• Title/Summary/Keyword: Cross-Impact

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Investigating the Au-Cu thick layers Electrodeposition Rate with Pulsed Current by Optimization of the Operation Condition

  • Babaei, Hamid;Khosravi, Morteza;Sovizi, Mohamad Reza;Khorramie, Saeid Abedini
    • Journal of Electrochemical Science and Technology
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    • v.11 no.2
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    • pp.172-179
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    • 2020
  • The impact of effective parameters on the electrodeposition rate optimization of Au-Cu alloy at high thicknesses on the silver substrate was investigated in the present study. After ensuring the formation of gold alloy deposits with the desired and standard percentage of gold with the cartage of 18K and other standard karats that should be observed in the manufacturing of the gold and jewelry artifacts, comparing the rate of gold-copper deposition by direct and pulsed current was done. The rate of deposition with pulse current was significantly higher than direct current. In this process, the duty cycle parameter was effectively optimized by the "one factor at a time" method to achieve maximum deposition rate. Particular parameters in this work were direct and pulse current densities, bath temperature, concentration of gold and cyanide ions in electrolyte, pH, agitation and wetting agent additive. Scanning electron microscopy (SEM) and surface chemical analysis system (EDS) were used to study the effect of deposition on the cross-sections of the formed layers. The results revealed that the Au-Cu alloy layer formed with concentrations of 6gr·L-1 Au, 55gr·L-1 Cu, 24 gr·L-1 KCN and 1 ml·L-1 Lauryl dimethyl amine oxide (LDAO) in the 0.6 mA·cm-2 average current density and 30% duty cycle, had 0.841 ㎛·min-1 Which was the highest deposition rate. The use of electrodeposition of pure and alloy gold thick layers as a production method can reduce the use of gold metal in the production of hallow gold artifacts, create sophisticated and unique models, and diversify production by maintaining standard karats, hardness, thickness and mechanical strength. This will not only make the process economical, it will also provide significant added value to the gold artifacts. By pulsating of currents and increasing the duty cycle means reducing the pulse off-time, and if the pulse off-time becomes too short, the electric double layer would not have sufficient growth time, and its thickness decreases. These results show the effect of pulsed current on increasing the electrodeposition rate of Au-Cu alloy confirming the previous studies on the effect of pulsed current on increasing the deposition rate of Au-Cu alloy.

A Study on the Development Methodology of the U-City Service Scenarios which Apply the Scenario Management Techniques (시나리오 경영기법을 적용한 U-City 서비스 시나리오 개발 방안 연구: u-수질 모니터링 서비스를 중심으로)

  • Seo, Hyun-Sik;Lee, Jong-Myun;Oh, Jay-In
    • Information Systems Review
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    • v.11 no.2
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    • pp.23-44
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    • 2009
  • U-Services are inevitably essential for the realization of u-Cities. Most local governments in Korea have expressed much interest in introducing u-Cites and related u-Services. Since researchers anticipate that developing u-Cities will produce economic effects, the Korea government has support local governments to develop u-Cities and necessary u-Services. However, the technology issues have been dominiated in the field of U-City services and most of the U-City services do not reflects all the complicated and pluralistic sides of environment, which are caused by future uncertainties in developing u-Cites. For the purpose of addressing the above uncertainties, this paper attempts to develop the possible scenarios for U-City services through a scenario planning approach. A focus group interview and survey with professionals in the field of planning u-Cities was performed to identify these uncertainties. Then, in order to investigate the validity of the scenario planning methodology, the u-Service "u-Water purity monitoring" is adopted. After considering the relevant issues, we developed two possible scenarios: a mutual linkage service among u-Service related organization and a cooperating and coordinating service among local governments. On the basis of these scenarios, the strategies for potential U-City services are formulated. Various participants in developing U -City services are encouraged to use the scenarios as the foundation of predicting future features of u-Cities and developing the framework of the U-City service scenarios effectively.

A numerical study on the behavior of existing and enlarged tunnels when widened by applying the pre-cutting method (Pre-cutting 공법을 적용한 터널 확폭 시 기존 및 확폭터널의 거동에 관한 수치해석적 연구)

  • Kim, Han-Eol;Nam, Kyoung-Min;Ha, Sang-Gui;Yoo, Han-Kyu
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.4
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    • pp.451-468
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    • 2020
  • Aging tunnels with small cross-sections can cause chronic traffic jams. This problem can be solved by widening the tunnel. In general, when the tunnel is expanded, the outer portion of the existing tunnel is excavated through a mechanical or blasting method. Such excavation affects not only the surrounding ground but also the existing tunnel. The application of the pre-cutting method can be a solution to these problems effectively. Therefore, if the widening of tunnel is performed by applying pre-cutting method, analysis of the impact of this method must be performed. In this study, in order to analyze the effect of applying pre-cutting in tunnel widening, numerical analysis is performed at six ground grades, from grade I to weathered rock. The analysis is performed with the expanding lane and the excavation length of pre-cutting as variables. In addition, the analysis is focused on the displacement of crown of the existing tunnel and the enlarged tunnel. As a result, the crown displacement of the enlarged tunnel is confirmed to converge at the same value regardless of the excavation length of the pre-cutting when the tunnel widening is completed. In the case of existing tunnels, uplift of crown occurs within 5 m of the front of the tunnel surface, and the shorter the excavation length of pre-cutting is found to be effective in preventing the occurrence of uplift.

Incidence and Clinical Characteristic of Venous Thromboembolism in Gynecologic Oncology Patients attending King Chulalongkorn Memorial Hospital over a 10 Year Period

  • Oranratanaphan, S;Termrungruanglert, W;Khemapech, N
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6705-6709
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    • 2015
  • Background: Venous thromboembolisms (VTEs) constitute a group of diseases including deep vein thrombosis (DVT) and pulmonary embolism (PE). They regarded as the second leading cause of death in cancer patients and several studies have confirmed that VTEs have a negative impact on survival and recurrent rate in both ovarian and endometrial cancer cases. The incidence of VTEs differs worldwide and depends on several risk factors including race, underlying disease, lifestyle, body weight, BMI and genetic risk factors. There is heterogeneity of DVT rates between Asian and Western countries. This study was conducted in order to evaluate the character and incidence of VTEs in gynecologic oncology patients in King Chulalongkorn Memorial Hospital over a 10 year period. Materials and Methods: A retrospective chart review was performed with VTEs defined as objective diagnosis of acute DVT or PE with typical symptoms and signs. Diagnoses were approved byan internist and/or confirmed with imaging studies. Data from both outpatient and inpatient sessions of the affected cases from January 2004 to December 2013 were extracted. General characteristics of the patients were collected with details of the diseases, types of cancer, stage, date of diagnosis of cancer, operative data, treatment outcome, progression free survival and overall survival. Results: Thirty cases of VTEs were identified in a total 2,316 gynecologic oncology cases. The incidence of symptomatic VTEs in total gynecologic oncology patients in our institution is 1.295%. The incidence of VTEs in ovarian cancer patients in our institution was 5.9%. Duration for VTE detection ranged from 13 months before diagnosis of cancer to 33 months after diagnosis of cancer. Most of the VTE cases were detected in ovarian cancer patients (60%). The most common cell type was adenocarcinoma (moderately to poorly differentiated) which accounted for 26.7% of the cases. The second most common cell type was clear cell carcinoma with 23.3% of the cases. Thirty percent of VTE cases developed before cancer was diagnosed, 20% were diagnosed at the same time as cancer detection and fifty percent developed after cancer was diagnosed. Median disease free survival of the gynecologic oncology patients with VTE was 7.5 months. Median overall survival (OS) was 12 months. Median progession free survivals of DVT and PE groups were 11.5 and 5.5 months, respectively. OS of DVT and PE was 12.0 and 11.5 months respectively. Conclusions: The incidence of VTE in Asian countries is believed to be lower than in European or Western countries. From our retrospective review, the incidence of VTEs in all types of gynecologic oncology was 1.295%, much lower than reported in the West. The reason for the lower incidence may genetic differences. Another factor is that VTE in this review was symptomatic, which is less than asymptomatic VTE. More than half of VTEs in this study developed in ovarian cancer patients. The results are compatible with earlier reports that among gynecologic malignancies, the incidence of VTE is highest in ovarian cancer.

Impact of HER2 and PTEN Simultaneous Deregulation in Non-small Cell Lung Carcinoma: Correlation with Biological Behavior

  • Panagiotou, Ioannis;Georgiannos, Stavros N.;Tsiambas, Evangelos;Karameris, Andreas;Konstantinou, Marios;Lazaris, Andreas C.;Kavantzas, Nikolaos;Vilaras, George;Patsouris, Efstratios
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6311-6318
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    • 2012
  • Background: HER2/neu overexpression due to gene amplification is an important factor in breast cancer, modifying the sensitivity to anti-HER2 monoclonal antibody therapy. The clinical significance of HER2 expression in non small cell lung carcinoma (NSCLC) is currently under evaluation. The tumor suppressor gene PTEN negatively regulates the HER2/PI3K/Akt signalling pathway. The purpose of this study was to evaluate the role of simultaneous alteration in HER2 and PTEN protein expression in relation to biological behaviour of NSCLCs. Materials and Methods: Protein expression was determined by immunohistochemistry in sixty-one (n=61) NSCLC cases along with CISH for HER2 gene analysis and detection of chromosome 17 aneuploidy. Patients were followed-up for a period of 34 to 41 months after surgery. Results: HER2 overexpression (2+/3+score) was detected in 17 (27.9%) patients while loss of PTEN expression was observed in 24 (39.3%) cases, low expression in 29 (47.6%) and overexpression in 8 (13.1%). Simultaneous HER2 overexpression and PTEN low/loss of expression were correlated with metastasis (71.4% vs 36.2% p=0.03). Analysis in the subgroup of 22 patients of pTNM stage III with lymph node status N1 or N2 revealed that there was a relationship between the number of positive regional lymph node groups and simultaneous deregulation of the two genes (p=0.04). Multivariate analysis determined that HER2 overexpression was associated with an increasing risk of developing metastases (OR: 4.3; 95%CI: 1.2-15.9; p: 0.03) while PTEN overexpression was associated with lower risk (OR: 0.1; 95%CI: 0.1, 1.0; p: 0.05). Conclusions: Simultaneous HER2/PTEN deregulation is a significant genetic event that leads to a more aggressive phenotype of NSCLC.

Predicting the Potential Distribution of Korean Pine (Pinus koraiensis) Using an Ensemble of Climate Scenarios (앙상블 기후 시나리오 자료를 활용한 우리나라 잣나무림 분포 적지 전망)

  • Kim, Jaeuk;Jung, Huicheul;Jeon, Seong Woo;Lee, Dong-Kun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.18 no.2
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    • pp.79-88
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    • 2015
  • Preparations need to be made for Korean pine(Pinus koraiensis) in anticipation of climate change because Korean pine is an endemic species of South Korea and the source of timber and pine nut. Therefore, climate change adaptation policy has been established to conduct an impact assessment on the distribution of Korean pine. Our objective was to predict the distribution of Korean pine while taking into account uncertainty and afforestation conditions. We used the 5th forest types map, a forest site map and BIOCLIM variables. The climate scenarios are RCP 4.5 and RCP 8.5 for uncertainty and the climate models are 5 regional climate models (HadGEM3RA, RegCM4, SNURCM, GRIMs, WRF). The base period for this study is 1971 to 2000. The target periods are the mid-21st century (2021-2050) and the end of the 21st century (2071-2100). This study used the MaxEnt model, and 50% of the presences were randomly set as training data. The remaining 50% were used as test data, and 10 cross-validated replicates were run. The selected variables were the annual mean temperature (Bio1), the precipitation of the wettest month (Bio13) and the precipitation of the driest month (Bio14). The test data's ROC curve of Korean pine was 0.689. The distribution of Korean pine in the mid-21st century decreased from 11.9% to 37.8% on RCP 4.5 and RCP 8.5. The area of Korean pine at an artificial plantation occupied from 32.1% to 45.4% on both RCPs. The areas at the end of the 21st century declined by 53.9% on RCP 4.5 and by 86.0% on RCP 8.5. The area of Korean pine at an artificial plantation occupied 23.8% on RCP 4.5 and 7.2% on RCP 8.5. Private forests showed more of a decrease than national forests for all subsequent periods. Our results may contribute to the establishment of climate change adaptation policies for considering various adaptation options.

Resonance Frequency Analysis of A Baseball Bat by Impact Angle (가진 각도에 따른 야구배트의 공진주파수 분석)

  • Park, Sun-Hyang;Chung, Woo-Yang;Jung, Hwan-Hee;Lee, Sang-Joon
    • Journal of the Korean Wood Science and Technology
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    • v.43 no.6
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    • pp.777-783
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    • 2015
  • Wood is an anisotropic material that shows the changes in hardness, quality and dimensions depending on the types of cells on three cross sections, size, array and so on. It can also be used in different ways according to its use, which requires a meticulous research, in order to maximize the utilization by understanding the nature and use; and by clarifying the theory and technologies. The research on relationship among wood's physical properties, density, and elasticity of modulus have been studied in Korea and abroad, but those studies were based on correlation gained through standardized specimen. Rather, the study on complete product is rare. Moreover, the previous reports are mostly concentrating on vibration mode and batting, though the wood's physical properties as a material have not been in the main focus. Therefore, this study will carried out for analyzing MOE through figuring material property out and comparing frequency adapting to the Canadian HardMaple bat. For comparison of material properties, we studied the annual ring and density of the bat; calculated the MOE with resonance frequency and formula (ASTM C1259); and verified the repulsive force of this material. As a result, the relevance of the resonance frequency and annual ring is weak, and in comparison in the grain direction in wood, the MOE value is higher when the grain direction in wood is excited horizontally than when is excited vertically, because the material is repulsive when grain direction is horizontal.

Impact of Sarcopenia on Early Postoperative Complications in Early-Stage Non-Small-Cell Lung Cancer

  • Lee, Jiyun;Moon, Seok Whan;Choi, Jung Suk;Hyun, Kwanyong;Moon, Young Kyu;Moon, Mi Hyoung
    • Journal of Chest Surgery
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    • v.53 no.3
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    • pp.93-103
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    • 2020
  • Background: Risk assessment for pulmonary resection in patients with early-stage non-small-cell lung cancer (NSCLC) is important for minimizing postoperative morbidity. Depletion of skeletal muscle mass is closely associated with impaired nutritional status and limited physical ability. We evaluated the relationship between skeletal muscle depletion and early postoperative complications in patients with early-stage NSCLC. Methods: Patients who underwent curative lung resection between 2016 and 2018 and who were diagnosed with pathological stage I/II NSCLC were included, and their records were retrospectively analyzed. The psoas volume index (PVI, ㎤/㎥) was calculated based on computed tomography images from routine preoperative positron emission tomography-computed tomography. Early postoperative complications, defined as those occurring within 90 days of surgery, were compared between the lowest sex-specific quartile for PVI and the remaining quartiles. Results: A strong correlation was found between the volume and the cross-sectional area of the psoas muscle (R2=0.816). The overall rate of complications was 57.6% among patients with a low PVI and 32.8% among those with a normal-to-high PVI. The most common complication was prolonged air leak (low PVI, 16.9%; normal-to-high PVI, 9.6%), followed by pneumonia (low PVI, 13.6%; normal-to-high PVI, 7.9%) and recurrent pleural effusion (low PVI, 11.9%; normal-to-high PVI, 6.8%). The predictors of overall complications were low PVI (odds ratio [OR], 2.18; 95% confidence interval [CI], 1.07-4.09; p=0.03), low hemoglobin level (OR, 0.686; 95% CI, 0.54-0.87; p=0.002), and smoking history (OR, 3.93; 95% CI, 2.03-7.58; p<0.001). Conclusion: Low PVI was associated with a higher rate of early postoperative complications in patients with early-stage NSCLC.

Dental Practitioners Self Reported Performance of Tobacco Cessation Counseling Interventions: A Cross Sectional Study

  • Parakh, Abhinav;Megalamanegowdru, Jayachandra;Agrawal, Rohit;Hathiwala, Siddhi;Chandrakar, Mayank;Tiwari, Ram;Veeranna, Thippeswamy
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.6141-6145
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    • 2013
  • Background: The objective of the study was to determine the knowledge, attitude and behaviors of the practicing dentists regarding tobacco cessation counseling (TCC) in Chhattisgarh state and also the barriers that prevent them from doing so. Materials and Methods: The study was conducted among dental practitioners of Raipur district, Chhattisgarh state (India). The sampling frame was registration with the State Dental Council and practicing in Raipur district. A questionnaire was personally administered and the practitioners were given explanations regarding how to complete it. Only descriptive statistics were calculated (SPSS version 16 for Windows). Results: Based on the responding dentists' self reports, 76% were not confident in TCC, 48% did not assume TCC to be their responsibility, 17% considered that it might have a negative impact on their clinical practice, whereas 24% considered it might take away precious time from their practice, 25% considered TCC by dentists to be effective to a considerable extent and 80% considered TCC activities are not effective due to lack of formal training, 69% considered dental clinics as an appropriate place for TCC but 82% thought there must be separate TCC centre and 100% of the dentists wanted TCC training to be a part of practice and that it should be included in dental curriculum. Some 95% of them were of the view that tobacco products should be banned in India and 86% responded that health professionals must refrain from tobacco habits so to act as role models for society. Conclusions: Dental professionals must expand their armamentarium to include TCC strategies in their clinical practice. The dental institutions should include TCC in the curriculum and the dental professionals at the primary and the community health care level should also be trained in TCC to treat tobacco dependence.

Relationship between Urbanization and Cancer Incidence in Iran Using Quantile Regression

  • Momenyan, Somayeh;Sadeghifar, Majid;Sarvi, Fatemeh;Khodadost, Mahmoud;Mosavi-Jarrahi, Alireza;Ghaffari, Mohammad Ebrahim;Sekhavati, Eghbal
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.113-117
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    • 2016
  • Quantile regression is an efficient method for predicting and estimating the relationship between explanatory variables and percentile points of the response distribution, particularly for extreme percentiles of the distribution. To study the relationship between urbanization and cancer morbidity, we here applied quantile regression. This cross-sectional study was conducted for 9 cancers in 345 cities in 2007 in Iran. Data were obtained from the Ministry of Health and Medical Education and the relationship between urbanization and cancer morbidity was investigated using quantile regression and least square regression. Fitting models were compared using AIC criteria. R (3.0.1) software and the Quantreg package were used for statistical analysis. With the quantile regression model all percentiles for breast, colorectal, prostate, lung and pancreas cancers demonstrated increasing incidence rate with urbanization. The maximum increase for breast cancer was in the 90th percentile (${\beta}$=0.13, p-value<0.001), for colorectal cancer was in the 75th percentile (${\beta}$=0.048, p-value<0.001), for prostate cancer the 95th percentile (${\beta}$=0.55, p-value<0.001), for lung cancer was in 95th percentile (${\beta}$=0.52, p-value=0.006), for pancreas cancer was in 10th percentile (${\beta}$=0.011, p-value<0.001). For gastric, esophageal and skin cancers, with increasing urbanization, the incidence rate was decreased. The maximum decrease for gastric cancer was in the 90th percentile(${\beta}$=0.003, p-value<0.001), for esophageal cancer the 95th (${\beta}$=0.04, p-value=0.4) and for skin cancer also the 95th (${\beta}$=0.145, p-value=0.071). The AIC showed that for upper percentiles, the fitting of quantile regression was better than least square regression. According to the results of this study, the significant impact of urbanization on cancer morbidity requirs more effort and planning by policymakers and administrators in order to reduce risk factors such as pollution in urban areas and ensure proper nutrition recommendations are made.