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Immunomodulating Activity of BL18 (Ganshu) Acupuncture on the Experimental Liver Metastasis Model of Mice

  • Kim, Myoung-Dong;Kim, Sung-Hoon;Lee, Soo-Jin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.3
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    • pp.760-764
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    • 2007
  • We investigated that the immunomodulating activity of BL18 (Ganshu) acupuncture on the experimental liver metastasis model of mice. NA (non-acupoint)- and BL18-treatment enhanced the mitogenic activity of BALB/c whole splenocytes induced by various mitogenic stimuli. Acupuncture treatment tended to increase splenocytes differentiation even though did not show significance. Acupuncture treatment caused a marked increase of production of Th1 cytokine (IFN-${\gamma}$) and Th2 cytokine (IL-4) by splenocytes and IL-12 and IFN-Y by macrophages. The increase of cytokine production on BL18-treated group was more pronounced compared to NA-treated group. The liver weight of NA- and BL18-treated group decreased compared to tumor group, but did not showed significant differences.

Evolutionary Theory Of Management In Education

  • Moskalenko-Vysotska, Olena;Melnyk, Emiliia;Tovstenko-Zabelin, Serhii;Lehka, Svitlana;Didenko, Maryna;Hrubych, Kostiantyn
    • International Journal of Computer Science & Network Security
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    • v.22 no.1
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    • pp.312-318
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    • 2022
  • The article notes that one of the reasons for the crisis in education was the sharp discrepancy between the emerging new forms and content and the model of macro-management that has developed over the decades. The level of management of the educational system did not emerge as a specific activity characterized by its own mechanisms and processes, just as qualified carriers of this activity - professionals - managers - did not appear. At the same time, there is practically no theoretical and methodological model of the macrolevel of education management, that is, management of the educational system as an integral structure.

Development of Functional Bread with Sea Tangle Single Cell Detritus (SCD) (다시마 Single Cell Detritus(SCD)를 첨가한 기능성 빵의 개발)

  • Bang, Sang-Jin;Choi, Seung-Hwa;Shin, Il-Shik;Kim, Sang-Moo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.10
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    • pp.1430-1437
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    • 2009
  • Functional bread was manufactured with single cell detritus (SCD) of sea tangle. The optimum ingredient formula for SCD bread was determined based on mixture model. Flour and water reduced max weight, strength, hardness and specific loaf volume, whereas the increased SCD reversed the volume change of dough. Flour increased $L^*$ and $b^*$ values of SCD bread, while SCD decreased. Flour and water decreased $a^*$ value, while SCD increased. Max weight, strength, hardness, specific loaf volume, $b^*$ value and water holding capacity (WHC) were linear model on ANOVA table, whereas distance, volume change of dough, $L^*$ and $a^*$ values were nonlinear model. The response constraint coefficient showed that SCD influenced texture of SCD bread more than flour and water did, whereas water influenced the volume change of dough, specific loaf volume and WHC more than flour and SCD did. Moreover, flour influenced color value more than did water and SCD. Distance and $a^*$ value fitted nonlinear model with interaction terms for flour-SCD and water-SCD. Optimum ingredient formula for SCD bread was: flour, 48.25%; water, 30.89%; SCD, 3.86%. Sensory evaluation of SCD bread was a little lower than industrial bread and electrolyzed SCD bread.

The Effects of Housing Values on Housing Satisfaction Model (주거만족도 모델에서의 주거가치의 역할 연구)

  • 양세화
    • Journal of the Korean housing association
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    • v.7 no.2
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    • pp.1-7
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    • 1996
  • This study was designed to examine the effects of housing values on housing satisfaction model. The empirical model of this study was based on the Goulart(1982). Data were collected through questionnaire survey, and the sample consisted of 285 households in Kimhae. Housing values were grouped into four clusters : the health and convenience value, the personal and social value, the location value, and the economic value. The major findings were that 1) the concordance between values and the actual housing conditions contributes significantly to the prediction of housing astisfaction, and 2) the control variables including sociodemographic and economic characteristics and housing values themselves did not directly influence on housing satisfaction.

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Representation of Model Uncertainty in the Short-Range Ensemble Prediction for Typhoon Rusa (2002) (단기 앙상블 예보에서 모형의 불확실성 표현: 태풍 루사)

  • Kim, Sena;Lim, Gyu-Ho
    • Atmosphere
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    • v.25 no.1
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    • pp.1-18
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    • 2015
  • The most objective way to overcome the limitation of numerical weather prediction model is to represent the uncertainty of prediction by introducing probabilistic forecast. The uncertainty of the numerical weather prediction system developed due to the parameterization of unresolved scale motions and the energy losses from the sub-scale physical processes. In this study, we focused on the growth of model errors. We performed ensemble forecast to represent model uncertainty. By employing the multi-physics scheme (PHYS) and the stochastic kinetic energy backscatter scheme (SKEBS) in simulating typhoon Rusa (2002), we assessed the performance level of the two schemes. The both schemes produced better results than the control run did in the ensemble mean forecast of the track. The results using PHYS improved by 28% and those based on SKEBS did by 7%. Both of the ensemble mean errors of the both schemes increased rapidly at the forecast time 84 hrs. The both ensemble spreads increased gradually during integration. The results based on SKEBS represented model errors very well during the forecast time of 96 hrs. After the period, it produced an under-dispersive pattern. The simulation based on PHYS overestimated the ensemble mean error during integration and represented the real situation well at the forecast time of 120 hrs. The displacement speed of the typhoon based on PHYS was closest to the best track, especially after landfall. In the sensitivity tests of the model uncertainty of SKEBS, ensemble mean forecast was sensitive to the physics parameterization. By adjusting the forcing parameter of SKEBS, the default experiment improved in the ensemble spread, ensemble mean errors, and moving speed.

A Database Model for Financial Feasibility Study of Buildings Offered for Sale (분양형 건축물의 재무적 타당성검토를 위한 데이터베이스 모델)

  • Oh Hyun-Suk;Jung Jae-Gwan;Koo Kyo-Jin;Hyun Chang-Taek
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.577-580
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    • 2003
  • The purpose of this study was to make a database model for financial feasibility study of buildings offered for sale which is helpful for improvement of business ability in construction and confidence of a project from a related participant. At first, we studied several thesis and met some professionalist which work for construction and did a first survey for examining latest situation of a feasibility study in construction. As a result, even though feasibility study is important, factors for information management wasn't systemized. So we did a second survey for fixing Factors of the database model. The database model was composed of the factors that we got from the second survey. ER(Entity-Relationship) analysis was used to making it. We expect thar we can get more reasonable information to study financial feasibility study and can diminish risks of project through the database model. So the result of this study was to make a database model for more reasonable financial feasibility study of building offered for sale.

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Effects of omni channel characteristics on consumers' perceived risk, attitude, and intention (옴니채널(Omni Channel) 특성이 소비자들의 지각된 위험과 태도 및 이용의도에 미치는 영향)

  • Hong, Jung-min;Shin, Su-yun
    • The Research Journal of the Costume Culture
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    • v.26 no.3
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    • pp.346-359
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    • 2018
  • Currently, dramatic change had led to the growth of the distribution environment and the retailer's distribution channel. This change had shifted the 'single channel' to 'multi channel', and from 'cross channel' to 'omni channel'. While fashion companies using omni channel are rapidly growing, few research regarding omni channel had been done in academic field. In this study, we examined the influence of omni channel characteristics on consumers' perceived risk as well as consumers' perceived risk toward attitude and intention to use omni channel. We surveyed 696 male and female respondents aged 20 to 40 who lived in Seoul and the metropolitan area. Using AMOS 20.0, factor analysis, reliability analysis, and structural equation model analysis were performed to verify the model of this study. The results were as follows. First, omni channel's instant connectivity, location-based provability, interactivity, and entertainment factors did not decrease impacts on the perceived risk related to privacy and annoyance. Second, omni channel's instant connectivity and entertainment did not increase effects on the perceived financial risk, and location-based provability and interactivity did not increase effect on perceived financial risk. Third, the perceived risk concerning omni channel did not decrease on consumer attitude toward omni channel. Fourth, consumer attitude toward omni channel influenced the intention to use omni channel significantly.

Late-term healing in an augmented sinus with different ratios of biphasic calcium phosphate: a pilot study using a rabbit sinus model

  • Lim, Hyun-Chang;Hong, Ji-Youn;Lee, Jung-Seok;Jung, Ui-Won;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.46 no.1
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    • pp.57-69
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    • 2016
  • Purpose: The aim of this pilot study was to determine the osteoconductivity and dimensional stability of augmented sinuses using different ratios of biphasic calcium phosphate (BCP) in a rabbit sinus model. Methods: Each sinus of New Zealand white rabbits (2.5-3.5 kg) was assigned to one of two groups: BCP with a hydroxyapatite to ${\beta}$-tricalcium phosphate (HA:${\beta}$-TCP) ratio of 70:30 (group TCP30) and BCP with an HA:${\beta}$-TCP ratio of 30:70 (group TCP70). After preparing a window in the antral wall of a sinus, the Schneiderian membrane was elevated, and the applicable material was grafted. A fluorochrome calcein green was injected five days before euthanizing the animals at four months post-surgery. The specimens were analyzed histologically, histomorphometrically, and by using micro-computed tomography (micro-CT). Results: Micro-CT analysis revealed that the total augmented volume and the new bone volume did not differ significantly between the two groups whereas the resorption of materials was greater in the TCP70 group. The trabecular thickness, number, and separation also did not differ significantly between the two groups. Histomorphometrically, the areas of total augmentation, new bone, and residual material, as well as the ratio of new-bone-material contact did not differ significantly between the groups. Histologically, the residual particles were more scattered in the TCP70 group than in the TCP30 group. The fluorescence of the calcein green did not differ notably between the two groups. Conclusions: The osteoconductivity and dimensional stability of the two BCPs with different ratios tested in this study were comparable after four months of healing. Therefore, we conclude that both BCPs show promise as a bone substitute for sinus augmentation.

The Parameter Estimation of WASP Model for Water Quality Prediction (수질예측을 위한 WASP7 모형 매개변수의 추정)

  • Ahn, Seung-Seop;Seo, Myung-Joon;Park, Ro-Sam;Jeong, Khang-Ok
    • Journal of Environmental Science International
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    • v.16 no.5
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    • pp.623-632
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    • 2007
  • The objective of this study is analysis of Andong-Dam lake water quality with water quality model. Model parameters of the WASP applied to Lake Andong-Dam were estimated. The methodology is based on grouping water quality constituents and relevant parameters and successively estimating parameters by a trial-and-error procedure. Water qualify system for modeling consisted of BOD, DO, T-N, T-P. The results of water quality modelling using WASP. T-N was maximum affected by K71C(Organic nitrogen mineralization rate) parameter. T-P was maximum affected by K83C(Dissolved organic phosphorus mineralization) parameter, and It did not show a difference almost from the parameter of others and it omitted. BOD was maximum affected by Temperature parameter, it was visible of the reaction due to the KDC(Deoxygenation rate) in afterwords, and it did not show a difference from the parameter of others and it omitted. DO was maximum affect by Temperature parameter, and It did not show a difference almost from the parameter of others and it omitted. The parameter which it presumes from the this study uses a water quality modeling and Actual value and the result with which it compares, error rate the parameter presumption which is appropriate with 1% interior and exterior is investigated, It will reach and it uses and it will be able to apply to the suitable parameter in water quality modelling of the objective area which can be feeded by it becomes.

A Structural Model for Quality of Life in Individuals with Rheumatoid Arthritis (류마치스성 관절염 환자의 삶의 질에 대한 구조 모형)

  • 오현수;김영란
    • Journal of Korean Academy of Nursing
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    • v.27 no.3
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    • pp.614-626
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    • 1997
  • The main purposes of the study were to develop and test a model which explains the dynamic relationship among factors reported as affecting to the quality of life of individuals with rheumatoid arthritis and to examine the relationship between self-help response and quaility of life. Data for the study were collected from March 1996 to December 1996 from 153 female patients who regularly visited a clinic for people with rheumatism. The patients were introduced to the investigators by nurses who worked at that clinic, and then the investigator interviewed the patients for 30 to 40 minutes to collect the data. Instruments used in the study were modified self-report questionaires from the ones which were already developed in previous studies or from related literature. Data analysis were performed using LISREL(Lineal Structural Relations) 8 program to test whether the proposed hypothesized model fit the collected data. To test the fitablity of the hypothesized model both a general fit measure and a detailed fit measure were used. Based on the test results from the various fit measures, the hypothesized model was found to be well suited to the real data. As characteristics related to illness becomes severe, the feasibility for these characteristics leading to the perception of uncertainty about the illness tend to increase, but, the direct effects from the illness characteristics(such as level of physical symptoms, sense of social-psychologic change, limitations of action) as they are related to the other intrinsic variables (self-efficacy or self-help behavior and quality of life), were found to be not significant. It was found that uncertainty had a direct effect on self-efficacy but did not have a direct effect on self-help behavior or quality of life. Also, it is noted that self-efficacy had a positive effect on self-help behavior and quality of life and there was a bilateral relationship between self-efficacy and self-help behavior. Lastly, the hypothesis proposed from the theoretical model in this study was supported basis of the results that self-help behavior provides both direct and positive effects to quality of life. Particularity, since a bilateral relationship was also found between self-help behavior and quality of life in the modified model, as self-help behavior increased, so did quality of life. And, reversely, as quality of life increased, so did self-help behavior. In conclusion, the results of this study suggest that focusing on both acquirement and reinforcement of adjustment factors or self-help behavior is more efficient than focusing on the characteristics of illness in establishing the stategies for improving quality of life of individuals with rheumatoid arthritis.

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