• Journal of Ginseng Research
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• v.40 no.4
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• pp.334-343
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• 2016

Background: Progressed tissue culture techniques have allowed us to easily obtain mass products of tissue-cultured mountain ginseng over 100 yr old (TCMG-100). We investigated the effects of TCMG-100 extract on erectile function using in vitro and in vivo studies. Methods: To examine the relaxation effects and mechanisms of action of TCMG-100 on rabbit cavernosal strips evaluated in an organ bath. To investigate the long-term treatment effect of TCMG-100, 8-wk administration was performed. After administration of TCMG-100, intracavernosal pressure, cyclic guanosine monophosphate and nitric oxide (NO) levels of cavernosal tissue, serum testosterone level, histological observation of collagen fiber, endothelium, smooth muscle cell, and transforming growth factor-${\beta}1$ were investigated. Results: TCMG-100 extract displayed dose-dependent relaxation effects on precontracted rabbit corporal smooth muscle. The TCMG-100-induced relaxation was significantly reduced by removing the endothelium, and treatment with an NO synthase inhibitor or NO scavenger. Eight weeks of TCMG-100 administration increased intracavernosal pressure in a rat model. The levels of cyclic guanosine monophosphate and NO in the corpus callosum and serum testosterone level were also increased by TCMG-100 treatment. Furthermore, histological evaluation of collagen, smooth muscle, and endothelium showed increases in endothelium and smooth muscle, and a decrease in transforming growth factor-${\beta}1$ expression. Conclusion: These relaxation effects on corporal smooth muscle and increased erectile function suggest that TCMG-100 might be used as an alternative herbal medicine to improve erectile function.

• Geotechnical Engineering
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• v.14 no.1
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• pp.37-48
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• 1998

The effects of consolidation stress history including consolidation stress ratio, OCR and cyclic loading with drainage on the undrained shear strength of cohesive soil were investig toted. The ratio$(S_u/\sigma'_{vc})ckou/(S_U/\sigma_{vc})cuv$ was observed to increase with increasing OCR. The equation (1) in this paper by Mayne(1980) for the undrained shear strength of the overconsolidated clay and the equation (4) by Yasuhara(1994), for the postcyclic shear strength were found to be relatively well applicable in the case of Kofonsolidated. It was also suggested that the value of the critical state pore pressure parameter As in these two equations for the in situ shear strength of lightly overconsolidated clay(OCR< 3) be obtained by the standard consolidating test.

• Journal of the Korean Geotechnical Society
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• v.36 no.6
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• pp.35-46
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• 2020

The input parameters for numerical simulation of the liquefaction phenomenon need to be properly evaluated from laboratory and field tests, which are difficult to be performed in practical situations. In this study, the numerical simulation of the cyclic direct simple shear test was performed to analyze the applicability of Finn and PM4Sand models among the constitutive models for liquefaction simulation. The analysis results showed that the Finn model properly predicted the time when the excess pore water pressure reached the maximum, but failed to simulate the pore pressure response and the stress-strain behavior of post-liquefaction. On the other hand, the PM4Sand model properly simulated those behaviors of the post liquefaction. Finally, the evaluation procedure and the equations of the input parameters in the PM4Sand model were developed to mach the liquefaction cyclic resistance ratio corresponding to design conditions.

• Journal of Hydrogen and New Energy
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• v.13 no.1
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• pp.13-23
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• 2002

Hydrogenation properties of Mg-Ni and Mg-Ti-Ni alloys were investigated by Pressure-Composition Isotherm (PCI) test. Those alloys were fabricated by a new alloying method, Rotation-Cylinder Method (RCM). The as-cast microstructure of Mg-10 mass% Ni alloy consists of an island-like hydride forming $\alpha$-Mg phase and the eutectic structure. After 350 cyclic tests, Mg-lO mass % Ni alloy was pulverized into fine particles of 100 nm. The fine particles, which have a large specific surface area, are highly reactive with hydrogen. However, extreme pulvehzation can separate Mg from $Mg_2Ni$ in the eutectic structure, so $Mg_2Ni$ of the eutectic structure cannot behave as a dissociated hydrogen supplier.

• Mass Spectrometry Letters
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• v.3 no.2
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• pp.43-46
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• 2012

In this study, comprehensive two dimension gas chromatography (2D GC-MS) and 15 T Fourier transform ion cyclotron resonance mass spectrometry (15T FT-ICR MS) connected to atmospheric pressure photo ionization (APPI) have been combined to obtain detailed chemical composition of a diesel oil sample. With 2D GC-MS, compounds with aliphatic alkyl, saturated cyclic ring(s), and one aromatic ring structures were mainly identified. Sensitivity toward aromatic compounds with more than two aromatic rings was low with 2D GC-MS. In contrast, aromatic compounds containing up to four benzene rings were identified by APPI FT-ICR MS. Relatively smaller abundance of cyclic ring compounds were found but no aliphatic alkyl compounds were observed by APPI FT-ICR MS. The data presented in this study clearly shows that 2D GC-MS and 15T FT-ICR MS provides different aspect of an oil sample and hence they have to be considered as complementary techniques to each other for more complete understanding of oil samples.

• Coupled systems mechanics
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• v.2 no.4
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• pp.375-387
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• 2013

Soils consist of an assemblage of particles with different sizes and shapes which form a skeleton whose voids are filled with water and air. Hence, soil behaviour must be analyzed by incorporating the effects of the transient flow of the pore-fluid through the voids, and therefore requires a two-phase continuum formulation for saturated porous media. The present paper presents briefly the Biot's basic theory of dynamics of saturated porous media with u-P formulation to determine the responses of pore fluid and soil skeleton during cyclic loading. Kelvin elements are attached to transmitting boundary. The Pastor-Zienkiewicz-Chan model has been used to describe the inelastic behavior of soils under isotropic cyclic loadings. Newmark-Beta method is employed to discretize the time domain. The response of fluid-saturated porous media which are subjected to time dependent loads has been simulated numerically to predict the liquefaction potential of a semi-infinite saturated sandy layer using finite-infinite elements. A settlement of 17.1 cm is observed at top surface. It is also noticed that liquefaction occurs at shallow depth. The mathematical advantage of the coupled finite element analysis is that the excess pore pressure and displacement can be evaluated simultaneously without using any empirical relationship.

• Geomechanics and Engineering
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• v.4 no.4
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• pp.251-262
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• 2012

Triaxial tests are essential to estimate the shear strength properties of the soil or rock. Normally triaxial tests are carried out on samples of 38 mm diameter and 76 mm height. Granular materials, predominantly used in base/sub-base construction of pavements or in railways have size range of 60-75 mm. Determination of shear strength parameters of those materials can be made possible only through triaxial tests on large diameter samples. This paper describes a large diameter cyclic triaxial testing facility set up in the Geotechnical Engineering lab of Indian Institute of Science. This setup consists of 100 kN capacity dynamic loading frame, which facilitates testing of samples of up to 300 mm diameter and 600 mm height. The loading ram can be actuated up to a maximum frequency of 10 Hz, with maximum amplitude of 100 mm. The setup is capable of carrying out static as well as dynamic triaxial tests under isotropic, anisotropic conditions with a maximum confining pressure of 1 MPa. Working with this setup is a difficult task because of the size of the sample. In this paper, a detailed discussion on the various problems encountered during the initial testing using the equipment, the ideas and solutions adopted to solve them are presented. Pilot experiments on granular sub-base material of 53 mm down size are also presented.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.258-265
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• 2001

Turbine blade is subject to force of three type ; torsional force by torsion-mount, centrifugal force by rotation of rotor and cyclic bending force by steam pressure. Cyclic bending force of them is main factor on fatigue fracture. In the X-ray diffraction method, the change in the values related to plastic deformation and residual stress near the fracture surface mat be determined, and information of internal structure of material can be obtained. Therefore, to find a fracture mechanism of torsion-mounted blade in nuclear plant, based on the information from the fracture surface obtained by fatigue test, the correlation of X-ray parameter and fracture mechanics parameter was determined, and then the load applied to actual broken turbine blade parts was predicted. Failure analysis is performed by finite element method and Goodman diagram on torsion-mounted blade.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.8
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• pp.1295-1302
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• 2003

In order to evaluate a failure behavior of pipe with notch-type wall thinning, the present study performed full-scale pipe tests using the 102mm, Schedule 80 pipe specimen simulated notch- and circular-type thinning defects. The pipe tests were conducted under the conditions of both monotonic and cyclic bending moment at a constant internal pressure of 10 MPa. From the results. of experiment the failure mode, load carrying capacity, deformation ability, and fatigue life of a notch-type wall thinned pipe were investigated, and they were compared with those of a circular-type wall thinned pipe. The failure mode of notched pipe was similar to that of circular-type thinned pipe under the monotonic bending load. Under the cyclic bending load, however, the mode was clearly distinguished with variation in the shape of wall thinning. The load carrying capacity of a pipe containing notch-type wall thinning was about the same or slightly lower than that of a pipe containing circular-type wall thinning when the thinning area was subjected to tensile stress, whereas it was higher than that of a pipe containing circular-type thinning defect when the thinning area was subjected to compressive stress. On the other hand, the deformation ability and fatigue life of a notch-type wall thinned pipe was lower than those of a circular-type wall thinned pipe.

• Structural Engineering and Mechanics
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• v.39 no.4
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• pp.499-520
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• 2011

The effectiveness of a technique for the repair of reinforced concrete members in combination with a technique for the repair of masonry walls of infilled frames, damaged due to cyclic loading, is experimentally investigated. Three single - story, one - bay, 1/3 - scale frame specimens are tested under cyclic horizontal loading, up to a drift level of 4%. One bare frame and two infilled frames with weak and strong infills, respectively, have been tasted. Specimens have spirals as shear reinforcement. The applied repair technique is mainly based on the use of thin epoxy resin infused under pressure into the crack system of the damaged RC joint bodies, the use of a polymer modified cement mortar with or without a fiberglass reinforcing mesh for the damaged infill masonry walls and the use of CFRP plates to the surfaces of the damaged structural RC members, as external reinforcement. Specimens after repair, were retested in the same way. Conclusions concerning the effectiveness of the applied repair technique, based on maximum cycles load, loading stiffness, and hysteretic energy absorption capabilities of the tested specimens, are drawn and commented upon.