• The Journal of Korean Medicine
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• v.39 no.2
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• pp.80-91
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• 2018

Objectives: The purpose of this study was to investigate stress and health recognition in Korean medical student by gender. Methods: 393 Korean medical student participated in this study. They were surveyed demographic characteristics(gender, age, drinking, morning diet, health recognition and etc), medical stress scale, Maslachh burnout inventory, Korea acceptance and action, and Ego Resilience Scale. For statistical analysis, chi-square test, Student t-test, correlation analysis, and simple regression analysis has been used. Results: In Medical stress scale and ego resilience, it is not significant difference by gender. Female students were significantly higher than male students in Maslach burnout inventory(P=0.015). Male students were significantly higher than female students in Korea Acceptance and Action(P=0.002). Health recognition have negative correlation between medical stress and academic exhaustion, and positive correlation between psychological flexibility and ego resilience. Conclusions: Through these results, we need to further study and develop strategies to reduce stress according to gender in Korean medical college.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2004.09a
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• pp.113-114
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• 2004

In order to classify the groundwater recharge characteristics in an urban area, a time series analysis of groundwater level data was performed. For this study, the daily groundwater level data from 35 monitoring wells were collected for 3 years (Fig. 1). The use of the cross-correlation function (CCF), one of the time series analysis, showed both the close relationship between rainfall and groundwater level change and the lag time (delay time) of groundwater level fluctuation after a rainfall event. Based on the result of CCF, monitored wells were classified into two major groups. Group I wells (n=10) showed a fast response of groundwater level change to rainfall event, with a delay time of maximum correlation between rainfall and groundwater level near 1 to 7 days. On the other hand, the delay time of 17-68 days was observed from Group II wells (n=25) (Fig. 1). The fast response in Group I wells is possibly caused by the change of hydraulic pressure of bedrock aquifer due to the rainfall recharge, rather than the direct response to rainfall recharge.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.661-666
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• 2000

Near-wake flow field of a circular cylinder is studied by means of a cinematic PIV system with high sampling rate and large internal memory block. Experiments are conducted in a closed-cycle water tunnel system and a cross-correlation algorithm in conjunction with FFT (Fast Fourier Transform) analysis and an offset correlation technique is used for vector processing. With the help of very high sampling frequency compared to the shedding frequency, it is possible to obtain phase-averaged information of the three-dimensional wake, even though the shedding is not forced but natural. Phase-locked vortical structures observed simultaneously from the spanwise and cross-stream planes are displayed in the wake-transition regime where fine-scale secondary vortices have a spanwise wavelength or around one diameter. Spatial relations and temporal evolutions of the primary Karman vortex and the secondary vortex are also discussed schematically.

• Industrial Engineering and Management Systems
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• v.1 no.1
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• pp.79-86
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• 2002

This paper proposes a new algorithm for estimating ARMA model parameters. In estimating ARMA model parameters, several methods such as generalized least square method, instrumental variable method have been developed. Among these methods, the utilization of a bootstrap type algorithm is known as one of the effective approach for the estimation, but there are cases that it does not converge. Hence, in this paper, making use of a cross correlation function and utilizing the relation of structural a priori knowledge, a new bootstrap algorithm is developed. By introducing theoretical relations, it became possible to remove terms, which is liable to include much noise. Therefore, this leads to robust parameter estimation. It is shown by numerical examples that using this algorithm, all simulation cases converge while only half cases succeeded with the previous one. As for the calculation time, judging from the fact that we got converged solutions, our proposed method is said to be superior as a whole.

• Journal of Korea Water Resources Association
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• v.49 no.3
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• pp.207-215
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• 2016

In this study, it is analyzed how large scale climate variation has an effect on climate systems over Korea using correlation analysis between climate indices and Intrinsic Mode Functions (IMFs) of precipitation and temperature. For this purpose, the estimated IMFs of precipitation and temperature from the accompanying paper were used. Furthermore, cross correlation coefficients and lag time between climate indices and IMFs were calculated considering periodicities and tendencies. As results, more accurate correlation coefficients were obtained compared with those between climate indices and raw precipitation and temperature data. We found that the Korean climate is closely related with climate variations of $El-Ni{\tilde{n}}o$ in terms of periodicity and its tendency is followed with increasing sea surface temperature due to climate change.

• Journal of Korea Multimedia Society
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• v.8 no.3
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• pp.328-335
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• 2005

This paper proposes a frequency domain independent component analysis (ICA) algorithm to separate the mixed speech signals using a multiple microphone array By estimating the delay timings using a input cross-correlation, even in the delayed mixture case, we propose a good initial value setting method which leads to optimal convergence. To reduce the calculation, separation process is performed at frequency domain. The results of simulations confirms the better performances of the proposed algorithm.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.27 no.8
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• pp.21-29
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• 2013

The functional behaviors of human standing postural control were investigated when they were exposed to long-term horizontal vibration in the sagittal plane. For complexity of human postural control, a useful alternative method that has been based on a black-box approach was taken; that is, where the feedback mechanism was lumped into a single element. A motor-driven support platform was designed as a source of vibration. The AC Servo-controlled motors produced continuous anterior/posterior (AP) motion. The data were analyzed both in the time and frequency domain. The cross-correlation and coherency functions were estimated. Subjects behaved as a non-rigid pendulum with a mass and a spring throughout the whole period of the platform motion, as consistent with the plan chosen for this study.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.202-208
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, Hologram based Quantitative Structure Activity Relationship Study was performed on a series of Xanthine Oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best HQSAR model was obtained using Atoms, Bonds, Connection, Hydrogen, Chirality and Donor Acceptor as fragment distinction parameter using hologram length 71 and 4 components with fragment size of minimum 2 and maximum 5. Significant cross-validated correlation coefficient ($q^2$= 0.563) and non cross-validated correlation coefficients ($r^2$= 0.967) were obtained. The model was then used to evaluate the six external test compounds and its $r^2{_{pred}}$ was found to be 0.798. Contribution map show that presence of propyl ring in indole thiazole makes big contributions for improving the biological activities of the compounds. We hope that our HQSAR model and analysis will be helpful for future design of xanthine oxidase antagonists.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.209-215
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• 2017

CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. CXCR2 antagonist may reduce the neutrophil chemotaxis and alter the inflammatory response because the neutrophilic inflammation in the lung diseases is found to be largely regulated through CXCR2 receptor. Hence, in the present study, Topomer based Comparative Molecular Field Analysis (Topomer CoMFA) was performed on a series of CXCR2 antagonist named pyrimidine-5-carbonitrile-6-alkyl derivatives. The best Topomer COMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.487) and non cross-validated correlation coefficients ($r^2$ = 0.980). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.616. The steric and electrostatic contribution map show that presence of bulkier and electropositive group around cyclopropyl ring may contribute more for improving the biological activities of these compounds. The generated Topomer CoMFA model could be helpful for future design of novel and structurally related CXCR2 antagonists.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.192-196
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, topomer based Comparative Molecular Field Analysis (topomer CoMFA) was performed on a series of Xanthine oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best topomer CoMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.572) and non cross-validated correlation coefficients ($r^2$ = 0.937). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.553. The steric and electrostatic contribution map show that presence of bulky and electropositive group in indole thiazole ring is necessary for improving the biological activities of the compounds. The generated topomer CoMFA model could be helpful for future design of novel and structurally related xanthine oxidase antagonists.