• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1467-1470
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• 2003

In order to enhance the productivity of design and manufacture of injection molds, various computer-aided systems have been developed and introduced to mold manufacturers. The customized 3-D CAD systems for mold design is one of the most representative computer-aided system. However, these systems usually do not provide a convenient way to access and manage design knowledge implemented in them. To overcome this shortage, knowedge-based engineering systems have been developed, and now they are imbedded as modules of commercial CAD systems. In this paper, we introduced a 3-D design system for standard mold base based on Knowledge Fusion, a commercialized KBE system imbedded in Unigraphics. By introducing KBE system, design knowledge can be exposed to the users and modified by the end-users.

• 디지털융복합연구
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• 제14권1호
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• pp.1-11
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• 2016

현재 우리 정부는 플랫폼 전자정부 도입을 서두르고 빅데이터와 클라우드 컴퓨팅 기술과 시스템을 모색하여 궁극적으로는 공공기관 각각의 이종 대민서비스를 단일창구에서 맞춤형으로 제공하고자 한다. 따라서 이 연구에서는 창구의 프런트오피스 민원인의 다양한 서비스 제공요청에 대응해서 백오피스에서 단일한 방식으로 맞춤형 공공서비스를 제공하기 위해서는 먼저 백오피스 차원에서 공공데이터가 연동되어야하므로 각 행정기관이나 부처의 공공데이터를 기반으로 백오피스에서 통합차원에서 민원인에 대해서 단일한 서비스를 제공할 수 있는 별도의 응용프로그램으로서 앱과 데이터 단위에서 공유를 효율적으로 수행하는 이종서비스 상호 간의 정보시스템 통합이 가능한 새로운 메타데이터정보시스템을 제안하였다. 제안된 시스템이 구현되면, 민원인의 프런트오피스 차원의 생활공간에 존재하는 서비스 수요사슬과 백오피스 차원의 공무원의 사무공간에서 이루어지는 서비스 공급사슬의 일원화를 통한 단일 창구에서의 연동이 유기적으로 되면서, 민원인에 대한 맞춤형 공공서비스 달성을 한발 앞당길 수 있다.

• 정보교육학회논문지
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• 제4권2호
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• pp.223-231
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• 2001

하이퍼미디어 문서들은 문서의 구조 정보를 포함하고 있다. 이러한 구조 정보를 이용하여 하이퍼미디어 문서를 저장, 검색하기 위한 모델에 관한 연구가 있어 왔다. 그러나 실제 문서의 상연을 지원하기 위한 모델의 제시가 미비한 실정이다. 본 논문에서는 HyTime 하이퍼미디어 문서를 문서의 구조정보를 이용하여 객체지향 모델링을 하여 상연을 효율적으로 수행할 수 있는 방안을 제안한다. 이를 위하여 HyTime의 응용으로 사용자의 요구에 맞게 뉴스를 제공하는 주문형 뉴스 서비스를 지원하는 시스템을 고려한다. 본 논문에서 제안한 모델링은 주문형 뉴스 서비스뿐만 아니라, 멀티미디어를 지원하는 주문형 웹 기반 교육, 디지털 도서관 등의 하이퍼미디어 응용 분야에서 활용될 수 있을 것이다.

• Genomics & Informatics
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• 제15권4호
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• pp.136-141
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• 2017

Accurate detection of genomic alterations, especially druggable hotspot mutations in tumors, has become an essential part of precision medicine. With targeted sequencing, we can obtain deeper coverage of reads and handle data more easily with a relatively lower cost and less time than whole-exome or whole-genome sequencing. Recently, we designed a customized gene panel for targeted sequencing of major solid cancers. In this study, we aimed to validate its performance. The cancer panel targets 95 cancer-related genes. In terms of the limit of detection, more than 86% of target mutations with a mutant allele frequency (MAF) <1% can be identified, and any mutation with >3% MAF can be detected. When we applied this system for the analysis of Acrometrix Oncology Hotspot Control DNA, which contains more than 500 COSMIC mutations across 53 genes, 99% of the expected mutations were robustly detected. We also confirmed the high reproducibility of the detection of mutations in multiple independent analyses. When we explored copy number alterations (CNAs), the expected CNAs were successfully detected, and this result was confirmed by target-specific genomic quantitative polymerase chain reaction. Taken together, these results support the reliability and accuracy of our cancer panel in detecting mutations. This panel could be useful for key mutation profiling research in solid tumors and clinical translation.

• 대한조선학회 특별논문집
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• 대한조선학회 2009년도 특별논문집
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• pp.40-46
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• 2009

The GSCAD (Global Shipbuilding CAD) System used in Samsung Heavy Industries is based on the Relation and Rule. The design area where excellence of these Relation & Rule can be used fully is pipe support modeling. That's because, many rules are required to place a pipe support and it's supported by hull structural object. Samsung Heavy Industries has been customizing the Relation and Rule supported by SmarMarine3d(R) to model pipe support easily and satisfies standard. Also, the pipe support fabrication drawing program was developed to generate a drawing for the pipe support customized. This paper reviews the characteristics of pipe support modeling on GSCAD and the Rules customized also, fabrication drawing program will be introduced.

• 전기학회논문지
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• 제57권7호
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• pp.1298-1303
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• 2008

Respiration is induced by muscular contraction of the chest and abdomen, resulting in the abdominal volume change. Thus, continuous measurement of the abdominal dimension enables to monitor breathing activity. Conductive rubber cord has been previously introduced and tested to develop wearable application for respiratory measurements. This study implemented respiratory monitoring system with the conductive rubber cord in the patient's pants in purpose of quantitative estimation of tidal volume. Air mixed with $0{\sim}5%$ $CO_2$ was inhaled and the respiratory air flow rate, abdominal dimension change, and end tidal $CO_2$ concentration were simultaneously measured in steady state. $CO_2$ inhalation significantly increased the tidal volume in normal physiological state with the subject unawared. The tidal volume estimated from the abdominal dimension change linearly correlated with the tidal volume measured by a pneumotachometer with a correlation coefficient of 0.88. Customized calibration for each subject resulted in relative errors less than 10%. Therefore, the tidal volume was accurately estimated by measuring the abdominal dimension change.

• Nuclear Medicine and Molecular Imaging
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• 제42권5호
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• pp.337-346
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• 2008

Applications of nanotechnology in the medical field have provided the fundamentals of tremendous improvement in precise diagnosis and customized therapy. Recent advances in nanomedicine have led to establish a new concept of theragnosis, which utilizes nanomedicines as a therapeutic and diagnostic tool at the same time. The development of high affinity nanoparticles with large surface area and functional groups multiplies diagnostic and therapeutic capacities. Considering the specific conditions related to the disease of individual patient, customized therapy requires the identification of disease target at the cellular and molecular level for reducing side effects and enhancing therapeutic efficiency. Well-designed nanoparticles can minimize unnecessary exposure of cytotoxic drugs and maximize targeted localization of administrated drugs. This review will focus on major pharmaceutical nanomaterials and nanoparticles as key components of designing and surface engineering for targeted theragnostic drug development.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권6호
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• pp.297-303
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• 2013

Alloplastic total replacement of the temporomandibular joint (TMJ) was developed in recent decades. In some conditions, previous studies suggested the rationale behind alloplastic TMJ replacement rather than reconstruction with autogenous grafts. Currently, three prosthetic products are available and approved by the US Food and Drug Administration. Among these products, customized prostheses are manufactured, via computer aided design/computer aided manufacturing (CAD/CAM) system for customized design; stock-type prostheses are provided in various sizes and shapes. In this report, two patients (a 50-year-old female who had undergone condylectomy for the treatment of osteochondroma extending to the cranial base on the left condyle, and a 21-year-old male diagnosed with left temporomandibular ankylosis) were treated using the alloplastic total replacement of TMJ using stock prosthesis. The follow-up results of a favorable one-year, short-term therapeutic outcome were obtained for the alloplastic total TMJ replacement using a stock-type prosthesis.

• 한국CDE학회논문집
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• 제14권3호
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• pp.186-196
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• 2009

Mass customization (MC) is a business practice that aims to provide customers with customized products and services at near mass production efficiency. To achieve the aim, a number of methods to implementing MC are proposed. However, most of them require changes in entire process of the company, which make companies hesitate to implement MC even if it is essential to survive. In this paper, we proposed alternatives to partially implement MC for quick adaptation of MC. The base line assumption is not to change the production lines. The pros and cons of alternatives are given by qualitative and quantitative evaluation. Especially, by giving radar chart analysis of the quantitative measures, we give insight on the changes in the business performance measures, such as time to market and cost. Proposed alternatives are based on sub-processes such as purchasing raw materials, production process changes and packaging for efficient logistics. In this way, companies are able to provide customized products with small changing of the current manufacturing system. The process and benefit of the proposed strategy is verified by real world cases of a Korean health food company.

• International Journal of Internet, Broadcasting and Communication
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• 제14권2호
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• pp.36-39
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• 2022

Medical tourism is recognized as a high value-added industry due to its longer stay and more useful costs than general tourism, and is growing rapidly around the world, especially in Asia. In addition, medical tourism is a new form of tourism that combines medical services with tourism activities such as recreation, leisure, and cultural activities, nowadays, medical tourism is emphasizing the combination of medical and tourism. Although Korea medical system and clinic have excellent medical equipment and infrastructure, it is not consistent with policy support and legislation. That have make it difficult for consumers to choose clinics for medical tourism. Therefore, it is necessary to provide customized information to the clinics that consumers want to match each other's services. In particular, it is aimed at consumers with simple procedures and cosmetic purposes, especially at small hospitals. In this paper, we propose a customized service platform that matches users seeking clinics and also medical tourism. Also we can easy to reservation clinic for medical tour.