• Korean Business Review
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• v.11
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• pp.15-38
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• 1998

This study explores the evolution of technical innovation over time. It focuses on sectors of the information technology because this industry can be referred to as one of the most dynamic industries of all times. Following evolutionary theorists, we argue that technological change is gradual and that superior firms and technologies are reward by the' selection' environment. In the initial phase of the industry life cycle, technological change is expected to be radical and uncertainty is high. Over time a product or technology is likely to arise which stands out above all other products or technologies. These so-called 'basic designs' serve as sorts of 'technological guideposts' for further developments in the technology. Once a basic design established, technological progress tends to follow consistent paths or trajectories. The cumulative character of technological progress facilitates a rapid expansion of the boundaries of the technology until the natural limits of the technology are approached and technological progress slows down. Following ecological theories, supply-side developments in the industry are described on the basis of five different organizational types. On the basis of this pattern of market and technological evolution we came up with seven basic propositions.

• Journal of Korean Academy of Nursing
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• v.24 no.3
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• pp.432-447
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• 1994

Koreans are one of the fastest growing immigrant groups in America. Adjsting to life in foreign country produces a great deal of stress. Differences in culture, language, expectation and social behavior can lead to misunderstandings. The pregnancy and delivery event is one of maturational crisis in life cycle. The purpose of this research was to understand the structure of the lived experience of pregnant women and postpartum mothers who had immigrated to the United States. The research question was "What is the structure of the experience of pregnant women and postpartal mothers?" The sample consisted of 16 women registrated at the Obstetrics and Gynecology Department of one local clinic in Hawaii. The unstructured interviews were carried out from Jnuary 5, through January, 30, 1994. They were audio-recorded and analyzed using Van Kaam's method. There are different views on the causative factors of stress. Maladjustement to the immigrant life, spousal conflicts, anxiety related to bringing up the bay and conflicts between mother-in-law and daughter-in-law are considered to be related factors. The experiences of pregnant women over the period of the pregnancy can be varied and can include change of body image, emotional and physical change. The experiences of postpartum mothers over the postpartum period can be varied and can include postpartum depression emotional irritability, fear related to bringing up the baby and disappointment with husband. Positive experiences over the period of pregnancy and postpartum were the strengthen-ing beliefs. Sources of support were, first, spouse then mother and faith. Support was also received from the physician in charge and through self-control. The nurse, by providing empathetic support, should be a person with whom they can express their feelings and share their experiences.

• Journal of Soil and Groundwater Environment
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• v.20 no.3
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• pp.34-40
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• 2015

Studies using stable water vapor isotopes have been recently conducted over the past two decades because of difficulties in analysis and sample collection in the past. Stable water vapor isotope data provide information of the moisture transport from ocean to continent, which are also used to validate an isotope enabled general circulation model for paleoclimate reconstructions. The isotopic compositions of groundwater and water vapor also provide a clue to how moisture moves from soil to atmosphere by evapotranspiration. International Atomic Energy Agency designates the stations over the world to observe the water vapor isotopes. To analyze the water vapor isotopes, a cryogenic sampling method has been used over the past two decades. Recently, two types of laser-based spectroscopy have been developed and remotely sensed data from satellites have the global coverage. In this review, measurements of isotopic compositions of water vapor will be introduced and some studies using the water vapor isotopes will also be introduced. Finally, we will suggest the future study in Korea.

• International Journal of Highway Engineering
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• v.17 no.4
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• pp.77-87
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• 2015

PURPOSES: It is theoretically well known all over the world, that porous hot mixed asphalt (HMA) with hydrated Lime improves moisture and rutting resistance, and reduces pothole occurrence frequency, as well as the life cycle cost (LCC). METHODS : Addictive in the two different formations of the liquid anti-stripping Agent and powder Hydrated-Lime was applied in this investigation in order to obtain relatively clear results according to their types and conditions. Firstly, the moisture conditions were set, and applied to the porous HMA mixtures with hydrated lime (anti-stripping agent). Next, it was followed by a non-destructive test with the application of three freeze-thaw cycles, which were individually carried out thrice to compare the results of the dynamic moduli. Lastly, the hydrated lime effect related to moisture sensibility to porous HMA has been verified through the analysis of the modulus results regarding the change rate of dynamic modulus per n-cycle. RESULTS: It is clear from this investigation, that the dynamic modulus is inversely proportional to the change in temperature, as the graph representing the rigidity of the thermorheologically simple (TRS) material showed gradual decline of the dynamic modulus with the increase in temperature. CONCLUSIONS: The porous HMA mixture with the anti-stripping agent (hydrated Lime) has been found to be more moisture resistant to freezing and thawing than the normal porous HMA mixture. It is clear that the hydrated lime helps the HMA mixture to improve its fatigue resistance.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.215-224
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• 2022

This study tried to examine the effect of cost asymmetry on food service companies and what characteristics affect such cost behavior. This study analyses cost behavior for cost of good sold, selling, general and administrative cost over the 2019-2020 period. Also, the rate of change in activity level was measured using change in sales. This study measures the behavior of cost using the research model of [1]. As a result of the analysis, it was found that food service companies exhibited cost asymmetric behavior as their sales level decreased. In addition, the cost asymmetric behavior has been strengthened since the corona virus, and the shorter the operating cycle. Lastly, the shorter the inventory holding period and the collection period of accounts receivable, which are components of the operating cycle, more strengthen asymmetric behavior of costs. These results seem to be meaningful in examining the cost structure and factors that may affect the structure for food service industry. This has approached the cost aspect of the situation faced by service food companies due to COVID-19, and it can be suggested that this pandemic can lead to cost reduction due to a decrease in corporate sales.

• Biomedical Science Letters
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• v.15 no.1
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• pp.97-99
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• 2009

Geldanamycin is a benzoquinone ansamycin antibiotic that binds to cytosol HSP90 (Heat Shock Protein 90) and changes its biological function. HSP90 is involved in the intracellular important roles for the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis. To identify genes expressed during geldanamycin treatment against neurons of rats (PC12 cells), DNA microarray method was used. We have isolated 2 gene groups (up-or down-regulated genes) which are geldanamycin differentially expressed in neurons. Granzyme B is the gene most significantly increased among 204 up-regulated genes (more than 2 fold over-expression) and Chemokine (C-C motif) ligand 20 is the gene most dramatically decreased among 491 down-regulated genes (more than 2 fold down-expression). The gene increased expression of Cxc110, Cyp11a1, Gadd45a, Gja1, Gpx2, Ifua4, Inpp5e, Sox4, and Stip1 are involved stress-response gene, and Cryab, Dnaja1, Hspa1a, Hspa8, Hspca, Hspcb, Hspd1, Hspd1, and Hsph1 are strongly associated with protein folding. Cell cycle associated genes (Bc13, Brca2, Ccnf, Cdk2, Ddit3, Dusp6, E2f1, Illa, and Junb) and inflammatory response associated genes (Cc12, Cc120, Cxc12, Il23a, Nos2, Nppb, Tgfb1, Tlr2, and Tnt) are down-regulated more than 2 times by geldanamycin treatment. We found that geldanamycin is related to expression of many genes associated with stress response, protein folding, cell cycle, and inflammation by DNA microarray analysis. Further experimental molecular studies will be needed to figure out the exact biological function of various genes described above and the physiological change of neuronal cells by geldanamycin. The resulting data will give the one of the good clues for understanding of geldanamycin under molecular level in the neurons.

• Korean Journal of Environment and Ecology
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• v.32 no.6
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• pp.582-590
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• 2018

Although there are many studies of the effect of climate change on the breeding phenology and community diversity of amphibians, the studies of variations in reproductive population size of individual species according to climate change are still lacking. We examined the effect of climate change on the reproductive population size of Rana huanrenensis and Hynobius leechii, which bred in mountain valleys, by surveying the reproductive population of the two species between 2005 and 2012 and analyzing the correlation between the variation of the outdoor population and the surrounding climate change factors, obtained from a meteorological observatory located at 5.6 km from the study site. The size of the reproductive population of the two species commonly fluctuated with aan pproximately 3.5-year cycle. That of H. leechii, in particular, decreased significantly over eight years. The air temperature tended to more closely relate with the reproductive population size of R. huanrenensis as was the case of the precipitation with that of H. leechii. The yearly mean highest temperature and spring mean temperature variation consistently decreased over the eight years, and the latter was related with the significantly decreased size of H. leechii reproductive population. These results showed that recent climate change directly could affect the reproductive population size of amphibians, particularly H. leechii, which breeds in mountain valleys.

• Korean Journal of Remote Sensing
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• v.27 no.1
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• pp.17-24
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• 2011

Global warming and climatic changes due to human activities impact on marine and terrestrial ecosystems, which feedbacks to climate system. These negative feedbacks amplify or accelerate again global climate change. In particular, it is important to analyze vegetation change. This study attempts to analyze quantitatively vegetation change in Korea peninsula by using harmonic analysis. Harmonic-Analysis based on Fourier Transform is the method to effectively demonstrate for time series data. Especially, Harmonic-Analysis is very suitable method to analyze vegetation change because the vegetation repeats the cycle growth and extinction every year. The result of harmonic-analysis shows vegetation change as time passes. In this study, SPOTNEGETATION S10 MVC NDVI data was used during last 10 years (1999-2008) in Korea Peninsula. Also, land type classification used MODIS Land Cover Map data. The study estimated that phase values moved up approximately 0.5 day per year in cropland and 0.8 day per year in forest.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.273-273
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• 2002

Masan barber was situated in S.Korean southern central coast. And it is contributing greatly in S.korea's economy development to international trading port of Heaven's blessing that possess natural, geographical situation. Also, because there are Masan free tax area and chanwon heavy industrial complex, sachon air industrial complex etc. on back, it is important permanency in our country. Specially, because inland transport routes such as southern highway, Guma highway and national road system are developed well, the importance is very high. Masan harbor 1899.05.01 be that opened, the 1st and 2nd (central pier) was build 1938∼1944 year, and the 3rd pier was 1973∼1978 year. the 4th pier was 1974∼1983 year, 5th pier was 1984∼1988, 6th pier (west pier) was 1985∼1992 year. it was developed over 100 years. But, it did great many harbor and bay development of last 100 yens but research about coastline change and seashore reclamation is insufficient. Therefore, this research executed research about coastline change of Masan bay of last 100 years, In this study, we analyzed aerial photographs and tide data for the past 100 years using digital aerial photo analysis and GIS techniques for each 3-year interval. We abstracted beach DEM (digital elevation model) and ortho aerial photographs, and conducted a space analysis. As a result, we were able to identify changes in the area As a result, we drew 10 years cycle coastline change of Masan bay. and we can detect bay coastal line change and calculate refill rate.

• The Korean Journal of Pharmacology
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• v.20 no.2
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• pp.35-47
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• 1984

Contents of immunoreactive ${\beta}-endorphin$ and maximum of $^3H-morphine$ binding was measured in the rat midbrain homogenates from different subgroups at 24 hour interval over 24 hours. Animals were adapted to the light-dark cycle(L : D, 12: 12) or constant darkness (D : D, 12 : 12) for 3 weeks. After the adaptation, 0.5ml of physiologic saline or drug was administered twice a day for 2 weeks. A highly significant circadian rhythm with the peak$(94.8{\pm}7.7\;fmole/mg\;protein)$ at 06:00 and the nadir $(27.6{\pm}2.4\;fmole/mg\;protein)$ at 18:00 was observed in constant of group. Constant dark or treatment of reserpine, pargyline, imipramine, amphetamine and chlorpromazine modified the diurnal rhythm in the time of peak and nadir, shape, phase amplitude and 24 hour mean of ${\beta}-endorphin$ contents. Opiate receptor binding by $^3H-morphine$ also showed highly significant diurnal change in control and constant dark adapted rats. Statistical analysis by one-way analysis of variance and two-way analysis of variance indicates that the·re are highly significant differences between the diurnal change of ${\beta}-endorphin$ in control and those constant dark adapted and drug treated groups. However diurnal change of Maximum $^3H-morphine$ binding is closely related to the change of ${\beta}-endorphin$ contents. The results are interpreted with regard to the circadian rhythm of beta-endorphin contents, its modification by psychoactive drugs and possible mechanism of diurnal change of opiate receptor in brain.