• Proceedings of the Korean Society of Sericultural Science Conference
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• 한국잠사학회 2003년도 제46회 춘계 학술연구 발표회
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• pp.43-43
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• 2003

잠란의 휴면 개시, 유지 및 각성 등에 따른 단백질의 변화를 알아보기 위해 2D-전기영동에 의한 peptides 분석을 하였다. 잠품종은 백옥잠을 사용하였으며, 단백질 분석은 산란 후 5일 경과란(휴면란), 산란 후 20시간에 침산하여 1일 및 2일 경과란, 및 산란 후 2일 경과 후 냉장(5$^{\circ}C$)처리하여 1일, 3일, 5일된 잠란을 각각 대상으로 하였다. 2D-전기영동은 1차로 pH3-10 range에서 isoelectric focusing 하고 2차로 SDS-PAGE한 후 silve stainin으로 peptides를 검출하였다. (중략)

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5477-5482
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• 2015

Background: This study aimed to investigate the incidence and risk factors for a prethrombotic state in patients with malignant tumors. Materials and Methods: Plasma d-dimer (D-D) in patients with malignant tumors was measured. Abnormal rates of D-D and possible risk factors like gender, age, type of tumor, and staging of tumor were analyzed. Results: Of 1,453 patients, 629 demonstrated plasma D-D abnormality (43.3%). The D-D abnormal rate of male patients (n=851, 43.5%) was not statistically significantly different from that for female patients (n=602, 43.0%) (p>0.05). D-D abnormal rate increased with age and was statistically significant among different age groups (p<0.05). Regarding staging of tumor, D-D abnormal rate in patients with phase I was 2.0%, 6.2% in phase II, 47.6% in phase III and 83.1% in phase IV, with statistically significant differences between phase III and II, as well as phase III and IV (p<0.01). Conclusions: A prethrombotic state was closely related to malignancy of tumors. The risk factors for a prethrombotic state include age and tumor stage.

• BMB Reports
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• 제32권4호
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• pp.363-369
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• 1999

The orf8(chlD) gene cloned from Streptomyces antibioticus T$\"{u}$99 was overexpressed using an E. coli system to confirm its biological function. Induction of the E. coli strain transformed with recombinant plasmid pRFJ 1031 containing orf8 resulted in the production of a 43,000 dalton protein. Glucose-1-phosphate thymidylyltransferase activity of the cell extract obtained from the transformed strain was 4-5 times higher than that of the control strain. The expressed protein was purified 18-fold from E. coli cell lysate using three chromatographic steps with a 17% overall recovery to near homogeneity. The N-terminal amino acid sequence of the purified protein agrees with the nucleotide sequence predicted from the orf8 gene. The SDS-PAGE estimated subunit mass of 43,000 dalton agrees well with that calculated from the amino acid composition deduced from the nucleotide sequence of the orf8 gene (43,000 Da). Also, the native enzyme has a monomeric structure with a molecular mass of 43,000 dalton. The purified protein showed glucose-1-phosphate thymidylyltransferase activity catalyzing a reversible bimolecular group transfer reaction, and was highly specific for dTTP and ${\alpha}$-D-glucose 1-phosphate as substrates in the forward reaction, and for dTDP-D-glucose and pyrophosphate in the reverse reaction.

• Journal of Korean Institute of Industrial Engineers
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• 제43권2호
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• pp.90-99
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• 2017

As the importance of R&D has increased, there have been various efforts to apply the quality management principles and tools to R&D activities in order to manage them effectively. The R&D sector differs from other value chains, so it may be difficult to apply quality management without proper considerations of R&D characteristics. This study describes the characteristics of R&D as high uncertainty and risk, diversity of R&D types, project-based activities, importance of strategic goals and business models, and importance of intangible assets. Three well accepted R&D quality management models are reviewed and implications for quality management and R&D characteristics are summarized. Based on these findings, the management targets of R&D quality management are classified into management level (organization, project) and management focus (process, output), and the contexts of R&D quality management are classified into R&D type (research, development) and market/customer requirement clarity (fluid, specific), and appropriate R&D quality management activities in each situations have been suggested.

• Journal of Korean Society of Industrial and Systems Engineering
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• 제43권1호
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• pp.79-86
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• 2020

The effects of R&D investment on innovation such as patents and intangible assets, and the effect on the corporate performance such as revenue and profit growth, were analyzed using path analysis. In particular, this study compared and analyzed the performances of non-cooperative R&D and cooperative R&D. The results of this study are summarized as follows. First, R&D investment has a significant impact on innovation performance. This supports the existing research results. Second, patents have a significant impact on intangible asset growth. Third, in the case of corporate groups carrying out cooperative R&D, intangible asset growth forms a significant causal relationship with revenue growth. Fourth, in case of cooperative R&D, intangible asset growth has a significant mediating effect between patent and revenue growth. Like the existing research, the results of this research support the innovation performance of R&D investment. It also supports the existing argument that the results of cooperative R&D are more favorable to increase corporate value. However, unlike the existing research, we found a path leading to increased revenue through patents and intangible assets, and confirmed that such a path is likely to be achieved through cooperative R & D rather than internal R&D.

• Korean Journal of Optics and Photonics
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• 제16권2호
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• pp.143-145
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• 2005

We demonstrated 5.12-Tb/s($l28 ch \times 43 Gb/s$) WDM transmission over 200 km of medium dispersion fiber. The spectral efficiency was 0.8-(bits/s)/Hz. After transmission, the average Q-factor was measured to be 15.2 dB.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• 제10권5호
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• pp.757-765
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• 1999

In this paper, L-Type aperture coupled circular polarization patch antenna for mobile communication(IMT-2000, 1.9375 GHz), which is capable of being mounted in mobile unit, was designed and fabricated. This antenna is expanded to the $2\times2$ circular polarization array antenna for satellite mobile communications which are using the L-band frequency. The results are as followings : Returnloss 18.56 dB, beamwidth $60^{\circ}$, gain 7 dBd, axial ratio 0.9 dB in the case of single element and returnloss 28.43 dB, beamwidth $38^{\circ}$, gain 9.8dBd, axial ratio 1.5 dB in the case of $2\times2$ array, respectively.

• Journal of Korean Institute of Industrial Engineers
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• 제43권2호
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• pp.120-126
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• 2017

This paper has proposed the development direction and R&D analysis approach that the diversity of defense R&D process and product should be mainly under consideration. It has shown that there is a fair possibility of the various quality assess to meet the R&D requirements in defense-based. Thus, the analysis on multiple quality elements is carried out with defense R&D characteristics. Especially, a quality management master planning based on the quality model of establishing defense R&D policy has proposed, identifying relevant quality characteristics on the R&D of weapon system and the R&D of core technology. That is, this paper is not only interested in determining an appropriate model for improving the quality of a R&D weapon system but also argued efforts in order to reap the best possible outcome and process on both the R&D of weapon system and quality of the R&D of core technology including present R&D activities.

• Proceedings of the Korean Nutrition Society Conference
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• 한국영양학회 2004년도 추계학술대회
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• pp.38-43
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• 2004

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.693-695
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• 2015

The design and implementation of a broadband and linear HPA for TVWS are presented in this paper. The spectrum mask and transmitted power of HPAs for TVWS must be controlled and meet the regulations to minimize interference effects on the present broadcasting systems. The implemented HPA has the operating frequency of 470 ~ 698MHz with the maximum 48.63dB and minimum 43.45dB gain, input reflection coefficient of below -21.32dB, output reflection coefficient of below -4.29dB and the linearity of -45.24dBc at 28.79dBm output power.