• 한국축산식품학회지
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• 제34권4호
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• pp.482-495
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• 2014

The objectives of this study were to know the effect of repeated freeze-thaw cycles of beef on the sensory, physicochemical quality and microbiological assessment. The effects of three successive freeze-thaw cycles on beef forelimb were investigated comparing with unfrozen fresh beef for 75 d by keeping at $-20{\pm}1^{\circ}C$. The freeze-thaw cycles were subjected to three thawing methods and carried out to know the best one. As the number of freeze-thaw cycles increased color and odor declined significantly before cook within the cycles and tenderness, overall acceptability also declined among the cycles after cook by thawing methods. The thawing loss increased and dripping loss decreased significantly (p<0.05). Water holding capacity (WHC) increased (p<0.05) until two cycles and then decreased. Cooking loss increased in cycle 1 and 3, but decreased in cycle 2. pH decreased significantly (p<0.05) among the cycles. Moreover, drip loss, cooking loss and WHC were affected (p<0.05) by thawing methods within the cycles. 2-Thiobarbituric acid (TBARS) value increased (p<0.05) gradually within the cycles and among the cycles by thawing methods. Total viable bacteria, total coliform and total yeast-mould count decreased significantly (p<0.05) within and among the cycles in comparison to the initial count in repeated freeze-thaw cycles. As a result, repeated freeze-thaw cycles affected the sensory, physicochemical and microbiological quality of beef, causing the deterioration of beef quality, but improved the microbiological quality. Although repeated freeze-thaw cycles did not affect much on beef quality and safety but it may be concluded that repeated freeze and thaw should be minimized in terms of beef color for commercial value and WHC and tenderness/juiciness for eating quality.

• 대한임상검사과학회지
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• 제36권1호
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• pp.33-37
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• 2004

In order to study the effect of temperature of denaturation, annealing and extension and cycles on amplification of DNA by PCR method, We isolated the hepatitis B virus DNA from hepatitis B patient blood and compared the density of DNA amplified by Reference PCR Program (denaturation at $94^{\circ}C$ for 30 sec., annealing at $60^{\circ}C$ for 1 min., extension at $72^{\circ}C$ for 1 min., holding at $72^{\circ}C$ for 5min., 30 cycles) that is usually used in laboratory to the density of DNA amplified by PCR program changed only the denaturation temperature or annealing temperature or extension temperature. We amplified about 341bp of hepatitis B virus DNA by Reference PCR Program from hepatitis patient blood, but the DNAs denatured at $72^{\circ}C$ or $60^{\circ}C$ were not detectable on photoradiography film. The DNA amplified at $37^{\circ}C$ of annealing temperature was not detectable, but the DNA annealed at $72^{\circ}C$ was detectable the lower density of DNA than the DNA amplified by Reference PCR Program. Each DNA amplified by PCR program changed only the extension temperature to $37^{\circ}C$ or $60^{\circ}C$ was almost same density as DNA amplified by Reference PCR Program. We compared the density of hepatitis B virus DNA amplified by Reference PCR Program for 30 cycles, 20 cycles, 10 cycles, and 5 cycles. The DNA cycled for 20 cycles was not amplified well as cycled for 30 cycles, but the DNA was detectable on the photoradiography film. The DNAs amplified for 10 cycles or 5 cycles were not detectable on photoradiorgaphy film. The concentration of hepatitis B virus DNA amplified in Reference PCR condition for 30 cycles, 20 cycles, 10 cycles, and 5 cycles were $72{\mu}g/m{\ell}$, $83{\times}10^{-3}{\mu}g/m{\ell}$, $27{\times}10^{-6}{\mu}g/m{\ell}$, and nondetectable, respectively.

• Asian-Australasian Journal of Animal Sciences
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• 제5권3호
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• pp.583-585
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• 1992

A study was undertaken to determine the incidence of short oestrus cycles and associated serum progesterone levels in Nili-Ravi buffaloes. Forty lactating buffaloes were kept under observation for oestrus activity for a period of sixty days. Blood samples from jugular vein from twenty buffaloes were used to determine associated serum progesterone levels during short oestrus cycles. Incidence of short oestrus cycles was 15.5 percent (Nine out of fifty eight oestrus cycles) and most of the short oestrus cycles occurred between first and second oestrus after calving. Lengths of short oestrus cycles ranged from 6 to 14 days. The most frequent length was 11 days. Serum progesterone levels were lower at oestrus and increased gradually attaining peak levels of 1.3 and 1.8 ng/ml on 7th day of 9 and 11 day short oestrus cycles. One buffalos exhibiting a short oestrus cycle of 12 days conceived which indicated that ovulation took place at the oestrus of short cycle.

• 한국환경보건학회지
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• 제49권3호
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• pp.159-168
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• 2023

Background: An ongoing environmental exposure assessment of humidifier disinfectants (HDs) has been conducted since November 2011 among individuals who experienced HD exposure-related adverse health effects. It is being performed in order to determine and quantify exposure to humidifier disinfectants in victims and their families. To date, the assessment has encompassed Cycles I-to-V. There is no report summarizing the characteristics of the subjects from the overall cycles. Objectives: We intended to examine the individual characteristics related to demographics, HD usage, and HD exposure using integrated data from Cycles I-to-V of the environmental exposure assessment of HDs and the changes with the cycles. Methods: We included 7,543 individuals who participated in Cycles I-to-V of the environmental exposure assessment of HDs. We summarized the participants' characteristics regarding their demographics (e.g., sex, education level, and age), HD usage history (e.g., product name, ingredient, and frequency of HD use), and HD exposure (e.g., daily time of HD use, cumulative time of HD use, and exposure intensity). In addition, their characteristics were compared across the cycles of the exposure assessment. Results: Among the 7,543 participants from Cycles I-to-V, there were more male participants than females (51.05% overall), except for Cycles I and III. Across all cycles, a higher proportion of survivors was observed than deceased individuals. While PHMG was the most prevalent ingredient in HDs throughout all the cycles, its proportion gradually decreased over the course of the examination cycles. Participants in Cycle I reported longer daily times of HD use compared to those in the subsequent cycles. On the other hand, cumulative time of HD use was shorter in the earlier cycles than in the later cycles. Conclusions: Using the integrated data from the full cycles of the environmental exposure assessment, this study identified changes in demographic characteristics as well as the HD exposure characteristics between the participants across different cycles.

• 천문학회지
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• 제48권6호
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• pp.325-331
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• 2015

We study an association between the duration of solar activity and characteristics of the latitude distribution of sunspots by means of center-of-latitude (COL) of sunspots observed during the period from 1878 to 2008 spanning solar cycles 12 to 23. We first calculate COL by taking the area-weighted mean latitude of sunspots for each calendar month to determine the latitudinal distribution of COL of sunspots appearing in the long and short cycles separately. The data set for the long solar cycles consists of the solar cycles 12, 13, 14, 20, and 23. The short solar cycles include the solar cycles 15, 16, 17, 18, 19, 21, and 22. We then fit a double Gaussian function to compare properties of the latitudinal distribution resulting from the two data sets. Our main findings are as follows: (1) The main component of the double Gaussian function does not show any significant change in the central position and in the full-width-at-half-maximum (FWHM), except in the amplitude. They are all centered at ~ 11° with FWHM of ~ 5°. (2) The secondary component of the double Gaussian function at higher latitudes seems to differ in that even though their width remains fixed at ~ 4°, their central position peaks at ~ 22.1° for the short cycles and at ~ 20.7° for the long cycles with quite small errors. (3) No significant correlation could be established between the duration of an individual cycle and the parameters of the double Gaussian. Finally, we conclude by briefly discussing the implications of these findings on the issue of the cycle 4 concerning a lost cycle.

• 한국통신학회논문지
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• 제33권2C호
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• pp.173-177
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• 2008

본 논문에서, 우리는 다수의 짧은 주기들을 추가함으서 LDPC 부호의 성능을 향상시킨다. 짧은 주기, 특히 길이가 4인 주기는 만약 표준 BP 복호가 쓰인다면 LDPC 부호의 성능을 저하시킨다. 그래서 현재의 연구들은 성능 높은 LDPC 부호를 설계하기 위하여 길이가 4인 주기들을 없애는데 초점을 맞추고 있다. 우리는 만약 수정된 BP 복호를 사용하면 다수의 길이가 4인 주기들은 LDPC 부호의 성능을 향상 시키는 것을 발견했다. 본 논문에서는 다수의 짧은 주기들을 가진 LDPC 부호를 위한 수정된 BP 복호 알고리즘이 소개되고 또한 다수의 짧은 주기들을 가지는 LDPC 부호의 수정된 BP 복호성능이 짧은 주기를 가지지 않는 LDPC 부호의 표준 BP 복호 성능보다 우수함을 보였다.

• 한국의류학회지
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• 제23권5호
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• pp.745-756
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• 1999

The purpose of this study is to investigate the characteristics of the clothing consumption expenditures by the business cycles in Korea during the period of first quarter of 1979 to second quarter of 1998. Business cycles were examined using data GNP from the National Accounts published by the Bank of Korea and clothing expenditures from the monthly statistics of Korea published by the National Statistical Office of Korea. Data were analyzed by regression analysis standard deviation sample cross-correlation coefficient and skewness statistics. The main results are as follows. 1. During the period of 1979.I-1998.II GNP and per-person consumption expenditures for clothing and shoes have continuously increased except during 1980 and the recent depression of the national economy. Clothing expenditures dropped severely during the two recent depression of the national economy. Clothing expenditure dropped severely during the two depression periods. Clothing expenditures were the highest in the fourth quarter and the lowest in the third quarter of the year. 2. According to the results of the regression analysis the business cycles had a significant influence on the clothing expenditures. the volatility of the clothing expenditure was 2.60 times higher than that of the business cycles. 3. Clothing expenditures displayed procyclical fluctuation and coincident movement to the business cycles. Also clothing expenditures showed an unsymmetric behavior over the expansion phases and contraction phases of the business cycles. That is the clothing expenditures increased slowly in the expansion phases and decreased quickly and severely in the contraction phases of the business cycles.

• Journal of Gastric Cancer
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• 제22권2호
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• pp.107-119
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• 2022

Purpose: We aimed to explore whether the prognosis of patients treated with capecitabine and oxaliplatin (XELOX) or S-1 and oxaliplatin (SOX) regimens who received fewer cycles of chemotherapy after D2 radical resection for gastric cancer (GC) would be non-inferior to that of patients who received the standard number of cycles of chemotherapy. Materials and Methods: Data on patients who received XELOX or SOX chemotherapy after undergoing D2 radical resection at Harbin Medical University Cancer Hospital between January 2011 and May 2016 were collected. Results: In patients who received 4, 6, and 8 cycles of chemotherapy, the 5-year overall survival (OS) rates were 59.4%, 64.8%, and 62.7%, respectively. Compared to patients who received 4 cycles of chemotherapy, those who received 6 cycles (hazard ratio [HR], 0.882; 95% confidence interval [CI], 0.599-1.299; P=0.52) or 8 cycles (HR, 0.882; 95% CI, 0.533-1.458; P=0.62) of chemotherapy did not exhibit significantly prolonged OS. The 3-year disease-free survival (DFS) rate of patients who received 4, 6, and 8 cycles of chemotherapy was 62.1%, 67.2%, and 60.8%, respectively. Compared to patients who received 4 cycles of chemotherapy, those who received 6 cycles (HR, 0.835; 95% CI, 0.572-1.221; P=0.35) or 8 cycles (HR, 0.972; 95% CI, 0.606-1.558; P=0.91) of chemotherapy did not show significantly prolonged DFS. However, the 3-year DFS and 5-year OS rates of patients who received 6 cycles of chemotherapy appeared to be superior to those of patients who received 4 and 8 cycles of chemotherapy. Conclusions: For patients with stage III GC, 4 to 6 cycles of XELOX or SOX chemotherapy may be a favorable option. This study provides a rationale for further randomized clinical trials.

• Animal Bioscience
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• 제34권8호
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• pp.1375-1381
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• 2021

Objective: This study was conducted to determine the effect of freeze-thawed cycles (Fresh meat, F-T 1 cycle and F-T 2 cycles) on the quality characteristics of porcine longissimus dorsi muscle. Methods: A total of 20 three-crossbred pigs (Duroc×[Large White×Landrace]) were randomly obtained from a commercial slaughterhouse in Thailand. Muscle samples were immediately taken from 10 to 11th of the longissimus dorsi for histochemical analysis. The muscles were cut into 2.54 cm-thick chops. A minimum of 20 chops were used for each treatment (fresh meat, freeze-thawed 1 and 2 cycles). Individually chops were packaged in polyethylene bags and frozen at -20℃ for 6 months followed by thawing in refrigerator at 4℃ for 24 h (the 1st freeze-thawed cycle). The freeze-thawed procedure was repeated for two cycles (the 2nd freeze-thawed cycle). Thawing loss, shear force value, citrate synthase activity and muscle fiber characteristics were determined on the muscles. Results: Results showed that increasing of freeze-thawed cycle increased the thawing loss (p<0.01) and citrate synthase activity (p<0.001). Shear force value of fresh meat was higher than freeze-thawed 1 and 2 cycles (F-T 1 cycle and F-T 2 cycles). Freeze-thawed cycles affected muscle characteristics. Muscle fiber area and muscle fiber diameter decreased with an increasing number of freeze-thawed cycles (p<0.001), while the thickness of endomysium and perimysium were increased (p<0.001). Conclusion: Repeated freeze-thawed cycles degraded muscle fiber structure and deteriorated pork quality.

• 동력기계공학회지
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• 제21권1호
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• pp.24-29
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• 2017

Studies in liquid-vapor ejector, which performs a great efficiency in refrigeration cycle is highly concerned. This paper is based on basic refrigeration cycle and three ejector refrigeration cycles and the comparison and contrasts about when 6 different refrigerants are applied to such refrigeration cycles. All cycles had a percentage increase of COP from 4 to 74% when ejector was applied, and the source of increasement was the decrease of total work done due to ejector's pressure recovery function. When R-245fa is applied to cycle (d), results showed that COP was the most superior in such cycle, R-245fa showed high volume entrainment ratio in all cycles. Future studies in refrigeration cycles will require more knowledge and experiments on ejector's appliance to refrigeration cycles and the actuation of such functions.