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http://dx.doi.org/10.7314/APJCP.2015.16.13.5477

Analysis of Prethrombotic States in Patients with Malignant Tumors  

Cui, Lin (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Sun, You-Hong (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Chen, Jue (Meidicall college of Yangzhou University)
Wang, Lu (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Liu, Jian-Jun (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Zhou, Xiang-Rong (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Ding, Jie (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Liu, Xing-Xiang (Department of Oncology, Taizhou Second People’s Hospital, the Affiliated Hospital of Yangzhou University)
Huang, Xin-En (Department of Chemotherapy, Affiliated Jiangsu Cancer Hospital of Nanjing Medical University & Jiangsu Institute of Cancer Research)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.16, no.13, 2015 , pp. 5477-5482 More about this Journal
Abstract
Background: This study aimed to investigate the incidence and risk factors for a prethrombotic state in patients with malignant tumors. Materials and Methods: Plasma d-dimer (D-D) in patients with malignant tumors was measured. Abnormal rates of D-D and possible risk factors like gender, age, type of tumor, and staging of tumor were analyzed. Results: Of 1,453 patients, 629 demonstrated plasma D-D abnormality (43.3%). The D-D abnormal rate of male patients (n=851, 43.5%) was not statistically significantly different from that for female patients (n=602, 43.0%) (p>0.05). D-D abnormal rate increased with age and was statistically significant among different age groups (p<0.05). Regarding staging of tumor, D-D abnormal rate in patients with phase I was 2.0%, 6.2% in phase II, 47.6% in phase III and 83.1% in phase IV, with statistically significant differences between phase III and II, as well as phase III and IV (p<0.01). Conclusions: A prethrombotic state was closely related to malignancy of tumors. The risk factors for a prethrombotic state include age and tumor stage.
Keywords
Prethrombotic state; malignant tumor; riask factors;
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