies have indicated silencing of miR-34 expression via DNA methylation in multiple types of cancers. Bioactive nutrients like curcumin (Cur) have excellent anticarcinogenic activity and minimal toxic manifestations in biological systems. This compound has recently been determined to induce epigenetic changes. However, Cur is lipophilic and has a poor systemic bioavailability and poor absorption. Its bioavailability is increased through employing dendrosome nanoparticles. The aim of the current study was to investigate the effect of dendrosomal nanocurcumin (DNC) on expression of mir-34 family members in two HCC cell lines, HepG2 and Huh7. We performed the MTT assay to evaluate DNC and dendrosome effects on cell viability. The ability of DNC to alter expression of the mir-34 family and DNA methyltransferases (DNMT1, DNMT3A and 3B) was evaluated using semi-quantitative and quantitative PCR. We observed the entrance of DNC into HepG2 and Huh7 cells. Gene expression assays indicated that DNC treatment upregulated mir34a, mir34b and mir34c expression (P<0.05) as well as downregulated DNMT1, DNMT3A and DNMT3B expression (P<0.05) in both HepG2 and Huh7 cell lines. DNC also reduced viability of Huh7 and HepG2 cells through restoration of miR-34s expression. We showed that DNC could awaken the epigenetically silenced miR-34 family by downregulation of DNMTs. Our findings suggest that DNC has potential in epigenetic therapy of HCC.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1990년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 26-27 Oct. 1990
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• pp.167-169
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• 1990

This paper describes the DNC technology as a partial approach to a achieving dr system integration of NC machines. The study deals with development of a system to unify NC machines by utilizing a DNC. The system is provided to have the potential of offering ft environment and application fundamentals to construct factory automation.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3917-3922
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• 2015

Curcumin, a lipid-soluble compound extracted from the plant Curcuma Longa, has been found to exert immunomodulatory effects via macrophages. However, most studies focus on the low bioavailability issue of curcumin by nano and microparticles, and thus the role of macrophages in the anticancer mechanism of curcumin has received little attention so far. We have previously shown the potential biocompatibility, biodegradability and anti-cancer effects of dendrosomal curcumin (DNC). In this study, twenty-seven BALB/c mice were equally divided into control as well as 40 and 80 mg/kg groups of DNC to investigate the involvement of macrophages in the antitumor effects of curcumin in a typical animal model of metastatic breast cancer. At the end of intervention, the tumor volume and weight were significantly reduced in DNC groups compared to control (P<0.05). Histopathological data showed the presence of macrophages in tumor and spleen tissues. Real-time PCR results showed that DNC increased the expression of STAT4 and IL-12 genes in tumor and spleen tissues in comparison with control (P<0.05), referring to the high levels of M1 macrophages. Furthermore treatment with DNC decreased STAT3, IL-10 and arginase I gene expression (P<0.05), indicating low levels of M2 macrophage. The results confirm the role of macrophages in the protective effects of dendrosomal curcumin against metastatic breast cancer in mice.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권3호
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• pp.837-852
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• 2021

Recurrent neural network (RNN) architectures have been used for language modeling (LM) tasks that require learning long-range word or character sequences. However, the RNN architecture is still suffered from unstable gradients on long-range sequences. To address the issue of long-range sequences, an attention mechanism has been used, showing state-of-the-art (SOTA) performance in all LM tasks. A differentiable neural computer (DNC) is a deep learning architecture using an attention mechanism. The DNC architecture is a neural network augmented with a content-addressable external memory. However, in the write operation, some information unrelated to the input word remains in memory. Moreover, DNCs have been found to perform poorly with low numbers of weight parameters. Therefore, we propose a robust memory deallocation method using a limited retention vector. The limited retention vector determines whether the network increases or decreases its usage of information in external memory according to a threshold. We experimentally evaluate the robustness of a DNC implementing the proposed approach according to the size of the controller and external memory on the enwik8 LM task. When we decreased the number of weight parameters by 32.47%, the proposed DNC showed a low bits-per-character (BPC) degradation of 4.30%, demonstrating the effectiveness of our approach in language modeling tasks.

• 대한안전경영과학회지
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• 제5권2호
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• pp.87-98
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• 2003

With the development of CNC(Computer Numerical Control) and communication technology, the connotation and functions of Distributed Numerical Control have been greatly enlarged. In this study, we develop and implement a Distributed Numerical Control system that has real time and multi-tasking operation capability for the machining cell with various NC(Numerical Control) and CNC machines. With the consideration of economy, generalization and extension, this system is interfaced with Shop Floor Control System, Machine Control System and Tool Preparation System using advanced networking method. In the implementation phase, we use the ORACLE DBMS (Database Management System) as the DBMS and Microsoft Visual C++ as the programming tools.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1991년도 추계학술대회 논문집
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• pp.194-201
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• 1991

일반적으로 금형공업은 전형적인 중소기업형 공업으로 계획생산보다는 주문 생산방식으로 운영되고 있으며 부가 가치가 높은 산업이다. 또한 업태가 다양하고 산업구조의 선진화에 비례하여 기업체 수가 증가하는 추세이며 고정밀도, 고숙련도를 요하는 고도의 기술 집약적 산업이다. 정밀도의 향상, 인력절감, 자동화와 함께 금형 공장내의 제한된 자원을 효율적으로 이용하고 공장자동화를 촉진하기 위한 각 부문별 자동화 시스템, 컴퓨터 시스템을 정보 Network 로 접속해 공장내 제반관련자료를 유효하게 활용할 수 있는 Total System으로서의 공장운영 시스템의 도입ㆍ필요성이 대두되고 있다.(중략)

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1992년도 추계학술대회 논문집
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• pp.228-232
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• 1992

The integrated management system IMMC system) is developed for machining, measuring and checking by using IBM-PC under Borland C $\^$++/ environment. MMC system consists of following systems : DNC system, MascMC system (for measuring and checking) and MascCAM system : DNC system, MascNC system (for measuring and checking) and MascCAM system (for CAM). And some other modules support MMC system for practical usages. A vertical machining center equipped with FANUC 0MC is used for experiments. Feasibility of the system is confirmed by a large amount of experiments.