• Journal of Forest and Environmental Science
• /
• v.40 no.1
• /
• pp.53-63
• /
• 2024

Alnus japonica is indigenous to korea and usually grows in wet lowlands and damp regions in the mountains. Oregonin, is known as a representative compound of the diarylheptanoid mainly found in Alnus species and has been reported to have anti-inflammatory and antioxidant effects. In this experiment, we conducted a study on the presence of orogonin in the native Alnus japonica from the Baekdudaegan mountain range in Korea. We collected a total of 30 samples from Chuncheon, Yangyang, and Jeongseon and conducted experiments. In the HPLC analysis, we confirmed that oregonin was detected in all samples. After the quantitative analysis, samples with the highest content from each region were selected and LC-MS/MS experiments were performed. As a result, the same molecular weight as oregonin, 477.2 m/z, was confirmed in all samples.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.26 no.2
• /
• pp.175-180
• /
• 2012

The purpose of this study is to verify the anti-inflammatory effectiveness of Cheongyeoungkeumyeum(CYK) including seven herbal medicines of that major effectiveness is to clear heat, to relieve fire toxicity and to clear damp-heat. To evaluate anti-inflammatory effectiveness of CYK, we measured the production of reactive oxygen species(ROS), nitric oxide(NO) cyclooxygenase-2(COX-2) and in TNF-${\alpha}$ LPS-activated Raw 264.7 cells. Cell viability was determined by MTT assay. The concentrations of ROS and relative level of NO were measured with DPPH assay and Griess reagent, respectively. COX-2 and TNF-${\alpha}$ were detected by enzyme immuno assay(EIA) and enzyme-linked immunosorbent assay(ELISA). As a result, we found that CYK suppressed LPS-induced ROS and NO production in a dose-dependent manner. Also CYK significantly inhibited LPS-induced COX-2 activity and the release of TNF-${\alpha}$. These results indicate that the CYK may have an anti-inflammatory agent for the treatment of various inflammatory disease.

• The Journal of Korean Medicine
• /
• v.34 no.3
• /
• pp.96-105
• /
• 2013

Objectives: Bi Jeung (비증) is a pain syndrome derivative of pathological patterns of East Asian medicine. The purpose of this study was to develop a self-rated questionnaire for Bi Jeung. Methods: Twelve questionnaire items for Bi Jeung (3 items for the Wind Bi, 5 items for the Cold Bi, and 4 items for the Dampness Bi) were extracted through the literature review. These items were presented to the 18 Korean medical doctors who specialized in pain medicine to conduct two sessions of the Delphi method. The Korean medical doctors were asked to rate the importance of each item for the corresponding Bi syndromes, using a Likert 7-point scale, and were asked to propose which item should be additionally included to increase determinant power to each Bi syndrome. We determined the 4 points of the importance as a cut-off point of each item. Results: Through two sessions of the Delphi method, two items were deleted because their mean values of the importance were below 4 point. Korean medical doctors proposed to add three items for the Bi Jeung. However, the mean values of only two among the three items were over 4 points, so finally 12 items (3 items for the Wind Bi, 5 items for the Cold Bi, and 4 items for the Damp Bi) were determined for the Bi Jeung questionnaire. Conclusions: It is concluded that a 12 item-Bi Jeung questionnaire comprising the three subcategories of the Bi Jeung (Wind, Cold, and Dampness Bis) possesses contents validity through literature review and Delphi methods.

• Journal of Sasang Constitutional Medicine
• /
• v.25 no.4
• /
• pp.320-329
• /
• 2013

Objectives We carried out this study to know that there is any differences on the health condition of the middle aged women between Sasang coustitution. We used Diagnosis System of Oriental Medicine(DSOM) for diagnosis and determining pattern identification. Methods This research was approved by the Dongeui University Oriental Hospital Institutional Review Board (certificate no. 2011-06). From March 2012 to October 2012, we examined Kupperman's index, the MENQOL, DSOM, and Sasang Constitution of 291 women from the general population, with ages ranging from 40 to 60 years. And we compared the results statistically by the chi-square test and F-test. Results and Conclusions We excluded 4 Taeyangin to analyze because they were few, and analyzed 287 subjects which were 53 Soyangin, 131 Taeeumin, and 103 Soeumin. 1. The pathogenic factors that showed significant differences were deficiency of qi, insufficiency of Yin, heat on the frequency of the output and deficiency of qi, heat, phlegm on the mean of pathogenic factor score. Deficiency of qi was higher in Soeumin, insufficiency of Yin and heat were higher in Taeeumin, and phlegm was higher in Taeeumin and Soeumin. Overall, Soyangin tended to be lower than others on both the frequency of the output and the mean of pathogenic factor score. 2. The middle aged women with ages ranging from 40 to 60 years tended to be dryness, kidney, damp and became to be blood-deficiency, stagnation of qi, heart easily. Soyangin was more health than others, Taeeumin tended to be heat, phlegm, insufficiency of Yang, and Soeumin tended to be deficiency of qi.

• Journal of Haehwa Medicine
• /
• v.15 no.1
• /
• pp.59-69
• /
• 2006

Objectives & Methods : I investigated 45 literature of Oriental and Western medicine about the treatment of pain in shoulder and arm. Result and Conclusion : 1. The etiological causes of Pain in Shoulder and Arm based on literatures of Oriental medicine are attack of wind-heat on the lung, wind cold, damp-heat struggle between the vital energy and pathogenic factor and six pathogenic factors. And all these causes are the conception of blockage syndrome, Qi and blood stagnating in meridian system. 2. The treatment of Pain in Shoulder and Arm based on Oriental medicine is mainly composed of both medical therapy for Bi syndrome due to pathogenic wind, deficiency of both Qi and blood, consumption of the liver and the spleen, and also acupuncture and moxibustion treatment by selection for acupoint. And those treatments are for treating etiology. And also there are treatments using the meridian system and Twelve Muscle Region and Ashihyeol for the purpose of treating the symptoms. 3. The etiological causes of Pain in Shoulder and Arm based on literatures of Western medicine are degenerative cut of tendon and nerve symptoms caused by tendonitis, bursitis, calcification, ruptured cervical disc and thoracic outlet syndrome. 4. The treatment of Pain in Shoulder and Arm based on Western medicine is for alleviation of pain, such as giving an anodyne, steroid products, local anesthetic injection and stretching and strengthening the muscles.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.30 no.2
• /
• pp.37-48
• /
• 2017

Objectives: Artemisiae Annuae Herba is the dried aerial part of Artemisia annua L. (AAL). In Oriental medicine, Artemisiae Annuae Herba (AAH) is traditionally used to treat fever. AAH clears summerheat or damp-Heat, clears deficiency fevers, cools the blood and stops bleeding, stops malarial disorders and relieves heat, clears liver heat and brightens the eyes. Recently, there were many studies about effects of AAH on anti-oxidative, anti-inflammatory, anti-cancer, hair growth and plasma lipid composition. So, we expected AAH has an availability that can effect on skin whitening and elasticity. Methods: The present study was designed to investigate the effects of AAH on skin whitening and elasticity in SK-MEL-2 cells. In this experiment, the effects of AAH on proliferation rates, melanin synthesis, tyrosinase activities and production levels of tyrosinase, MMP-1 and MMP-9 in vitro were examined. Results: AAH did not affect viability of SK-MEL-2 cells and inhibited melanin synthesis induced by ${\alpha}$-Melanocyte-stimulating hormone (${\alpha}$-MSH) significantly. In addition, AAH also inhibited tyrosinase activity and lowered tyrosinase level in SK-MEL-2 cells. Finally, AAH inhibited productions of Matrix metalloproteinase-1 (MMP-1) and Matrix metalloproteinase-9 (MMP-9). Conclusions: These data suggest that AAH can be used to treat patients with skin diseases such as freckled face and also used as skin whitening agent.

• Smart Structures and Systems
• /
• v.20 no.3
• /
• pp.273-283
• /
• 2017

This paper presents and compares three feedback control strategies for active control of noise inside a 3-D vibro-acoustic cavity. These are a) control strategy based on direct output feedback (DOFB) b) control strategy based on linear quadratic regulator (LQR) to reduce structural vibrations and c) LQR control strategy with a weighting scheme based on structural-acoustic coupling coefficients. The first two strategies are indirect control strategies in which noise reduction is achieved through active vibration control (AVC), termed as AVC-DOFB and AVC-LQR respectively. The third direct strategy is based on active structural-acoustic control (ASAC). This strategy is an LQR based optimal control strategy in which the coupling between the various structural and the acoustic modes is used to design the controller. The strategy is termed as ASAC-LQR. A numerical model of a 3-D rectangular box cavity with a flexible plate (glued with piezoelectric patches) and with other five surfaces treated rigid is developed using finite element (FE) method. A single pair of collocated piezoelectric patches is used for sensing the vibrations and applying control forces on the structure. A comparison of frequency response function (FRF) of structural nodal acceleration, acoustic nodal pressure, and piezoelectric actuation voltage is carried out. It is found that the AVC-DOFB control strategy gives equal importance to all the modes. The AVC-LQR control strategy tries to consume the control effort to damp all the structural modes. It is seen that the ASAC-LQR control strategy utilizes the control effort more intelligently by adding higher damping to those structural modes that matter more for reducing the interior noise.

• Journal of Sensor Science and Technology
• /
• v.26 no.1
• /
• pp.39-43
• /
• 2017

Development of vision system as a nondestructive evaluation system can be very useful in screening the defective mechanical parts before they are assembled into the final product. Since the tens of thousands of the mechanical parts are used in an automobile carefully inspecting the quality of the mechanical parts is very important to maximize the performance of the automobile. To sort out the defective mechanical parts before they are assembled, auto parts fabrication companies employ various inspection systems. Nondestructive evaluation systems are getting rapidly popular among various inspection systems. In this study, we have developed a vision system to inspect the inside of the brake caliper, a part that is used to compose a brake which is the most important to the safety of the drivers and the passengers. In a brake caliper, a piston is pushed against the brake disk by oil pressure, causing a friction to damp the rotation of the wheel. Inside the caliper, a groove is positioned to adopt an oil seal to prevent the oil leaks. Inspecting the groove with our vision system, we could examine the existence of the contaminants which are normally the residual tiny pieces from the machining process. We used a high resolution GigE camera, 360 degree lens to look in the inside view of the caliper at once, and a special illumination system in this vision system. We used the edge detection technique to successfully detect the contaminants which were in the form of small metal chips. Labview graphical program was used to process the digital data from the camera and to display the vision and the statistics of the contaminants. We were very successful in detecting the contaminants from the various size calipers. We think we are ready to employ this vision system to the caliper production factories.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.17 no.5
• /
• pp.1237-1245
• /
• 1993

In this study, a model of a flat plate solar collector using a heat pipe was manufactured and tested to investigate such operational characteristics of the present system of solar collector as start-up process, temperature distribution on the absorber plate and operation of the heat pipe. Moreover, collector efficiency was measured for 20-30 minutes of operation at various conditions of weather and the result was compared with that tested by Hill et. a. for a flat plate solar collector using direct circulation of coolant. Some results obtained in this study could be summarized as follows. (1) The required time for the initial start-up process was about 5-6 minutes, but the heat pipe began to operate as soon as the absorber plate was exposed to solar radiation. (2) On the absorber plate, the temperature distributions in axial direction maintained nearly constant, while temperature distributions in transversal direction showed smooth decrease with $3-5^{\cird}C$ along with solar radiation. (3) Thermal inertia of the collector system had a favorable effect to damp the turbulent variation of solar radiation. (4) The collector efficiency of the present system showed nearly the same tendency but a decrease of about 10% compared with that using direct circulation of coolant.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.22 no.4
• /
• pp.939-952
• /
• 1998

Rubber dampers are widely used to damp out vibrations generated in many mechanical elements because of the excellent damping characteristics of rubber. The damping characteristics of rubber is much dependent on temperature and frequency, which, in some cases, limit the effectiveness of rubber dampers. In this study, in order to increase the damping properties and axial and cross stiffnesses of rubber vibration dampers which are used in recording and regenerating devices, solid cores were inserted with interference tolerance in the rubber dampers. The damping characteristics of the rubber dampers with cores were investigated by experimentally and numerically using finite element method with respect to the interference tolerance, the core roughness, the materials of the core and the environmental temperature. From the experimental and theoretical investigations, it was found that the core in the rubber increased both the damping and stiffness of the damper. Also, it was found that the damping and stiffness of the rubber damper were much dependent on the temperature and frequency. Using the results of the experimental and theoretical investigations, the optimum design method for the cored rubber damper for recording and regenerating devices was developed.