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Non-radiologic Methods for Predicting Vesicoureteral Reflux in Childhood Urinary Tract Infection (요로감염 환아에서 비방사선학적 방법에 의한 방광요관역류의 조기 예측에 관한 연구)

  • Jeon Seong-Hoi;Lee K.C.;Yoo Kee-Hwan
    • Childhood Kidney Diseases
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    • v.1 no.1
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    • pp.38-45
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    • 1997
  • Purpose : Vesicoureteral reflux(VUR) in childhood may be the primary cause of recurrent urinary tract infection and renal scarring. Renal ultrasonography, DMSA, and voiding cystourethrogram are the standard clinical methods for detection of vesicoureteral reflux. But these methods have many disadvantages such as invasiveness and high cost. So, we studied to observe the significance of urine ${\beta}_2$-microglobulin in association with other non-radiologic methods for predictng vesicoureteral reflux. Methods : We evaluated 40 patients with urinary tract infection who were admitted to Korea university Hospital from July 1993 to June 1994. Among them, 24 patients revealed urinary tract infection and vesicoureteral reflux(group A), 16 patients revealed only urinary tract infection(group B). Both groups were compared by presence of fever, hematuria, and proteinuria, positivity of CRP, and level of BUN, Cr, GFR by 99mTc-DTPA, urine ${\beta}_2$-microglobulin, 24 hours urine albumin. Results : 1) Among 24 patients who had vesicoureteral reflux, 14 had unilateral VUR, 10 had bilateral VUR, three kidneys with grade I, nine with grade II, eleven with grade III, eleven with grade IV by classification of International Reflux Study Committee. Among them, 14 patients had renal scar, five with type A, five with type B, four with type C, none with type D by Smellie's classification. 2) The mean of GFR, BUN, Cr, 24hrs urine albumin and the presence of hematuria and proteinuria showed no significant difference between group A and group B. The mean of urine ${\beta}_2$ microglobulin in group A and group B were $283.6{\pm}195.8{\mu}g/l$ and $78.7{\pm}48.5{\mu}g/l$ respectively, showing that group A had a higher value than group B (p<0.01). In case of ${\beta}_2$ microglobulin > $120{\mu}g/l$ and CRP(+), the sensitivity was 93.3% and the specificity is 77.8% for detecting of VUR. In case of ${\beta}_2$-microglobulin>$120{\mu}g/l$ and fever(+), the sensitivity was 92.2%, and the specificity was 62.5% for detecting of VUR Conclusions : If the level of urinary ${\beta}_2$-microglobulin is more than 120ug/l in children with urinary tract infection in association with fever(+) or CRP(+), it can predict VUR. So we can use it for early detection of VUR.

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Effects of Dietary Effective Microorganism (EM) on Growth Performance, Microflora Population and Noxious Gas Emission in Broiler (유용 미생물 첨가가 육계 생산성, 맹장 내 균총 및 유해가스 발생량에 미치는 영향)

  • Kang, Hwan Ku;Kim, Chan Ho;Bang, Han Tae;Kim, Ji Hyuk;Kim, Min Ji;Kim, Dong Woon;Na, Jae Cheon;Hwangbo, Jong;Yang, Young Rok;Choi, Hee Cheol;Moon, Hong Kil
    • Korean Journal of Poultry Science
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    • v.41 no.4
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    • pp.227-233
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    • 2014
  • This study investigated the effects of dietary supplementation with the effective microorganism (EM) on the growth performance, blood parameter, small intestinal microflora, and noxious gas emission of broilers. A total 720 1-d old ROSS 308 was randomly assigned to 6 dietary treatment groups: control, virginiamycin (6 mg/kg), 0.1% PB 0.1% EM, 0.5% EM, and 1.0% EM. Each treatment was fed to 4 replicates of 30 birds per diet for d 35. Two-phase feeding program with a starter diet from 0 to 3 wk, and a finisher diet from 4 to 5 wk was used in the experiment. Within each phase, a diet was formulated to meet or exceed NRC requirements of broilers for macro- and micronutrients. The diet and water were available ad libitum. Result indicated that during overall periods of the experiment, final weight, body weight gain, and feed intake were not different among dietary treatments. Feed conversion ratio was less (P<0.05) for EM treatments than control, antibiotics, and PB. Total cholesterol (TC), triglyceride (TRG), glucose (GLU), total protein (TP), calcium (CA), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were not different among dietary treatments. White blood cell (WBC), hemoglobin (Hb), heterophils (HE), lymphocyte (LY), monocytes (MO), and eosinophils (EO) were not different among dietary treatments. HE:LY was less (P<0.05) for EM0.5 treatments than control, antibiotics, and PB. Lactobacillus was greater (P<0.05) for EM treatments than control and antibiotics. E. coli and Salmonella were not different among dietary treatments. $NH_3$ and $CO_2$ wereless (P<0.05) for EM treatments than control. These results indicated that EM treatments were effective feed conversion ratio, noxious gas emission and micro flora population on the cecum in broilers.

Study on verification of various national standards regarding phthalate testing in industrial products (공산품 중 프탈레이트류 함유량 분석법에 관한 국내외 표준의 검증 연구)

  • Song, Moon-Hwan;Cho, Young-Dal;Choe, Eun-Kyung;Myoung, Young-Chan
    • Analytical Science and Technology
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    • v.25 no.3
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    • pp.178-189
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    • 2012
  • As phthalates classified as toxic to reproduction category 2 and endocrine disrupting chemicals were more strictly regulated as Substances of Very High Concern (SVHC) for authorization in under EU REACH and considered as priority substances in RoHS II, standardization of phthalate testing method is now being proposed in IEC 62321 of IEC TC 111 and the 2nd revision of KS M 1991 is also finished. In order to assist standardization activities related to phthalating testing, solvent extraction part of existing national standards were compared and verified. Recovery of DEHP (diethylhexyl phthalate) from PVC (polyvinyl chloride) by Soxhlet extraction increased in the order of methanol, toluene, dichloromethane and hexane from 46.9% to 95.3% as measured by GC-MS. Optimum extraction time was verified to be 6 hours using hexane. Recovery of DBP (dibutyl phthalate), BBP (butylbenzyl phthalate), and DEHP from different matrixes such as PVC, nitro cellulose, ABS (acrylonitrile butadiene styrene). and EPDM(ethylene propylene diene monomer) rubber were evaluated to be more than 90% up to 99%. The detection limits of phthalates in solvent extraction followed by GC-MS analysis were 0.08~0.3 ${\mu}g/mL$ in solution and 8~30 mg/Kg in polymeric samples. GC-MS analyses of phthalates were carried out using different solvent extraction based on the EN 14372, ASTM D 7083, Japanese test method (MHLW 0906-4) and KS M 1991, proving that equivalent recoveries ranging from 98%~99% were obtained. DBP and DEHP were detected in three consumer products such as a child toy, a power cable and manicure with the amount of 22~1,910 mg/kg.

Calculation of Renal Depth by Conjugate-View Method Using Dual-head Gamma Camera (이중 헤드 감마 카메라를 이용한 Conjugate-View 계수법에 의한 신장 깊이 도출)

  • Kim, Hyun-Mi;Suh, Tae-Suk;Choe, Bo-Young;Chung, Yong-An;Kim, Sung-Hoon;Chung, Soo-Kyo;Lee, Hyoung-Koo
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.6
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    • pp.378-388
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    • 2001
  • Purpose: In this study, we developed a new method for the determination of renal depth with anterior and posterior renal scintigrams in a dual-head gamma camera, considering the attenuation factor $e^{-{\mu}x}$ of the conjugate-view method. Material and Method: We developed abdomen and kidney phantoms to perform experiments using Technetium-99m dimercaptosuccinic acid ($^{99m}Tc$-DMSA). The phantom images were obtained by dual-head gamma camera equipped with low-energy, high-resolution, parallel-hole collimators (ICONf, Siemens). The equation was derived from the linear integration of omission ${\gamma}$-ray considering attenuation from the posterior abdomen to the anterior abdomen phantom surface. The program for measurement was developed by Microsoft Visual C++ 6.0. Results : Renal depths of the phantoms were derived from the derived equations and compared with the exact geometrical values. Differences between the measured and the calculated values were the range of 0.1 to 0.7 cm ($0.029{\pm}0.15cm,\;mean{\pm}S.D.$). Conclusion: The present study showed that the use of the derived equations for renal depth measurements, combined with quantitative planar imaging using dual-head gamma camera, could provide more accurate results for individual variation than the conventional method.

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Effects of Some Factors on In Vitro Production of Embryos from Antral Follicle-Derived Porcine Oocytes II. Effects of EGF and the Number of COCs into Maturation Media on In Vitro Maturation, Fertilization and Development (돼지 난포란 유래 체외수정란 생산에 대한 제요인의 영향 II. 체외성숙배양시 EGF와 COC의 수가 체외성숙, 체외수정 및 체외발달에 미치는 영향)

  • Yeon, S.-H.;Son, D.-S.;Han, M.-H.;Wee, M.-S.;Choi, S.-H.;Lee, K.-S.
    • Journal of Embryo Transfer
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    • v.19 no.2
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    • pp.173-183
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    • 2004
  • This study was carried out to examine the effects of epidermal growth factor (EGF) and the number of cumulus-oocyte complexes (COCs) on in vitro maturation (IVM) of porcine immature oocytes, and on subsequent in vitro fertilization (IVF) and development (IVD). COCs were collected from antral follicles of porcine ovaries collected from abattoir, and were maturated in modified NCSU-23 (mNCSU-23) with 10% pFF, 0.6 mM cysteine, 50 ${\mu}mM{\beta}-mercaptoethanol$, 1 mM dbcAMP, 10 IU/mL PMSG and 10 IU/mL hCG, which was supplemented with or without 10 ng/mL EGF and into which 50 or 15 COCs per droplet was put. Oocytes matured in vitro, were fertilized in vitro in modified Tris-buffered medium (mTBM) with the final motile sperm concentration of 1${\times}$105 sperm/mL, and subsequently putative embryos were developed in vitro in NCSU- 23. The results are as follows. 1.In the result of IVM, 10 ng/mL EGF supplement duplicated the percentage of C4 group of COCs(41% vs 81%). But the rate of germinal vesicle breakdown (GVBD) and of nuclear maturation were not significantly different between control and EGF supplemented, or between the number of COCs per culture droplet, and there was not a significant interaction between the two factors, either. 2. In the result of IVF, there was not significantly different between control and EGF supplemented, or between the number of COCs per culture droplet, or was not a significant interaction between the two factors, in the rate of sperm penetration, in the percentage of oocytes with male pronucleus (MPN), and in the rate of polyspermy. 3. In the result of IVD, there was not significantly different between control and EGF supplemented, or between the number of COCs per culture droplet in the percentage of cleaved oocytes. There was not significantly different between the number of COCs per culture droplet, but between control and EGF supplemented (p<0.01) in the percentage of blastocysts, the number of inner cell mass (ICM), trophectoderm (TC) and total cells. There was no significant interaction between the two factors anywhere. These results suggested that 10 ng/mL EGF supplement into mNCSU-23 for IVM was effective in the production of more as well as better blastocysts during IVD through increasing the number of cells in those.

Detection of Spinal Metastases: Comparison of Bone Scan and MR Imaging (전이성 척추 악성 종양의 진단 : 골스캔과 자기공명영상의 비교)

  • Kim, Ki-Jun;Sohn, Hyung-Sun;Park, Jeong-Mi;Chung, Soo-Kyo;Lee, Jae-Moon;Kim, Choon-Yul;Bahk, Yong-Whee;Shinn, Kyung-Sub
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.384-390
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    • 1994
  • Authors retrospectively compared the 99mTc MDP bone scans and corresponding MR imagings in 20 patients with histologically proven malignancy, Mean interval of the two studies was 16.6 days, Cancer diagnosis Included 8 lung, 2 each of colon, breast, stomach, 1 each of prostate, thyroid, malignant lymphoma and 3 adenocarcinoma of unknown primary site. Of the 105 regions compared, :t6 regions were positive for metastases in bone scans or MR imagings. 30 regions(65.2%) were positive by bone scan and 44 regions(95.7%) by MR imaging. 87 regions(82.9%) were concordantly positive or negative by bone scan and MR imaging, but 18 regions(17.1%) were discordant. In the discordant regions, 16 regions positive in MR imaging were negative in bone scan. The greatest number of discordant findings occured in the cervical region and in the patient with stomach cancer. Our results suggest that the sensitivity of MR Imaging is greater than that of bone scan in detecting spinal metastases. And bone scan is useful screening test of metastasis for evaluating entire skeleton including spine.

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Characterization of Wireless Feedback Interference Channels of a Wireless Repeater Using Sounding Measurements (무선 중계시스템의 무선 궤환 간섭 채널 측정 및 특성 분석)

  • Moon, Woo-Sik;Im, Sung-Bin;Kim, Hyun-Chae;Kwon, Nag-Won
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.1
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    • pp.40-47
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    • 2009
  • This paper presents the method of measuring the feedback interference channel, which is developed between the transmit and receive antennas of a wireless repeater by receiving the transmit signal at the receive antenna of the identical repeater, and experiment results obtained by analyzing the measurements. This experiment uses 2 GHz WCDMA signal and is carried out near a highway. The high-speed mobiles on highways cause reflected signals with high Doppler frequencies and large energy. In order to characterize the feedback channel, the power delay profile and the scattering function are estimated by identifying the delay spread, the Doppler spread, the number of fingers, and the attenuation with delay. Since the feedback interference channel is constructed between the fixed TX and RX antennas, which is dependent upon the multipaths developed by moving or fixed objects around the antennas, the channel shows different properties comparing to the conventional channels between the base station and the mobile station. Therefore, the results presented in the paper are expected to provide guidelines for designing and evaluating wireless repeater systems.

Fabrication of a High-performance Oscillator with a Tunable High-Q HTS $YBa_2Cu_3O_{7-\delta}$ Resonator (High-Q $Yba_2Cu_3O_{7-\delta}$ 고온초전도체 공진기를 이용한 주파수 튜닝이 가능한 고성능 발진기 제작)

  • Yang Woo Il;Lee Jae Hun;Hur Jung;Lee Sang Young
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.42 no.7 s.337
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    • pp.63-70
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    • 2005
  • We investigated the phase noise of an oscillator with a extremely high-Q resonator used as the resonant element. A TE$_{011}$ mode rutile-loaded resonator with high-temperature superconductive (HTS) $YBa_2Cu_3O_{7-\delta}$(YBCO) films used as the endplates is prepared for this purpose. At 23.5 K, the unloaded Q and the loaded Q are 863000 and 180000, respectively. The phase noise of -104.8 dBc/Hz at 1 KHz offset was observed for the oscillator having a resonator with $Q_{L}$ =180000 at the $TE_{01\delta$ mode resonant frequency of 8.545 GHz at 23.5 K Such oscillators with very low phase noise are expected to be used for building up communication systems capable of efficient use of the frequency band and high-speed data transmission as well as for Doppler radars. Frequency tuning could be realized for the resonator by using a piezoactuator Applicability of the tunable rutile resonator for fabricating tunable oscillators of high performances is discussed.

Low Phase Noise VCO Using Novel Harmonic Control Circuit Based on Composite Right/Left-Handed Transmission Line (혼합 우좌향 전송 선로 기반의 새로운 고조파 조절 회로를 이용한 저위상 잡음 전압 제어 발진기)

  • Choi, Jae-Won;Seo, Chul-Hun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.1
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    • pp.84-90
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    • 2010
  • In this paper, a novel voltage-controlled oscillator (VCO) using the harmonic control circuit based on the composite right/left-handed (CRLH) transmission lines (TLs) is presented to reduce the phase noise without the reduction of the frequency tuning range and miniaturize the circuit size. The phase noise is reduced by the novel harmonic control circuit having the short impedances for the second- and third-harmonic components. The proposed harmonic control circuit is designed by using the CRLH TLs with the dual-band characteristic by the frequency offset and phase slope of the CRLH TLs. The high-Q resonator has been used to reduce the phase noise, but has the problem of the frequency tuning range reduction. However, the frequency tuning range of the proposed VCO has not been reduced because the phase noise has been reduced without the high-Q resonator. The miniaturization of the circuit size is achieved by using the CRLH TLs instead of the conventional right-handed (RH) TLs. The phase noise of VCO is -119.17 ~ -117.50 dBc/Hz at 100 kHz in the tuning range of 5.731 ~ 5.938 GHz.

Improvement of the Adaptive Modulation System with Optimal Turbo Coded V-BLAST Technique using STD Scheme (선택적 전송 다이버시티 기법을 적용한 최적의 터보 부호화된 V-BLAST 적응변조 시스템의 성능 개선)

  • Ryoo, Sang-Jin;Choi, Kwang-Wook;Lee, Kyung-Hwan;You, Cheol- Woo;Hong, Dae-Ki;Hwang, In-Tae;Kim, Cheol-Sung
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.44 no.2
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    • pp.6-14
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    • 2007
  • In this paper, we propose and observe the Adaptive Modulation system with optimal Turbo Coded V-BLAST (Vertical-Bell-lab Layered Space-Time) technique that is applied the extrinsic information from MAP (Maximum A Posteriori) Decoder in decoding Algorithm of V-BLAST: ordering and slicing. The extrinsic information is used by a priori probability and the system decoding process is composed of the Main Iteration and the Sub Iteration. And comparing the proposed system with the Adaptive Modulation system using conventional Turbo Coded V-BLAST technique that is simply combined V-BLAST with Turbo Coding scheme, we observe how much throughput performance has been improved. In addition, we observe the proposed system using STD (Selection Transmit Diversity) scheme. As a result of simulation, Comparing with the conventional Turbo Coded V-BLAST technique with the Adaptive Modulation systems, the optimal Turbo Coded V-BLAST technique with the Adaptive Modulation systems has better throughput gain that is about 350 Kbps in 11 dB SNR range. Especially, comparing with the conventional Turbo Coded V-BLAST technique using 2 transmit and 2 receive antennas, the proposed system with STD (Selection Transmit Diversity) scheme show that the improvement of maximum throughput is about 1.77 Mbps in the same SNR range.