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Chemotaxonomic Significance of Oregonin in Alnus japonica Native to Baekdudaegan Mountain Range in Korea

  • Hyeondu Jang (Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University) ;
  • Sunmin Park (Dr. Oregonin Inc.) ;
  • Seong Gyeom Kim (Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University) ;
  • Seung Bin Bae (Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University) ;
  • Hee Jeong Min (Gangwon State Forest Science Institute) ;
  • Chan Ok Lee (Gangwon State Forest Science Institute) ;
  • Hee Kyu Kim (Gangwon State Forest Science Institute) ;
  • Jin-Kyu Kim (Gyeonggido Business and Science Accelerator) ;
  • Sun Eun Choi (Department of Forest Biomaterials Engineering, College of Forest and Environmental Sciences, Kangwon National University)
  • Received : 2024.01.19
  • Accepted : 2024.02.12
  • Published : 2024.03.31

Abstract

Alnus japonica is indigenous to korea and usually grows in wet lowlands and damp regions in the mountains. Oregonin, is known as a representative compound of the diarylheptanoid mainly found in Alnus species and has been reported to have anti-inflammatory and antioxidant effects. In this experiment, we conducted a study on the presence of orogonin in the native Alnus japonica from the Baekdudaegan mountain range in Korea. We collected a total of 30 samples from Chuncheon, Yangyang, and Jeongseon and conducted experiments. In the HPLC analysis, we confirmed that oregonin was detected in all samples. After the quantitative analysis, samples with the highest content from each region were selected and LC-MS/MS experiments were performed. As a result, the same molecular weight as oregonin, 477.2 m/z, was confirmed in all samples.

Keywords

Acknowledgement

This study was carried out with the support of 'R&D Program for Forest Science Technology (Project No. 2023469A00-2425-EE01, 2019151D10-2323-0301)' provided by Korea Forest Service(Korea Forestry Promotion Institute), and this research was supported by 2023 Regional Industry-linked University Open-Lab Development Support Program through the Commercializations Promotion Agency for R&D Outcomes (COMPA) funded by Ministry of Science and ICT (Research No. 1711202074), and also partially supported by the Starting growth Technological R&D Program (TIPS Program, [RS-2023-00222349]) funded by the Ministry of SMEs and Startups (MSS, Korea) in 2023.

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