• Title/Summary/Keyword: D.P.T

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MODULAR MULTIPLICATIVE INVERSES OF FIBONACCI NUMBERS

  • Song, Hyun-Jong
    • East Asian mathematical journal
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    • v.35 no.3
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    • pp.285-288
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    • 2019
  • Let $F_n$, $n{\in}{\mathbb{N}}$ be the n - th Fibonacci number, and let (p, q) be one of ordered pairs ($F_{n+2}$, $F_n$) or ($F_{n+1}$, $F_n$). Then we show that the multiplicative inverse of q mod p as well as that of p mod q are again Fibonacci numbers. For proof of our claim we make use of well-known Cassini, Catlan and dOcagne identities. As an application, we determine the number $N_{p,q}$ of nonzero term of a polynomial ${\Delta}_{p,q}(t)=\frac{(t^{pq}-1)(t-1)}{(t^p-1)(t^q-1)}$ through the Carlitz's formula.

Identification and Functional Analysis of RelA/SpoT Homolog (RSH) Genes in Deinococcus radiodurans

  • Wang, Jinhui;Tian, Ye;Zhou, Zhengfu;Zhang, Liwen;Zhang, Wei;Lin, Min;Chen, Ming
    • Journal of Microbiology and Biotechnology
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    • v.26 no.12
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    • pp.2106-2115
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    • 2016
  • To identify the global effects of (p)ppGpp in the gram-positive bacterium Deinococcus radiodurans, which exhibits remarkable resistance to radiation and other stresses, RelA/SpoT homolog (RSHs) mutants were constructed by direct deletion mutagenesis. The results showed that RelA has both synthesis and hydrolysis domains of (p)ppGpp, whereas RelQ only synthesizes (p)ppGpp in D. radiodurans. The growth assay for mutants and complementation analysis revealed that deletion of relA and relQ sensitized the cells to $H_2O_2$, heat shock, and amino acid limitation. Comparative proteomic analysis revealed that the bifunctional RelA is involved in DNA repair, molecular chaperone functions, transcription, the tricarboxylic acid cycle, and metabolism, suggesting that relA maintains the cellular (p)ppGpp levels and plays a crucial role in oxidative resistance in D. radiodurans. The D. radiodurans relA and relQ genes are responsible for (p)ppGpp synthesis/hydrolysis and (p)ppGpp hydrolysis, respectively. (p)ppGpp integrates a general stress response with a targeted re-programming of gene regulation to allow bacteria to respond appropriately towards heat shock, oxidative stress, and starvation. This is the first identification of RelA and RelQ involvement in response to oxidative, heat shock, and starvation stresses in D. radiodurans, which further elucidates the remarkable resistance of this bacterium to stresses.

Effect of Different Commercial Oligosaccharides on the Fermentation Properties in Kefir during Fermentation

  • Oh, Nam Su;Lee, Hyun Ah;Myung, Jae Hee;Lee, Ji Young;Joung, Jae Yeon;Shin, Yong Kook;Baick, Seung Chun
    • Food Science of Animal Resources
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    • v.33 no.3
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    • pp.325-330
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    • 2013
  • Kefir is traditional fermented milk produced by various lactic acid bacteria (LAB) and yeast, which produce lactic acid, ethanol, carbon dioxide, and other flavor compounds. The purpose of this study was to evaluate the effects of different commercial oligosaccharides, such as maltotriose, fructooligosaccharide (FOS), galactooligosaccharide (GOS), and isomaltooligosaccharide (IMO), on the fermentation properties of kefir. First, we determined the acidification kinetic parameters, such as $V_{max}$, $t_{max}$(h), $t_{pH5.0}$(h), and $t_f$(h) of fermented milk supplemented with 4% (w/w) of different oligosaccharides. The probiotic survival and chemical composition (pH, organic acids profile, and ethanol content) of kefir during fermentation were also measured. Compared to control fermentation, all oligosaccharides increased acidification rate and reduced the time to complete fermentation (pH 4.7). The addition of FOS, in particular, resulted in the lowest $t_f$(h) and the highest populations of LAB and yeast during fermentation. All oligosaccharides increased ethanol production during fermentation. Further, significant differences were observed in the formation rates of six organic acids during fermentation. This study provided comparative data on the properties of commercial oligosaccharides for kefir manufacturing. Consequently, FOS especially had the potential for adequate and effective oligosaccharides in commercial kefir for the improvement of cost- and time-effectiveness.

Effects of Supplementing Coated Vitamin C+E with Cottonseed on Meat Composition, Meat Color and Carcass Grade in Hanwoo Steers Fed Brewers Grain and Cracked Corn-Based Fermented Feedstuff (맥주박과 옥수수 위주의 발효사료에 대한 Coated Vitamin C+E 및 면실의 첨가가 거세한우의 육조성분, 육색 및 도체등급에 미치는 영향)

  • 박병기;성대경;김창혁;권응기;오상집;신종서
    • Journal of Animal Science and Technology
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    • v.48 no.2
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    • pp.227-236
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    • 2006
  • Twenty four Hanwoo steers(average body weight=550.4±42.8kg) were used in the experiment to determine the effects of supplementing coated vitamin C+E with cottonseed on meat quality, meat color and carcass grade in Hanwoo steers fed brewers grain and cracked corn-based fermented feedstuff. Steers were randomly assigned to feeding groups of fermented feedstuff without any supplements(T1) and fermented feedstuff supplemented with coated vitamin C+E and cottonseed(T2). Ether extract content of longissimus dorsi was higher in T2 than in T1(p<0.05). Yellowness and hue-angle among surface colors of longissimus dorsi was lower(p<0.05) in T2 than in T1 but lightness was higher(p<0.05) in T2 than in T1. Ratio of yield grade ‘A’ was higher from T2 group than from T1 group. Marbling score was higher in T2 than in T1(p<0.05). Present results indicate that supplementation of coated vitamin C+E and cottonseed to brewers grain and cracked corn-based fermented feedstuff has positive effects on ether extract content, color, marbling score of longissimus dorsi in Hanwoo steers.

The Effects of Hand Moxibustion Therapy on Decreasing Pain and Relieving Coldness of Women with a Hysterectomy (자궁적출술을 경험한 여성의 통증과 냉증완화를 위한 쑥뜸요법 효과의 예비연구)

  • Shin, Kyung Rim;Kwak, Soon Ae;Shin, Su Jin
    • Korean Journal of Adult Nursing
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    • v.13 no.1
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    • pp.159-170
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    • 2001
  • The purpose of this pilot study was to identify the effects of hand moxibustion therapy to decrease pain and relieve coldness of the body in women who had a hysterectomy. The conceptual framework of this study was derived from Ying-Yang, Khi and other corresponding theories. The data were collected from February to May 1997. A Graphic Rating scale was used to measure the degree of pain and Digital Infrared Thermographic Imaging(D.I.T.I) was used to examine the degree of coldness. The subjects were women who resided in Seoul and had a hysterectomy within five years. An experimental group was composed of five women who received moxibustion and a control group was composed of five who did not. The research procedure began with having both the experimental group and control group describe their general characteristics and the degree of pain they perceived. Then, Digital Infrared Thermographic Imaging(D.I.T.I) was conducted. Moxibustion was only given to the experimental group on both hands twice every day for a total of five weeks. Their perception of pain and D.I.T.I were examined weekly. The control group received no therapy. After finishing therapy, the perception of pain and D.I.T.I for both groups were also measured. According to this study, moxibustion therapy resulted in a change of body temperature on the right shoulder joint(p=0.00074), abdomen(p= 0.0047), waist(p=0.0068) and hands(p=0.0317) respectively. Also, the study results showed significant decrease (p=0.0001) in pain over time and significant improvement over body coldness.

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Effect of Nurse's Perception of People with Disabilities, Experience of Contact with Persons with Disabilities, and Human Rights Sensitivity on Attitudes toward Persons with Disabilities (간호사의 장애인에 대한 인식, 장애인 접촉경험, 인권감수성이 장애인에 대한 태도에 미치는 영향)

  • Ahn, Eun-young;Lee, Hye-Kyung
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.2
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    • pp.205-219
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    • 2022
  • This study is a descriptive research study to understand the effects of nurses' perception of the disabled, contact experience with the disabled, and human rights sensitivity on attitudes toward the disabled. The subjects of the study were 181 nurses working at two university hospitals in D City and one university hospital in C Special Self-Governing City. Data were collected from September 2, 2021 to October 6, 2021. The collected data wre analyzed using IBM SPSS 26.0 program, and analyzed with t-test, ANOVA, Pearson's Correlation Coefficients, and Multiple Regression Analysis. Factors affecting the subject's attitude toward people with disabilities were perception of people with disabilities(t=-3.96, p<.001), presence or absence of contact with patients with disabilities(t=3.23, p=.001), and the ability to perceive responsibility among human rights sensitivity(t=2.13, p=.035), whether or not they had completed education for improvement the awareness of the disabilities(t=2.90, p=.004), and whether they were recognized of the Act on the Right to Health and Medical Accessibility for the Disabled(t=2.44, p=.016), which showed 30% of explanatory power(F=9.36, p<.001). Accordingly, it is necessary to develop an educational program that can foster nurses' attitudes toward the disabled, including awareness of the disabled, human rights sensitivity, the Health Rights Act for the Disabled, and the experience of contact with the disabled.

Change of Serum Levels of C-Reactive Protein After Coronary Angioplasty and Its Effects on Clinical Restenosis (협심증 환자에서 관동맥중재술에 따른 C-reactive Protein의 변화 및 임상경과)

  • Park, Jong-Seon;Hong, Gu-Ru;Lee, Chae-Hoon;Shin, Dong-Gu;Kim, Young-Jo;Shim, Bong-Sup
    • Journal of Yeungnam Medical Science
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    • v.18 no.2
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    • pp.215-225
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    • 2001
  • Background: There are many evidences that inflammation is an important determinant of the development of atherosclerosis and one of the systemic markers of inflammation, C-reactive protein(CRP), is associated with extent of coronary artery disease and risk of coronary events. We assessed the time response of CRP response after coronary angioplasty and it's influence on the clinical restenosis in angina patients. Materials and Methods: Patients included 36 angina patients undergoing single vessel angioplasty. Levels of CRP were measured before and 12, 24, 48, and 72 hours after angioplasty. Clinical restenosis was assessed at 6 months after procedure. Results: Baseline CRP level was $0.30{\pm}0.01$ mg/dL in stable and $0.46{\pm}0.28$ mg/dL in unstable angina patients(p<0.05). After angioplasty, CRP level was increased with peak at 24 hour and persisted to 72 hours after angioplasty. At 24 hour after angioplasty, the magnitude of CRP change was $0.32{\pm}0.31$ mg/dL in stable and $0.79{\pm}0.73$ mg/dL in unstable angina patient(p<0.05). The change of CRP level was not associated with troponin-T after angioplasty. In unstable angina patients, clinical restenosis was developed in 8% of patients with low baseline CRP levels and in 50% of those with high baseline CRP levels more than 0.6 mg/dL(p<0.05). Conclusion: In unstable angina patients, inflammatory response is more increased than stable angina patients, and increased inflammatory response effects on the restenosis after coronary angioplasty.

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Quantity and Characteristics of Manure Produced by Holstein Heifer at Different Seasons (홀스타인 육성우의 계절별 분뇨 배설량 및 특성에 관한 연구)

  • Choi, D.Y.;Kwag, J.H.;Park, C.H.;Jeong, K.H.;Kim, T.I.;Kim, J.H.;Yoo, Y.H.;Yang, C.B.;Hong, H.L.
    • Journal of Animal Environmental Science
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    • v.12 no.3
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    • pp.123-132
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    • 2006
  • This study was conducted to determine the volume of Holstein heifers manure excreted and its characteristics. The average dry matter intake of heifers was 6.7 kg/head/day. The intake rate was lowest in spring among four seasons. The average dry matter intake rate during spring, summer, fall, and winter was 4.6, 8.3, 7.1, and 6.8 kg/head/day, respectively. The average water intake of heifers was $19.3{\ell}/head/day$. The wale. consumption was highest value ($21.8{\ell}/head/day$) in summer and lowest values ($18.3{\ell}/head/day$) in spring and winter. Values were found not to be statiscally different for the four seasons. The average manure production of heifers (average live weight was 363.1 kg) was 20.3 kg/head/day and it was 5.6% of live animal weight. The manure production during spring, summer, fall, and winter was 13.7, 23.5, 25.0, and 20.2 kg/head/day, respectively. Production during spring was lower than the other seasons (p<0.05). A higher correlation between live weight and manure production ($R^2=0.7816$) and between live weight and feed intake ($R^2=0.7296$) was observed for heifers. Correlations between manure production and water intake and between manure production and feed intake were found to be relatively low for heifers. The moisture content of feces was 83.5% and that of urine 94.6%. The pH of feces and urine were in the ranges of 7.4 and 7.5, respectively. The $BOD_5$, COD, SS, T-N, T-P concentrations of the heifer feces were 18,048, 50,114, 119,833, 2,519, and $427mg/{\ell}$, respectively. Heifer urine showed lower levels of $BOD_5(5,434mg/{\ell})$, COD$(6,550mg/{\ell})$, SS$(825mg/{\ell})$, T-N$(3,616mg/{\ell})$, and $T-P(28mg/{\ell})$ than feces. The fertilizer nutrient concentrations of heifer feces was 0.25% N, 0.1% $P_2O_5$ and 0.14% $K_2O$. Urine was found to contain 0.36% N, 0.006% of $P_2O_5$ and 0.31% $K_2O$.

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Synthesis and Configuration Analysis of Diastereomers of 5'-O-(2'-Deoxycytidyl)-3'-O-Thymidyl Phosphorothioate

  • Mun, Byeong Jo;Jeong, Hyeon Ju;Kim, Sang Guk;Kim, Nam Hui
    • Bulletin of the Korean Chemical Society
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    • v.17 no.1
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    • pp.24-28
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    • 1996
  • A procedure is described for the synthesis of the title compound via phosphotriester intermediates. The preparation of $R_p$ and $S_p$ diastereomeric dinucleotide of d[Cp(S)T] was performed by the condensation of the protected deoxycytidine, the protected thymidine, 2,5-dichlorophenylphosphorodichloridothioate and 1-hydroxybenzotriazole in THF. Their designation of configuration at phosphorus as $R_p$ and $S_p$ follows from anaylsis of ${31}^P$ NMR spectroscopy and reverse-phase HPLC and the stereospecificity in the hydrolysis catalyzed by Nuclease S1 and snake venom phosphodiesterase. Diastereomerically pure $R_p$ and $S_p$ d[Cp(S)T] were utilized to synthesize oligonucleotides containing the XhoI recognition sequence with a phosphorothioate group at the cleavage site.

The effects of Doula Touch delivery education on self-confidence delivery, knowledge of childbirth, couple satisfaction (듀라터치 분만 교육이 분만 자신감, 분만지식, 부부관계만족도에 미치는 효과)

  • Kim, Gum Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.6
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    • pp.2880-2888
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    • 2013
  • This study determined the effectiveness of Doula Touch delivery education on self-confidence delivery, knowledge of childbirth and couple satisfaction. The experimental group(n=27) received the Doula Touch education at the public health center in the Y city of Gyeonggi Province from October of 2012 to November of 2012(four weeks). However, the control group(n=28) received the antenatal care at a D hospital in the W city of the same province from October of 2012 to November of 2012, but did not receive the Doula Touch education. The following are the results derived from the study. The experimental group significantly showed more self-confidence for delivery than the control group(t=-2.81, p=.007). Besides, the experimental group significantly showed more knowledge of childbirth than the control group(t=3.50, p=.001) but there was no significant difference in couple satisfaction between two groups (t=0.23, p=.8181). On the other hand, the study showed a high correlation between self-confidence of delivery and couple satisfaction(r=314, p=.005).