• Title/Summary/Keyword: Cx32

Search Result 32, Processing Time 0.032 seconds

Distances of Type II-P Supernovae SN 2014cx and SN 2017eaw

  • Kim, Sophia;Im, Myungshin;Choi, Changsu
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.43 no.1
    • /
    • pp.31.3-32
    • /
    • 2018
  • Supernovae (SNe) are well known as good cosmological distance probes owing to their brightness. Specifically, type Ia SNe contribute greatly to our understanding of acceleration of cosmic expansion. However, type IIP supernovae are the most common type of SNe and have been found out to a large redshift, so the application of these SNe as distance indicators is promising. IMSNG is a project for monitoring nearby galaxies (<50Mpc) to catch early light curves of transients and get inspections of their progenitors. The daily monitoring observation allows us to construct a dense light curve of SNe, too. In this talk, we present the light curves of two SNe IIP, SN 2014cx (NGC337) and SN 2017eaw (NGC6946), using our IMSNG data. A newly developed technique, the Photometric Color Method (PCM), employs only photometric data to estimate distances for SNe IIP. We present the distances to our targets measured through PCM and compare this to that of obtained via other methods.

  • PDF

Effect of Amino Terminus of Gap Junction Hemichannel on Its Channel Gating (간극결합채널의 아미노말단이 채널개폐에 미치는 영향)

  • Yim Jaegil;Cheon Misaek;Jung Jin;Oh Seunghoon
    • Journal of Life Science
    • /
    • v.16 no.1
    • /
    • pp.37-43
    • /
    • 2006
  • Gap junction is an ion channel forming between adjacent cells. It also acts as a membrane channel like sodium or potassium channels in a single cell. The amino acid residues up to the $10^{th}$ position in the amino (N)-terminus of gap junction hemichannel affect gating polarity as well as current-voltage (I-V) relation. While wild-type Cx32 channel shows negative gating polarity and inwardly rectifying I-V relation, T8D channel in which threonine residue at $8^{th}$ position is replaced with negatively charged aspartate residue shows reverse gating polarity and linear I-V relation. It is still unclear whether these changes are resulted from the charge effect or the conformational change of the N-terminus. To clarify this issue, we made a mutant channel harboring cysteine residue at the $8^{th}$ position (T8C) and characterized its biophysical properties using substituted-cysteine accessibility method (SCAM). T8C channel shows negative gating polarity and inwardly rectifying I-V relation as wild-type channel does. This result indicates that the substitution of cysteine residue dose not perturb the original conformation of wild-type channel. To elucidate the charge effect two types of methaenthiosulfonate (MTS) reagents (negatively charged $MTSES^-$ and positively charged $MTSET^+$) were used. When $MTSES^-$ was applied, T8C channel behaved as T8D channel, showing positive gating polarity and linear I-V relation. This result indicates that the addition of a negative charge changes the biophysical properties of T8C channel. However, positively charged $MTSET^+$ maintained the main features of T8C channel as expected. It is likely that the addition of a charge by small MTS reagents does not distort the conformation of the N-terminus. Therefore, the opposite effects of $MTSES^-$ and $MTSETT^+$ on T8C channel suggest that the addition of a charge itself rather than the conformational change of the N-terminus changes gating polarity and I-V relation. Furthermore, the accessibility of MTS reagents to amino acid residues at the $8^{th}$ position supports the idea that the N-terminus of gap junction channel forms or lies in the aqueous pore.

Evaluation of Image Quality for Compressed SENSE(CS) Method in Cerebrovascular MRI: Comparison with SENSE Method (뇌혈관자기공영영상에서 Compressed SENSE(CS) 기법에 대한 영상의 질 평가: SENSE 기법과 비교)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
    • /
    • v.15 no.7
    • /
    • pp.999-1005
    • /
    • 2021
  • The object of this research is CS, which increases resolution while shortening inspection time, is applied to MRA to compare the quality of images for SENSE and CS techniques and to evaluate SNR and CNR to find out the optimal techniques and to provide them as clinical basic data based on this information. Data were analyzed on 32 patients who performed TOF MRA tests at a university hospital in Chung cheong-do (15 males, 17 females), ICA stenosis:10, M1 Aneurysm:10, and average age 53 ± 4.15). In the inspection, the inspection equipment was Ingenia CX 3.0T, Archieva 3.0T, and 32 channel head coil and 3D gradient echo as a method for equipment data. SNR and CNR of each image were measured by quantitative analysis, and the quality of the image was evaluated by dividing the observer's observation into 5 grades for qualitative evaluation. Imaging evaluation is described as being significant when the p-value is 0.05 or less when the paired T-test and Wilcoxon test are performed. Quantitative analysis of SNR and CNR in TOF MRA images Compared to the SENSE method, the CS method is a method measurement method (p <0.05). As an observer's evaluation, the sharpness of blood vessels: CS (4.45 ± 0.41), overall image quality: CS (4.77 ± 0.18), background suppression of images: CS (4.57 ± 0.18) all resulted in high CS technique (p = 0.000). In conclusion, the Compressed SENSE TOF MRA technique shows superior results when comparing and evaluating the SENSE and Compressed SENSE techniques in increased flow rate magnetic resonance angiography. The results are thought to be the clinical basis material in the 3D TOF MRA examination for brain disease.

Illuminating Characteristics of an Incandescent Lamp (전조용 백열등의 조도 특성)

  • 김태한;이경진;이정택
    • Journal of Biosystems Engineering
    • /
    • v.25 no.1
    • /
    • pp.25-32
    • /
    • 2000
  • Motivated by the need for developing the more efficient lighting system for light culture in the greenhouses, this paper aims to predict the illumination of incandescent lamp according to various levels of lighting and various kinds of the lamp. The results obtained in this experiment are summarized as follows. 1. The general equation to predict the illumination according to the kind of incandescent lamp and the installation height was suggested as {{{{y= { a + bx+ cx^2} over { 1+dx+ex^2~ + fx^3} [lx]}}}} , where , a, b, c , d, e and of were arbitrary constants. 2. Maximum illumination of hat-covered lamp of 60 W was 1.2 -1.5 times as many as uncovered lamp. 3. Maximum illumination of yellow color painted lamp of 100 W was 1.3 times as many as unpainted lamp.

  • PDF

Synthesis and characterization of Ti-Cx-N1-x coatings prepared by arc ion plating (아크 이온 플레이팅법으로 증착된 $Ti-C_x-N_{1-x}$ 코팅막의 분석 및 특성 )

  • An, Seong-Gyu;Yun, Ji-Hwan;Kim, Gwang-Ho
    • Proceedings of the Korean Institute of Surface Engineering Conference
    • /
    • 2007.11a
    • /
    • pp.120-122
    • /
    • 2007
  • 3성분계 $Ti-C_x-N_{1-x}$ 코팅막은 AIP(Arc Ion Plating)법에 의해 -25V의 바이어스와 $300^{\circ}C$의 분위기에서 스테인리스 스틸 기판 위에 증착시켰다. $Ti-C_x-N_{1-x}$ 코팅막 안의 탄소(carbon)는 유입가스 비 $CH_4/(CH_4+N_2)$를 변화시키며 합성하였다. 탄소(carbon)가 증가함으로써, $Ti-C_x-N_{1-x}$ 코팅막의 미세경도는 TiN 코팅막의 20 GPa로부터 x=0.52에서 최대 약 32 GPa로 측정되었다. 또한, 미세구조는 잔류응력과 관련 있으며 탄소 함량에 따라 평균마찰계수가 크게 감소하였다.

  • PDF

WEAR AND CHEMICAL DEGRADATION OF ESTHETIC RESTORATIVE MATERIALS (차세대 레진 개발을 위한 광중합형 복합레진의 화학적 분해와 마모에 관한 연구)

  • Yang, Kyu-Ho;Choi, Eun-Young;Choi, Nam-Ki;Kim, Seon-Mi
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.32 no.3
    • /
    • pp.557-568
    • /
    • 2005
  • The aim of this study was to evaluate the resistance to degradation and to compare the wear resistance characteristics of four esthetic restorative materials in an alkaline solution(0.1N NaOH). The brands studied were MetafilCX(Sun medical, Japan) Solitaire 2(Heraeus Kulzer, USA), Composan LCM(Promedica, Germany), DenFil(Vericom, Korea). The results were as follows: 1. The mass loss of each brand was 0.74~7.94% and highest value in Metafil($7.94{\pm}0.39%$). 2. The sequence of the degree of degradation layer depth was in descending order by Metafil, Solitaire 2, DenFil, Composan LCM. There were significant differences between Metafil and the others(p<0.05). 3. The sequence of the Si loss was in descending order by Metafil, Solitaire 2, Composan LCM, DenFil. There were significant differences among the materials(p<0.05). 4. On SEM, destruction of bonding between matrix and filler and on CLSM, the depth of degradation layer of specimen surface was observed. 5. The sequence of maximum wear depth was in descending order by Metafil, Solitaire 2, Composan LCM and DenFil. There were significant differences among the materials(p<0.05). 6. The correlation coefficient between Si loss and degradation layer depth (r=0.491, p<0.05) and Vicker's hardness number and maximum wear depth (r=-0.942, p<0.05) were relatively high. These results indicate that hydrolytic degradation and wear may consider as a evaluation factors of composite resins.

  • PDF

Ring of Four Almonds and the Omar Khayyam's Triangle in Islamic Art Design (이슬람 예술 디자인에서 회전하는 알몬드와 오마르 하얌의 삼각형)

  • Park, Jeanam;Park, Mingu
    • Journal for History of Mathematics
    • /
    • v.32 no.4
    • /
    • pp.159-173
    • /
    • 2019
  • In this paper, we examine the brief history of the ring of four almonds regarding Mesopotamian mathematics, and present reasons why the Omar Khayyam's triangle, a special right triangle in a ring of four almonds, was essential for artisans due to its unique pattern. We presume that the ring of four almonds originated from a point symmetry figure given two concentric squares used in the proto-Sumerian Jemdet Nasr period (approximately 3000 B.C.) and a square halfway between two given concentric squares used during the time of the Old Akkadian period (2340-2200 B.C.) and the Old Babylonian age (2000-1600 B.C.). Artisans tried to create a new intricate pattern as almonds and 6-pointed stars by subdividing right triangles in the pattern of the popular altered Old Akkadian square band at the time. Therefore, artisans needed the Omar Khayyam's triangle, whose hypotenuse equals the sum of the short side and the perpendicular to the hypotenuse. We presume that artisans asked mathematicians how to construct the Omar Khayyam's triangle at a meeting between artisans and mathematicians in Isfahan. The construction of Omar Khayyam's triangle requires solving an irreducible cubic polynomial. Omar Khayyam was the first to classify equations of integer polynomials of degree up to three and then proceeded to solve all types of cubic equations by means of intersections of conic sections. Omar Khayyam's triangle gave practical meaning to the type of cubic equation $x^3+bx=cx^2+a$. The work of Omar Khayyam was completed by Descartes in the 17th century.

Evaluation of Image Quality using SE-EPI and SSH-TSE Techniques in MRDWI (자기공명확산강조영상에서 SE-EPI 와 SSH-TSE 기법을 이용한 영상의 질 평가)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
    • /
    • v.15 no.7
    • /
    • pp.991-998
    • /
    • 2021
  • The purpose of this study is to investigate the image quality of the SE-EPI and SSH-TSE technique for MR DWI. Datum were analyzed for 35 PACS transmission datum(Normal part: 12 males, 13 females, Cerebral Infarction: 10(5males and 5females), and average age 68±7.32), randomly selected patients who underwent MRDWI tests. The equipment used was Ingenia CX 3.0T, SSH_TSE and SE-EPI pulse sequence and 32 Ch. head coil were used for data acquisition. Image evaluation was performed on the paired t-test and Wilcoxon tests, and was considered significant when the p value was 0.05 or less. As a result of quantitative analysis of SNR for DWI images, the mean and standard deviation values of 4 parts (WM, GM, BG, Cerebellum) in ADC (s/mm2), Diffusion b=0, 1000 images were higher in SE-EPI techniques(ADC: 120.50 ± 40, b=0: 54.50 ± 35.91, b=1000: 91.61 ± 36.63) than in SSH-TSE techniques(ADC: 99.69 ± 31.10, b=0: 43.52 ± 25.00 , b=1000: 60.74 ± 24.85)(p<0.05). The CNR values for GM-WM, BG-WM sites were also higher in SE-EPI technique (ADC: 116.08 ± 43.30, b=0:27.23 ± 09.10, b=1000: 78.50 ± 16.56) than in SSH-TSE(ADC: 101.08 ± 36.81, b=0: 23.96 ± 07.79 , b=1000: 74.30 ± 14.22). As a visual evaluation of observers, ghost artifact, magnetic susceptibility artifacts and overall image quality for SE-TSE and SSH-TSE all yielded high results from SSH-TSE techniques(ADC:3.6 ± 0.1, 2.8 ± 0.2, b=0: 4.3 ± 0.3, 3.4 ± 0.1 b=1000: 4.3 ± 0.2, 3.5 ± 0.2, p=0.000). In conclusion, the SE-EPI technique obtained an superiority in SNR and CNR measurements using SSH-TSE, SE-EPI. In the qualitative analysis, the SSH-TSE pulse sequence was obtained a high result according to the pulse sequence characteristics.

Extract of Curcuma zedoaria R. prevents atherosclerosis in apolipoprotein E-deficient mice

  • Kim, Ki Mo;Lee, Joo Young;Jeon, Byeong Hwa;Quan, Khong Trong;Na, MinKyun;Nam, Kung-Woo;Chae, Sungwook
    • Nutrition Research and Practice
    • /
    • v.15 no.3
    • /
    • pp.319-328
    • /
    • 2021
  • BACKGROUND/OBJECTIVES: Curcuma zedoaria R. (Zingiberaceae) has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a C. zedoaria extract (CzE) affected atherosclerosis in vivo. MATERIALS/METHODS: Apolipoprotein E-deficient (ApoE-/-) mice (n = 32) were fed a normal diet (ND), a high-cholesterol diet (HCD), an HCD containing CzE (100 mg/kg/day), or an HCD containing simvastatin (10 mg/kg/day) for 12 weeks. The anti-atherosclerotic effects were evaluated by observing changes in fatty streak lesions, immunohistochemical analysis, ex vivo fluorescence imaging, lipid profiles, and western blot analysis. RESULTS: The CzE-fed group showed a 41.6% reduction of atherosclerosis. Furthermore, CzE significantly reduced the levels of serum triglyceride, high-density lipoprotein, the chemokine (C-X3-C-motif ) ligand 1, the adhesion molecules vascular cell adhesion molecule-1, intracellular adhesion molecule-1, and E-selectin; down-regulation of tumor necrosis factor-α, interleukin-6, high mobility group box-1, and cathepsin levels in the aortic sinuses and aortas of ApoE-/- mice were also observed. CONCLUSIONS: The results suggest that the inclusion of a water extract of C. zedoaria in a HCD is closely correlated with reducing the risk of vascular inflammatory diseases in an ApoE mouse model.

Total Serum Bile Acid as a Potential Marker for the Diagnosis of Cholangiocarcinoma without Jaundice

  • Sombattheera, Sutthikan;Proungvitaya, Tanakorn;Limpaiboon, Temduang;Wongkham, Sopit;Wongkham, Chaisiri;Luvira, Vor;Proungvitaya, Siriporn
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.4
    • /
    • pp.1367-1370
    • /
    • 2015
  • Diagnosis of cholangiocarcinoma (CCA) is difficult when patients do not show jaundice. The aim of this study was to examine the feasibility of using the total serum bile acid (TSBA) level as an aid for the diagnosis of CCA in patients without jaundice. For this purpose, TSBA of the following groups were measured using a Beckman Synchron CX4 clinical chemistry analyzer: 60 cases of CCA with total serum bilirubin ${\leq}2mg/dL$ (low total bilirubin group, LTB); 32 cases of CCA with total serum bilirubin >2 mg/dL (high total bilirubin group, HTB); and 115 healthy controls. Liver function parameters such as serum cholesterol, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were also examined. The results showed that the TSBA of both LTB and HTB groups of the CCA patients were significantly higher than that of the healthy controls. Also, significant correlation was observed between TSBA and total bilirubin levels in the HTB group of CCA patients. However, no such correlation was seen in the LTB group. The cut-off value of TSBA was determined for the LTB group of CCA patients using the receiver operating characteristic curve analysis, and it was $6.05{\mu}mol/L$ with the sensitivity and specificity of 46.7% and 84.4%, respectively. In addition, the ALP level was correlated well with the TSBA level and ALP in HTB group was significantly higher than that of LTB group. Moreover, the combination of high TSBA and high ALP levels gave higher specificity up to 97.4%. TSBA might be useful for the diagnosis of CCA patients without jaundice.