• 한국수산과학회지
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• 제49권6호
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• pp.838-844
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• 2016

In this study, epidemiological cut-off values were estimated for 44 Photobacterium damselae isolates, since clinical breakpoints have not been established for this pathogenic bacterium. The susceptibility of the isolates to 10 antibiotics was evaluated using internationally standardized disc diffusion protocols. Normalized resistance interpretation was used to generate statistically valid epidemiological cut-off values for the susceptibility data. There were not enough strains exhibiting full sensitivity to ampicillin and amoxicillin to allow analysis of these antibiotics. Because there were only a marginally sufficient number of strains exhibiting full sensitivity to oxytetracycline, the cut-off value generated provided only a provisional estimate. The valid wild-type cut-off values were <13, 13, 9, 22, 25, 27, and 28 mm for gentamicin, cephalexin, erythromycin, oxolinic acid, flumequine, florfenicol, and sulfamethoxazole/trimethoprim, respectively. The application of these cut-off values should greatly facilitate the rational selection of antibiotics for use in commercial fish farms.

• 대한한방소아과학회지
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• 제24권2호
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• pp.99-111
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• 2010

Objectives The objectives of this study were to evaluate the correlations between the indices of obesity and percentage body fat by bioelectrical impedance analysis(BIA). Also, this study was designed to define the cut off values of percentage body fat by BIA which would represent BMI and degree of obesity in order to detect overweight and obesity in preschool children. Methods The height and weight of 683 children aged four to six years old were measured. Also, percentages of body fat were measured by BIA. Results There were high correlations between the boy's body fat percentages and degree of obesity(r=790). Also, there were high correlations between the girl's body fatpercentages and BMI(r=778). The cut off values of body fat percentage, which would correspond to those of BMI percentiles, were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.55% in boys and 22.35% in girls. For obesity, the cut off values were 28.80% in boys and 27.60% in girls. The cut off values of body fat percentage, which would correspond to degree of obesity were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.75% in boys and 22.35% in girls. For obesity, the cut off values were 29.05% in boys and 28.75% in girls. Conclusions According to the BMI criteria by the Korean pediatrics society in 2007, the most appropriate cut off values of body fat percentage in for four to six years old children were follows; for boys, 19.55% considered as overweight, and 28.80% as obese while for girls, 22.35% considered as overweight and 27.60% as obese. According to suggested degree of obesity criteria, the most appropriate cut off values of body fat percentage in for four to six old children were were follows; For boys, 19.75% was considered as overweight, and 29.05% as obesity. For girls, 22.35% was considered as overweight, and 28.75% as obese.

• 대한한방소아과학회지
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• 제37권4호
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• pp.1-14
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• 2023

Objectives This study aimed to evaluate the correlation between pediatric weakness scale scores and growth indices. Furthermore, we intended to calculate the cut-off values for diagnosing Kidney Weak Children through growth indices. Methods A total of 193 patients, aged 6 - 12 years, underwent both the pediatric weakness scale and bone age assessment, and the correlations between the pediatric weakness scale and growth indices were analyzed. Moreover, the cut-off values for diagnosing Kidney Weak Children were calculated. Differences in bone age and predicted height between the normal group and Kidney Weak Children, classified according to the calculated cut-off values, were analyzed. Results The weakness of the Shin or kidney system was significantly correlated with the height percentile, weight percentile, differences in current height percentile and mid parental height percentile, differences in predicted height and mid parental height, and differences in bone age and chronological age. When the criteria for diagnosing Kidney Weak Children is set at "height percentile of ≤25% and weight percentile of ≤25%", the sensitivity and specificity of the cut-off value were maximized. The cut-off values for weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years. Conclusions To diagnose Kidney Weak Children, the cut-off values of weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years.

• 대한간호학회지
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• 제50권6호
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• pp.787-798
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• 2020

Purpose: This study aimed to assign weights for subscales and items of the Post-Intensive Care Syndrome questionnaire and suggest optimal cut-off values for screening unplanned hospital readmissions of critical care survivors. Methods: Seventeen experts participated in an analytic hierarchy process for weight assignment. Participants for cut-off analysis were 240 survivors who had been admitted to intensive care units for more than 48 hours in three cities in Korea. We assessed participants using the 18-item Post-Intensive Care Syndrome questionnaire, generated receiver operating characteristic curves, and analysed cut-off values for unplanned readmission based on sensitivity, specificity, and positive likelihood ratios. Results: Cognitive, physical, and mental subscale weights were 1.13, 0.95, and 0.92, respectively. Incidence of unplanned readmission was 25.4%. Optimal cut-off values were 23.00 for raw scores and 23.73 for weighted scores (total score 54.00), with an area of under the curve (AUC) of .933 and .929, respectively. There was no significant difference in accuracy for original and weighted scores. Conclusion: The optimal cut-off value accuracy is excellent for screening of unplanned readmissions. We recommend that nurses use the Post-Intensive Care Syndrome Questionnaire to screen for readmission risk or evaluating relevant interventions for critical care survivors.

• 사상체질의학회지
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• 제26권4호
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• pp.365-378
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• 2014

Objectives This study was performed to investigate the cut-off values of abdominal circumference and Body Mass Index(BMI) according to Sasang Constitution. Methods A total of 1,773 persons, namely 440 male people and 1,333 female people, in ages from 40 to 69 years old, participated in this research. They are all included in the community based Genomic cohort in Wonju in years from 2006 to 2013. The diagnostic criteria of metabolic syndrome was used followed by the National Cholesterol Education Program in Adult Treatment Panel III (NCEP ATP III) and Asian pacific guideline for only abdominal obesity. Results The prevalence of metabolic syndrome was 34.8% for men and 37.6% for women in this research. Taeeumin was the highly significant risk type for the metabolic syndrome in both sexes. Cut-off values of abdominal circumference were 88.3 cm in men, 80.3 cm in women, and cut-off values of BMI were $24.2kg/m^2$ in men and $25.3kg/m^2$ in women. For men, cut-off values of abdominal circumference were 79.5cm in Soyangin, 88.8 cm in Taeeumin and 79.5 cm in Soeumin, and cut-off values of BMI were $23.2kg/m^2$ in Soyangin, $25.6kg/m^2$ in Taeeumin and $20.6kg/m^2$ in Soeumin. For women, cut-off values of abdominal circumference were 76.3 cm in Soyangin, 80.3 cm in Taeeumin and 76.8 cm in Soeumin, and cut-off values of BMI were $22.4kg/m^2$ in Soyangin, $24.9kg/m^2$ in Taeeumin and $21.3kg/m^2$ in Soeumin. Conclusions Although 90 cm in men, 80 cm in women as an Asian pacific guideline were regarded as quite approximate to the mean value of abdominal circumference and $25kg/m^2$ to BMI. But if the results could be allocated in terms of the Sasang constitutional method, the cut-off values for Soyangin and Soeumin should be lowered than now.

• 분석과학
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• 제34권2호
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• pp.78-86
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• 2021

The objective of this study was to investigate urinary cut-off concentrations of quetiapine and risperidone for distinction between normal and abnormal/non-takers who were being placed on probation. Liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was employed for determination of antipsychotic drugs in urine from mentally disordered probationers. The optimal cut-off values of antipsychotic drugs were calculated using receiver operating characteristic (ROC) curve analysis. The sensitivity and specificity of the method for the detection of antipsychotic drugs in urine were subsequently evaluated. The area under the ROC curve (AUC) was 0.927 for norquetiapine and 0.791 for 9-hydroxyrisperidone, respectively. These antipsychotic drugs are classified readily in the ROC curve analysis. The cut-off values for distinguishing regular and irregular/non-takers were 39.1 ng/mL for norquetiapine and 67.9 ng/mL for 9-hydroxyrisperidone, respectively. The results of this study suggest the cut-off values of quetiapine and risperidone were highly useful to distinguish regular takers from irregular/non-takers.

• 대한한방소아과학회지
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• 제24권3호
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• pp.58-67
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• 2010

Objectives: The objective of this study was to evaluate the correlations between the Weak Children Questionnaire result and K-CBCL score. Also, this study was designed to define the cut off values of Heart Weak Scores by using 'K-CBCL' which represents the total behavior problems scores 50T in order to detect Heart Weak in Children Methods: 271 elementary school students in Daejeon answered the questionnaire and the data was analyzed. Results: There were high correlations between Heart Weak Score and K-CBCL which in a total behavior problems scores. The cut off values of Heart Weak Score, K-CBCL, a total behavior problems scores 50T, were calculated by ROC curve analysis. To diagnose as a Heart Weak Children, the correspondent cut off values for Heart Weak Score were 11 in boys and 8 in girls. Conclusions: To diagnose as a Heart Weak in Children, the correspondent cut off values for Heart Weak Score were 11 in boys and 8 in girls.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5455-5459
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• 2013

Background: The risk of malignancy index (RMI) for the evaluation of adnexal masses is a sensitive tool in certain populations. The best cut off value for RMI 1, 2 and 3 is 200. The cut off value of RMI-4 to differentiate benign from malignant lesions is 450. Our aim was to evaluate the efficiency of four different malignancy indexes (RMI1-4) in a homogeneous population. Materials and Methods: We evaluated a total of 153 non-pregnant women with adnexal masses who did not have a history of malignancy and who were above 18 years of age. Results: A cut-off value of 250 for RMI-1 provided 95.9% inter-observer agreement, yielding 95.9% specificity, 93.5% negative predictive value, 75.0% sensitivity and 82.8% positive predictive value. A cut-off value of 250 for RMI-1 showed high performance in preoperative diagnosis of invasive malignant lesions than cut-off value of 200 in our population. A cut-off value of 350 for RMI-2 provided 94.5% inter-observed agreement, yielding 94.2% specificity, 93.4% negative predictive value, 75.0% sensitivity and 77.4% positive predictive value. RMI-2 showed the higher performance when the cut-off value was set at 350 in our population. A cut-off value of 250 provided 95.2% inter-observer agreement, yielding 95.0% specificity, 93.2% negative predictive value, 75.0% sensitivity, and 88.0% positive predictive value. RMI-3 showed the highest performance to diagnose malignant adnexal masses when the cut-off value was set at 250. In our study, RMI-4 showed similar statistical performance when the cut-off value was set at 400 [(Kappa: 0.684/p=0.000), yielding 93.8% inter-observer agreement, 93.4% specificity, 93.4% negative predictive value, 75.0% sensitivity, and 75.0% negative predictive value]. Conclusions: We showed successful utilization of RMIs in preoperative differentiation of benign from malignant masses. Many studies conducted in Asian and Pacific countries have reported different cut-off values as was the case in our study. We think that it is difficult to determine universally accepted cut-off values for RMIs for common use around the globe.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.497-501
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• 2016

Aim: To evaluate the relationship between pre-operative CA-125 levels and myometrial invasion in patients with early-stage endometrioid-type endometrial cancer. Materials and Methods: Two-hundred and sixty patients were diagnosed with endometrial cancer between January 2007 and December 2012. Of these, 136 patients with stage 1 endometrioid histologic-type and documented pre-operative serum CA-125 levels were included in the study. Age, preoperative CA-125 level, histologic grade, surgical grade, and presence of deep myometrial invasion were recorded. Additionally, 16, 20, and 35 IU/ml cutoff values were used and compared to evaluate the relationship between pre-operative CA-125 levels and myometrial invasion. Results: The average serum CA-125 level was $35.4{\pm}36.7$ in patients with deep myometrial invasion, and $21.5{\pm}35.8$ in cases without deep myometrial invasion. The relationship between the presence of deep myometrial invasion and CA-125 cut-off values (16, 20, 35 IU/ml) was statistically significant, although the correlation was weak (p<0.05). When the relationship between 16, 20 and 35 IU/ml CA-125 cut-off values and the presence of deep myometrial invasion was studied, specifity and sensitivity values were identified as: 0.60-0.68 for 16 IU/ml; 0.73-0.48 for 20 IU/ml; and 0.89-0.33 for 35 IU/ml. The sensitivity of 16 IU/ml cut-off value was higher when compared to other values. Conclusions: This study demonstrates that preoperative serum CA-125 values maybe used as a predictive test in patients with early stage endometrioid-type endometrium cancer, and as a prognostic factor alone. Further studies should be conducted to identify different CA-125 cut-off values in patients with low risk endometrial cancer.

• 대한기계학회논문집B
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• 제26권10호
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• pp.1341-1347
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• 2002

In order to improve efficiency of a system with three-dimensional flow characteristics, this paper presents a new method that overcomes three-dimensional effects by using two-dimensional CFD and neural network. The method was applied to shape optimization of cut-off in a multi-blade fan/scroll system. As the entrance conditions of two-dimensional CFD, the experimental values at the positions out of the inactive zone were used. The distributions of velocity and pressure obtained by two-dimensional CFD were compared with those of three-dimensional CFD and experimental results. It was found that the distributions of velocity and pressure have qualitative similarity. The results of two-dimensional CFD were used for teaming as target values of neural network. The optimal angle and radius of cut-off were determined as 71$^{\circ}$and 0.092 times the outer diameter of impeller, respectively. It is quantified in the previous report that the optimal angle and radius of cut-off are approximately 72$^{\circ}$and 0.08 times the outer diameter of impeller, respectively.