• 대한한의학방제학회지
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• 제22권2호
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• pp.63-76
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• 2014

Objectives : This study investigated the improvement effects of Pakistani (DF-a) and Chinese Ephedra herba-containing Gangjihwan (DF-b) on obesity in a high fat diet-fed obese mouse model. Methods : Eight-week-old C57BL/6N mice were divided into four groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF-a and DF-b groups given a high fat diet with DF-a (80 mg/kg), and DF-b (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : 1. Body weight gain and fat mass were significantly decreased in DF-a and DF-b groups compared with control. The extent of decreases was eminent in DF-a group. 2. Feeding efficiency ratio and circulating leptin concentration were significantly decreased in DF-a and DF-b groups compared with control, whereas circulating adiponectin concentration was increased in DF-a and DF-b groups compared with control. 3. Consistent with their effects on body weight gain and fat mass, circulating concentrations of triglyceride, glucose and insulin were decreased in DF-a and DF-b groups compared with control. 4. The size of adipocytes were decreased by DF-a and DF-b compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF-a and DF-b decreased the number of large adipocytes. 5. Consistent with their effects on body weight gain, liver fibrosis was reduced in DF-a and DF-b groups compared with control. Conclusions : In conclusion, these results suggest that DF-a and DF-b not only decrease feeding efficiency ratio, plasma leptin concentration, and blood anti-obesity biomarkers, but also reduce fat mass, contributing to the improvement of obesity. DF-a and DF-b also inhibit liver fibrosis. In addition, these effects were similar between Pakistani Ephedra herba and Chinese Ephedra herba-containing Gangjihwan.

• 대한본초학회지
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• 제29권2호
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• pp.47-54
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• 2014

Objectives : This study was undertaken to verify the effect of Gangjihwan(Di-fatty, DF) composed with Pakistani Ephedra Herba on nonalcoholic fatty liver disease(NAFLD) using high fat diet-fed male mice. Method : Eight-week old C57BL/6N mice were used for all experiments. Standard chow diet-fed mice were used as normal group and high fat diet-fed NAFLD mice were randomly divided into 5 groups: control, atorvastatin, DF(1), DF(2) and DF(3). After 8 weeks, mice were treated with water, atorvastatin(10mg/kg) and DF(40, 80, 160mg/kg) for 8 weeks. And we investigated body weight gain, plasma lipid and glucose metabolism, histological analysis for liver on the mice. Results : Compared with controls, DF-treated mice had very significantly lower body weight gain and lower visceral adipose tissue weight, the magnitudes of which were prominent in DF(3). Consistent with their effects on body weight gain, DF-treated mice had lower blood total cholesterol and triglyceride level compared with controls. Consistent with their effects on body weight gain and blood plasma lipid level, DF-treated mice had lower liver weight and hepatic lipid accumulation of DF-treated groups was significantly decreased than control group. Also Blood plasma AST, ALT and ${\gamma}$-GT concentration were not changed by DF, and these results may indicate DF do not show any toxic effects. Conclusions : These results suggest that DF effectively improves NAFLD. DF reduces liver weight and prevents lipid accumulation of hepatocyte by reducing body weight gain and modulating blood plasma lipid metabolism levels.

• 전기전자학회논문지
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• 제15권1호
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• pp.64-69
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• 2011

본 논문에서는 복호 후 전달(decode-and-forward: DF) 릴레이 시스템에 대한 레일리 페이딩 채널에서의 의사-성능 분석 기법을 제안하였다. 우선, 각 릴레이가 복호 오류 유무에 상관없이 전송하는 경우에 대한 성능분석을 릴레이 노드단의 오류 사건을 기반으로 유도한다. 분석된 성능 분석 결과를 통하여 각 릴레이 단의 복호 오류가 수신 SNR 및 평균 오류율 성능 저하를 야기할 수 있음을 확인한다. 또한 제안된 분석 기법을 복호 오류가 없는 경우에만 전송하는 SDF의 경우로 확장함으로써 제안된 분석 기법이 DF 릴레이 시스템에 대한 일반적인 성능 분석 기법임을 확인한다. 그리고 제안된 분석기법의 정확성은 모의실험을 통하여 비교 검증되었다.

• 한국광학회지
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• 제13권1호
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• pp.65-69
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• 2002

불소원자(F)와 D$_2$ 기체 발열반응에 의해 레이저 이득매질인 DF 여기분자를 생성시키는 구조의 연속발진형 불화중수소 (DF)화학 레이저를 설계, 제작하고 발진 실험을 수행하였다. 불소원자는 F$_2$ 기체와 H$_2$ 기체를 연소시켜 생성시키고, 불소원자를 초음속 노즐을 통과시킨 직후에 D$_2$ 기체를 분사하여 형성된 DF 여기분자 초음속 흐름을 활성 매질로 사용하여 레이저를 발진시켰다. 본 연구에서 얻은 레이저 발진 출력은 101W이며, 최적의 유량조건에서 얻은 화학 효율은 5.12%, 비출력은 96.5 J/g이다.

• 한국컴퓨터정보학회논문지
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• 제4권4호
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• pp.218-225
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• 1999

본 연구는 유치원교사의 근무년수별 컴퓨터활용의 차이와 유아를 위한 컴퓨터교육의 실태를 알아보고자 함에 목적을 두고 있다. 이에 따른 연구결과를 보면 유치원교사의 근무년수별 컴퓨터활용도에서는 유의한 차이가 나타났고 ($x^2$=138.486, df=36, p＜.001), 유치원교사의 근무년수별 컴퓨터를 배우고자하는 선호도에서도 유의한 차이가 나타났지만 ($x^2$=519.566, df=64 p＜.001), 유치원교사의 근무년수별 컴퓨터활용프로그램에서는 유의한 차이가 나타나지 않았다. ($x^2$=75.42, df=80, p＞.50) 이는 유치원교사의 컴퓨터활용이 유아를 위한 교육목적위주로 이루지는 것이 아니라 문서관리외에 다른 용도로 이루어짐을 알 수 있다. 따라서 본 연구는 유치원교사의 컴퓨터을 이용한 교육적 활용을 위한 프로그램개발과 연구가 지속적 이루어져야 함을 시사한다.

• 대한지역사회영양학회지
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• 제2권3호
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• pp.281-293
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• 1997

Dietary fiber(DF) intake of teenagers was estimated and the major food sources of fiber were analyzed using three-day food records and data from 365 middle school students in urban, rural and fishing areas. Mean dwily DF intake of males was 9.2$\pm$3.9g in urban, 10.4$\pm$5.4g in rural, and 7.9$\pm$4.0g in fishing areas and the intake of female was 10.6$\pm$5.1g in urban, 10.6$\pm$5.2g in rural, and 7.7$\pm$3.3g in fishing areas. When related to energy intake, female consumed more DF(5.7$\pm$2.5g/1000㎉, 7.0$\pm$3.5g/1000㎉, 4.6$\pm$2.2g/1000㎉, in urban, and rural, fishing areas respectively) than males(4.2$\pm$1.3g/1000㎉, 4.6$\pm$1.5g/1000㎉, 4.4$\pm$2.0g/1000㎉ in urban, rural, fishing respectively). Mean crude fiber(CF) intake of males was 4.1$\pm$1.7g, 4.5$\pm$2.4g, 3.7$\pm$2.4g, and female's intake was 4.7$\pm$1.9g, 4.8$\pm$2.2g, 3.7$\pm$1.9g in urban, rural, and fishing areas respectively. The mean DF : CF ratio for the subjects was 2.2-2.6, indicating that the DF intake is 2-3 times that of CF intakes. The intakes of the two measures of fiber were highly correlated(r=0.7781) . The major food sources for DF were cereals, vegetables and fruits and the percentage contributions of the food groups to the DF intake were 27-37$\%$, 22-30$\%$, and 11.5-19.7$\%$ respectively. The present study indicates that the DF intake of teenagers is considerably lower than the recommended level and they need to consume more DF than that indicated by the present levels. The importance of nutrition education on health and dietary pattern should also be emphasized among teenagers.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제1권1호
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• pp.19-24
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• 1994

Let P be a probability measure on the real line with Lebesque-density f. The usual estimator of the distribution function (≡df) of P for the sample $\chi$$_1$,…, $\chi$$\_$n/ is the empirical df: F$\_$n/(t)=(equation omitted). But this estimator does not take into account the smoothness of F, that is, the existence of a density f. Therefore, one should expect that an estimator which is better adapted to this situation beats the empirical df with respect to a reasonable measure of performance.(omitted)

• 대한화학회지
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• 제29권6호
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• pp.592-598
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• 1985

HF(${\mu}$= 5-7) 및 DF(${\mu}$ = 9-12)의 HF(${\mu}$ = 0) 및 DF(${\mu}$ = 0)에 의한 전체 진동완화 속도 상수 $k_{v,v-1}$을 진동-진동 (V ${\to}$ V) 및 진동-회전, 병진(V ${\to}$ R, T) 두 반응경로를 모두 다 고려하여 단순한 충돌모형과 반고전적 계산방법을 써서 계산하였다. 계산된 속도상수들은 실험값 및 다른 이론들로부터 계산한 값들과 비교적 잘 맞았고, 온도 및 양자수 v가 커짐에 따라 증가하였다. 또한 높은 진동 준위로 들뜬 HF 및 DF의 진동완화과정은 저온에서는 거의 다 V ${\to}$ R, T 경로로 일어나며 온도가 올라감에 따라 V ${\to}$ V 경로의 중요성이 커짐을 보였다.

• 대한한의학방제학회지
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• 제22권2호
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• pp.105-120
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• 2014

Objectives : This study was investigated the improvement effects of Gangjihwan (DF) and combination of Gangjihwan and Gamisochehwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods : Eight-week-old C57BL/6N mice were divided into four groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF and DF+GSH groups given a high fat diet with DF (40 mg/kg), and DF+GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : 1. Body weight gain and fat mass were significantly decreased in DF and DF+GSH groups compared with control. The extent of decreases was eminent in DF+GSH group. 2. Feeding efficiency ratio and circulating concentration of leptin were decreased in DF and DF+GSH groups compared with control. These decreases were significant in DF+GSH group. 3. Consistent with their effects on body weight gain and fat mass, circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF+GSH groups compared with control. 4. The size of adipocytes was decreased by DF and DF+GSH compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF+GSH decreased the number of large adipocytes. 5. Consistent with their effects on body weight gain, liver fibrosis was also improved in DF and DF+GSH groups compared with control. Conclusions : In conclusion, these results suggest that DF and DF+GSH groups decrease feeding efficiency ratio, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain contributing to the inhibition of liver fibrosis. In addition, these effects were more effective in DF+GSH combination group than in DF-only group.

• Animal Bioscience
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• 제36권7호
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• pp.1120-1129
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• 2023

Objective: This study aimed to determine the protective efficacy of Buddha's Temple (BT) extract against tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in Gallus gallus chicken embryo fibroblast cell line (DF-1) and its effects on the cell lipid metabolism. Methods: In this experimental study, Gallus gallus DF-1 fibroblast cells were pretreated with BT 10^-7 for 24 hours, followed by their six-hour exposure to t-BHP (100 μM). Water-soluble tetrazolium salt-8 (WST-8) assays were performed, and the growth curve was computed. The intracellular gene expression changes caused by BT extract were confirmed through quantitative polymerase chain reaction (qPCR). Flow cytometry, oil red O staining experiment, and thin-layer chromatography were performed for the detection of intracellular metabolic mechanism changes. Results: The WST-8 assay results showed that the BT pretreatment of Gallus gallus DF-1 fibroblast cell increased their cell survival rate by 1.08%±0.04%, decreased the reactive oxygen species (ROS) level by 0.93%±0.12% even after exposure to oxidants, and stabilized mitochondrial activity by 1.37%±0.36%. In addition, qPCR results confirmed that the gene expression levels of tumor necrosis factor α (TNFα), TIR domain-containing adapter inducing IFN-beta (TICAM1), and glucose-regulated protein 78 (GRP78) were regulated, which contributed to cell stabilization. Thin-layer chromatography and oil red O analyses showed a clear decrease in the contents of lipid metabolites such as triacylglycerol and free fatty acids. Conclusion: In this study, we confirmed that the examined BT extract exerted selective protective effects on Gallus gallus DF-1 fibroblast cells against cell damage caused by t-BHP, which is a strong oxidative inducer. Furthermore, we established that this extract significantly reduced the intracellular ROS accumulation due to oxidative stress, which contributes to an increase in poultry production and higher incomes.