• Title/Summary/Keyword: Cs domain

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Response Characteristics of Forced Vibration of High Damping Vehicle Passing the Bumped Barrier (둔턱을 진행하는 고감쇠 차량의 강제진동 응답특성)

  • Kim, Jong-Do;Yoon, Moon-Chul
    • Journal of Convergence for Information Technology
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    • v.11 no.3
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    • pp.132-139
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    • 2021
  • The response characteristics of the forced vibration generated when the high-damped vehicle pass the bumped barrier was studied, and in particular, the response behavior of displacement, velocity and acceleration was analyzed for the forced vibration model. In addition, in order to obtain responses such as displacement, velocity, and acceleration, a numerical analysis technique of the Runge-Kutta-Gill method was performed in time domain. The response was successfully obtained in detail under several high damping conditions. As a numerical analysis result, the response of the vehicle was obtained by considering the vehicle body to which the impulse impact was applied. Also, the analysis result was compared with the experimental result in order to verify the validity of vehicle model. The amplitude and natural frequency of the vehicle were considered and analyzed. The Nyquist diagram of the vehicle model was also obtained and the relationship could be analyzed. And the vibration response was analyzed on different mass, damping and stiffness.

FRF Analysis of a Vehicle Passing the Bump Barrier (둔턱 진행 차량의 주파수응답 분석)

  • Kim, Jong-Do;Yoon, Moon-Chul
    • Journal of Convergence for Information Technology
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    • v.12 no.3
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    • pp.151-157
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    • 2022
  • The purpose of this study was to investigate the frequency characteristics of forced vibration considering the vehicle progress. And the vibration characteristics in frequency domain that occur, when vehicle passes the bump, were analyzed. The responses such as displacement, velocity and acceleration were obtained through numerical analysis, and FFT processing was performed to analyze the frequency response function(FRF) characteristics. In particular, the location of vehicle eigenmodes and external excitation modes was clearly shown and analyzed. In the forced vibration model by external force, the behavior of the eigenmode in power spectrum and real and imaginary parts were also analyzed. The mode characteristics were also analyzed in each FRF. It was approximated by assuming total excitation force by considering the exciting frequency using impulse and sine wave forces, which can give the amplitude and frequencies. The response characteristics of forced oscillations having different mass, damping and stiffness have been systematically discussed.

Genome-wide identification of histone lysine methyltransferases and their implications in the epigenetic regulation of eggshell formation-related genes in a trematode parasite Clonorchis sinensis

  • Min-Ji Park;Woon-Mok Sohn;Young-An Bae
    • Parasites, Hosts and Diseases
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    • v.62 no.1
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    • pp.98-116
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    • 2024
  • Epigenetic writers including DNA and histone lysine methyltransferases (DNMT and HKMT, respectively) play an initiative role in the differentiation and development of eukaryotic organisms through the spatiotemporal regulation of functional gene expressions. However, the epigenetic mechanisms have long been suspected in helminth parasites lacking the major DNA methyltransferases DNMT1 and DNMT3a/3b. Very little information on the evolutionary status of the epigenetic tools and their role in regulating chromosomal genes is currently available in the parasitic trematodes. We previously suggested the probable role of a DNMT2-like protein (CsDNMT2) as a genuine epigenetic writer in a trematode parasite Clonorchis sinensis. Here, we analyzed the phylogeny of HKMT subfamily members in the liver fluke and other platyhelminth species. The platyhelminth genomes examined conserved genes for the most of SET domain-containing HKMT and Disruptor of Telomeric Silencing 1 subfamilies, while some genes were expanded specifically in certain platyhelminth genomes. Related to the high gene dosages for HKMT activities covering differential but somewhat overlapping substrate specificities, variously methylated histones were recognized throughout the tissues/organs of C. sinensis adults. The temporal expressions of genes involved in eggshell formation were gradually decreased to their lowest levels proportionally to aging, whereas those of some epigenetic tool genes were re-boosted in the later adult stages of the parasite. Furthermore, these expression levels were significantly affected by treatment with DNMT and HKMT inhibitors. Our data strongly suggest that methylated histones are potent epigenetic markers that modulate the spatiotemporal expressions of C. sinensis genes, especially those involved in sexual reproduction.

A Study of Activity Participation Level and Functional Disability for The Elderly Aged Over 65 years (65세 이상 노인의 참여활동수준과 기능장애에 관한 연구)

  • Park, Kyoung-Young;Shin, Su-Jung
    • Journal of Convergence for Information Technology
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    • v.10 no.9
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    • pp.222-228
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    • 2020
  • The purpose of this study was to investigate activity participation level and functional disability based on ICF for the elderly aged over 65 years. Subjects were 100 senior citizens. We performed data collection using Korean Activity Card Sorting(KACS) and World Health Organization Disability Assessment Schedule 2.0(WHODAS 2.0). Data were analyzed using descriptive statistics, Pearson's correlation, multiple regression. As a result of the survey of activity participation levels, retained level of activity participation of instrumental activity was highest at 75.06%. Among the WHODAS 2.0 sub-domain, 'getting along with people', 'participation in society' had the most difficulties and 'self-care', 'life activities' were the lowest. An analysis of the correlation between the activity retention rate and functional disability showed that there was a significant negative correlation. Significant factors influencing functional disability were activity participation level of social activity, instrumental activity and main work(retirement). We confirmed that activity participation level was important factor on functional disability. Further, we need standardization study for generalization.

HIDE, a Testis Specific Deubiquitinating Enzyme, Interacts with HSP90 (고환 특이적으로 발현되는 탈유비퀴틴효소 HIDE와 HSP90의 상호작용)

  • Seong, Minu;Kim, Myung-Sun;Kim, Yong-Soo;Lee, Sook-Hwan;Lee, Hey-Jin;Cha, Kwang Yul;Baek, Kwang-Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.3
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    • pp.231-242
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    • 2005
  • 연구목적: 본 연구는 아직 그 기능이 파악되지 않은 탈유비퀴틴효소 중 하나인 HIDE에 대한 기본적인 생화학적 특징과 고환에서의 발현 양상을 파악하고 있다. 연구재료 및 방법: 인간의 HIDE 유전자를 클로닝하여 효소활성이 있는지 세포 외 실험을 통해 확인하였고, 아미노산 서열을 분석하여 진화상 보존된 부분을 찾아 그 기능을 파악한 다음 HSP90과의 상호작용을 공동면역침전반응으로 확인하였다. HIDE의 조직별 발현양상을 파악하기 위해서 인간과 쥐의 RNA 블롯과 쥐의 단백질 블롯을 이용하여 각각 노던 블롯팅과 웨스턴 블롯팅을 수행하여 고환에서 많이 발현된다는 것을 알았고 이 사실을 바탕으로 쥐의 고환을 절개하여 면역조직화학반응으로써 고환 내의 HIDE 단백질의 발현양상을 파악하였다. 결 과: HIDE는 세포 외에서 유비퀴틴 잔기를 제거하는 탈유비퀴틴 활성이 있으나 세포 내에서 전체적인 유비퀴틴 복합체를 줄여주는 효과는 없었다. HIDE는 HSP90이라는 분자 샤페론과 상호작용한다. HIDE의 전사체는 고환에서 가장 많이 발현되며 다른 조직에서도 소량 발현된다. HIDE의 단백질은 웨스턴 블롯상에서 고환에서만 확인되었다. 고환 내에서의 HIDE의 발현양상은 왕성한 감수분열을 하는 정모세포에서 높았으며 지지세포나 정조세포에는 발현되지 않았다. 결 론: HIDE는 분자 샤페론 HSP90과 상호작용하며 고환 내의 감수분열 중인 세포에서 많이 발현되는 것으로 보아 감수분열이나 정자형성에 관여하는 것으로 보인다.

Analysis about the effect of flipped learning based team activity (플립드 러닝 기반 팀 협동학습 적용 효과분석 연구)

  • Park, Boc-Nam;Shin, Mee-Kyung;Jeon, Hye-Jin
    • Journal of Convergence for Information Technology
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    • v.9 no.6
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    • pp.44-51
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    • 2019
  • This study was performed to explore the difference in communication anxiety and class satisfaction after taking the traditional lecture and flipped learning lecture. Fifty four nursing students participated in this study. The study design was one group pretest-posttest design. 4 weeks traditional lecture and 4 weeks flipped learning lecture was applied. Flipped learning was ineffective in improving communication anxiety (t=1.85, p=.069) of nursing students. But emotional state variables and activity variables in the emotional domain were significantly higher after taking the flipped learning lecture(t=-3.80, p=.000; t=-3.35, p=.001). In addition, all of the variables were higher in the flipped learning based team, in the control of the class activities (t=-3.07, p=.003), personal ability (t=-2.48, p=.016), and class participation(t=-3.25, p=.002). Flipped learning is therefore considered to be effective in training nursing students. This study suggested to investigate the effectiveness of flipped learning and learners' satisfaction.

Study on the Storage of Chestnut (밤 저장(貯藏)에 관(關)한 연구(硏究))

  • Yim, Ho;Kim, Choung-Ok;Shin, Dang-Wha;Suh, Kee- Bong
    • Korean Journal of Food Science and Technology
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    • v.12 no.3
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    • pp.170-175
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    • 1980
  • A mass production of chestnut necessiates the development of economic long-term storage method. The main objective of this study was to confirm the technical aspect of the chestnut storage method which was developed by two year project and to review the method of commercial application. The chestnut used for the experiments were separated in brine $(5.5{\sim}6.0^{\circ}\:B{\acute{a}}ume)$ into matured and unmatured lots and fumigated with $CS_2$ at a 5 $lb/27\;m^3$ level for $25{\sim}30\;hrs.$ The chestnuts were packed in wooden boxes with sawdust (50% moisture) in the ratio of 1 : 1 by volume. The boxes were stored in the cold room $(1{\pm}1^{\circ}C,\;85{\sim}95%\;RH)$ and the cellar ($0{\sim}10^{\circ}C$, controlled only by circulating night cool air). The results obtained were as follows: 1. Fully matured chestnut could be successfully preserved $8{\sim}9\;months$ at a l0% decay level in the cold room and $4{\sim}5\;months$ months in cellar. 2. Immatured chestnuts wire inferior to the matured in storage stability. At the maximum storage period, its storage life was two months shorter. 3. The heat transfer equation of piled chestnuts with sawdust can be suggested as $T_{\infty}-T_0=(T_{\infty}-T_0){\cdot}10^{-t/320}$ and j and $f_h$ values were 1 and 320 min, respectively. 4. The chestnuts in the package of storage unit had longer shelf life than naked chestnut during the retail distribution at ambient temperature.

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Label Embedding for Improving Classification Accuracy UsingAutoEncoderwithSkip-Connections (다중 레이블 분류의 정확도 향상을 위한 스킵 연결 오토인코더 기반 레이블 임베딩 방법론)

  • Kim, Museong;Kim, Namgyu
    • Journal of Intelligence and Information Systems
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    • v.27 no.3
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    • pp.175-197
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    • 2021
  • Recently, with the development of deep learning technology, research on unstructured data analysis is being actively conducted, and it is showing remarkable results in various fields such as classification, summary, and generation. Among various text analysis fields, text classification is the most widely used technology in academia and industry. Text classification includes binary class classification with one label among two classes, multi-class classification with one label among several classes, and multi-label classification with multiple labels among several classes. In particular, multi-label classification requires a different training method from binary class classification and multi-class classification because of the characteristic of having multiple labels. In addition, since the number of labels to be predicted increases as the number of labels and classes increases, there is a limitation in that performance improvement is difficult due to an increase in prediction difficulty. To overcome these limitations, (i) compressing the initially given high-dimensional label space into a low-dimensional latent label space, (ii) after performing training to predict the compressed label, (iii) restoring the predicted label to the high-dimensional original label space, research on label embedding is being actively conducted. Typical label embedding techniques include Principal Label Space Transformation (PLST), Multi-Label Classification via Boolean Matrix Decomposition (MLC-BMaD), and Bayesian Multi-Label Compressed Sensing (BML-CS). However, since these techniques consider only the linear relationship between labels or compress the labels by random transformation, it is difficult to understand the non-linear relationship between labels, so there is a limitation in that it is not possible to create a latent label space sufficiently containing the information of the original label. Recently, there have been increasing attempts to improve performance by applying deep learning technology to label embedding. Label embedding using an autoencoder, a deep learning model that is effective for data compression and restoration, is representative. However, the traditional autoencoder-based label embedding has a limitation in that a large amount of information loss occurs when compressing a high-dimensional label space having a myriad of classes into a low-dimensional latent label space. This can be found in the gradient loss problem that occurs in the backpropagation process of learning. To solve this problem, skip connection was devised, and by adding the input of the layer to the output to prevent gradient loss during backpropagation, efficient learning is possible even when the layer is deep. Skip connection is mainly used for image feature extraction in convolutional neural networks, but studies using skip connection in autoencoder or label embedding process are still lacking. Therefore, in this study, we propose an autoencoder-based label embedding methodology in which skip connections are added to each of the encoder and decoder to form a low-dimensional latent label space that reflects the information of the high-dimensional label space well. In addition, the proposed methodology was applied to actual paper keywords to derive the high-dimensional keyword label space and the low-dimensional latent label space. Using this, we conducted an experiment to predict the compressed keyword vector existing in the latent label space from the paper abstract and to evaluate the multi-label classification by restoring the predicted keyword vector back to the original label space. As a result, the accuracy, precision, recall, and F1 score used as performance indicators showed far superior performance in multi-label classification based on the proposed methodology compared to traditional multi-label classification methods. This can be seen that the low-dimensional latent label space derived through the proposed methodology well reflected the information of the high-dimensional label space, which ultimately led to the improvement of the performance of the multi-label classification itself. In addition, the utility of the proposed methodology was identified by comparing the performance of the proposed methodology according to the domain characteristics and the number of dimensions of the latent label space.