• Journal of applied mathematics & informatics
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• v.38 no.1_2
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• pp.189-200
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• 2020

Let G be a simple connected graph with n vertices and m edges. Denote by d₁ ≥ d₂ ≥ ⋯ ≥ d_n > 0 and d(e₁) ≥ d(e₂) ≥ ⋯ ≥ d(e_m) sequences of vertex and edge degrees, respectively. If vertices v_i and v_j are adjacent, we write i ~ j. The general sum-connectivity index is defined as 𝒳_α(G) = ∑_i~j(d_i + d_j)^α, where α is an arbitrary real number. Firstly, we determine a relation between 𝒳_α(G) and 𝒳_α-1(G). Then we use it to obtain some new bounds for 𝒳_α(G).

• Bulletin of the Korean Chemical Society
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• v.34 no.4
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• pp.1232-1236
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• 2013

The Cu cation binding sites of $[Cu(I){\cdot}d(CpG){\cdot}d(CpG)-2H]^{-1}$ complex have been investigated to explain the $[Cu{\cdot}DNA]$ biological activity caused by the Cu association to DNA. The structure of $[Cu(I){\cdot}d(CpG){\cdot}d(CpG)-2H]^{-1}$ complex was investigated by electrospray ionization mass spectrometry (ESI-MS). The fragmentation patterns of $[Cu(I){\cdot}d(CpG){\cdot}d(CpG)-2H]^{-1}$ complex were analyzed by MS/MS spectra. In the MS/MS spectra of $[Cu(I){\cdot}d(CpG){\cdot}d(CpG)-2H]^{-1}$ complex, three fragment ions were observed with the loss of d(CpG), {d(CpG) + Cyt}, and {d(CpG) + Cyt + dR}. The Cu cation binds to d(CpG) mainly by substituting the $H^+$ of phosphate group. Simultaneously, the Cu cation prefers to bind to a guanine base rather than a cytosine base. Five possible geometries were considered in the attempt to optimize the $[Cu(I){\cdot}d(CpG){\cdot}d(CpG)-2H]^{-1}$ complex structure. The ab initio calculations were performed at B3LYP/6-31G(d) level.

• Analytical Science and Technology
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• v.13 no.5
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• pp.624-629
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• 2000

A simple and rapid homogeneous enzyme-linked binding assay for mistletoe lectin I(ML I) was developed using a coupled enzyme system of malate dehydrogenase (MDH) and D-galactose. A highly substituted MDH-galactose conjugate was prepared by employing an isothiocyanate method for formation of thiourea bond. In the presence of ML I, ML I inhibits the activity of the conjugate based on the ML I/D-galactose specific interaction. Thus, the concentration of ML I can be related to the homogeneous inhibition of the MDH-galactose conjugate. Using this method. ML I can be measured at the level of microgram per milliliter within 10 minutes.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.2 s.33
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• pp.171-178
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• 2007

Objective : The aim of this study was to evaluate Yangdorak and D.I.T.I. for analysis of Symptom-complexes. Method : This study was selected 26 acne patients in Dongshin University Oriental Medical Hospital. We used Yangdorak (SME5800N, Sord Medicom Co., Korea) and D.I.T.I. (Digital Infrared Thermal Imaging 256, Dorex Inc, Orange CA, USA) and investigated the results of Yangdorak and D.I.T.I.. We made a comparison according to Deficiency or Excess(虛實) of acne patients. Result : In comparing Yangdorak results according to Deficiency or Excess(虛實) of acne patients, Triple-energizer(三焦), Intestine(大腸), Liver(肝), Stomach(胃) meridian in Excess group are higher than Deficiency group, and Kidney(腎) meridian in Deficiency group are lower than Excess group. D.I.T.I. reveald hyperthemia of face and chest on acne patients. The temperature of face and chest on Excess group is higher than Deficiency group. There is no statistically significant value compared with data of other group.

• International Journal of Precision Engineering and Manufacturing
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• v.6 no.4
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• pp.31-36
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• 2005

This paper describes a research work on the die design for the deep drawing & ironing(D. D. I) of high pressure gas cylinder. D. D. I die set is large-sized die used in horizontal press, which is usually composed of a drawing, and an ironing die. Design method of D. D. I die set is very different from that of conventional cold forging die set. Outer diameter of the die set is fixed because of press specification and that of the insert should be as small as possible for saving material cost. In this study, D. D. I die set has been designed to consider those characteristics, and the feasibility of the designed die has been verified by FE-analysis. In addition, the automated system of die design has been developed in AutoCAD R14 by formulating the applied methods to the regular rules.

• Journal of applied mathematics & informatics
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• v.30 no.1_2
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• pp.111-125
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• 2012

In this paper, we introduce new classes of generalized convex n-set functions called $d$-weak strictly pseudo-quasi type-I univex, $d$-strong pseudo-quasi type-I univex and $d$-weak strictly pseudo type-I univex functions and focus our study on multiobjective subset programming problem. Sufficient optimality conditions are obtained under the assumptions of aforesaid functions. Duality results are also established for Mond-Weir and general Mond-Weir type dual problems in which the involved functions satisfy appropriate generalized $d$-type-I univexity conditions.

• Archives of design research
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• no.16
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• pp.125-134
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• 1996

It IS timely and meaningful to research into the procedure of the establishment of the design movement and its role in early twentieth century Britain, which underwent a similar situation to that of current Korea, especially when the development of industrial design is thought to be essential in enhancing nation's competitive power. Besides, the study of the British design movement and design policies resulting from it will set a valuablt, example for us to follow in forming design policies for the betterment of design and in making guidelines for the Korean design movement. Therefore, first. I studil'd circumstances of the period when D.I.:\ was established and the German design movement as well as principles of German I}I.A. as foundation stones for it. Then. I discussed both D.I.A. activities and major figures of the D.I.A. movement in 1~):!O's, l~nO's and l~)~O's. In conclusion, I indicated [xJsitive and negative aspects of the role of D.l.:\.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.724-728
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• 2002

Angiotensin-converting enzyme (ACE) gene polymorphism, which consists of presence (insertion, I) or absence (deletion, D) of a 250-bp fragment, is associated with ischemic heart disease, renovascular disease, systemic lupus erythematosus. Subjects with the DD genotype have higher levels of circulating ACE than subjects with the II genotype and show an increased tendency towards vascular wall thickness and contribute to the development of vascular disease. But the association between I/D polymorphism of the ACE gene and cerebrovascular disease is still controversial. The aim of this study was to determine whether the DNA polymorphism of the ACE are associated with cerebrovascular disease in Korean population. The study group comprised 377 Korean patients admitted to Kyunghee Oriental Medical Center in the year of 2000 for the treatment of brain infarction or brain hemorrhage. Magnetic resonance imaging(MRI) was performed for each patient to determine the stroke phenotype, infarction or hemorrhage. The 183 subjects without evidence of brain infarction or brain hemorrhage were selected from the some ethnical population(control group). Venous blood samples were drawn from each subject for the extraction of DNA. Genotypes of ACE were determined by polymerase chain reaction amplification of the genomic DNA. Case and control genotype frequencies were compared by chi-square testing. Both the patients and the controls were classified respectively into 4 groups: age less than forty years, age forty one to fifty, age fifty one to sixty, age greater than sixty years. There were no significant differences in the distributions of ACE genotypes among the patients with infarction, with hemorrhage and controls (Infarction: D/D 15.8%, I/D 46.7%, I/I 37.5%, Hemorrhage: D/D 15.1%, I/D 46.5%, I/I 38.4%, Control: D/D 18.6%, I/D 50.3%, I/I 31.2%). There was a significant difference in the distribution of ACE genotypes between the age greater than sixty year subgroup of patient with brain hemorrhage and the control (Hemorrhage: D/D 0%, I/D 55.6%, I/I 44.4%, Control: D/D 13.0%, I/D 63.0%, I/I 23.9%; Pearson Chi-Square value 5.956, P<0.05). Furthermore, the frequency of the ACE D/D type declined with increasing age both in the patient and control group (Patient group: age < 50 D/D 21.5%, age > 50 D/D 14.42%; Control group: age < 50 D/D 21.0%, age > 50 D/D 14.2%). In conclusion there is no clear association between ACE polymorphism and cerebrovascular disease in Korean population. Although, there was a tendency for the frequency of the ACE D/D type declined with increasing age in both patients and controls.

• The Korean Journal of Pain
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• v.5 no.2
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• pp.199-205
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• 1992

• Journal of Technology Innovation
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• v.5 no.1
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• pp.181-205
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• 1997

There has been considerable controversy over the impacts of the tax credit on R&D expenditures in many countries. Korea has adopted various kinds of tax credit system to stimulate private firm' R&D expenditures. Korean government, Recently, is trying to reform tax system to reduce tax credit programmes according to Uruguay Round agreement and in line with OECD policy standards. The purpose of this paper is to analyze the effectiveness of current tax credit system on technology innovation in Korea and derive some policy implications over tax reform. In this paper, firstly, I investigate the size of tax reduction effects from each program in theoretical models and simulate the actual rate of individual tax incentive to a unit of R&D expenditure. I find that theoretically the reserve fund for technology development program has given the largest tax reduction effects to private firms irrespective of the R&D incentive system reform. Tax credit on R&D expenditure also has been very effective instrument to firm's tax reduction. Secondly, I try to measure the effectiveness of tax credit through the estimation of effective margianl tax rate between with the system and without the system of credit on R&D expenditure during the tax credit reform periods. I find that the tax credit on R&D has lowered firm's investment cost since the system introduced. I also have strong results that there has been a positive relation between the fluctuation of firm's R&D expenditure and the change of effective marginal tax rate. I suggest that it is better to sustain the system of tax credit on R&D for a while to increase firm's R&D expenditure.