• 대한전기학회논문지
• /
• 제38권7호
• /
• pp.524-538
• /
• 1989

최근에 들어 마이크로 컴퓨터를 비롯하여 사무 자동화 및 가정 자동화와 관련한 전자기기에 쓰이는 1KVA이하의 소용량 UPS의 수요가 급격히 증가하고 있다. 이와같은 UPS의 응용에서는 UPS의 소형화와 가격 절감이 가장 요구된다. 본 논문에서는 새로운 방식의 직렬 공진형 인버어터와 그의 제어 방법을 제안하였다. 제안한 인버어터는 영전류 스윗칭 방식의 공진형 컨버어터와 고주파 절연 변압기 및 영전류 스윗칭 방식의 싸이클로 콘버어터로 구성되었다. 공진 전류의 평균 크기를 정현적으로 변화시키고 싸이클로 콘버어터를 이용하여 저주파 출력 전압을 발생시킨다. 제안한 인버어터에서는 양방향 전력 전달이 가능하고 절연 변압기의 크기를 대폭 줄이고 가격도 줄일 수 있다. 제안한 제어방법을 simulation과 실험을 통하여 확인하였다.

• 한국조명전기설비학회:학술대회논문집
• /
• 한국조명전기설비학회 2004년도 춘계학술대회 논문집
• /
• pp.353-357
• /
• 2004

This paper presents the result of survey of case study for harmonics in electrical installations of buildings. Recently, many power electronic equipments(power converter, computers, air conditioners electronic ballasts for fluorescent lamps and so on) are used in office buildings, and harmonic current from them influence the other equipments in a distribution line. Notably, voltage distortion or voltage harmonics may approach or exceed is allowable level in power distribution system. Individual electric power consumers and end-users and responsible for reducing current harmonics while companies or utilities are responsible for reducing voltage harmonics at the point of common coupling in distribution system. As for harmonics, which one of the electric power qualities, it becomes important to obtain harmonic voltage/current distribution of the power system precisely because the use of power electronic apparatus in increasing. To suppress harmonics in electrical ins tallations of buildings, one of many methods suggest that resonance frequencies are controlled by modulating the capacities of high-voltage customer's capacitors.

• 한국조명전기설비학회:학술대회논문집
• /
• 한국조명전기설비학회 2003년도 학술대회논문집
• /
• pp.283-288
• /
• 2003

This paper presents the result of survey of case study for Harmonics in electrical Installations of buildings. Recently, many power electronic equipments(power converter, computers, air conditioners electronic ballasts for fluorescent lamps and so on) are used in office buildings, and harmonic current from them influence the other equipments in a distribution line. Notably, voltage distortion or voltage harmonics may approach or exceed is allowable level in power distribution system. Individual electric power consumers and end-users and responsible for reducing current harmonics while companies or utilities are responsible for reducing voltage harmonics at the point of common coupling in distribution system. As for harmonics, which one of the electric power qualities, it becomes important to obtain harmonic voltage/current distribution of the power system precisely because the use of power electronic apparatus in increasing. However, there are some difficulties on evaluating the measured data in comparison with the simulated result. The primary cause was indentitied with the resonance of harmonics form many sources. To suppress harmonics in electrical installations of buildings, one of many methods suggest that resonance frequencies are controlled by modulating the capacities of high-voltage customer's capacitors.

• 신경정신의학
• /
• 제57권2호
• /
• pp.119-132
• /
• 2018

Despite the fact that pharmacotherapy depressive disorders have proven efficacy, a substantial number of patients are resistant to conventional management. As neuroscientific research about pathophysiology of depression have accumulated, repeated transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) have emerged as an important mechanism-based treatment modality. This overview provides a review of therapeutic application of rTMS and tDCS in patients with depression. The clinical and basic studies of rTMS and tDCS in depression were reviewed and integrated using a literature review and interview with experts. rTMS is a noninvasive procedure of a localized pulsed magnetic field to the surface of the head to cause a depolarization of neurons in the brain cortex. tDCS has a mechanism of modulating cortical excitability in a polarity-specific manner without eliciting action potentials. rTMS and tDCS seem promising for treating depression. Although therapeutic parameters and further technical improvement remain to be systematically investigated, rTMS and tDCS would be a safe and effective intervention to treat depression.

• Nutrition Research and Practice
• /
• 제11권5호
• /
• pp.430-434
• /
• 2017

BACKGROUND/OBJECTIVE: Chronic hyperglycemia induces oxidative stress via accumulation of reactive oxygen species (ROS) and contributes to diabetic complications. Hyperglycemia induces mitochondrial superoxide anion production through the increased activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. This study aimed to determine whether fisetin and luteolin treatments suppress the oxidative stress by modulating the expression of sirtuins (SIRTs) and forkhead box O3a (FOXO3a) under hyperglycemic conditions in human monocytes. MATERIALS/METHODS: Human monocytic cells (THP-1) were cultured under osmotic control (14.5 mmol/L mannitol), normoglycemic (NG, 5.5 mmol/L glucose), or hyperglycemic (HG, 20 mmol/L glucose) conditions, in the absence or presence of fisetin and luteolin for 48 h. To determine the effect of fisetin and luteolin treatments on high glucose-induced oxidative stress, western blotting and intracellular staining were performed. RESULTS: Hyperglycemic conditions increased the ROS production, as compared to normoglycemic condition. However, fisetin and luteolin treatments inhibited ROS production under hyperglycemia. To obtain further insight into ROS production in hyperglycemic conditions, evaluation of p47phox expression revealed that fisetin and luteolin treatments inhibited p47phox expression under hyperglycemic conditions. Conversely, the expression levels of SIRT1, SIRT3, SIRT6, and FOXO3a were decreased under high glucose conditions compared to normal glucose conditions, but exposure to fisetin and luteolin induced the expression of SIRT1, SIRT3, SIRT6, and FOXO3a. The above findings suggest that fisetin and luteolin inhibited high glucose-induced ROS production in monocytes through the activation of SIRTs and FOXO3a. CONCLUSIONS: The results of our study supports current researches that state fisetin and luteolin as potential agents for the development of novel strategies for diabetes.

• 대한기계학회논문집A
• /
• 제36권7호
• /
• pp.797-803
• /
• 2012

비례솔레노이드밸브는 코일전류에 비례하는 전자기력을 이용하여 밸브 변위를 연속적으로 가변시키는 밸브이다. 대용량 비례유량제어밸브는 발전소나 화학 플랜트에서 물, 스팀, 가스 등과 같은 공정유체의 대용량 유량제어에 사용되며 공압이나 모터를 이용하는 밸브에 비하여 우수한 응답성능과 소형화의 장점을 가진다. 본 연구에서는 비례제어밸브를 대상으로 밸브의 동적 특성을 식별한 후 목표 성능이 만족되도록 위치제어기의 비례적분이득을 자동으로 조정하는 기능을 설계하였다. 동특성 식별은 릴레이 피드백을 통하여 한계 안정 상태에서의 임계이득과 임계주기로 파악하였으며, 비례적분이득 결정에는 Ziegler-Nichols 방법을 적용하였다. 구현된 기능은 시험을 통하여 성능을 검증하였으며 밸브 작동점과 릴레이 제어기 변수가 자동조정에 미치는 영향을 분석하였다.

• Fisheries and Aquatic Sciences
• /
• 제26권6호
• /
• pp.406-422
• /
• 2023

Sarcopenia is an age-related, progressive skeletal muscle disorder involving the loss of muscle mass and strength. Previous studies have shown that γ-aminobutyric acid (GABA) from fermented oysters aids in regulatory T cells (Tregs) cell expansion and function by enhancing autophagy, and concomitantly mediate muscle regeneration by modulating muscle inflammation and satellite cell function. The fermentation process of oysters not only increases the GABA content but also enhances the content of branched amino acids and free amino acids that aid the level of protein absorption and muscle strength, mass, and repair. In this study, the effect of GABA-enriched fermented sarco oyster extract (FSO) on reduced muscle mass and functions via Treg modulation and enhanced autophagy in aged mice was investigated. Results showed that FSO enhanced the expression of autophagy markers (autophagy-related gene 5 [ATG5] and GABA receptor-associated protein [GABARAP]), forkhead box protein 3 (FoxP3) expression, and levels of anti-inflammatory cytokines (interleukin [IL]-10 and transforming growth factor [TGF]-β) secreted by Tregs while reducing pro-inflammatory cytokine levels (IL-17A and interferon [IFN]-γ). Furthermore, FSO increased the expression of IL-33 and its receptor IL-1 receptor-like 1 (ST2); well-known signaling pathways that increase amphiregulin (Areg) secretion and expression of myogenesis markers (myogenic factor 5, myoblast determination protein 1, and myogenin). Muscle mass and function were also enhanced via FSO. Overall, the current study suggests that FSO increased autophagy, which enhanced Treg accumulation and function, decreased muscle inflammation, and increased satellite cell function for muscle regeneration and therefore could decrease the loss of muscle mass and function with aging.

• The Journal of Korean Physical Therapy
• /
• 제21권4호
• /
• pp.65-71
• /
• 2009

Purpose: Transcranial direct current stimulation (tDCS) is a useful method for modulating the brain activity. This study compared the effect of continuous and interrupted tDCS using the change in the movement related cortical potential. Methods: Thirty healthy participants (male: 18 and female: 12) were assigned randomly to three groups; sham tDCS, continuous tDCS, which the current continuously flowed for 10 minutes, and interrupted tDCS, which the interrupted current flowed for 10 minutes (repetition: 4sec stimulation and 5sec rest) at an intensity of 1mA with anodal polarity. The effect of tDCS on the right primary motor area was measured from the movement related cortical potential (MRCP) before and after the experiment. MRCP consisted of the bereitshaftspotential (BP) and negative slope potential (NS) at Cz and C4. Results: Continuous and interrupted tDCS showed a significant difference in the changes in the BP, NS at Cz and C4 compared to the sham tDCS. However, there was no significant difference between the continuous tDCS and interrupted tDCS. Conclusion: The change in cortical activity by continuous and interrupted tDCS results from an improvement in the MRCP. An interrupted tDCS may be a safe and useful modality for stimulating the cortical region.

• ETRI Journal
• /
• 제27권5호
• /
• pp.473-483
• /
• 2005

In this paper, we propose two LC voltage-controlled oscillators (VCOs) that improve both phase noise and tuning range. With both 1/f induced low-frequency noise and low-frequency thermal noise around DC or around harmonics suppressed significantly by the employment of a current-current negative feedback (CCNF) loop, the phase noise in the CCNF LC VCO has been improved by about 10 dB at 6 MHz offset compared to the conventional LC VCO. The phase noise of the CCNF VCO was measured as -112 dBc/Hz at 6 MHz offset from 5.5 GHz carrier frequency. Also, we present a bandwidth-enhanced LC VCO whose tuning range has been increased about 250 % by connecting the varactor to the bases of the cross-coupled pair. The phase noise of the bandwidth-enhanced LC-tank VCO has been improved by about 6 dB at 6 MHz offset compared to the conventional LC VCO. The phase noise reduction has been achieved because the DC-decoupling capacitor Cc prevents the output common-mode level from modulating the varactor bias point, and the signal power increases in the LC-tank resonator. The bandwidth-enhanced LC VCO represents a 12 % bandwidth and phase noise of -108 dBc/Hz at 6 MHz offset.

• IMMUNE NETWORK
• /
• 제14권4호
• /
• pp.182-186
• /
• 2014

Lymphatic vessels are routes for leukocyte migration and fluid drainage. In addition to their passive roles in migration of leukocytes, increasing evidence indicates their active roles in immune regulation. Tissue inflammation rapidly induces lymphatic endothelial cell proliferation and chemokine production, thereby resulting in lymphangiogenesis. Furthermore, lymphatic endothelial cells induce T cell tolerance through various mechanisms. In this review, we focus on the current knowledge on how inflammatory cytokines affect lymphangiogenesis and the roles of lymphatic vessels in modulating immune responses.