• 제목/요약/키워드: Cumulative effects

검색결과 590건 처리시간 0.308초

Effects of titanium oxide nanoparticles on Oryzias latipes embryos and sac-fry under different irradiation conditions

  • Nam, Sun-Hwa;Shin, Yu-Jin;An, Youn-Joo
    • Environmental Engineering Research
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    • 제22권4호
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    • pp.426-431
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    • 2017
  • Some phototoxicity of titanium dioxide nanoparticles ($TiO_2$ NPs) has been reported in recent years in studies with fish embryos or larvae. However, it is necessary to focus on the potential effects of embryonic exposure due to irreversible abnormalities and mortalities observed in sac-fry, and to expand various fish embryos to generate multiple test species. The aim of this study was to evaluate the effects of $TiO_2$ NPs under different irradiation conditions in exposed Oryzias latipes (O. latipes) at the embryonic and sac-fry stages. The effects of different irradiation conditions were observed using ultra-violet (UV) and visible light, and the corresponding effects were monitored by determining cumulative mortality and abnormality. O. latipes were exposed for 8 d to 0, 1, 5, 10, or 50 mg/L $TiO_2$ NPs under UV ($4,818.86mW/m^2$ at the bottom of clear vials) or visible light, after which the embryos were transferred to NP-free embryo-rearing solution until 16 days post fertilization (dpf). Abnormalities of embryos and sac-fry increased at high $TiO_2$ NP concentrations under UV irradiation, compared to control samples treated with visible light or UV irradiation alone. This work provides information regarding the phototoxicity of $TiO_2$ NPs using O. latipes at the embryonic and sac-fry stages.

와인 선택 속성에 대한 관능적 태도와 와인 정보원의 영향 및 상호관계 (Effects and Interrelationship on Sensual Behavior and Wine Information Sources in Selection Attributes of Wine)

  • 강근옥
    • 동아시아식생활학회지
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    • 제24권4호
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    • pp.457-464
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    • 2014
  • This study investigated the effects and interrelationship on sensual behavior and wine information sources in selection attributes of wine. Selection attributes of wine were categorized into four variables: sensual behavior, recommend information, label information, and wine information. The study showed that for sensual behavior variable, "taste" was the most influential item as compared to "food harmony", "mood harmony" and "partner's choice". For recommendation information, label information and wine information, "specialist", "grape varieties" and "brand" had the most significant effects. The study performed factor analysis on sensual behavior and wine information sources. The cumulative variance was 74.197%, implying that all four variables incorporated appropriate items. In the reliability analysis, all four variables showed Cronbach's ${\alpha}$ values above 0.6. In the analysis of the causal relations using a structural model, the effects of customers' sensual behavior on wine information sources was further investigated. The model verified that taste, food harmony, mood harmony and partner's choice, which are items of sensual behavior, had significant impacts when choosing wine. Sensual behavior influenced all wine information sources, which customers utilize in decision-making. Among these sources, sensual behavior had the biggest effects on recommendation information, followed by wine information and label information.

Seismic performance of RC short columns with light transverse reinforcement

  • Tran, Cao Thanh Ngoc;Li, Bing
    • Structural Engineering and Mechanics
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    • 제67권1호
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    • pp.93-104
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    • 2018
  • The seismic behavior of reinforced concrete (RC) short columns with limited transverse reinforcement is investigated in this paper through an experimental program. The experimental program consists of four small-scale RC columns with an aspect ratio of 1.7, which are tested to the axial failure stage. The cracking patterns, hysteretic responses, strains in reinforcing bars, displacement decomposition and cumulative energy dissipation of the tested specimens are reported in detail in the paper. The effects of column axial load are investigated to determine how this variable might influence the performance of the short columns with limited transverse reinforcement. Brittle shear failure was observed in all tested specimens. Beneficial and detrimental effects on the shear strength and drift ratio at axial failure of the test specimens due to the column axial load are found in the experimental program, respectively.

파로설계에 관한 소고 (A Study on the Design against Metal Fatigue)

  • 이순복
    • 한국기계연구소 소보
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    • 제4권1호
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    • pp.19-26
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    • 1981
  • Fatigue, the birth and growth of cracks in metal parts subjected to repeated loading, has been a problem plaguing engineers since the Industrial Revolution and the advent of rotating or reciprocating machinery. Designing against metal fatigue was studied briefly in several aspects. Examples of fatigue failures were shown. Fatigue was classified by loading: uniaxial Fatigue, multiaxial fatigue, cumulative fatigue da¬mage. Fatigue design criteria were discussed: Infinite-Life Design, Safe-Life Design, Fail-Safe Design, and Damage Tolerant Design. Mitigation of notch effects by design, improvement of fatigue strength of metal parts by residual stress and surface finishing were discussed. Relative fatigue beha¬vior was studied under various environmantal conditions. Especially the effects of corrosion, temperature, fretting, and irradiation were covered.

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전완(前腕)의 국부(局部) 진동(振動)이 작업자의 굴근(屈筋) 및 신근(伸筋) 피로(疲勞)에 미치는 영향 (The Effects of Hand-Arm Vibration on Flexor and Extensor Fatigue)

  • 이동춘;김길주
    • 대한인간공학회지
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    • 제18권1호
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    • pp.55-69
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    • 1999
  • It is very common to use the powered hand tools to enhance the productivity in various types of industry. But the use of the powered hand tools could cause health problems such as cumulative trauma disorders and vibration white fingers. In this study. the effects of hand-arm vibration and anatomical hand position on localized muscle fatigue were analyzed. Eight healthy male subjects volunteered for the study. Vibration frequencies of 0, 40, 80, 100, 150, and 200Hz and hand position of flexion and ulnar deviation were selected for the independent variables of the experiment. Median frequency shifting was used as a dependent variable. The results indicated that at the vibration frequency of 40Hz and accelation of 2g, the muscle fatigue was the greatest. For the hand position. there was significant difference between neutral and flexion. and neutral and ulnar deviation, but no difference between flexion and ulnar deviation. These results could be applied in designing powered hand tools to minimize the health problems.

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ASME BPVC Section XI Appendix L의 결함허용평가에 따른 허용운전주기 민감도 분석 (Sensitivity Analysis for Allowable Operating Period Based on the Flaw Tolerance Evaluation of ASME BPVC Section XI Appendix L)

  • 오창식;조두호;정명조
    • 한국압력기기공학회 논문집
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    • 제17권2호
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    • pp.126-136
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    • 2021
  • During operation of nuclear power plants, the fatigue assessment should be conducted repeatedly, considering changes of operating environments. For the case that cumulative usage factors (CUFs) may exceed the acceptance limit, flaw tolerance evaluation can be an alternative method to meet the regulatory requirements. In this respect, this paper analyzes the effects of the input variables for flaw tolerance evaluation based on ASME BPVC Section XI Appendix L. The reference analysis is performed for the example problem in NUREG/CR-6934. Then effects of the crack orientation, stress intensity factor solutions, thermal stress profiles, fatigue stress decomposition and fatigue crack growth curves are considered for the sensitivity analysis. The results show that the stress analysis considering the actual environment plays a crucial role in flaw tolerance evaluation.

욕창예방을 위한 체위변경 중재 효과의 비교순위: 네트워크 메타분석 (Comparative Effects and Ranks of Repositioning for Pressure Ulcer Prevention in Adults: A Network Meta-analysis)

  • 고지운
    • 근관절건강학회지
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    • 제29권1호
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    • pp.18-27
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    • 2022
  • Purpose: A network meta-analysis was conducted to assess the comparative effects and ranks of repositioning for pressure ulcer prevention in adults. Methods: A network meta-analysis was performed in a frequency method, using the "netmeta" package of R software version 4.1. The effects of repositioning intervention were confirmed by the odds ratio. The comparative ranking of the repositioning effects was confirmed using the cumulative probability (P-score). Results: Seven intervention studies were included in this study. Based on the P-score, the use of the repositioning system was ranked as the most effective among all interventions (P-score 78.7%). Next was 3~4-hour repositioning combined with memory foam mattress use (P-score 77.2%), use of wearable sensor (P-Score 61.4%), 2-hour repositioning combined with memory foam mattress use (P-score 59.1%), 2-hour repositioning combined with powered air pressure redistribution mattress use (P-score 18.0%), and 4-hour repositioning combined with powered air pressure redistribution mattress use (P-score 18.0%). Conclusion: This study provides information on the relative comparative value of various repositioning interventions to prevent pressure ulcers using network meta-analysis. This is expected to be useful for nurses' decision-making when applying repositioning interventions in clinical practice

패널자료를 활용한 대학생 중도탈락 결정요인 분석 (The Student Determinants of College Non-completion)

  • 황상현;이진영
    • 아태비즈니스연구
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    • 제13권3호
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    • pp.361-373
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    • 2022
  • Purpose - This paper analyzes the student determinants of college non-completion and estimates the effects of each determinant on college non-completion. Design/methodology/approach - We use student panel data from a large Korean university from 2011 to 2021. Our results are from estimation of fixed-effects logit model. Findings - The results show that grade point average, participation in extracurricular activities, the number of counseling sessions with teachers, and financial aid are the main determinants of college non-completion. Academic probation, which is defined as any person who has a cumulative grade point average below a one point seven five, increases the non-completion rate by 2.6 percentage points and an one-point rise in extracurricular activities index reduces the rate by 0.1 percentage points. The effects of each determinant are heterogeneous across student sub-groups which are separated by gender, nationality, and academic discipline. Research implications or Originality - Tailored support programs for academically discouraged students that incorporate student characteristics and backgrounds are necessary to increase college completion rates and degree attainment.

Rat적출심방 운동성에 대한 Prostaglandin $F_2$ alpha와 Ouabain작용의 비교 (Comparative Effects of Prostaglandin $F_2$ alpha and Ouabain on the Isolated Rat Atria)

  • 이광윤
    • 대한약리학회지
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    • 제20권1호
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    • pp.55-65
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    • 1984
  • [$PGF_{2{\alpha}}$]의 rat적출심방에 대한 작용을 ouabain의 작용과 비교하여 다음과 같은 결과를 얻었다. $PGF_{2{\alpha}}$의 양성변력성작용은 ouabain의 작용에 비해 potency가 강하고 efficacy는 낮았다. Ouabain은 $PGF_{2{\alpha}}$의 양성변시성작용과 유사한 양성변시성 경향을 나타내었는데 이 점에 대해 추후의 탐구가 요구된다. $PGF_{2{\alpha}}(3{\pm}10^{-8}M)$의 작용은 저칼슘농도(1.4mM)에서 ouabain$(3{\pm}10^{-3}M)$보다 현저히 $({\leq}0.05{\sim}p{\leq}0.00)$강하게 나타났고, medium내에 첨가되는 $Ca^{++}$에 대하여도 보다 예민하게 반응하였다. 저칼륨 medium(2.8mM) 또는 medium내 $K^+$첨가는 $PGF_{2{\alpha}}$보다 ouabain의 작용에 더 큰 영향을 미쳤다. $PGF_{2{\alpha}}$와 ouabain의 작용에 미치는 lidocaine ($1{\pm}10^{-5}M$이상의 고농도)의 영향은 매우 흡사하여 별다른 차이점을 볼 수 없었다. Propranolol $(3{\pm}10^{-6}M)$로써 전처치하여 아드레나린성 ${\beta}$수용체를 봉쇄한 적출심방에서 $PGF_{2{\alpha}}$ 양성변력성 및 양성변시성 작용은 방해를 받지 않았다. 이상의 결과로 보아 $PGF_{2{\alpha}}$는 ouabain의 $Na^+$, $K^+$-ATPase 억제기전파는 달리 $PGF_{2{\alpha}}$ 고유의 막수용체에 작용하여 $Ca^{++}$의 세포내 유입을 촉진시키는 기전으로 작용하는 것으로 추측되며, 그 수용체의 등정(identification)은 추후의 연구과제로 남는다.

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기업합병의 성과에 영향을 주는 요인에 대한 실증적 연구 (The Gains To Bidding Firms' Stock Returns From Merger)

  • 김용갑
    • 경영과정보연구
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    • 제23권
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    • pp.41-74
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    • 2007
  • In Korea, corporate merger activities were activated since 1980, and nowadays(particuarly since 1986) the changes in domestic and international economic circumstances have made corporate managers have strong interests in merger. Korea and America have different business environments and it is easily conceivable that there exists many differences in motives, methods, and effects of mergers between the two countries. According to recent studies on takeover bids in America, takeover bids have information effects, tax implications, and co-insurance effects, and the form of payment(cash versus securities), the relative size of target and bidder, the leverage effect, Tobin's q, number of bidders(single versus multiple bidder), the time period (before 1968, 1968-1980, 1981 and later), and the target firm reaction (hostile versus friendly) are important determinants of the magnitude of takeover gains and their distribution between targets and bidders at the announcement of takeover bids. This study examines the theory of takeover bids, the status quo and problems of merger in Korea, and then investigates how the announcement of merger are reflected in common stock returns of bidding firms, finally explores empirically the factors influencing abnormal returns of bidding firms' stock price. The hypotheses of this study are as follows ; Shareholders of bidding firms benefit from mergers. And common stock returns of bidding firms at the announcement of takeover bids, shows significant differences according to the condition of the ratio of target size relative to bidding firm, whether the target being a member of the conglomerate to which bidding firm belongs, whether the target being a listed company, the time period(before 1986, 1986, and later), the number of bidding firm's stock in exchange for a stock of the target, whether the merger being a horizontal and vertical merger or a conglomerate merger, and the ratios of debt to equity capital of target and bidding firm. The data analyzed in this study were drawn from public announcements of proposals to acquire a target firm by means of merger. The sample contains all bidding firms which were listed in the stock market and also engaged in successful mergers in the period 1980 through 1992 for which there are daily stock returns. A merger bid was considered successful if it resulted in a completed merger and the target firm disappeared as a separate entity. The final sample contains 113 acquiring firms. The research hypotheses examined in this study are tested by applying an event-type methodology similar to that described in Dodd and Warner. The ordinary-least-squares coefficients of the market-model regression were estimated over the period t=-135 to t=-16 relative to the date of the proposal's initial announcement, t=0. Daily abnormal common stock returns were calculated for each firm i over the interval t=-15 to t=+15. A daily average abnormal return(AR) for each day t was computed. Average cumulative abnormal returns($CART_{T_1,T_2}$) were also derived by summing the $AR_t's$ over various intervals. The expected values of $AR_t$ and $CART_{T_1,T_2}$ are zero in the absence of abnormal performance. The test statistics of $AR_t$ and $CAR_{T_1,T_2}$ are based on the average standardized abnormal return($ASAR_t$) and the average standardized cumulative abnormal return ($ASCAR_{T_1,T_2}$), respectively. Assuming that the individual abnormal returns are normal and independent across t and across securities, the statistics $Z_t$ and $Z_{T_1,T_2}$ which follow a unit-normal distribution(Dodd and Warner), are used to test the hypotheses that the average standardized abnormal returns and the average cumulative standardized abnormal returns equal zero.

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