• Proceedings of the KSPS conference
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• 2002.11a
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• pp.165-168
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• 2002

This research was conducted to investigate the priming effect in Korean and English word production by Korean speakers. Picture-naming with distractors was used as experimental task. The type of target language, the type of distractor language and SOA(Stimulus Onset Asynchrony) were used as variables. Cross-linguistic priming effect and within-linguistic priming effect were mesured to investigate bilinguals' conceptual system.

• IMMUNE NETWORK
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• v.11 no.3
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• pp.163-168
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• 2011

Background: Nanoparticles (NPs) prepared from biodegradable polymers, such as poly (D,L-lactic acid-co-glycolic acid) (PLGA), have been studied as vehicles for the delivery of antigens to phagocytes. This paper describes the preparation of antigen-loaded PLGA-NPs for efficient cross-priming. Methods: NPs containing a similar amount of ovalbumin (OVA) but different sizes were produced using a micromixer-based W/O/W solvent evaporation procedure, and the efficiency of the NPs to induce the cross-presentation of OVA peptides were examined in dendritic cells (DCs). Cellular uptake and biodistribution studies were performed using fluorescein isothiocyanate (FITC)-loaded NPs in mice. Results: The NPs in the range of $1.1{\sim}1.4{\mu}m$ in size were the most and almost equally efficient in inducing the cross-presentation of OVA peptides via $H-2K^b$ molecules. Cellular uptake and biodistribution studies showed that opsonization of the NPs with mouse IgG greatly increased the percentage of FITC-positive cells in the spleen and lymph nodes. The major cell type of FITC-positive cells in the spleen was macrophages, whereas that of lymph nodes was DCs. Conclusion: These results show that IgG-opsonized PLGA-NPs with a mean size of $1.1{\mu}m$ would be the choice of biodegradable carriers for the targeted-delivery of protein antigens for cross-priming in vivo.

• Phonetics and Speech Sciences
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• v.9 no.4
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• pp.1-7
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• 2017

It was shown in speech production studies that the preparation unit of spoken word production is language particular, such as onset phonemes for English and Dutch, syllables for Mandarin Chinese, and morae for Japanese. However, there have been inconsistent results on whether the onset phoneme is a planning unit of spoken word production in Korean. In this study, two sets of experiments investigated possible influences of task demands on the phonological preparation in native Korean adults, namely, implicit priming and word naming with the form preparation paradigm. Only the word naming task, but not the implicit priming task, showed a significant onset priming effect, even though there were significant syllable priming effects in both tasks. Following the attentional theory ($O^{\prime}S{\acute{e}}aghdha$ & Frazer, 2014), these results suggest that task demands might play a role in the absence/presence of onset priming effects in Korean. Native Korean speakers could maintain their attention to the shared onset phonemes in word naming, which is not very demanding, while they have difficulties in allocating their attention to such units in a more cognitive-demanding implicit priming, even though both tasks involve accessing phonological codes. These findings demonstrate that there are cross-linguistic differences in the first selectable unit in preparation of spoken word production, but within a single language, the preparation unit might not be immutable.

• Korean Journal of Cognitive Science
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• v.12 no.1_2
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• pp.43-54
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• 2001

This study was conducted to explore the implicit structure of gender-stereotype which is one of the social categories. Social categories were considered to have the more evaluative properties and unclear hierarchical representations compared to the objects or the action categories. In this series of experiments. we want to examine the generalizability of the congruent effect into gender-stereotype using a priming paradigm and introducing the various SOA (stimulus onset asynchrony. SOA 250ms to 1000ms). The results of Experiment 1 and 3 (SOA 250-500ms) showed that the priming effects of female-female condition was larger than the other conditions. However. Experiment 2 (SOA 1000ms) showed that the priming effects among the conditions disappeared. We found the female-congruent effects only in a short SOA. These results suggest the possibility that the gender-stereotype in the automatic and implicit processing level can be represented b by the cross-categorical structure in some cultural area.

• Korean Journal of Medicinal Crop Science
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• v.21 no.1
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• pp.7-19
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• 2013

This study was carried out to select new pelleting binder and material for seeds from Fraxinus rhynchophylla Hance and Alnus sibirica Fisch. ex Turcz. The optimum treatments of the various concentrations and species of priming agents to improve seed germination of both woody medicinal plants were also estimated. Germinability was increased when the seeds of Fraxinus rhynchophylla Hance was soaked in -1.0 MPa of PEG6000 solution at $15^{\circ}C$ for 4 days significantly, the optimum treatment for improving germination of Alnus sibirica Fisch. ex Turcz was observed when the tested seeds was soaked in 100 mM of KCl at $15^{\circ}C$ for 4 days. The influence of physical and chemical properties of pelleting solid materials, the mixture of gypsum, diatomaceous earth, dalma ceramic and vermicuolite (6:1:1:1 ratio) were found as the best pelleting materials for Fraxinus rhynchophylla Hance and Alnus sibirica Fisch. ex Turcz. seeds. To satisfy the requirements of absorption and compatibility for multi-layer seed pelleting, SGPA (Starch-grafted cross-linked polyacrylates) hydrogel was prepared using starch, acrylonitrile, ceric ammonium nitrate, nitric acid, methyl alcohol and potassium hydroxide. The resulting SGPA hydrogel showed high water absorption but not plant compatibility. It suggested that seed pelleting using pelleting materials and SGPA hydrogel (multi-layer coating) after priming agent treatment is to increase germinability and seedling growth and it can reduced irrigation labours and can also save seed.

• Journal of Chest Surgery
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• v.42 no.4
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• pp.418-425
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• 2009

Background: Cardiopulmonary bypass (CPB) involves use of an initial priming volume which can cause side effects such as hemodilution, transfusion, inflammatory reaction and edema. Hence, there have been efforts made tore-duce the initial priming volume. We compared this traditional method to a CPB method that uses a minimized priming volume (MPV). Material and Method: For 97 patients who underwent congenital cardiac surgery between July 2007 to June 2008, we discussed each case and decided which method to use. We reviewed the medical records and cardiopulmonary bypass sheets of the patients. Result: We used a MPV method for 46 patients, and a traditional method for the other 51. There were no significant differences in preoperative and intraoperative characteristics between the two groups, such as body weight, age, cardiopulmonary bypass time, lowest body temperature, etc. However, the priming volume was much smaller in the MPV group than the traditional group (p<0.001). The volume of initially mixed packed RBC was also much smaller in the MPV group (p<0.001). There were no significant differences in postoperative mortality and neurologic complications. Conclusion: We could significantly reduce the initial priming volume and initially mixed pRBC volume with the revised CPB method. We suggest that this method be used more widely for congenital cardiac surgery.

• Phonetics and Speech Sciences
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• v.2 no.3
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• pp.115-124
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• 2010

The current study investigated the role of acoustic correlates of domain-initial strengthening in lexical segmentation of a non-native language. In a series of cross-modal identity-priming experiments, native Korean listeners heard English auditory stimuli and made lexical decision to visual targets (i.e., written words). The auditory stimuli contained critical two word sequences which created temporal lexical ambiguity (e.g., 'mill#company', with the competitor 'milk'). There was either an IP boundary or a word boundary between the two words in the critical sequences. The initial CV of the second word (e.g., [$k_{\Lambda}$] in 'company') was spliced from another token of the sequence in IP- or Wd-initial positions. The prime words were postboundary words (e.g., company) in Experiment 1, and preboundary words (e.g., mill) in Experiment 2. In both experiments, Korean listeners showed priming effects only in IP contexts, indicating that they can make use of IP boundary cues of English in lexical segmentation of English. The acoustic correlates of domain-initial strengthening were also exploited by Korean listeners, but significant effects were found only for the segmentation of postboundary words. The results therefore indicate that L2 listeners can make use of prosodically driven phonetic detail in lexical segmentation of L2, as long as the direction of those cues are similar in their L1 and L2. The exact use of the cues by Korean listeners was, however, different from that found with native English listeners in Cho, McQueen, and Cox (2007). The differential use of the prosodically driven phonetic cues by the native and non-native listeners are thus discussed.

• Asia-Pacific Journal of Business
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• v.14 no.4
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• pp.49-65
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• 2023

Purpose - In the Korean and Chinese social landscape, it is vital to appreciate the significance of the Japanese history problem. The current study investigated whether the perception of the Japanese history problem affects decisions regarding technology adoption in organizations by comparing South Korea and China. Design/methodology/approach - The study involved 305 Korean and 379 Chinese participants who responded to scenarios and surveys regarding the adoption of workplace surveillance cameras supplied by a Japanese company. Findings - Using a moderated mediation model based on protection motivation theory (PMT), we found that past experiences of privacy invasion significantly reduced trust in the adoption of surveillance cameras at work. This relationship was mediated by respondents' perceptions of security vulnerability. The current study, however, did not confirm any significant moderating effect of the Japanese history problem priming on trust in the adoption of workplace surveillance cameras. Research implications - This suggests that the Japanese history problem may have a limited impact on organizational technology adoption decisions, different from the political consumerism behavior driven by public anti-Japanese affectivity. The current study reaffirms the validity and applicability of PMT and provides both theoretical insights and practical recommendations.

• Proceedings of the Korean Society for Cognitive Science Conference
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• 2002.05a
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• pp.157-162
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• 2002

본 연구는 영어 단어 재인 과정에서 나타나는 한국인의 어휘 수준과 의미 수준 양상을 알아보기 위해 실시되었다 이를 위해 본 연구에서는 세 종류의 실험을 시행하였는데, 첫 번째 실험에서는 한국어 처리 기제와 영어 처리 기제의 독립 여부를 알아보기 위하여 한국어로는 여러 의미를 갖지만 영어로는 한 가지 의미만을 가지는 영어단어를 점화 자극으로 하고, 한국어와는 관련된 의미를 갖지만 영어와는 무관련한 한국어 단어를 목표 자극으로 사용하여(예, bridge-팔)언어간 의미 점화 어휘판단 과제를 시행하였다. 두 번째 실험에서는 비교적 개념 구조가 한국어와 영어에서 유사하다고 생각되어지는 외래어를 자극으로 사용하여 언어간(예, elevator-승강기), 언어 내(예, 엘리베이터-승강기) 어휘판단과제를 실시하였다. 연구 결과 첫 번째 실험에서는 유의미한 점화효과가 나타나지 않았고, 두 번째 실험에서는 언어간에는 SOA에 따라서 결과가 달랐고, 언어 내에는 촉진적 점화효과가 나타났다 이러한 결과는 영어의 일반 어휘에 대한 의미 표상 체계는 독립적으로 존재하였고, 외래어와 같이 특수한 어휘에 대해서는 다른 표상 체계를 갖고 있는 것으로 나타났다

• Journal of Life Science
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• v.16 no.6
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• pp.904-910
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• 2006

Dendritic cells (DCs) are the only antigen presenting cells (APCs) capable of initiating immune responses, which is crucial for priming the specific cytotoxic T lymphocyte (CTL) response and tumor immunity. Upon activation by DCs, CD4+ helper T cells can cross-prime CD8+ CTLs via IL-12. However, recently activated DCs were described to prime in vitro strong T helper cell type 1 $(Th_1)$ responses, whereas at later time points, they preferentially prime $Th_2$ cells. Therfore, we examined in this study the optimum kinetic state of DCs activation impacted on in vivo priming of tumor-specific CTLs by using ovalbumin (OVA) tumor antigen model. Bone-marrow-derived DCs showed an appropriate expression of surface MHC and costimulatory molecules after 6 or 7-day differentiation. The 6-day differentiated DCs pulsed with OVA antigen for 8 h (8-h DC) and followed by restimulation with LPS for 24 h maintained high interleukin (IL)-12 production potential, accompanying the decreased level in their secretion by delayed re-exposure time to LPS. Furthermore, immunization with 8-h DC induced higher intracellular $interferon(IFN)-{\gamma}+/CD8+T$ cells and elicited more powerful cytotoxicity of splenocytes to EG7 cells, a clone of EL4 cells transfected with an OVA cDNA, than immunization with 24-h DC. In the animal study for the evaluation of therapeutic or protective antitumor immunity, immunization with 8-h DC induced an effective antitumor immunity against tumor of EG7 cells and completely protected mice from tumor formation and prolonged survival, respectively. The most commonly used and clinically applied DC-based vaccine is based on in vitro antigen loading for 24 h. However, our data indicated that antigen stimulation over 8 h decreased antitumor immunity with functional exhaustion of DCs, and that the 8-h DC would be an optimum activation state impacted on in vivo priming of tumor-specific CTLs and subsequently lead to induction of strong antitumor immunity.