• 한국방사선학회논문지
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• 제12권6호
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• pp.737-743
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• 2018

전산화 단층촬영 장치의 정 도관리 항목 중 하나인 환자 피폭선량 피폭 시험은 의료법 제38조 특수의료장비 설치 및 운영에 따라 1년마다 측정을 시행하고 기록을 보관해야 한다. 선량 측정을 위해 사용되고 있는 CT-Dose 팬텀은 정확한 선량 측정이 가능하지만 가격이 비싸다는 단점이 있다. 따라서 본 연구를 통해 기존의 CT-Dose 팬텀을 3D프린터로 유사하게 제작하여 기존의 팬텀과 비교 분석하고 유용성을 알아보았다. 기존의 CT-Dose팬텀과 동일한 팬텀을 제작하기위해 PLA 필라멘트를 이용하여 FFF 방식의 3D프린터를 이용하였으며, CTDIw 값을 산출하기 위해 팬텀의 주변부와 중앙부에 이온챔버를 삽입하여 각 10번씩 측정하였다. 측정결과 주변부는 CT-Dose팬텀 $30.44{\pm}0.31mGy$, 중앙부는 $29.55{\pm}0.34mGy$ CTDIw값은 $30.14{\pm}0.30mGy$로 측정되었고, 3D프린터를 이용하여 제작된 팬텀은 주변부 $30.59{\pm}0.18mGy$, 중앙부 $29.01{\pm}0.04mGy$, CTDIw값은 $30.06{\pm}0.13mGy$로 측정되었다. SPSS 통계 프로그램의 Mann- Whiteney U-test를 사용하여 분석한 결과 중앙부의 결과 값은 통계적으로 유의한 차이가 있었지만 주변부와 CTDIw의 결과 값은 통계적으로 유의한 차이를 나타내지 않았다. 결론적으로, 3D프린터를 이용하여 제작된 팬텀으로 기존의 CT-Dose 팬텀과 유사한 선량측정 성능을 보였으며, 본 연구를 통해 3D프린터를 이용한 저비용의 팬텀 제작의 가능성을 확인할 수 있었다.

• 한국전통조경학회지
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• 제29권3호
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• pp.116-123
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• 2011

본 연구는 조선왕릉 연지보존 및 복원을 위한 기초연구로 고문헌(춘관통고, 광릉지)에 그 기록이 남아 있으며, 비교적 원형이 잘 보존된 남양주 광릉, 효릉, 김포 장릉, 숭릉의 연지를 대상으로 형태, 재료, 구조 및 공법, 식생적 특성 및 전형에 관하여 살펴보았다. 조선왕릉 연지형태는 평면적으로는 방지원도형 혹은 방지형이며, 크기는 가로 7.5~81m, 세로 6.5~45m, 섬의 직경은 8~16m, 수심은 0.5~1.2m, 단면은 연지의 밑 부분은 좁고 윗부분으로 갈수록 넓은 형태로 조성되었다. 연지바닥은 진흙이 쓰인 것으로 볼 때 흙이 주재료이며, 연지의 구조 및 공법은 토축으로 들여쌓은 지안이 전형으로 보이며, 물의 입수와 배수는 암거수로를 통해 이루어졌다. 연지식생은 현재 많은 수종이 재식되어 있으나, 문헌과 현황을 비교해 보았을 때, 연지 내부는 연꽃, 연지 주변은 소나무 전나무 기타 화훼류 그리고 섬 안은 소나무가 재식되었음을 파악할 수 있었다. 한편, 궁궐 연지를 비교한 결과, 형태와 식생적인 측면에서는 큰 차이가 없었으나, 장대석이라는 재료의 차이에 따라 그 구조 및 공법에도 차이가 있음을 파악할 수 있었다. 이에 본 연구에서는 조선왕릉 연지의 특성을 분석하고 전형을 구명함으로써, 향후 조선왕릉 연지를 재현하는데 기본적 준거를 제공하였다는 긍정적 측면이 있다.

• 지능정보연구
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• 제27권4호
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• pp.49-71
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• 2021

문제해결을 위해 지식을 활용하는 사용자는 내용 면에서 관련된 또 다른 지식, 즉 연관지식에 대한 교차적이고 순차적인 탐색을 진행한다. 지식지도는 관리하는 지식의 현황을 보여주는 도식이자 지식저장소의 분류체계로서, 지식 간 연관성에 기반한 사용자의 지식 탐색을 지원하는 도구이다. 따라서 지식지도는 지식 간 연관성에 의한 네트워크 형식으로 표현되며, 이를 정의 및 추론하는 데에 최적화된 기술을 접목하여 구현되어야 한다. 이를 위해 본 연구는 관리하는 개체와 개체 간 관계를 표현 및 추론하는 데에 최적화된 기능성을 발휘하는 것으로 알려진 그래프DB를 이용하여 지식그래프 기반 지식지도를 개발하는 방법론을 제시한다. 제시된 방법론의 유효성을 확인하기 위하여, 선행 연구의 온톨로지 기반 지식지도 구축 사례 데이터를 그래프DB에 적용하여 지식그래프 기반 지식지도를 구현하고, 구현된 지식 네트워크의 유효성과 Class 자동 구성 능력을 선행 연구의 결과와 비교하는 성능 테스트를 진행한다. 성능 테스트 결과, 본 연구의 지식그래프 기반 지식지도는 선행 연구의 온톨로지 기반 지식지도와 동일한 수준의 성능을 나타냈으며, 지식 및 지식 간 관계 정의 및 추론을 더욱 효율적으로 진행할 수 있음을 확인하였다. 본 연구의 결과는 연관지식에 대한 사용자의 인지과정을 반영한 지식 탐색 기능의 구현에 활용될 수 있으며, 추론에 의한 새로운 연관지식의 발견을 통해 자율적으로 확장되는 지능적 지식베이스의 개발에 응용될 수 있다.

• 한국방사선학회논문지
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• 제17권3호
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• pp.315-325
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• 2023

본 연구는 복부 비만도에 따라 콩팥 크기의 상관관계를 분석하여 3차원 전산화단층영상(3-Dimensional Computed Tomography, 3D CT)의 콩팥 크기 계측으로 복부 비만도를 예측하고자 하였다. 대상자는 전주 예수병원 건강의학센터에서 종합검진을 받은 자로 기저질환이 없는 건강한 성인 178명으로 하였다. 복부 비만도는 CT의 배꼽 주변의 횡단면에서 내장지방 면적, 피하지방 면적, 비만도로 구분하여 측정하였다. 복부 비만도 간에 따라 분류한 콩팥 크기의 평균 비교는 일원배치 분산분석(One-way analysis of variance, ANOVA) 및 Scheffe 사후 검정을 통해 시행하였다. 모든 계측 값의 상관관계는 Pearson 상관분석 하였다. 그 결과 복부 비만도에 따른 콩팥 크기 ANOVA 분석 결과는 다음과 같다. 내장 지방도 간에 따른 콩팥 계측치의 평균은 모든 콩팥 계측치에서 유의한 차이가 있었다(p<0.05). 피하 지방도 간에 따른 콩팥 계측치의 평균은 3D CT 우측 콩팥 너비 계측 시 중증 비만군에서 유의한 차이를 보였다(p<0.05). 비만도 간에 따른 콩팥 계측치의 평균은 3D CT 우측 콩팥 너비와 좌측 콩팥 너비 계측 시 중증 비만군에서 유의한 차이를 보였다(p<0.05). 콩팥 계측치와 CT 복부 비만도 간의 Pearson 상관분석 결과 내장지방 면적은 3D CT 좌측 콩팥 너비와 상대적으로 높은 양의 상관관계(r=0.467)를 보였으며 피하지방 면적은 3D CT 우측 콩팥 너비와 양의 상관관계(r=0.249)를 보였다. 비만도에서는 3D CT 좌측 콩팥 너비와 양의 상관관계(r=0.291)를 보였다.

• 한국구조물진단유지관리공학회 논문집
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• 제27권2호
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• pp.17-24
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• 2023

이 논문은 total flux leakage (TFL) 방법을 이용해 외부텐던을 비파괴검사 하는 솔레노이드 형태의 센서의 측정 신호를 후처리하는 방법을 소개한다. 기존에 개발된 TFL 솔레노이드 센서는 1차 코일과 2차 코일로 이루어져 1차 코일에 정현파 형태의 교류를 입력하면 2차 코일에 그 미분에 비례하는 신호가 측정된다. 이때 진폭은 텐던의 단면에 비례하므로 파단 및 부식 여부를 확인할 수 있다. 따라서 TFL센서의 측정신호에서 진폭정보를 추출 하는 것이 중요한데 기존에는 단순히 극댓값을 모아 진폭정보를 취득했다. 하지만 이 방법을 사용하면 측정빈도가 크게 낮아져 추가적인 신호처리 및 인공지능 적용에 많은 제약이 생긴다. 이 논문은 높은 측정빈도를 가진 진폭정보를 추출하기 위해 진폭복조를 응용해 진폭정보를 획득하는 방법을 제시한다. 진폭복조를 이용해 진폭정보를 취득하면 측정빈도를 원시신호와 동일한 수준으로 유지할 수 있다. 이 방법은 TFL센서의 1차 코일 입력 주파수 선택과 센서를 외부텐던에 적용하는 속도 등에 제약을 없애주어 개발 방향에 많은 자유도를 부여한다. 또한 높은 측정빈도를 유지하므로 추가적인 신호처리나 인공지능 등을 활용 하는데 유리함을 제공한다. 제안된 방법은 실내실험을 통해 검증 되었으며 기존 방법과 비교해 어떤 장점이 있는지 분석했다. 제시된 예제의 경우 진폭복조를 사용한 방법이 기존 방법에 비해 100배 높은 측정빈도를 제공 하는 것을 확인 할 수 있었다. 주어진 상황과 구체적인 장비 설정에 따라 차이가 있겠지만 대부분의 경우 진폭복조를 사용해 진폭정보를 추출하면 기존 방법 대비 만족할만한 결과를 얻을 수 있을 것이다.

• 대한원격탐사학회지
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• 제39권5_3호
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• pp.933-948
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• 2023

대기 중 에어로졸은 인체에 악영향을 끼칠 뿐 아니라 기후 시스템에도 직간접적인 영향을 미치므로 에어로졸의 특성과 시공간적인 분포에 대한 이해는 매우 중요하다. 이를 위해 위성기반 관측을 통해 에어로졸 광학 두께(Aerosol Optical Depth, AOD)를 산출하여 에어로졸을 모니터링하는 다양한 연구가 수행되어 왔다. 하지만 이는 주로 조견표를 활용한 역 산출 알고리즘에 기반하여 이루어지기 때문에 많은 계산량을 요구하며 불확실성이 존재한다. 따라서, 본 연구에서는 Geostationary Ocean Color Imager-II (GOCI-II)의 대기상한반사도와 30일 동안의 대기상한반사도 중 최솟값과 관측 시점 값의 차이 값, 수치 모델 기반 기상학적 변수 등을 활용하여 기계학습 기반 고해상도 AOD 직접 산출 알고리즘을 개발하였다. Light Gradient Boosting Machine (LGBM) 기법이 사용되었으며, 추정된 결과는 지상 관측 자료인 Aerosol Robotic Network (AERONET) AOD를 활용하여 랜덤, 시간 및 공간별 N-fold 교차검증을 통해 검증되었다. 세 가지 교차검증 결과 R²=0.70-0.80, RMSE=0.08-0.09, 기대오차(Expected Error, EE) 안에 있는 비율은 75.2-85.1% 수준으로 안정적인 성능을 보였다. Shapley Additive exPlanations (SHAP) 분석에서는 반사도 관련 변수들이 기여도의 상위권 대부분을 차지하고 있는 것을 통해 반사도 자료가 AOD 추정에 많은 기여를 하는 것을 확인하였다. 서울과 울산 지역에 대한 시간 별 AOD의 공간 분포를 분석한 결과, 개발된 LGBM 모델은 시간의 흐름에 따라 AERONET AOD 값과 유사한 수준으로 AOD를 추정하고 있었다. 이를 통해 높은 시공간 해상도(i.e., 시간별, 250 m)에서의 AOD 산출이 가능함을 확인하였다. 또한, 산출 커버리지 비교에서 LGBM 모델의 평균 산출 빈도가 GOCI-II L2 AOD 산출물 대비 8.8%가량 증가한 것을 통해 기존 물리모델기반 AOD 산출 과정에서 발생하던 밝은 지표면에 대한 과도한 마스킹의 문제점을 개선시킨 것을 확인하였다.

• 심성연구
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• 제28권2호
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• pp.107-138
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• 2013

현대 임상정신의학이 그동안 잊어버렸거나 소홀히 해온 문화와 심성의 관계를 다음과 같은 내용으로 살펴보았다. 1. 문화 :01) 문화정신의학의 공적과 한계 및 그 해결책 ; 2) C.G. 융의 비 서구문화의 경험 ; 3) 융의 분석심리학적 입장에서 본 문화 ; 4) 문화스펙트럼 모델 2. 심성 :01) 원시시대 및 고대의 심(心) 신(身)관 ; 2) 동양적 심성론 ; 3) 자기Self와 동양사상 문화정신의학은 정신건강문제의 문화적 요인을 규명함으로써 정신의학에 큰 기여를 해왔으나 문화적 차이에만 관심을 집중한 나머지 인류보편의 공통된 심성을 도외시하는 경향이 있었고, 인간의 건강한 심성을 등한시하고 문화의 역사적 측면을 간과하였으며 문화 상호간의 역동적 상호관계의 무의식적 심층적 측면을 보지 못했다. C.G. 융의 여행을 통한 이異 문화 체험 양식과 C.G. 융의 분석심리학설은 이 점에서 문화정신의학의 한계를 넘을 수 있는 가능성을 제시했다. 이에 따르면 인류학자들의 문화에 대한 다양한 개념 속에는 집단적 의식collective consciousness뿐 아니라 집단적 무의식에 뿌리박은 내용이 발견된다. 저자는 이를 효孝를 예로 설명했다. 저자는 또한 문화 스펙트럼cultural spectrum이라는 설명모형을 제창하였는데 한국인의 경우 샤머니즘, 불교, 도교, 유고, 기독교 문화가 한 개체의 인격을 여러 가지 스펙트럼으로 구성됨을 제시하였다. 주로 네 가지 유형을 분류하였는데 그것은 1) 주로 불교문화가 우세한 사람, 2) 주로 유교문화가 우세한 사람, 3) 주로 샤머니즘문화가 우세한 사람, 4) 주로 기독교문화가 우세한 사람이다. 비록 의식표면은 하나의 종교문화가 우세하지만 내면에는 다른 종교문화가 섞이게 되며 가장 심층에 샤머니즘 문화를 공유하고 있다고 보았다. 문화와 정신건강의 관계를 이해하고 치유의 접근을 할 때 이러한 스펙트럼 시각이 필요하다. 저자는 인간심성에 대한 고대중국의 개념과 동양종교의 관념, 그리고 C.G. 융의 자기개념에 대한 이해를 소개하고 이에 비길 수 있는 전체정신의 중심에 관한 한국의 선사, 원효의 생각, 대승기승론의 일심(一心), 노자의 도(道), 이퇴계의 천명도(天命圖), 이기설(理氣說)을 융의 분석심리학적 입장에서 해석하였다. 궁극적으로 정신요법의 목적은 분석심리학적 입장에서는 '하나가 되는 것' 이며 '하나'가 됨은 문화에 제약된 인간으로서가 아니라 문화를 포함하나 이를 넘어선 인간 심성 전체가 되도록 하는 것이다.

• 생물환경조절학회지
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• 제32권4호
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• pp.434-441
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• 2023

식물의 잎의 크기나 면적을 아는 것은 생장을 예측하고 실내 농장의 생산성의 향상에 중요한 요소이다. 본 연구에서는 상추 잎 사진을 이용해 엽장과 엽폭을 예측할 수 있는 CNN기반 모델을 연구하였다. 데이터의 한계와 과적합 문제를 극복하기 위해 콜백 함수를 적용하고, 모델의 일반화 능력을 향상시키기 위해 K겹교차 검증을 사용했다. 또한 데이터 증강을 통한 학습데이터의 다양성을 높이기 위해 image generator를 사용하였다. 모델 성능을 비교하기 위해 VGG16, Resnet152, NASNetMobile 등 사전학습된 모델을 이용하였다. 그 결과 너비 예측에서 R² 값0.9436, RMSE 0.5659를 기록한 NASNetMobile이 가장 높은 성능을 보였으며 길이 예측에서는 R² 값이 0.9537, RMSE가 0.8713로 나타났다. 최종 모델에는 NASNetMobile 아키텍처, RMSprop 옵티마이저, MSE 손실 함수, ELU 활성화함수가 사용되었다. 모델의 학습 시간은 Epoch당평균73분이 소요되었으며, 상추 잎 사진 한 장을 처리하는 데 평균0.29초가 걸렸다. 본 연구는 실내 농장에서 식물의 엽장과 엽폭을 예측하는 CNN 기반 모델을 개발하였고 이를 통해 단순한 이미지 촬영만으로도 식물의 생장 상태를 신속하고 정확하게 평가할 수 있을 것으로 기대된다. 또한 그 결과는 실시간 양액 조절 등의 적절한 농작업 조치를 하는데 활용됨으로써 농장의 생산성 향상과 자원 효율성을 향상시키는데 기여할 것이다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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• pp.17-17
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• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.