• Journal of Preventive Medicine and Public Health
• /
• 제32권4호
• /
• pp.526-537
• /
• 1999

Objectives : It is known that the prevalence of diabetes mellitus(DM) appears to be rapidly increasing in recent times in Korea, presumably due to a westernized diet and change of life style followed by rapid economic growth. Based on the Seoul male cohort which was constructed in 1993, this study was conducted to estimate the annual incidence rates of DM through 4 years' follow up and to determine which factors are associated with DM risk in Korean middle-aged men. Methods : Among 14,533 men recruited at baseline, 559 were excluded because they reported a history of diabetes or were found to be diabetes at 1992 routine health examination. During 4 years' follow-up, 237 incident DM cases were ascertained through chart reviews and telephone contacts for those who have ever visited hospitals or clinics under suspicion of DM during 1993-1996 and the biennial routine health examinations in 1994 and 1996. Results : In this study the annual incidence of DM among the study population was estimated to be 0.5 per 100. This study showed that fasting glucose level at initial baseline examination was a powerful predictor of risk for diabetes several years later(fasting blood glucose of $\geq$ 110 mg/dl compared with $\leq$ 80 mg/dl, Hazard Ratio[HR]:15.6, 95% Confidence interval[CI]=9.1-26.6) after considering potential covariates such as age, family history, smoking and alcohol history, body mass index, physical activity, total energy intake, and total fiber intake. Adjusted hazard ratios of family history of diabetes was 1.95(95% CI=1.38-2.75); of obesity as measured by BMI(BMI $\geq$ 25.3 compared with $\leq$ 21.3) was 7.19(95% CI=3,75-13.8); of weight change during middle life(>10kg compared with $\leq$ 5) was 1.77(95% CI=1.16-2.69); of smoking(current vs none) was 1.93(95% CI=1.06-3.51); and fat intake(upper fertile compared with lower fertile) was 1.88(95% CI=1.01-3.49), while fiber intake was associated with the reduced risk(HR=0.36, 95% CI=0.19-0.67). Conclusion : The factors identified in this study indicate that the greatest reduction in risk of diabetes might be achieved through population-based efforts that promote fiber intake and reduce obesity, smoking, and fat intake.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권3호
• /
• pp.1233-1239
• /
• 2014

Background: The incidence of brain metastases (BM) varies in patients with non-small cell lung cancer (NSCLC), calls into question the value of prophylactic cranial irradiation (PCI). It is possible that clinicopathologic characteristics are associated with the development of BM, but these have yet to be identified in detail. Thus, we conducted the present meta-analysis on risk factors for BM and the value of PCI in patients with NSCLC. Methods: Eligible data were extracted and the risk factors for BM and the value of PCI in patients with NSCLC were analyzed by calculating the pooled odds ratio (OR). Heterogeneity was detected using Q and I-squared statistics, and publication bias was tested by funnel plots and Egger's test. Results: Six randomized controlled trials with a focus on the value of PCI and 13 eligible studies with a focus on risk factors for BM were included. PCI significantly reduced the incidence of BM in patients with NSCLC (p=0.000, pooled OR=0.34, 95% confidence interval = 0.37-0.59). Compared with non-squamous cell carcinoma, squamous cell carcinoma was associated with a low incidence of BM in patients with NSCLC (p=0.000, pooled OR=0.47, 95% confidence interval =0.34-0.65). The funnel plot and Egger's test suggested that there was no publication bias in the current meta-analysis. Conclusions: This meta-analysis provides statistical evidence that compared with non-squamous cell carcinoma, squamous cell carcinoma can be used as a predictor for BM in patients with NSCLC, and PCI might reduce the incidence of BM in patients with NSCLC, but does not provide a survival benefit.

• 한국방사선학회논문지
• /
• 제15권7호
• /
• pp.1021-1030
• /
• 2021

국내 결핵 환자 관리의 방안을 모색하고 결핵 정책의 기초자료를 제공하고자 2010년부터 2018년까지 통계청과 질병관리본부의 결핵 환자 통계 연보와 세계보건기구(WHO; World Health Organization)의 GLOBAL Tuberculosis Report 등의 자료를 수집하여, 국내 결핵 환자 현황을 분석하였다. 결과는 다음과 같다. 첫째, 국내 결핵 환자 발생 현황 결과는, 2018년 33,796명(65.9%), 신환자는 2018년 26,433명(51.5%)으로 약 21.3% 감소한 것으로 나타났다. 둘째, 국내 결핵 환자치료 현황은 과거 치료결과 불명확은 2018년 655명으로 2014년 대비 약 160% 증가한 것으로 나타났다. 셋째, 청소년 결핵환자 발생률은 10에서 14세는 2018년 1.8%, 15세에서 19세는 15.0%로 고등학생의 결핵 발생률이 높았다. 넷째, 나이별 결핵 환자 발생률을 보면 60대 이상의 대상자가 60% 이상의 결핵 유병률을 보였으며 특히 80세 이상의 노인결핵 환자가 증가하였다. 다섯째, 성별 결핵 환자발생률 현황은 2010년 대비 2018년에 남성이 여성보다 1.4배가 많은 것으로 나타났다. 여섯째, 전국적으로 결핵 유병률은 전남 1,419명(75.6%)이 가장 높았고, 세종 99명(33.4%)이 가장 낮았다. 일곱째, 국내 외국인 환자 수는 2012년 1,510명으로 지속적으로 늘어나 2016년에는 2,569명으로 증가한 것으로 나타났다. 이상의 결과에 따라 결핵 재발자, 고등학생, 60세 이상의 연령층, 80세 이상의 노인, 군대 등의 남성 집단, 외국인 대상의 신속하고 정확한 결핵 조기 검진정책과 관리가 필요하다.

• 대한전자공학회:학술대회논문집
• /
• 대한전자공학회 2004년도 학술대회지
• /
• pp.717-722
• /
• 2004

A design was done, and all characteristic of photodetectr of the web pattern type which a standard process of the Bipolar which Si PIN structure was used in this paper, and was used for the current amplifier design was used, and high-speed, was used as receiving optcal area of high altitude, and the module which had a low dark current characteristic was implemented with one chip with a base. Important area decreases an area of Ie at the time of this in order to consider an electrical characteristic and economy than the existing receiving IC, and performance of a product and confidence are got done in incense. First of all, the receiving IC which a spec, pattern of a wafer to he satisfied with the following electrical optical characteristic that produced receiving IC of 5V and structure are determined, and did one-chip is made. On the other hand, the time when AR layer of double is $Si_{3}N_{4}/SiO_{2}=1500/1800$ has an optical reflectivity of less than $10{\%}$ on an incidence optical wavelength of 660 ,and, in case of photo detector which reverse voltage made with 1.8V runs in 1.65V, an error about a change of thickness is very the thickness that can be improved surely. And, as for the optical current characteristic, about 5 times increases had the optical current with 274nA in 55nA when Pc was -27dBm. A BJT process is used, and receiving IC running electricity suitable for low voltage and an optical characteristic in minimum 1.8V with a base with two phases is made with one chip. IC of low voltage operates in 1.8V and 3.0V at the same time, and optical link receiving IC is going to be implemented

• 한국안전학회지
• /
• 제30권4호
• /
• pp.39-45
• /
• 2015

This paper deals with development of integrity evaluation instrument for the power line surge protective device. A reliable power supply is an essential element in the developed information and communication society by highly advances in IT technology. However, the lightning incidence also increased with the recent extreme weather events. In Korea, in order to protect the electrical system from lightning surge, SPD(Surge Protective Device) has been used for these past 30 years. However, the method of diagnosing the safety of the SPD in the industry is insufficient. In this paper, SPD integrity evaluation system was composed of a variable DC power source unit, voltage-current sensor and the embedded controller. In order to measure V-I characteristics of MOV, 3 type samples were degraded by impulse current generator. After impulse tests, the varistor voltage of all samples and nonlinearity coefficient were decreased. It confirmed the utility of the developed equipment by this experimental test and the reliability of SPD is expected for surge accident prevention when applied to industrial plant.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2010년도 춘계학술대회 논문집
• /
• pp.29-29
• /
• 2010

Surface contamination and leakage current have caused operating problems. A flashover in a substation may result in destruction of an insulator or many others electrical equipment. Engineering plastics have good characteristic (light weight, good productivity and little of void) as compare with epoxy or porcelain insulators. Outdoor insulator must have resistance to contamination. However, it isn't suited to outdoor insulator because it is not hydrophobic. RTV(Room temperature vulcanizing) has a good property of hydrophobic and micro-filler. nano-filler have characteristics of obstructing exothermic reaction. In order to reduce the incidence of insulator flashover and damage, the silicon rubber contained with micro, nano-filler coating on surface of engineering plastics. In this paper, it compares tracking resistance, leakage current of the engineering plastic coated RTV with that of non-coated engineering plastic. And filled-composites performed much better than non-filled composites.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권18호
• /
• pp.7731-7735
• /
• 2014

Colorectal cancer (CRC) is the third most common cause of death due to cancer in the worldwide and the incidence is also increasing in Turkey. Our present aim was to investigate any association between germ-line methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and CRC risk in Turkey. A total of 86 CRC cases and 212 control individuals of the same ethnicity were included in the current study. Peripheral blood-DNA samples were used for genotyping by StripAssay technique, based on the reverse-hybridization principle and real-time PCR methods. Results were compared in Pearson Chi-square and multiple logistic regression models. The MTHFR 677TT (homozygous) genotype was found in 20.9% and the T allele frequency 4.2-fold increased in CRC when compared with the control group.The second SNP MTHFR 1298CC (homozygous) genotype was found in 14.0% and the C allele frequency 1.4-fold elevated in the CRC group. The current data suggest strong associations between both SNPs of germ-line MTHFR 677 C>T and 1298 A>C genotypes and CRC susceptibility in the Turkish population. Now the results need to be confirmed with a larger sample size.

• 한국융합학회논문지
• /
• 제6권5호
• /
• pp.9-14
• /
• 2015

본 논문에서는 유전체 표면을 소형의 패치로 분해한 다음에 각 패치의 유도전류를 구하는 모먼트법(MoM)과 전체 유전체 표면의 입사전파와 반사 및 침투 전파의 합을 구하는 적분방정식을 융합하여 유전물질로 구성된 육면체의 유도전류 분석하였다. 평면파 전자파가 입사될 때 임의모형의 유전체에 유도되는 유도전류는 일반적으로 수치해석방법을 적용하여 계산하는 것이 정확하며 사용한 적분방정식은 5 명의 과학자가 공동으로 제안한 PMCHW 방정식을 사용하였다. MoM에 사용된 패치는 삼각형 패치를 사용하고 기초함수는 광대역 주파수에 사용할 수 있는 Loop-Patch 기초함수를 사용하였다. 제안된 계산방식은 넒은 주파수 범위에서 임의 모형의 유전체에 대해서 적용할 수 있으며 유전체 육면체의 유도전류를 분석하여 제시하였다.

• 한국통신학회논문지
• /
• 제21권10호
• /
• pp.2710-2723
• /
• 1996

2-dimensional scattering problem of electromagnetic waves by a periodic strip grating on a grounded dielectric slab in case of oblique incidence and arbitrary polarization is analyed by the vector Floquet modal expansion method. Solution convergence versus number of Chebyshev polynomial terms representing the unknown strip current density and number of space harmonics is examined, and some numerical results such as variation of power of significant space harmonics(scattered mode) are compared with those obtained by previous method. In particaluar, the relationship between Bragg blazing phonmena and characteristics mode(current) on the srip is discussed in detail.

• 대한핵의학회지
• /
• 제37권6호
• /
• pp.341-354
• /
• 2003

Radioactive iodine therapy using I-131 for hyperthyroidism has been used for more than 50 years, and generally considered safe and devoid of major side effects. Appropriate patient selection criteria and clinical judgement concerning patient preparation should be employed for its optimal use. It has not been possible to resolve the trade-off between efficient definite cure of hyperthyroidism and the high incidence of post-therapy hypothyroidism. The dose of the I-131 needed to maintain euthyroid state remains an area of uncertainity and debate. Early side effects are uncommon and readily managable. Other than the need for long-term monitoring and, in most cases, lifelong thyroid hormone treatment for late adverse consequences of this treatment remains only conjectural. We have reviewed general principles and recent advances in radioiodine treatment for Graves' hyperthyroidism, specially regarding to several controversies.