International Journal of Computer Science & Network Security
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v.22
no.6
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pp.390-399
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2022
Cyber security and resilience are phrases that describe safeguards of ICTs (information and communication technologies) from cyber-attacks or mitigations of cyber event impacts. The sole purpose of Risk models are detections, analyses, and handling by considering all relevant perceptions of risks. The current research effort has resulted in the development of a new paradigm for safeguarding services offered online which can be utilized by both service providers and users. customers. However, rather of relying on detailed studies, this approach emphasizes task selection and execution that leads to successful risk treatment outcomes. Modelling intelligent CSGs (Cyber Security Games) using MLTs (machine learning techniques) was the focus of this research. By limiting mission risk, CSGs maximize ability of systems to operate unhindered in cyber environments. The suggested framework's main components are the Threat and Risk models. These models are tailored to meet the special characteristics of online services as well as the cyberspace environment. A risk management procedure is included in the framework. Risk scores are computed by combining probabilities of successful attacks with findings of impact models that predict cyber catastrophe consequences. To assess successful attacks, models emulating defense against threats can be used in topologies. CSGs consider widespread interconnectivity of cyber systems which forces defending all multi-step attack paths. In contrast, attackers just need one of the paths to succeed. CSGs are game-theoretic methods for identifying defense measures and reducing risks for systems and probe for maximum cyber risks using game formulations (MiniMax). To detect the impacts, the attacker player creates an attack tree for each state of the game using a modified Extreme Gradient Boosting Decision Tree (that sees numerous compromises ahead). Based on the findings, the proposed model has a high level of security for the web sources used in the experiment.
Journal of the Korea Institute of Building Construction
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v.22
no.2
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pp.183-194
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2022
This study conducted a survey for BIM experts as a basic study to improve the efficiency of a BIM-based review of the BF certification evaluation method. By limiting the buildings to elementary schools, the first survey was conducted to extract the mandatory facilities from the BF certification evaluation items according to the evaluation criteria, and 63 out of a total of 94 evaluation items were extracted. The extracted facilities were intermediary facilities, internal facilities, and sanitary facilities. The second survey provided detailed calculation criteria for BF certification evaluation items, and through investigating the possibility of BIM-based review, 31 items were derived. In the 3rd and final survey, when asked about the effectiveness of the current CAD-based and BIM-based evaluation methods, the BIM-based evaluation method showed 96.8% effectiveness and the CAD-based evaluation method showed 3.2% effectiveness.
Wetland also known as "Jheelon" in Hindi language is one of the most important natural resources, contributing various economic and ecological benefits. The study gave a short review of the current status of Ramsar wetlands in India. The wildlife species, conservation measures, and their significance in Indian wetlands were also explored in this review paper. As of 2022, there are 49 Ramsar sites in India covering approximately 1,09363.6 km2 of land. The largest Ramsar wetland is Sundarbans, while the smallest is Chandertal. It was found that preventing wetland loss is important even though studies about wetland degradation in various nations including India, caused directly by human activities is still limited. Since Monitoring and protecting natural wetlands, supporting scientific studies on preservation and restoration of wetlands, demand on imposing regulations for limiting pollutant discharges were recommended allowing researchers, policymakers, and practitioners to better maintain wetland and its ecosystem services.
Regulatory T cells (Treg) naturally rein in immune attacks, and they can inhibit rejection of transplanted organs and even reverse the progression of autoimmune diseases in mice. The initial safety trials of Treg against graft-versus-host disease (GVHD) provided evidence that the adoptive transfer of Treg is safe and capable of limiting disease progression. Supported by such evidence, numerous clinical trials have been actively investigating the efficacy of Treg targeting autoimmune diseases, type I diabetes, and organ transplant rejection, including kidney and liver. The limited quantity of Treg cells harvested from peripheral blood and subsequent in vitro culture have posed a great challenge to large-scale clinical application of Treg; nevertheless, the concept of CAR (chimeric antigen receptor)-Treg has emerged as a potential resolution to the problem. Recently, two CAR-T therapies, tisagenlecleucel and axicabtagene ciloleucel, were approved by the US FDA for the treatment of refractory or recurrent acute lymhoblastic leukemia. This approval could serve as a guideline for the production protocols for other genetically engineered T cells for clinical use as well. The phase I and II clinical trials of these agents has demonstrated that genetically engineered and antigen-targeting T cells are safe and efficacious in humans. In conclusion, both the promising results of Treg cell therapy from the clinical studies and the recent FDA approval of CAR-T therapies are paving the way for CAR-Treg therapy in clinical use.
Sami Aftab Abdul;Frances Wright;Christian Finley;Sebastien Gilbert;Andrew J. E. Seely;Sudhir Sundaresan;Patrick J. Villeneuve;Donna Elizabeth Maziak
Journal of Chest Surgery
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v.56
no.6
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pp.420-430
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2023
Background: This study provides an update to a landmark 2004 report describing demographics, training, and trends in adherence to thoracic surgery practice standards in Canada. Methods: An updated questionnaire was administered to all members of the Canadian Association of Thoracic Surgeons via email (n=142, compared to n=68 in 2004). Our report incorporates internal data from Ontario Health and the Canadian Partnership Against Cancer. Results: Forty-eight surgeons completed the survey (male, 70.8%; mean±standard deviation age, 50.3±9.3 years). This represents a 33.8% response rate, compared to 64.7% in 2004. Most surgeons (69%) served a patient population of over 1 million per center; 32%-34% reported an on-call ratio of 1:4-1:5 days, and the average weekly hours worked was 56.4±11.9. Greater access to dedicated geographic units per center (73% in 2021 vs. 53% in 2004) has improved thoracic-associated services and house staff, notably endoscopy units (100% vs. 91%), with 73% of respondents having access to both endobronchial and endoscopic ultrasound. Access to thoracic radiology has also improved, particularly regarding positron emission tomography scanners per center (76.9% vs. 13%). Annual case volumes for lung (255 vs. 128), esophageal (41 vs. 19), and mediastinal resections (30 vs. 13), along with hiatal hernia repair (45 vs. 20), have increased substantially despite reports of operating room availability and radiology as rate-limiting steps. Conclusion: This survey characterizes compliance with current practice standards, addressing the needs of thoracic surgeons across Canada. Over 85% of respondents were aware of the 2004 compliance paper, and 35% had applied for resources and equipment in response.
The below-the-knee arterial tree is the thinnest of all the leg vessels and is an important path for blood flow to the foot. Hence, lesions including stenosis, especially obstruction, may lead to critical limb ischemia which represents the most severe clinical manifestation of peripheral arterial disease. It is characterized by the presence of ischemic rest pain, ischemic lesions, or gangrene attributable to the objectively proven arterial occlusive disease. Typically, the atherosclerotic disease process involving the below-the-knee arterial tree is diffuse in the majority of patients. The cornerstone of therapy is vascular reconstruction and limb salvage. Revascularization should be attempted whenever technically possible, without delay, in patients presenting critical limb ischemia and when the clinical status is not hopelessly non-ambulatory. Therefore, endovascular treatment can become the gold standard for the full range of patients including below-the-knee, limiting the clinical role of the classically trained surgeons.
Kim, Jong-Hyun;Korea Aerospace University, Jae-Seong;Lee, Jung;Kwag, No-Gwon;Lee, Bo-Young
Journal of the Korean Society for Nondestructive Testing
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v.29
no.5
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pp.485-492
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2009
The thermal fatigue crack(TFC) is one of the life-limiting mechanisms at the nuclear power plant operating conditions. In order to evaluate the structural integrity, various non-destructive test methods such as radiographic test, ultrasonic test and eddy current are used in the industrial field. However, these methods have restrictions that defect detection is possible after the crack growth. For this reason, acoustic emission testing(AET) is becoming one of powerful inspection methods, because AET has an advantage that possible to monitor the structure continuously. Generally, every mechanism that affects the integrity of the structure or equipment is a source of acoustic emission signal. Therefore the noise filtering is one of the major works to the almost AET researchers. In this study, acoustic emission signal was collected from the pipes which were in the successive thermal fatigue cycles. The data were filtered based on the results from previous experiments. Through the data analysis, the signal characteristics to distinguish the effective signal from the noises for the TFC were proven as the waveform difference. The experiment results provide preliminary information for the acoustic emission technique to the continuous monitoring of the structure failure detection.
Kim, Yoon-Ha;Moon, Chang-Ho;Choi, Kwang-Ho;Lee, Chung-Il
Journal of the Korean Society of Marine Environment & Safety
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v.16
no.3
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pp.259-268
/
2010
Data on squid catches by the Korean jig fishery in sea blocks ($30'{\times}30'$), water temperatures at depth(30m, 50m and 100m) and zooplankton biomass in the East Sea from 1980 to 1999 were analyzed to examine the mechanism of formation of the high density stock area. Japanese common squid (Todarodes pacificus) catch in the East Sea was low in 1980s, while the catch was high in 1990s. The five sea blocks (No. 76, 82, 83, 87, 88) of the southern part in the eastern coastal waters of Korea showed high levels of percentage of total catch (35.1%), whereas the four sea blocks (No. 65, 71, 72, 78) of the coastal waters of Uleung Island showed high levels of percentage of CPUE (61.2%) for 20 years. Squid catches showed monthly fluctuations according to the vertical distribution of optimum water temperature for fishing ($14^{\circ}C{\sim}19^{\circ}C$). High total catch and high CPUE area matched well with $10^{\circ}C$ isothermal lines at 100m depth indicating northern limiting of Tsushima Warm Current, and temporal and spatial change in $10^{\circ}C$ isothermal line caused the change in total catch and CPUE. Horizontal distribution of zooplankton biomass by sea block was not matched well with those of total catch and CPUE, however pattern of time-series change in total zooplankton biomass was similar to that in total squid catch.
Park, Il-Soo;Woon, Yu;Chung, Kyung-Won;Lee, Gangwoong;Owen, Jeffrey S.;Kwon, Won-Tae;Yun, Won-Tae
Journal of Korean Society for Atmospheric Environment
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v.30
no.2
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pp.188-200
/
2014
The IPCC 5th Assessment Report (Climate Change 2013: The Physical Science Basis) was accepted at the 36th Session of the IPCC on 26 September 2013 in Stockholm, Sweden. It consists of the full scientific and technical assessment undertaken by Working Group I. This comprehensive assessment of the physical aspects of climate change puts a focus on those elements that are relevant to understand past, document current, and project future of climate change. The assessment builds on the IPCC Fourth Assessment Report and the recent Special Report on Managing the Risk of Extreme Events and Disasters to Advance Climate Change Adaptation. The assessment covers the current knowledge of various processes within, and interactions among, climate system components, which determine the sensitivity and response of the system to changes in forcing, and they quantify the link between the changes in atmospheric constituents, and hence radiative forcing, and the consequent detection and attribution of climate change. Projections of changes in all climate system components are based on model simulations forced by a new set of scenarios. The report also provides a comprehensive assessment of past and future sea level change in a dedicated chapter. The primary purpose of this Technical Summary is to provide the link between the complete assessment of the multiple lines of independent evidence presented in the main report and the highly condensed summary prepared as Policy makers Summary. The Technical Summary thus serves as a starting point for those readers who seek the full information on more specific topics covered by this assessment. Warming of the climate system is unequivocal, and since the 1950s, many of the observed changes are unprecedented over decades to millennia. The atmosphere and ocean have warmed, the amounts of snow and ice have diminished, sea level has risen, and the concentrations of greenhouse gases have increased. Total radiative forcing is positive, and has led to an uptake of energy by the climate system. The largest contribution to total radiative forcing is caused by the increase in the atmospheric concentration of $CO_2$ since 1750. Human influence on the climate system is clear. This is evident from the increasing greenhouse gas concentrations in the atmosphere, positive radiative forcing, observed warming, and understanding of the climate system. Continued emissions of greenhouse gases will cause further warming and changes in all components of the climate system. Limiting climate change will require substantial and sustained reductions of greenhouse gas emissions. The in-depth review for past, present and future of climate change is carried out on the basis of the IPCC 5th Assessment Report.
Kim, Jung-Soo;Choi, Hong-Ryul;Chung, Dae-Sung;Lee, Youn-Suk
Horticultural Science & Technology
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v.28
no.5
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pp.902-911
/
2010
Oriental melon ($Cucumis$$melo$ var. $makuwa$) is a popular and high-value market fruit cultivated in Korea. Consumers are becoming increasingly interested in oriental melon as a healthy diet over the past few years. However, the melons have relatively high quality loss because the fruit are mainly produced for a limited period of time in the summer season. Lack of the proper postharvest treatments and high temperature exposure at harvest or during distribution are the most critical environmental factors limiting postharvest life of fruit. This review focuses on the overview of current research studies for postharvest treatment and functional packaging technology of oriental melon in Korea. Major physiological problems of the harvest fruit include the ripening process in quality changes of the produce such as loss of weight, firmness, flavor, and decay during the storage periods. Low temperature at 7 to $10^{\circ}C$ with high relative humidity of 90 to 95% is the suitable environmental condition used to maintain the quality of fresh oriental melon. Controlled atmosphere (CA) storage or modified atmosphere (MA) packaging can be used as supplemental treatments to extend postharvest-life. For oriental melon, an optimum CA is currently recommended to be 2-3% oxygen and 5-10% carbon dioxide atmosphere. Precooling, pretreatments of ethylene action and functional packaging system can be applied to oriental melon after harvest in order to extend storage life. Major active packaging technologies are concerned with a selectively gas permeable film related to respiration of produce and the packaging applications of ethylene removal, antimicrobial, and antifogging substances to keep the effective freshness of fruit.
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