• Parasites, Hosts and Diseases
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• 제23권2호
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• pp.269-284
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• 1985

The metabolism of Entamoeba histolytica would be affected by various environmental factors, and alteration of the environment was known to afEect the fine structure of 5. histolytica. The present study was designed electronmicroscopically to investigate the ultrastructure and enzyme activities in the aEonic and conventional strains of 5. histolytica. The trophozoites of axenically cultivated HK-9 strain and conventional YS-27 and YS-49 strains of 5. histolytica were collected and liKed with 4% paraformaldehyde/0.1M cacodylate buffier(pH 74), After washing them by centrifugation, 1% warm agar was added in the sediment. Solidified agar with the trophozoites was cut into $lmm^3$ cubes, and incubated in the various substrates to observe enzyme activities. Then, the specimen was post-fixed with 3% glutaraldehyde/0.1M cacodylate buffer (PH 7.4) and 1% osmium tetroBide/0.1M cacodylate buffier (pH 7.4) , dehydrated in ascending ethanol series and embedded in epoxy resin. These were sectioned on an ultramicrotome and observed with a transmission electronmicroscope. The procedures for the observation of the fine structure were same as the above, except for the incubation in the substrate. The sections were stained with uranyl acetate and lead citrate. For the observation of the surface of the amoebae, scanning-electronmicroscopy was carried out. The results obtained in the present study are summarized as follows: 1. The fuzzy coat around double-layered plasma membrane of 5. histolytica was more irregularly and densely distributed in the conventional strains (YS-27, YS-49 strains) than in the axonic strain (HK-9 strain). 2. The endosomes, button bodies and chromatin material were surrounded by a double-layered nuclear membrane having scattered nuclear fores. The paranuclear body, mono- or double-layered vacuoles, vacuolar membrane whorls, rosette-like cylindrical bodies, aggregation of cylindrical bodies and helical bodies were found in the cytoplasm of the amoebae. Helical bodies and glycogen granules were generally abundant, while a few smooth endoplasmic reticula were observed in the cytoplasm. 3. Alkaline phosphatase activity was mainly demonstrated in the plasma membrane, limiting membranes of vacuoles and smooth endoplasmic reticula. ATPase activity was observed in the nucleus, limiting membranes of vacuoles and vacuolar membrane whorls. 4. Acid phosphatase activity was commonly demonstrated in the limiting membranes an contents of vacuoles, Iysosome-like organelles, plasma membrane and the button bodies in the nucleus. The activity was more weakly demonstrated in the HK-9 strain than in the other conventional strains of 5. histolytica. No peroBidase activity was observed in the amoeba strains employed in the present study. 5. With a scanning electron-microscope, no distinct structural differences were observed between the amoeba strains. All the trophozoite forms of the amoebae showed crater-like depressions and rugged features on the outer surface.

• 대한소아치과학회지
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• 제38권3호
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• pp.250-259
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• 2011

본 연구의 목적은 소아 청소년의 얇은 피질골에서 안정성을 가지는 미니스크류 디자인을 제시하고자 하는 것이다. 직경, 길이, 몸체모양을 달리한 교정용 미니스크류를 피질골의 두께를 달리한 두 종류의 인조골 시편에 식립하여 최대 식립 토크, 최대 제거 토크 및 측방 변위 토크를 측정하였다. 연구결과 피질골의 두께 및 미니스크류의 직경, 길이, 몸체모양은 모두 최대 식립 토크, 최대 제거 토크, 측방 변위 토크에 유의한 영향을 미쳤다. 피질골의 두께가 가장 중요한 요소로 나타났으며 원추형이 원통형보다 초기 고정력이 우수하고, 직경이 증가할수록 역학적 고정력 확보에 유리하였다. 길이의 증가는 다른 요소에 비해 초기 고정력 확보에 미치는 영향이 크지 않으나 6 mm와 8 mm는 고정력 확보에 통계적으로 유의한 차이가 있었다(p<0.05). 피질골이 얇은 소아 청소년의 골에서 미니스크류의 안정성은 원추형, 직경 1.8 mm가 유리하며, 길이도 6 mm 보다는 8 mm가 유리하다.

• 에너지공학
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• 제10권3호
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• pp.223-232
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• 2001

보염기 후류에 형성되는 화산회생의 보염특성을 고찰하기 위하여 연료 분출각의 변화, 난류발생격자의 설치, 재순환영역 내에 보조 연료의 공급에 따른 화염의 안정범위, 재순환영역의 길이 및 온도, 재순환영역주변의 난류강도 분포를 측정, 고찰하였다. 재순환영역의 길이는 주 연료 분출량의 변화에 따른 영향을 받지 않지만, 연료 분출각 및 주류유속의 변화, 보조 연료의 공급 난류발생격자의 설치 등에 따라 영향을 받는다. 확산화염의 경우 일반적으고 재순환영역의 길이가 길수록 보염성이 불량하지만, 난류발생격자를 설치한 경우에는 재순환영역의 길이가 길수록 보염성이 양호하다. 재순환영역의 온도는 연료 분출각의 변화, 보조 연료의 공급, 난류발생격사의 설치 등에 따라 영향을 받으며, 이론 혼합기 상태에서 최고값에 도달한다. 일반적으로 재순환영역의 온도가 낮을수록 보염성이 양호하지만. 난류발생격자를 설치한 경우에는 재순환영역의 온도가 낮을수록 보염성이 불량하다. 화염이 형성되는 보염기 후류 영역에 대한 난류강도는 격자의 직경이나 구속비가 큰 난류발생 격자를 설치한 경우에 크게 나타나며, 난류강도가 강 할수록 보염성이 불량하다. 연료 분출각의 변화, 난류발생격자의 설치, 재순환영역 내에 보조 연료의 공급 등의 방법으로 확산화염의 보염특성을 제어할 수 있다.

• Journal of Radiation Protection and Research
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• 제38권4호
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• pp.194-201
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• 2013

To investigate monitoring unit (MU) efficiency and plan quality of volumetric modulated arc therapy (VMAT) using flattening-filter free (FFF) photon beam in association with target size and location. A virtual patient was generated in Eclipse$^{TM}$ (ver. A10, Varian Medical Systems, Palo Alto, USA) treatment planning system. The length of major and minor axis in axial view was 50 cm and 30 cm, respectively. Cylindrical-shaped targets were generated inside that patient at the center (symmetric target) and in the periphery (asymmetric target, 7.5 cm away from the center of the patient to the right direction) of the virtual patient. The longitudinal length was 10 cm and the diameters were 2, 5, 10 and 15 cm. Total 8 targets were generated. RapidArc$^{TM}$ plans using TrueBeam STx$^{TM}$ were generated for each target. Two full arcs were used and the axis of rotation of the gantry was set to be at the center of the virtual patient. Total MU, homogeneity index (HI), target mean dose, the value of gradient measure and body mean dose were calculated. In the case of symmetric targets, averaged total MU of FFF plan was 23% and 19% higher than that of flattening filter (FF) plan when using 6 MV and 10 MV photons, respectively. The difference of HI, target mean dose, gradient measure and body mean dose between FF and FFF was less than 0.04, 2.6%, 0.1 cm and 2.2%, respectively. For the asymmetric targets, total MU of FFF plan was 21% and 32% was higher than that of FF when using 6 MV and 10 MV photons, respectively. The homogeneity of the target was always worse when using FFF than using FF. The maximum difference of HI was 0.22. The target mean dose of FFF was 3.2% and 4.1% higher than that of FF for the 6 MV and 10 MV, respectively. The difference of gradient measure was less than 0.1 cm. The body mean dose was higher when using FFF than FF about 4.2% and 2.8% for the 6 MV and 10 MV, respectively. No significant differences between VMAT plans of FFF beam and FF beam were observed in terms of quality of treatment plan. The HI was higher when using FFF 10 MV photons for the asymmetric targets. The MU was increased noticeably when using FFF photon beams.

• 한국의학물리학회지:의학물리
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• 제23권4호
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• pp.252-260
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• 2012

최근 Computed tomography (CT) 조사선량의 인체에 대한 부정적 영향이 부각됨에 따라 선량을 줄이는 연구가 활발히 진행되고 있고, 이로 인하여 소 동물에 관한 연구는 점점 임상전의 연구로서 필수적으로 여겨지고 있다. 최근에는 피폭 선량을 줄일 수 있는 방법으로서 이론적으로 투영 데이터가 충분하지 않을 때 정확하게 영상을 재구성 하는 것이 가능한 Total Variation (TV) minimization 알고리즘이 각광받고 있다. 이에 본 연구에서는 micro-CT (DRGem, Harmony80H series, Korea) 시스템에서 획득한 적은 수의 투영 데이터를 가지고 TV minimization에 기초한 반복적 영상 재구성 알고리즘과 기존의 Feldkamp-Davis-Kress (FDK) 알고리즘을 사용하여 영상을 재구성하고 두 알고리즘의 영상 화질을 비교 및 평가하였다. TV minimization 알고리즘의 효과를 평가하기 위해서, 먼저 서로 다른 농도의 조영제, 물, 공기가 들어있는 원통형 팬톰을 제작하였고, micro-CT를 사용하여 영상을 획득하였다. Tube와 검출기 일회전 당 최대 400개의 투영 데이터를 획득할 수 있으며, TV minimization 알고리즘의 영상 복원의 정도를 평가하기 위해서 20, 50, 90, 180장의 적은 투영 데이터를 추출하였다. 영상 비교평가를 위한 참고 영상(FDK-reference 영상)은 마찬가지로 400개의 투영데이터를 이용하여 FDK 알고리즘으로 재구성하였고, 20, 50, 90, 180장의 투영데이터를 가지고 TV minimization 알고리즘, FDK 알고리즘을 이용하여 재구성한 영상과 FDK-reference 영상의 프로파일, Contrast-to-noise ratio (CNR), Universal quality index(UQI)를 각각 비교평가 하였다. 또한, 소 동물에 관한 연구를 위하여 mouse 영상에 관하여 프로파일과 UQI를 분석하여 비교평가 하였다. 결과적으로 90개의 투영데이터를 사용하여 재구성한 원통형 팬톰 영상을 분석하였을 때, TV minimization 영상(TV-90) 및 FDK 영상(FDK-90)의 CNR과 UQI를 비교하였을 때 FDK-90보다 TV-90에서 CNR이 0.21, UQI가 0.18 증가하였다. 원통형 팬톰 영상과 같은 조건에서 mouse 영상을 사용하였을 때, UQI는 FDK-90보다 TV-90에서 0.08 증가하였다. 결론적으로 본 연구결과는 기존의 micro-CT의 투영 데이터의 사분의 일이 되는 투영데이터를 사용하여 영상을 재구성하여 비교평가 한 결과 투영영상 데이터의 수가 제한되는 경우에 FDK 알고리즘보다 TV minimization 알고리즘이 X-ray 조사시간을 줄임으로서 피폭선량을 줄이는데 효과적으로 기여할 것으로 기대된다. 특히, 조사시간의 단축은 물체의 움직임으로 인한 영상 화질의 저하를 감소시키는데 기여할 것으로 사려된다.

• 한국농공학회지
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• 제30권3호
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• pp.82-94
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• 1988

A growing attention has been paid to the optimum design of structures in recent years. Most studies on the optimum design of reinforced concrete structures has been mainly focussed to the design of structural members such as beams, slabs and columns, and there exist few studies that deal with the optimum design of large-scale concrete shell structures. The purpose of the present investigation is, therefore, to set up an efficient optimum design method for the large-scale reinforced concrete cylindrical shell structures like intake tower of reservoir. The major design variables are the dimensions and steel areas of each member of structures. The construction cost which is compo8ed of the concrete, steel, and form work costs, respectively, is taken as the objective function. The constraint equations for the design of intake-tower are derived on the basis of strength design method. The results obtained are summarized as follows 1. The efficient optimlzation algorithrns which can execute the automatic optimum design of reinforced concrete intake tower based on the strength design method were developed. 2. Since the objective function and design variables were converged to their optimum values within the first or second iteration, the optimization algorithms developed in this study seem to be efficient and stable. 3. When using the strength design method, the construction cost could be saved about 9% compared with working stress design method. Therefore, the reliability of algorithm was proved. 4. The difference in construction cost between the optimum designs with substructures and with entire structure was found to be small and thus the optimum design with substructures may conveniently be used in practical design. 5. The major active constraints of each structural member were found to be the 'bending moment constraint for slab, the minimum longitudinal steel ratio constraint for tower body and the shearing force, bending moment and maximum eccentricity constraints for footing, respectively. 6. The computer program developed in the present study can be effectively used even by an uneiperienced designer for the optimum design of reinforced concrete intake-tower on the basis of strength design method.

• Parasites, Hosts and Diseases
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• 제51권4호
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• pp.441-448
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• 2013

This study describes the first record of Bourgelatia diducta (Nematoda: Chabertiidae) from wild boars in the Republic of Korea (=South Korea). Gastrointestinal tracts of 87 Korean wild boars (Sus scrofa coreanus) hunted in mountains in the south-western part of South Korea between 2009 and 2012 were examined for their visceral helminths. B. diducta, as identified by morphological characteristics of the head and tail, were recovered from the large intestine of 47 (54%) wild boars. The average length of adult female worms was $11.3{\pm}0.872$ mm and the thickest part of the body measured $0.54{\pm}0.04$ mm in maximum width, while those of males were $9.8{\pm}0.72$ and $0.45{\pm}0.03$ mm, respectively. The characteristic J-shaped type II ovejector was observed in females, and the type II dorsal ray with 2 rami on each side of the median fissure was uniquely seen in males. The buccal capsule was small, relatively thin-walled, cylindrical, very short, and ring-shaped. The externodorsal ray arose from a common stem with the dorsal ray. The cervical groove was absent. The anterior extremity was equipped with 20-22 external corona radiata, 4 cephalic papillae and 2 lateral amphids around the mouth. The eggs were $66.0{\times}38.9{\mu}m$ in average size. By the present study, B. diducta (Nematoda: Chabertiidae) is recorded for the first time in South Korea. Additionally, morphological characteristics and identification keys provided in the present study will be helpful in the faunistic or taxonomic studies for strongylid nematodes related.

• Journal of Korean Neurosurgical Society
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• 제40권6호
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• pp.412-418
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• 2006

Objective : The safety of titanium metal cages in tuberculous spondylitis has not been investigated. We evaluated the outcome and complications of titanium mesh cages for reconstruction after thoracolumbar vertebrectomy in the tuberculous spondylitis. Methods : There were 17 patients with 18 operations on the tuberculous spondylitis in this study. Sixteen patients were operated with anterior corpectomy and reconstruction with titanium mesh cage followed by posterior transpedicular screw fixations on same day, two pateints were operated by either anterior or posterior approach only. After the affected vertebral body resection and pus drainage from the psoas muscle, titanium mesh cage, filled with morselized autogenous bone, was inserted. All the patients had antituberculosis medication for 18 months. The degree of kyphosis correction and the subsidence of cage were measured in the 15 patients available at a minimum of 2 years. Outcome was assessed with various cross-sectional outcome measures. Recurrent infection was identified by serial ESR[Erythrocyte Sedimentation Rate] and CRP[Cross Reactive Protein]. Results : There was no complication from the use of a titanium mesh cage. Recurrent infection was not detected in any case. Average preoperative of $9.2^{\circ}$ was reduced to $-2^{\circ}$ at immediate postoperative period, and on final follow up period kyphotic angle was measured to be $4.5^{\circ}$. Postoperatively, subsidence was detected in most patients especially at ambulation period, however further subsidence was prevented by the titanium mesh cage. Osseous union was identified in all cases at the final follow-up. Conclusion : The cylindrical mesh cage is a successful instrument in restoring and maintaining sagittal plane alignment without infection recurrence after vertebrectomy for tuberculous spondylitis.

• 한국정보과학회논문지:소프트웨어및응용
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• 제37권8호
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• pp.611-619
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• 2010

본 논문에서는 사용자가 실제와 같은 촉감을 느끼면서 가상 도자기의 물레 성형을 체험할 수 있는 E-Learning 시스템을 제안한다. 원통형으로 대칭을 이루는 도자기 모양의 특징에 착안하여 부채꼴 모양을 가진 요소의 집합으로 3차원 도자기를 모델링하였다. 부채꼴 요소법에 최적화된 충돌 처리와 인접요소간 상호작용 알고리즘을 고안하였으며, GPU 기반의 빠른 햅틱 모델과 시각 모델의 동기화를 구현하였다. 성능 평가 결과 부채꼴 요소법은 기존의 변형체 렌더링 기법에 비해 훨씬 더 조밀한 도자기 모델의 현실적인 실시간 햅틱 렌더링이 가능한 것을 확인하였다. 우리가 구현한 시스템을 도자기와 관련된 교육적인 컨텐츠와 잘 결합한다면 초등학생들을 대상으로 한 E-Learning 시스템으로 성공적인 활용이 가능할 것으로 예상된다.

• Smart Structures and Systems
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• 제14권3호
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• pp.479-499
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• 2014

This paper illustrates the damages of reinforced concrete and masonry minarets during October 23 (Erciş) and November 9 (Edremit), 2011 Van earthquakes in Turkey. Erciş and Edremit are townships located 90km and 18km from Van city center in Turkey, respectively. Ground accelerations and response spectrums for these earthquakes are given in this paper. A total of 63 reinforced concrete and masonry minarets are heavily damaged or collapsed in the city center and villages nearby after both earthquakes. Because of the fact that there is no Turkish standard and specification directly related to design of minarets, nearly all of the constructions are carried out by workers using only their own technical knowledge. So, all of the non-engineering reinforced concrete and masonry minarets completely collapsed or damaged heavily. From the study, it is seen that the damages are due to several reasons such as site effect, location, and length of the fault, reduction in cross section and formation of the discontinuity, use of plain reinforcement steel, use of concrete with insufficient strength, existence of short lap splices and incorrect end hook angle, larger mass and stiffness concentrations on some region, longitudinal reinforcements discontinuity, cracks at the cylindrical body, and damage of spire and end ornament. In addition to these reasons, the two earthquakes hit the minarets within seventeen days, causing progressive damage. So, the existing design and construction practices should be improved to provide sufficient earthquake performance. Also, it is recommended that there should be a safe distance between the minaret and surrounding structures to reduce the loose of life after earthquake.