• Title/Summary/Keyword: D-optimal Design

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Cheese Manufacturing and Bioactive Substance Separation: Separation and Preliminary Purification of cAMP from Whey

  • Liu, Yongfeng;Zhao, Xiaowei;Liu, Manshun;Zhao, Jing
    • Food Science of Animal Resources
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    • v.38 no.1
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    • pp.52-63
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    • 2018
  • Cheese consumption has been gradually increased in China. However, both the manufacturing process of cheese and the utilization of its main by-product were not well developed. Based on the sensory evaluation, Box-Behnken Design (BBD) was performed in the present study to optimize the cheese processing, which was proved more suitable for Chinese. The optimal parameters were: rennet 0.052 g/L, start culture 0.025 g/L and $CaCl_2$ 0.1 g/L. The composition analysis of fresh bovine milk and whey showed that whey contained most of the soluble nutrients of milk, which indicated that whey was a potential resource of cyclic adenosine-3', 5'-monophosphate (cAMP). Thus, the cAMP was isolated from whey, the results of high-performance liquid chromatography (HPLC) analysis showed that the macroporous adsorption resins (MAR) D290 could increase the concentration of cAMP from $0.058{\mu}mol/mL$ to $0.095{\mu}mol/mL$. We firstly purified the cAMP from the whey, which could become a new source of cAMP.

The Strength Analysis of Gears on Hydro-Mechanical Continuously Variable Transmission for Forklift (지게차용 기계유압식 무단변속기의 기어류에 대한 강도해석)

  • Bae, Myung Ho;Bae, Tae Yeol;Choi, Sung Kwang
    • Journal of Drive and Control
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    • v.13 no.4
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    • pp.45-51
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    • 2016
  • The power train of a hydro-mechanical, continuously variable transmission for forklifts makes use of hydro-static units, hydraulic multi-wet disc brakes & clutches, and complex helical & planetary gears. The complex helical & planetary gears are very important parts of the transmission because of a strength problem. In the present study, we calculated the specifications of the complex helical & planetary gear train, and analyzed the gear bending and compressive stresses of the gears. It is necessary to analyze the gear bending and compressive stresses thoroughly for optimal design of the complex helical & planetary gears with respect to cost and reliability. In this paper, we analyze the actual gear bending and compressive stresses of complex helical & planetary gears using the Lewes & Hertz equation, and we also verify the calculated specifications of the complex helical & planetary gears by evaluating the results of the data of allowable bending and compressive stress using the Stress vrs Number of Cycles curves of gears.

A Study of Sensing Locations for ECG Monitoring Clothing based on the Skin Change rate (체표 변화에 기반한 심전도 모니터링 의류의 센싱 위치 연구)

  • Cho, Hakyung;Cho, Sang woo
    • Fashion & Textile Research Journal
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    • v.17 no.5
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    • pp.844-853
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    • 2015
  • Recently, according to change of lifestyle and increase of concerning in health, needs of the smart clothing based on the vital sign monitoring have increased. Along with this trend, smart clothing for ECG monitoring has been studied various way as textile electrode, clothing design and so on. Smart clothing for ECG monitoring can become a comfortable system which enables continuous vital sign monitoring in daily use. But, smart clothing for ECG monitoring has a weakness on artifact during motion. One of the motion artifact caused by shifting of the electrode position was affected skin change by motion. The aim of this study was to suggest electrode locations for clothing of ECG monitoring to reduce of motion artifacts. Therefore, change of skin surface during the movement were measured and analyzed in order to find location to minimize motion artifacts in ECG monitoring clothing by 3D motion capture. For the experiment, the subjects consisted of 5 males and 5 females in their 20' with average physique. As a result, the optimal location for ECG monitoring was deducted under the bust line and scapula which have least motion artifact. These locations were abstracted to be least affected by movement in this research.

A STUDY ON FLOW MIXING IMPROVEMENT OF SELECTIVE CATALYTIC REDUCTION USING GASEOUS REDUCTANT (기상 환원제를 사용하는 선택적 환원촉매에서 유동혼합 개선에 관한 연구)

  • Ko, S.C.;Lee, B.H.;Cho, S.H.;Lee, S.H.;Hong, S.T.;Lee, D.Y.
    • Journal of computational fluids engineering
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    • v.15 no.1
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    • pp.56-63
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    • 2010
  • Since emission regulations for vehicles have become more stringent, SCR technology has drawn a strong attention in order to reduce NOx emissions. Optimal design of a reductant injection nozzle and a multi-hole plate located between the cone and catalyst is critical in that the uniform distribution of reductant is necessary to maximize the NOx conversion efficiency and minimize the slip of reductant in SCR. In this work, an LPG fuel(C3H8 in vapor state) was used as a reductant for LPG vehicles. A Realizable k-$\varepsilon$ model is used for turbulence, and SCR body is defined as porous media with inertia and viscous resistances measured in this work. Effect of the number of nozzle holes on the flow mixing index was analyzed, which revealed that a four hole nozzle shows the best performance in terms of uniformity of flow. An installment of a multi-hole plate at the entrance of catalyst was evaluated with flow mixing index, uniformity of flow, and pressure drop. A multi-hole plate with gradual hole diameter change in three steps showed the best uniformity of flow within the conditions suggested in this work.

Effect of Geometric Variation on Aerodynamic Characteristics of a Shrouded Tail Rotor (덮개꼬리로부터의 형상변화에 따른 공력 특성에 관한 연구)

  • Lee, H.-D.;Kang, H.-J.;Kwon, O.-J.
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.5
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    • pp.9-17
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    • 2005
  • In the early stage of helicopter design, an optimal configuration is usually determined after a numerous parametric study about the aerodynamic performance due to geometric variation. In order to improve the aerodynamic performance of a shrouded tail rotor, optimization of the tip clearance gap between blade and shroud, the blade planform shape, and the arrangement of blade spacing is required. In the present study, the aerodynamic performance characteristics of a shrouded tail rotor due to geometric variation was investigated by using an inviscid compressible unstructured mesh flow solver for rotary wings.

Optimization of the Ingredient Mixing Ratio for Preparation of Kiwifruit (Actinidia deliciosa) Jam Prepared with added Barley Sproutling Powder (어린 보릿잎을 첨가한 키위잼 재료 혼합비율의 최적화)

  • Jang, Myung-Sook
    • Korean journal of food and cookery science
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    • v.25 no.2
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    • pp.234-242
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    • 2009
  • This study was performed to find the optimum ratio of ingredients for the manufacture of kiwifruit jam. The experiment was designed according to the D-optimal design of RSM (response surface methodology), which included 18 experimental points with 4 replicates for three independent variables (sugar $35{\sim}60%$, pectin $0.1{\sim}1.0.%$, kiwifruit paste $0.37{\sim}0.90%$). The compositional and functional properties of the prepared products were measured, and these values were applied to mathematical models. A canonical form and trace plot showed the influence of each variable on the quality attributes of the final product mixture. By use of the F-test, viscosity, color values (L, a, b), and sensory characteristics (color) were expressed by a linear model, while the L color value and select sensory characteristics (smell, taste, overall acceptance) were also expressed by a quadratic model. The optimum formulations by the numerical and graphical methods, were similar, and with the numerical method it presented as: sugar, pectin, and barley sproutling powder at 49.7%, 0.5%, and 0.6%, respectively. The above results demonstrate the feasibility of preparing kiwifruit jam added with barley sproutling powder, and therefore, the commercialization of a kiwifruit jam marketed as a functional food is deemed possible.

The Study of Manufacturing Technology for a Sill Side by Roll Forming (다단 성형 기술을 이용한 차체 부품 개발)

  • Kim, D.K.;Han, S.W.;Jeon, H.J.;Cheon, S.H.;Moon, Y.H.
    • Transactions of Materials Processing
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    • v.23 no.6
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    • pp.376-379
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    • 2014
  • During roll forming a sheet metal is continuously and progressively formed into a product of the required cross-section and longitudinal shape. An example product is a circular tube with a required diameter, wall-thickness and straightness. Roll forming occurs by passing the sheet through a series of forming rolls that are arranged in tandem. Each pair of forming rolls in the roll forming line plays a particular role in obtaining the required cross-section and longitudinal shape in the product. In recent years, that process is often applied to car body parts by automotive industries. In the current study, an optimal model design and proper roll-pass sequences as well as the number of forming rolls and bending angles were used to produce a sill side. The effects of the process parameters on the final shape formed by roll forming defects were evaluated.

A Low-Power Portable ECG Touch Sensor with Two Dry Metal Contact Electrodes

  • Yan, Long;Yoo, Hoi-Jun
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.10 no.4
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    • pp.300-308
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    • 2010
  • This paper describes the development of a low-power electrocardiogram (ECG) touch sensor intended for the use with two dry metal electrodes. An equivalent ECG extraction circuit model encountered in a ground-free two-electrode configuration is investigated for an optimal sensor read-out circuit design criteria. From the equivalent circuit model, (1) maximum sensor resolution is derived based on the electrode's background thermal noise, which originates from high electrode-skin contact impedance, together with the input referred noise of instrumentation amplifier (IA), (2) 60 Hz electrostatic coupling from mains and motion artifact are also considered to determine minimum requirement of common mode rejection ratio (CMRR) and input impedance of IA. A dedicated ECG read-out front end incorporating chopping scheme is introduced to provide an input referred circuit noise of 1.3 ${\mu}V_{rms}$ over 0.5 Hz ~ 200 Hz, CMRR of IA > 100 dB, sensor resolution of 7 bits, and dissipating only 36 ${\mu}W$. Together with 8 bits synchronous successive approximation register (SAR) ADC, the sensor IC chip is implemented in 0.18 ${\mu}m$ CMOS technology and integrated on a 5 cm $\times$ 8 cm PCB with two copper patterned electrodes. With the help of proposed touch sensor, ECG signal containing QRS complex and P, T waves are successfully extracted by simply touching the electrodes with two thumbs.

Color Tunable Nanostructures by Polarization Control for Display Applications

  • Cho, Eun-Byurl;Ko, Yeong-Il;Yeo, Jong-Souk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.567-567
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    • 2013
  • Surface plasmon resonance is the enhancement of electromagnetic wave caused by oscillation on the metal and dielectric interfaces. Surface plasmons with nanohole arrays provides an enhancedresonance for the specific wavelengths of interests. Asymmetric array of nanoscale structures can enable orientation dependent shift of resonance wavelengths when combined with the control of polarization for incident visible light, thus providing color tunability. Appropriate lattice constants along the direction of polarization in rectangular nanohole arrays can determine the resonance condition generating red (R), green (G), and blue (B) colors and potentially be applied to display applications. In ourprevious report, we have optimized the ion beam nanomachining conditions to fabricate the nanostructures on the metal film. We apply the fabrication conditions to make nanoscale hole arrays using 100 nm thick gold layer on the glass substrate with the optimal design of periodicities along x, y, and diagonal directions of a=440 nm, b=520 nm, c=682 nm, and the hole diameter of d=200 nm. Using the reflective light in dark field mode of optical microscope, we can observe different colors. When the polarizer is paralleled along a, b, or c direction, the represented color is changed to R, G, and B, respectively. We further map the color using i1 to correlate the conditions of the nanohole arrays with their characteristic color.

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Velocity and Spray Characteristics under Swirl Flows in a Model Combustor (모델연소기 선회유동장에서의 속도 및 분무특성)

  • Bae, C.S.;Lee, D.H.
    • Journal of ILASS-Korea
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    • v.3 no.2
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    • pp.42-50
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    • 1998
  • The effect of swirl flows un the fuel spray characteristics were investigated for various swillers in a model combustor. The interaction between the flow field and fuel spray in the main combustion tone made by frontal devices including fuel injection nozzles and swirlers. which were characterized by flow velocities, fuel droplet sizes and their distributions which were measured by APV(Adaptive Phase/Doppler Velocimetry) under atmospheric condition at 320cc/min kerosine fuel flow and 0.04kg/sec air supply. A dual swirler with circumferential two-stage swirl vanes of $40^{\circ}\;and\;45^{\circ}$ vanes in different directions and two single-stage swillers of $40^{\circ}$ vanes with 12 and 16 vanes were tested. It was found that the dual swirler has the largest recirculating zone with highest reverse flow velocity. The strongest swirl flow was found at the boundary of recirculation zone. Small fuel droplets were observed in the main axial stream and inside the recirculation zone when swirling flow field were generated by the frontal devices. These findings could give the tips on the optimal design of frontal devices to realize low emissions in gas turbine combustion.

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