• Korean Journal of Adult Nursing
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• v.19 no.2
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• pp.167-177
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• 2007

Purpose: This cross-sectional survey research was undertaken to identify the factors influencing time from onset to hospital arrival of stroke patients and to provide basic information for the development of intervention programs for stroke patients. Methods: The data were collected using a convenient sampling method from three hospitals in Inchon. The subjects were 78 patients who were diagnosed as stroke by doctor and they voluntarily participated in the study. Results: On the average, subjects arrived at the hospitals by 16.72 hours after the onset of stroke events with the range from 0.17 hours to 72 hours. Thirty-four(43.6%) subjects arrived within 3 hours which can maximize treatment effects. There was significant difference in hospital presentation time according to the level of knowledge(${\chi}^2=18.629$, p=.0003). A negative correlation was found between the hospital presentation time and self-efficacy (r= -.320, p=.004). Stepwise multiple regression analysis revealed that the most powerful predictor was self-efficacy. Self-efficacy, the level of knowledge and physical symptoms were significant factors and accounted for 21.7% of the variance of hospital presentation time in stroke patients. Conclusion: According to the results, self-efficacy is a useful concept for reducing the hospital presentation time from onset of attack in stroke patients. Therefore, nurses should consider educational programs which include not only a knowledge of stroke and recurrence prevention but also the concept of self-efficacy.

• IMMUNE NETWORK
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• v.5 no.3
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• pp.150-156
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• 2005

Background: Dendritic cells (DCs) playa critical role not only in the initiation of immune responses, but also in the induction of immune tolerance. In an effort to regulate immune responses through the modulation of antigen presenting cell (APC) function of DCs, we searched for and characterized APC function modulators from natural products. Methods: DCs were cultured in the presence of propolis components, WP and CP, and then examined for their ability to present exogenous antigen in association with major histocompatibility complexes (MHC). Results: WP and CP inhibited class I MHC-restricted presentation of exogenous antigen (cross-presentation) in a DC cell line, DC2.4 cells, and DCs generated from bone marrow cells with GM-CSF and IL-4. The inhibitory activity of WP and CP appeared to be due not only to inhibition of phagocytic activity of DCs, but also to suppression of expression of MHC molecules on DCs. We also examined the effects of WP and CP on T cells. Interestingly, WP and CP increased IL-2 production from T cells. Conclusion: These results demonstrate that WP and CP inhibit MHC-restricted presentation of exogenous antigen through down-regulation of phagocytic activity and suppression of expression of MHC molecules on DCs.

• IMMUNE NETWORK
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• v.1 no.3
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• pp.196-202
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• 2001

Backgorund: WEHI-231 B cell line is a representative model for $IgM^+$ mature B cells. To understand the signaling differences between mature and immature B cells, we compared the responsiveness of WEHI-231 and Bal 17 B cell lines to BCR cross-linking. Methods: The extents of tyrosine phosphorylation, ligand-induced internalization, and activation-induced cell death upon BCR cross-linking were compared in two cell lines. Results: Despite a higher expression of BCR, cross-linking of BCR on WEHI-231 cell evoked a weaker level of tyrosine phosphorylation and BCR endocytosis than Bal 17 cells. Furthermore, the endocytosed BCR could not enter the lysosomal compartment and stayed as peripheral spots in WEHI-231 cells. Conclusion: WEHI-231 cell showed preferred BCR-mediated signaling pathways leading to a reduced capability of antigen presentation as well as the enhanced apoptosis in comparision with Bal 17 cells. These results might reflect the signaling differences between mature and immature B cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4459-4466
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• 2015

This study was conducted to identify the factors that influence nursing students' adjustment to college life. Self-report questionnaire surveys were conducted toward 333 South Korean nursing students to measure emotional intelligence, perfectionistic self-presentation, and clinical stress. Data were collected from October 20th to December 8th, 2014. The collected data were analyzed by using t-test, one way ANOVA, Pearson correlation coefficient, and multiple linear regression analysis. The results indicated that emotional intelligence, religion, perfectionistic self-presentation significantly influenced on the adjustment to college life and the explanatory power of the model was 27.2%. Based on the study results, we suggest that it is necessary to develop and apply the educational strategy to improve the emotional intelligence for the adjustment to college life.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2439-2443
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• 2016

Purpose: To determine the risk factors, clinical symptoms and patterns of spread in laryngeal cancer. Materials and Methods: A cross sectional study was carried out in the Regional Cancer Centre, Imphal, Manipur, India. One hundred and sixteen patients with laryngeal cancer were retrospectively reviewed for epidemiological data and descriptive statistics were reported for various variables. Results: Median age at presentation was 65 years and 32.8% were undernourished at presentation. The male to female ratio was 5.4:1. Heavy smoking and tobacco chewing was associated in 91.4% and 33.6% of patients respectively. Tracheostomy was required in 21.5% leading to diagnosis of laryngeal cancer. Almost all were squamous cell carcinoma with neuroendocrine and verrucous carcinoma accounting for less than 2%. Supraglottic, glottic and trans-glottic tumors were 56.9%, 36.3% and 6.9% respectively. Nodal metastases were seen in 81.8% of supraglottic cancers and 31.6% of glottic cancers with supraglottic involvement. Level II neck nodes were the commonest site followed by level III. Distant metastases (only liver) were apparent in 1.7% at presentation. Including these liver metastases, unresectable cases were limited to 6% of the patients. Conclusions: Tobacco use is implicated in almost all of the cases and the sex ratio has also decreased due to increased female smokers. The supraglottis remains the commonest site and incidence of nodal metastases is higher than in other countries. There is also a higher requirement for tracheostomy at presentation in this region.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2105-2110
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• 2016

Purpose: A multicenter, observational, cross-sectional study was conducted to assess factors delaying presentation of breast cancer cases. Materials and Methods: Data were collected from a pair of highly specialized referral centers, both located in the center of the Sudanese capital, Khartoum. For a total of 153 eligible respondents, durations of delay, clinicodemographic factors and reasons of referral were collected from our respondents through self-administered questionnaires. Logistic regression analysis and ANOVA were used to test the relation between periods of delay and different factors. Odd ratios (OR's) and their correspondent Confidence intervals (95% CI's). Delay periods were studied with Andersen's model. Results: The average duration of delay in our study was 11.9 (${\pm}11.2$) months. Only a quarter of our patients presented early within the first 3 months after onset of their symptoms. About 47.7% arrived later during the course of the first year, while it took beyond that for the last 27% to come. A prior diagnosis of BC was the only predictor of early presentation (for 3-12 months OR=9.6 (p<0.00), 95% CI 9.55-9.75; for >12 months OR=9.3 (p<0.00), 95% CI 9.33-9.33). Out of the 12 different reasons for delay given by our respondents, none showed a significant difference between patients presenting early or late. Financial incapacity (17.5%), ignorance about BC (14.3), and misinterpreting symptoms (12.7%) were the top three whys of delay. Conclusions: Our findings support existence of a non-uniform pattern of delay among Sudanese BC patients. Changing currently adopted awareness elevating strategies into much more inclusive approaches is strongly recommended.

• Journal of Korean Library and Information Science Society
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• v.42 no.2
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• pp.29-50
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• 2011

An aim of this study is to analyze status of information literacy and propose some ways strengthening its role as a cross-curriculum. Analyses show that information literacy is a basic competency of creative person composing the educational human figure under the national curriculum in Korea. In the school knowledge, its position is a procedural knowledge to create new ideas, also it is a interdisciplinary thinking skill under the instructional method. Therefore, information literacy instruction covering media and ICT literacy should exist as a main cross-curriculum to be a selective subject in the national curriculum. And finally, one of learning skills, its definition should be cleary stated such as information research and access, information analyses and interpretation, information synthesize and presentation.

• Membrane and Water Treatment
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• v.2 no.2
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• pp.105-119
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• 2011

This study presents the tests of an Immersed Membrane BioReactor (IMBR) equipped with a draft tube and focuses on the influence of hydrodynamic conditions on membrane fouling in a pilot-scale using a hollow fiber membrane module of ZW-10 under ambient conditions. In this system, the cross-flow velocities across the membrane surface were induced by a cylindrical draft-tube. The relationship between cross-flow velocity and aeration strength and the influence of the cross-flow on fouling rate (under various hydrodynamic conditions) were investigated using Multi-Dimension Scaling (MDS) analysis. MDS technique is especially suitable for samples with many variables and has relatively few observations, as the data about Membrane Bio-Reactor (MBR) often is. Observations and variables are analyzed simultaneously. According to the results, a specialized form of MDS, CoPlot enables presentation of the results in a two dimensional space and when plotting variables ratio (output/input) rather than original data the efficient units can be visualized clearly. The results indicate that: (i) aeration plays an important role in IMBR performance; (ii) implementing the MDS approach with reference to the variables ratio is consequently useful to characterize performance changes for data classification.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.1247-1250
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• 2008

This presentation highlights work from the authors' laboratories on the various kinds of oxide optical materials, mainly luminescence and pigment materials with different forms (powder, core-shell structures, thin film and patterning) prepared by the Pechini-type sol-gel (PSG) process. The PSG process which uses the common metal salts (nitrates, acetates, chlorides etc) as precursors and citric acid (CA) as chelating ligands of metal ions and polyhydroxy alcohol (such as ethylene glycol or poly ethylene glycol) as cross-linking agent to form a polymeric resin on molecular level, allowing the preparation of many forms of luminescent materials.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.154.1-154.1
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• 2011

IGRINS (Immersion Grating Infrared Spectrometer) is a cross-dispersed high resolution near-infrared spectrograph whose primary disperser is a silicon immersion grating (SIG) and cross-dispersers are two volume phase holographic gratings (VPHG). IGRINS covers the full ranges of H and K astronomical wavelength bands at a single exposure with the spectral resolution of 40,000. The overall layout of the IGRINS Cryostat is a $960{\times}600{\times}380$ cubic millimeter rectangular box and the whole optical train is sitting on an $880{\times}520{\times}50\;mm^3$ rectangular Optical Bench. The total volume of the instrument has been revolutionarily reduced and remained compact for the spectral coverage and sensitivity of a high resolution spectrograph in infrared. We, in this presentation, introduce the design models, the structural and thermal analysis results of the mechanics and cryogenics of IGRINS.