• Title/Summary/Keyword: Cu status

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Development Status of Electrolytic Copper Foil for Fine Pitch PCB (협피치화 대응을 위한 전해동박의 개발 현황)

  • Jeon, Sang-Hyeon
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2012.05a
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    • pp.134-134
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    • 2012
  • 패키징용 PCB를 비롯한 대부분의 PCB는 동박을 소재로 사용하게 된다. 패키징용 PCB를 중심으로 한 PCB의 협피치화에 대응하기 위해서 전해동박의 저조도화, 박형화에 대한 필요성이 증대되고 있다. 동박의 제조공정은 드럼상에 Cu를 도금하는 공정(EM 공정), 표면에 조도를 부여하고 내열, 방청성 등을 부여하는 공정(TM공정), 절단하는 공정(SM공정)으로 이루어진다. 동박의 저조도화를 위해서는 EM 및 TM공정의 첨가제 개발 및 저조도 도금 공정 개발이 필요하다. 박형화를 위해서는 얇은 두께에서도 핸들링이 가능하도록 동박의 강도를 높이거나 제조공정을 개선하는 연구가 필요하다. 본 발표에서는 이러한 전해동박의 제조공정을 소개하고 협피치화 대응을 비롯한 전해동박의 개발 방향에 대해서 소개하고자 한다.

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Effects of Cell Status of Bovine Oviduct Epithelial Cell (BOEC) on the Development of Bovine IVM/IVF Embryos and Gene Expression in the BOEC Used or Not Used for the Embryo Culture

  • Jang, H.Y.;Jung, Y.S.;Cheong, H.T.;Kim, J.T.;Park, C.K.;Kong, H.S.;Lee, H.K.;Yang, B.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.7
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    • pp.980-987
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    • 2008
  • The objective of this study was to investigate the effects of cell status of BOEC on development of bovine IVM/IVF embryos and gene expression in BOEC before or after culturing of embryos. The developmental rates beyond morula stage in the BOEC co-culture group was significantly higher than in the control group (p<0.05). In particular, blastocyst production in the BOEC co-culture group (28.3%) was dramatically increased compared with the control group (7.2%). In the in vitro development of bovine IVM/IVF embryos according to cell status, the developmental rates beyond morula stage in the primary culture cell (PCC) co-culture group were the highest of all experimental groups. Expression of genes related to growth (TGF-${\beta}$ EGF and IGFBP), apoptosis (Bax, Caspase-3 and p53) and antioxidation (CuZnSOD, MnSOD, Catalase and GPx) in different status cells of BOEC for embryo culture was detected by RT-PCR. While EGF gene was detected in isolated fresh cells (IFC) and PCC, TGF-${\beta}$ and IGFBP were found in IFC or PCC after use in the embryo culture, respectively. Caspase-3 and Bax genes were detected in all experimental groups regardless of whether the BOEC was used or not used in the embryo culture. However, p53 gene was found in IFC of both conditions for embryo culture and in frozen/thawed culture cells (FPCC) after use in the embryo culture. Although antioxidant genes examined were detected in all experimental groups before using for the embryo culture, these genes were not detected after use. This study indicated that the BOEC co-culture system used for in vitro culture of bovine IVF embryos can increase the developmental rates, and cell generations and status of BOEC might affect the in vitro development of bovine embryos. The BOEC monolayer used in the embryo culture did not express the growth factors (TGF-${\beta}$ and EGF) and enzymatic antioxidant genes, thereby improving embryo development in vitro.

Study on minerals status of dairy cows and their supplementation through area specific mineral mixture in the state of Jharkhand

  • Bhanderi, B.M.;Goswami, Ajay;Garg, M.R.;Samanta, Saikat
    • Journal of Animal Science and Technology
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    • v.58 no.12
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    • pp.42.1-42.8
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    • 2016
  • Background: Deficiency of macro and micro-minerals in the ration of dairy cows adversely affects growth, milk production and reproduction efficiency. It is essential to examine mineral concentrations in feeds offered to dairy cows in practical farms. Methods: Two villages from each taluka were selected at random for taking representative samples of feeds, forages and hair. Within the village, help was sought from village milk producers and district animal husbandry officer for identification of 4 to 5 farmers and collection of representative samples. All the samples were processed and analyzed for chemical composition as well as major macro and micro-minerals, using Inductively Coupled Plasma-Optical Emission Spectrometer. Results: Ca content in wheat straw (0.29%), crushed maize (0.02%) and wheat bran (0.12%) was found to be below the critical level (0.30%). The P content in concentrate ingredients was high (0.26-0.96%), but low in dry roughages (0.06-0.12%). Cereal straws (0.14%) and grains (0.12%) were deficient in Mg. Feeds and forages were found to be adequate in K (1.50%). Cereals straws were found to be deficient in S (0.11%). Greens were good source of Cu (12.02 ppm). Wheat straw was found to be low in Zn (18 ppm), but high in Mn (225 ppm) and Fe (509 ppm). Local grasses and azolla green were found to be rich source of Co (>1.00 ppm). Se (0.63 ppm) was present in appreciable quantities in most of the feedstuffs. Conclusions: From the present study, it was apparent that the feeds and forages available in the state of Jharkhand may not meet the requirements for Ca, P, Mg, Cu, Zn and Co in order to sustain a milk production of ~10 kg/day. Therefore, it is necessary to supplement these deficient minerals through area specific mineral mixture in the ration of dairy cows for improving productivity and reproduction efficiency.

Superoxide Dismutase Isoenzyme Activities in Plasma and Tissues of Iraqi Patients with Breast Cancer

  • Hasan, Hathama Razooki;Mathkor, Thikra Hasan;Al-Habal, Mohammed Hasan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2571-2576
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    • 2012
  • Breast cancer is the first of the most common ten cancers in Iraq. Its etiology is multifactorial, oxidative stress and lipid peroxidation being suggested to play important roles in carcinogenesis. The purpose of this study was to investigate the oxidant-antioxidant status in breast cancer patients, by measuring SOD isoenzyme activities (total SOD, CuZn-SOD, Mn-SOD and EC-SOD) in plasma and breast tumors, and by estimating thiobarbituric reactive substances (TBRS) in tissue homogenates. General increase in total SOD activity was observed in plasma and tissue samples of breast tumors, greater in the malignant when compared to benign group (p<0.05). Mn-SOD showed a significant decrease in tissue malignant samples (p<0.05), and insignificant decrease in plasma malignant samples compared with control and benign samples. Plasma EC-SOD activity in both patient benign and malignant breast tumors demonstrated 3.5% and 22.8% increase, respectively. However, there was a decrease in tissue EC-SOD activity in malignant breast tumors when compared with benign. A similar tendency was noted for TBRS. We suggest that elevated total SOD might reflect a response to oxidative stress, and then may predict a state of excess reactive oxygen species in the carcinogenesis process. If there is proteolytic removal of the heparin binding domain, EC-SOD will lose its affinity for the extracellular matrix and diffuse out of the tissue. This will result in a decreased EC-SOD activity, thus leading to an increase in the steady-state concentration of $O^{2-}$ in this domain, and increase in EC-SOD activity in the extracellular fluid. This might explain the results recorded here concerning the decrease in tissue EC-SOD activity and increase in plasma of breast cancer patients.

Studies on Heavy Metal Contamination of Agricultural Products, Soils and Irrigation Waters in Abandoned Mines (폐광산지역 농산물, 토양 및 농경수의 중금속오염에 관한 연구)

  • 김미혜;소유섭;김은정;정소영;홍무기
    • Journal of Food Hygiene and Safety
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    • v.17 no.4
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    • pp.178-182
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    • 2002
  • This study was conducted to estimate the status of heavy metal contamination in agricultural products (n = 280), soils (n = 280), and irrigation waters (n = 48) in abandoned mines & normal farm lands (n = 8). The samples were digested with acids, then analyzed fur the contents of lead (Pb), cadmium (Cd), copper (Cu), mercury (Hg), arsenic (As) and chrome (Cr) by an inductively coupled plasma spectrometer (ICP) and graphite- atomic absorption spectrophotometer (AAS). The contents of Hg were determined using a mercury analyzer. Abandoned mines had soils with higher contents of heavy metals except Cr and irrigation waters with higher heavy metals except Hg, compared to those of normal farmlands. The contents of heavy metals in agriculture products varied depending types of products. Agricultural products in abandoned mines generally showed with higher contents of heavy metals except Cu, compared to those of normal farmlands. There was no significant relationship in heavy metal contents between agricultural products and soils (p > 0.05). It is suggested that heavy metals of agricultural products and soils in abandoned mines should be continuously monitored.

Changes of Nutrient Content of Circulating Solution in Three Different New Hydroponics for Oriental Melons(Cucumis melo L. var. makuwa Mak.) (참외용 수경재배시스템에서의 순환배양액의 무기이온 함량의 변화)

  • 조익환;전하준
    • Journal of Bio-Environment Control
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    • v.11 no.4
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    • pp.168-174
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    • 2002
  • A new circulating hydroponic system was invented for oriental melons grown in the greenhouse. For developing nutrient solution management techniques, we examined the changes of nutrient contents of circulating solution in three different types of new hydroponic systems. The yield and fruit quality of oriental melons in Hydroponics were better than those in soil culture. The substrate culture was appropriate fer hydroponics of oriental melons, and NFT was turned to be the opposite due to the physiological disorder during hot seasons. Yamazaki's melon solution with EC 2.0dS.m$^{[-10]}$ was the most appropriate for oriental melons. The new circulating hydroponic system seemed to be appropriate for oriental melons because of the stable EC, pH and the macro- and micro-element contents. NO$_3$-N, Ca and Mg contents in the circulating solution kept a good balance in all types of hydroponics. However, p content, compared to other types, decreased by the degree of 1 me.L$^{[-10]}$ in perlite medium. K content showed irregular status in perlite but showed the stable status in cocopeat. Generally, microelements, except Mo, showed stable absorption in the substrate culture. However, in NET, most of the elements showed irregular absorption except B and Mn. Microelement absorption, especially Cu, Zn and Mo, decreased during hot seasons.

Distributions of Organic Matter and Heavy Metals in the Surface Sediment of Jaran Bay, Korea (자란만 표층 퇴적물 중 유기물과 중금속 농도분포)

  • Hwang, Hyunjin;Hwang, Dong-Woon;Lee, Garam;Kim, Hyung-Chul;Kwon, Jung-No
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.1
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    • pp.78-91
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    • 2018
  • In order to understand the distributions of organic matter and heavy metal concentrations in the surface sediment of Jaran Bay, we measured the grain size, total organic carbon (TOC), total nitrogen (TN), and heavy metals (As, Cd, Cr, Cu, Fe, Hg, Mn, Pb, and Zn) in surface sediments collected at 15 stations in this bay in November 2014. The sediment consisted of finer sediment such as mud and clay, with 8.6-9.8Ø($9.3{\pm}0.3$Ø) of mean grain size. The concentrations of TOC and TN in the sediment ranged from 1.51-2.39 % ($1.74{\pm}0.22%$) and 0.20-0.33 % ($0.23{\pm}0.03%$), respectively, and did not show spatial difference. The carbon to nitrogen ratio (C/N ratio) ranged from 5-10, indicating that organic matter in the sediment originated from oceanic sources such as animal by-products from fish and shellfish farms. The concentrations of Cr, Fe, and Mn were much higher in the mouth of the bay than in the inner bay, and the concentrations of As, Cd, Cu, Hg, Pb, and Zn showed an opposite distribution pattern. Based on the results of the sediment quality guidelines (SQGs), enrichment factor (EF), geoaccumulation index ($I_{geo}$), pollutant load index (PLI), and ecological risk index (ERI), the surface sediment in Jaran Bay is not polluted or only slightly polluted with Cd, Cr, Cu, Hg, Pb, and Zn, whereas it is moderately to strongly polluted with As. In particular, some regions in the bay were identified as having a considerable risk status, indicating that metal concentration in the sediment could impact benthic organisms. Thus, the systematic management for marine and land sources of organic matter and heavy metals around Jaran Bay is necessary in order to ensure seafood safety and maintain sustainable production on shellfish farms.

Determination of Hazardous Metals in Nail Enamel Containing Glitter (글리터를 포함한 네일 에나멜 제품의 유해 금속 분석)

  • Ko, Suk Kyung;Chung, Sam Ju;Park, Young Hye;Park, Ae Sook;Kim, Hyun Jung;Park, Geon Yong;Oh, Young Hee
    • Journal of Environmental Health Sciences
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    • v.43 no.2
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    • pp.103-110
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    • 2017
  • Objectives: This study was performed to provide basic data for the re-establishment of standards (criteria) and analytical methods for hazardous metals in nail enamel. Methods: Ten metals (lead; Pb, arsenic; As, cadminum; Cd, antimony: Sb, cobalt; Co, nikel; Ni, copper; Cu, chromium; Cr, aluminum; Al, and mercury; Hg) were measured in 67 commercial nail enamels containing glitter and/or pearls. The content of hazardous metals (excepting Hg) was determined by using an inductively coupled plasma-optical emission spectrophotometer (ICP-OES) after microwave digestion. Mercury content was measured by a mercury analyzer without any preparation. Results: The detected ranges of the intact samples were as follows: $ND-1.756{\mu}g/g$ for Pb, $ND-1.24{\mu}g/g$ for As, ND for Cd, $ND-20.41{\mu}g/g$ for Sb, $ND-12.36{\mu}g/g$ for Co, $ND-7.908{\mu}g/g$ for Ni, $0.088-79.27{\mu}g/g$ for Cu, $0.281-18.54{\mu}g/g$ for Cr, $13.78-3563{\mu}g/g$ for Al, and $ND-0.044{\mu}g/g$ for Hg. After centrifugation, the detected ranges of supernatant were as follows: $ND-0.435{\mu}g/g$ for Pb, $ND-0.504{\mu}g/g$ for As, ND for Cd, $ND-0.035{\mu}g/g$ for Sb, $ND-13.17{\mu}g/g$ for Co, $ND-0.232{\mu}g/g$ for Ni, $0.117-90.07{\mu}g/g$ for Cu, $0.174-2.787{\mu}g/g$ for Cr, and $9.459-1565{\mu}g/g$ for Al. The results of this analysis showed that the levels of heavy metals such as Pb, As, and Sb were much higher in the intact samples than those of supernatant. Conclusion: In the present study, we found that the levels of hazardous metals were significantly different depending on the status of the presence of glitter. Based on the results, we recommend that the product consumer refrain from prolonged application of nail enamel, avoid biting or chewing the nails, and wear gloves during cooking and washing dishes.

Iron Intake During Pregnancy on Serum Concentrations of Trace Minerals in Mothers and Neonates (임신기간 중 철 섭취가 모체와 제대 혈청의 미량 무기질 농도에 미치는 영향)

  • Kim, Hye-Ra;Lim, Hyeon-Sook
    • Journal of Nutrition and Health
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    • v.41 no.3
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    • pp.242-253
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    • 2008
  • It is a common clinical practice to recommend taking iron supplements for pregnant women during gestation. Although it is required to ensure adequate iron stores during pregnancy, there has been some debate over the interference effects of excessive iron load, because it is possible to compete in the transport in the intestine and placenta and in binding to serum proteins of other trace minerals. In this study, maternal and neonatal serum concentrations of Fe, Zn, Cu, Se, Cr, Mn, and Co were assessed along with maternal Fe intakes. A total of 124 pregnant women and their term neonates participated voluntarily in this research. The women were divided into one of the three groups {high Fe intake (HFI), median Fe intake (MFI), and low Fe intake (LFI)} by their total Fe intakes and one of the two groups (Anemic and Normal) by their Fe nutritional status. All the data were compared among the three groups and between the two groups also. Total Fe intakes of HFI, MFI, and LFI groups were 140.8 ${\pm}$ 76.1, 68.0 ${\pm}$ 11.2, and 30.2 ${\pm}$ 8.6 mg/day, respectively. Those of Anemic and Normal groups were 90.1 ${\pm}$ 74.8 and 86.6 ${\pm}$ 46.8 mg/day, respectively. Maternal Hb concentration and Hct were not significantly different among HFI, MFI, and LFI groups but those were significantly different between Anemic and Normal groups. However, neonatal Hb concentration was not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups either. Maternal serum Fe concentrations of the three groups, HFI, MFI, and LFI, were similar but that of Anemic group was significantly lower compared to Normal group. However, there was no significant difference in neonatal serum Fe concentrations among the three groups and between the two groups either. Serum concentrations of the other trace minerals in both mothers and neonates were not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups. In addition, in the maternal serum, Fe concentration was positively correlated to Zn and Se concentration, respectively. As for the neonatal serum, Fe concentration showed a positive correlation to Zn, Cu, Mn, Se, and Co concentration, respectively. No trace mineral concentration was found to correlate negatively to Fe concentration in both maternal and neonatal serum, The results in this study indicate that Fe intakes of pregnant women, even if it is considerably above the level of estimated average requirement (EAR), may not affect serum Fe concentration in both mothers and neonates. In addition it might not influence adversely on the availability of other trace minerals including Zn and Cu in both mothers and neonates.

Assessment of Heavy Metals Contamination in Children's Playground Soil in Seoul (서울시 어린이놀이터 토양의 중금속 오염 평가)

  • So Young Park;Won Hyun Ji
    • Journal of Environmental Impact Assessment
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    • v.32 no.5
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    • pp.269-278
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    • 2023
  • The pollution status of heavy metals in the soils of children's playground was investigated for a sustainable soil environment in urban parks of Seoul. As sampling sites, 281 locations were selected from a 7 districts in the Seoul city. The overall mean concentrations of the heavy metals (Cd 0.21 mg/kg, Cu 5.97 mg/kg, As 2.40 mg/kg, Pb 7.55 mg/kg, Zn 34.08 mg/kg, Ni 4.22 mg/kg, Hg 0.02 mg/kg and Cr6+ not detected.) in the soils of the palygrounds were lower than the worrisome level in criteria for area 1 in Korea soil environment conservation act. In addition, when the soil pollution grade (SPC) was evaluated as an average value, it was found to be less than 100, the first grade, at all points in the seven autonomous districts, indicating thatthe soil was in good soil condition. However, when evaluated as the maximum value, some of the five districts showed values of 100 or more. Therefore, it was found that continuous management and interest of the local government, which is the management body of children's playgrounds, is necessary for a safe soil environment.