• Title/Summary/Keyword: D8/17

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A PRELIMINARY STUDY OF B LYMPHOCYTE ANTIGEN D8/17 IN TOURETTE SYNDROME CHILDREN WHO SUGGESTED PANDAS (PANDAS가 의심되는 뚜렛장애 아동에서의 B 임파항원 D8/17에 관한 예비연구)

  • Joung Yoo-Sook;Lee Young-Sik
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.17 no.1
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    • pp.27-31
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    • 2006
  • Objectives : We examined whether D8/17 expression in Tourette syndrome children who suggested PANDAS were higher than comparison group, and there was my clinical difference by D8/l7 expression. Methods : Nine Tourette's syndrome children suggested PANDAS and two ADHD children without tic disorder were evaluated far percentage of D8/17 expression-positive B cells by immunofluorescence flow cytometric assay and anti-streptolysin O titer. Results : The frequency of D8/17 positive B lymphocyte rate was significantly higher in Tourette's syndrome than ADHD, whose average rate were 77.9 and 24.8, respectively. Among 9 TD patients,4 patients showed above 90% D8/l7 expression. There was high concordance expression rate between mother (98.4%) and daughter (99.0%) The significant relation between percentage of D8/17 expression and tic severity were not detected. The significant relation between percentage of D8/17 expression and anti-streptolysin O titer were not detected, however in 66.7% TD patients showed above 100IU/ml. Conclusion : We concluded that subgroup of TD children are streptococcal infected tic disorder, so called PANDAS.

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D8/17 Expression on B Lymphocytes of Children and Adolescents with Tic Disorder (소아청소년 틱장애 환자의 B림프구에서 D8/17의 발현)

  • Oh, Young-Gun;Park, Tae-Won;Jung, Yong Woo;Chung, Sang-Keun;Chung, Young-Chul;Yang, Jong-Chul
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.24 no.3
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    • pp.151-156
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    • 2013
  • Objectives : It has been reported that higher percentage of B cells react with monoclonal D8/17 antibody in patients with rheumatic fever, childhood onset obsessive-compulsive disorder, Tourette's disorder, or prepubertal anorexia nervosa. The purpose of this study is to replicate the previous studies in a Korean young population with tic disorder and to identify any relationship between D8/17 and clinical symptoms. Methods : The binding of D8/17 to B cells was determined in patients with tic disorder (N=21) and healthy controls (N=9) by Fluorescence-Activated Cell Sorter analysis. Results : In the sample examined by this study, the average percentage of B cells expressing D8/17 in tic disorder was 2.05%; healthy controls was 3.15%. No statistically significant differences were found in the mean percentages of D8/17 between the two groups. Conclusion : The expression of D8/17 in B cells was very low in this study. No subjects with tic disorder or healthy controls was above 12% in D8/17 positive proportion. Further studies, including higher number of patients and control group members, should be performed.

Extractives from the Sapwood of Betula maximowicziana (큰잎자작(Betula maximowicziana) 변재의 추출성분)

  • Lee, Hak-Ju;Kato, Atsushi
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.2
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    • pp.45-51
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    • 2003
  • One flavonoid, lignan glycosides and two diarylheptanoids were isolated from the sapwood of Betula maximowicziana. The structures were determined as : catechin 7-O-𝛽-D-xylopyranoside, lyoniresinol 9'-O-𝛽-D-glucopyranoside, 11-oxo-3, 8, 12, 17-tetrahydroxy-9-ene[7, 0]-metacyclophane and 11-oxo-3, 8, 9, 10, 12, 17-hexahydroxy[7, 0]-metacyclophane, respectively, on the basis of spectrosopic data and chemical correlations.

The Design of Image Rejection Mixer (이미지 제거 혼합기의 설계)

  • Kang, Eun Kyun;Jeon, Hyung Jun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.5
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    • pp.123-127
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    • 2017
  • This paper fabricated and analyzed the image rejection mixer that uses FET's channel resistance. It can be applied for capacity 64QAM that has 50MHz~90MHz of IF band, 8.17GHz of LO frequency and 8.08~8.12GHz of RF band. When IF input power is -20dBm and LO input power is 10dBm, RF output power is obtained -33.2dBm. In this case, conversion loss is 12.9dB, the suppression of 14.3dB for LO frequency and 10.4dB for image frequency. The result of two tone test shows great IMD characteristics with 51.7dBc.

Wide Bandwidth Circularly Polarized Aperture Coupled Microstrip Antenna using Cross-slot (십자 슬롯을 이용한 광대역 원형편파 적층 개구결합 마이크로스트립 안테나)

  • 양태식;이범선
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.11 no.5
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    • pp.748-754
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    • 2000
  • A novel single feed wide band CP stacked microstrip antenna using crossed slots has been designed, fabricated and measured. For the single rediating element the designed 10dB return loss bandwidth is 34.5%99.45~13.54 GHz), 3dB axial ratio bandwidth is 18.7%(11.17~13.39GHz), and 6 dB gain bandwidth is 29%(10.21~13.64GHz). For the 2$\times$2 array designed using a sequential rotation method, the 10dB return loss bandwidth is 35.9%(9.69~13.94GHz), 3dB axial ratio bandwidth is 34.6GHz (9.93~14.03GHz), and 6dB gain bandwidth is 27.4%(10.35~13.6GHz). For the fabricated 8$\times$8 array antenna, the 10dB return loss bandwidth is 27.3%(10.17~13.41GHz), 3dB axial ratio bandwidth is 27.9GHz(10.1~13.4GHz), and the radiation pattern is good agreement with theory. This antenna can be used for broadband applications for communications or broadcasting in Ku band.

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Design and Fabrication of a Weathercock-Shaped Double Bandwidth Microstrip Patch Antenna that Combines U-slot and Short-pin for WLAN Systems Systems (WLAN System을 위한 U-slot 및 Short-pin 결합한 바람개비 모양의 이중대역(5.2/5.8GHz) 마이크로스트립 패치 안테나 설계 및 제작)

  • Kim, Soon-Seob;Choi, Young-June;Joo, Young-Dal;Jung, Yoong-Joo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.5
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    • pp.337-343
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    • 2013
  • In this paper, IEEE 802.11 based WLAN(5.2/5.8GHz) wideband Weathercock-shaped microstrip patch antenna was designed and manufactured. The antenna has a size of $17.4{\times}17.4mm^2$ and utilized FR-4 board. The size was minimized for mobility, and Weathercock-shaped U-slot and short-pin was inserted to satisfy adequate bandwidth and double bandwidth resonance characteristics. In addition, the antenna incorporated single both-sided patch, and simulation design optimized the Weathercock-shaped, position of the U-slot and the short-pin, and the length of the patch for the measurement. The manufactured antenna achieved a bandwidth of 695MHz from 5.2~5.8GHz zone(Return loss<-10dB). Achieved a beam width of $81.13^{\circ}$ and $85.43^{\circ}$ for 3-dB beam width of H plane and E p;ane radiation pattern, there was 3.17~4.85dBi gain.

Prevalence of Dirofillaria immitis in Raccoon Dogs (Nyctereutes procyonoides) in Korea (한국 너구리(Nyctereutes procyonoides)의 심장사상충감염에 대한 유병률)

  • Nam, Hyo-Seung;Kim, Jong-Taek;Yang, Dong-Keun;Hyun, Changbaig
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.453-455
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    • 2013
  • Heartworm infection is a fatal disease causing heart failure and pulmonary diseases in dogs. This heartworm infection can also occur in wild carnivores including Raccoon dogs. Recent study found that relatively high prevalence rate in wild Raccoon dog population. Therefore, this study was designed to evaluate the prevalence rate of D. immitis in free-roaming Raccoon dogs and the recovery rate of microfilariae in infected Raccoon dogs in Korea. Overall prevalence rate of D. immitis in Korean Raccoon dogs was 17.8%. Prevalence rate in male Raccoon dogs was 21.8%, while that in female Raccoon dogs was 12.8%. Microfilariae were not detected in 17 Raccoon dogs having positive in heartworm antigen test. Our study result suggested that the prevalence rate of D. immitis in Korea is twice higher than that of Japan. In addition, microfilaremia is rare in Raccoon dogs as commonly noticed in cats.

Synthetic Studies on Carbapenam Skeletons

  • 구양모;서민효;이윤영
    • Bulletin of the Korean Chemical Society
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    • v.17 no.10
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    • pp.909-918
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    • 1996
  • Syntheses of carbapenam skeletons were achieved from 1,3-propanediol through 1,3-dipolar cycloaddition. 3-(Tetrahydropyran-2-yloxy)-(10) and 3-(t-butyldimethylsilyloxy) propanal (13) were obtained from 1,3-propanediol. 3-Hydroxypropanals (10, 13, 14) were reacted with N-hydroxyglycine esters to give C-(2-hydroxyethyl)-N-alkoxycarbonylmethylnitrones (15a-15d). 1,3-Dipolar cycloaddition of the nitrones with methyl acrylate or ethyl crotonate gave 3-(2-hydroxyethyl)isoxazolidines (16a-16b, 17a-17b, 18, 19a-19b). 3-(2-Hydroxyethyl)isoxazolidines (17a, 17c, 19a, 19b) were converted to 3-(2-iodoethyl)isoxazolidines (21a-21d) or 3-phenylthiocarbonylmethylisoxazolidines (25a-25d) which were cyclized to give 2-oxa-1-azabicyclo[3.3.0]octanedicarboxylates (22a-22d, 26a-26d). 2-Oxa-1-azabicyclo[3.3.0]octane-4,8-dicarboxylates (22c-22d, 26c-26d) were transformed to 6-(l-hydroxyethyl)carbapenam-3-carboxylates (30a-30b, 31a-31b).

Design of an Ultra Wide Band Band-pass Filter with Open-Stubs (초광대역 개방형 스터브 대역통과 여파기의 설계)

  • Yoon, Ki-Cheol;Kang, Chul-Ho;Hong, Tae-Ui;Lee, Jong-Chul
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.12 no.6
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    • pp.37-43
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    • 2013
  • In this paper, an UWB (Ultra Wide Band) band-pass filter with open stubs using SIR (Stepped Impedance Resonator) structure is presented. The proposed band pass filter (BPF) has SIR structure instead of open stubs for UWB application with low insertion loss. The bandwidth of the proposed BPF is 103 % at the center frequency of 5.8GHz and the insertion and return losses are 0.17dB and 13.1dB, respectively. Also, the entire size of the proposed band-pass filter is $21.6{\times}17.8mm^2$.

Analysis of Power Amplifier Phase Distortion Characteristics for IEEE 802.11a OFDM Wireless LAM Using Phase Predistortion (사전위상 왜곡을 이용한 IEEE 802.11a OFDM 무선랜 전력증폭기 위상왜곡 특성분석)

  • Oh Chung Gyun;Choi Jae Hong;Koo Kyung Heon
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.42 no.2 s.332
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    • pp.75-80
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    • 2005
  • In this paper, 2-stage power amplifier has been designed for 5.8GHz wireless LAN application. The power amplifier PldB output power has 21.6dBm at 5.8GHz frequency. Also the power amplifier shows 17.6dB gain and -17.8dB input return loss at 5.725GHz to 5.825GHz. The OFDM modulation and transmission block have been modeled in order to analyse the relationship between the power amplifier distortion and output ACPR for the IEEE 802.11a wireless LAN. The nonlinear characteristic of the power amplifier has been modeled as AM-to-AM and AM-to-PM using the behavioral model, and the output spectrum is analysed with the phase distortion variation. Also, amplifier back-off value from PldB to satisfy the required IEEE 802.11a standard spectrum mask has been simulated with phase distortion, and the simulation data have been compared to the measurement result collected by using the pre-distortion technique.