• Annals of Occupational and Environmental Medicine
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• 제35권
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• pp.38.1-38.10
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• 2023

Background: Hearing loss (HL) is linked to an elevated risk of cardiovascular diseases (CVDs). The pathogeneses of HL and CVD commonly involve inflammatory responses. Previous studies investigated elevated levels of inflammatory biomarkers in subjects with HL, however, their findings did not demonstrate statistical significance. In our cross-sectional and longitudinal study, we investigated the correlation between HL and increased high-sensitivity C-reactive protein (hsCRP) levels to determine how HL is associated with CVDs. Methods: We conducted a cross-sectional study with workers aged over 18 years who underwent health check-ups at our institution between 2012 and 2018 (n = 566,507), followed by conducting a longitudinal study of workers aged > 18 who underwent health checkups at least twice at our institution between 2012 and 2018 (n = 173,794). The definition of HL was as an average threshold of ≥ 20 dB in pure-tone air conduction at 0.5, 1.0, and 2.0 kHz in both ears. The incidence of increased hsCRP levels throughout the follow-up period was defined as a level exceeding 3 mg/L. Logistic regression and generalized estimating equations were performed to estimate the risk of increased hsCRP levels according to the occurrence of HL in groups stratified by age. Results: In the cross-sectional study, the multivariate-adjusted odds ratio (OR) was 1.17 (95% confidence interval [CI]: 1.02-1.34); the OR was 0.99 (95% CI: 0.80-1.22) in those under 40 and 1.28 (1.08-1.53) in those over 40. In the longitudinal study, the multivariable-adjusted OR was 1.05 (95% CI: 0.92-1.19); the OR was 1.10 (95% CI: 0.90-1.35) in those under 40 and 1.20 (1.01-1.43) in those over 40. Conclusions: This cross-sectional and longitudinal study identified an association between HL and increased hsCRP levels in workers aged over 40 years.

• Korea-Australia Rheology Journal
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• 제15권2호
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• pp.91-96
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• 2003

The sensitivity of the product to the ongoing sinusoidal disturbances of the process has been investigated in the film casting of viscoelastic polymer fluids using frequency response analysis. As demonstrated for fiber spinning process (Jung et al., 2002; Devereux and Denn, 1994), this frequency response analysis is useful for examining the process sensitivity and the stability of extensional deformation processes including film casting. The results of the present study reveal that the amplification ratios or gains of the process/product variables such as the cross-sectional area at the take-up to disturbances exhibit resonant peaks along the frequency regime as expected for the systems having hyperbolic characteristics with spilt boundary conditions (Friedly, 1972). The effects on the sensitivity results of two important parameters of film casting, i.e., the fluid viscoelasticity and the aspect ratio of the casting equipment have been scrutinized. It turns out that depending on the extension thinning or thickening nature of the fluid, increasing viscoelasticity results in enlargement or reduction of the sensitivity, respectively. As regards the aspect ratio, it has been found that an optimum value exists making the system least sensitive. The present study also confirms that the frequency response method produces results that corroborate well those by other methods like linear stability Analysis and transient solutions response. (Iyengar and Co, 1996; Silagy et al., 1996; Lee and Hyun, 2001).

• 한국기계가공학회지
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• 제19권11호
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• pp.29-34
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• 2020

In this study, a sensitivity formulation was applied to analyze the dynamic response due to the effect of the excitation force for the undamped vibration of the cantilever beam. The theoretically fundamental formulations were derived considering an eigenvalue problem and its modal analysis to govern the second order algebraic differential equation in terms of the change in the modal coordinate with respect to the design parameters. A representative physical quantity pertaining to the dynamic response, that is, the rate of change in the dynamic displacement, was observed by changing the design variables, such as the cross-sectional area of the beam. The numerical results were obtained at various locations, considering the application of the external forces and observation of the dynamic displacement. When the detection position was closer to the free end of the cantilever beam, the sensitivity of the dynamic displacement was higher, as predicted through the oscillating motion of the beam. The presented findings can provide guidance to compute the dynamic sensitivity for a flexibly connected structure under dynamic excitations.

• The Korean Journal of Pain
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• 제33권1호
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• pp.60-65
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• 2020

Background: Anatomic changes in the acromion have been considered a main cause of shoulder impingement syndrome (SIS). To evaluate the relationship between SIS and the acromion process, we devised a new morphological parameter called the acromion process cross-sectional area (APA). We hypothesized that the APA could be an important morphologic diagnostic parameter in SIS. Methods: We collected APA data from 95 patients with SIS and 126 control subjects who underwent shoulder magnetic resonance imaging (MRI). Then we measured the maximal cross-sectional area of the bone margin of the acromion process on MRI scans. Results: The mean of APAs were 136.50 ± 21.75 ㎟ in the male control group and 202.91 ± 31.78 ㎟ in the male SIS group; SIS patients had significantly greater APAs (P < 0.001). The average of APAs were 105.38 ± 19.07 ㎟ in the female control group and 147.62 ± 22.90 ㎟ in the female SIS group, and the SIS patients had significantly greater APAs (P < 0.001). The optimal APA cut-off in the male group was 165.14 ㎟ with 90.2% sensitivity, 91.4% specificity, and an area under the curve (AUC) of 0.968. In the female group, the optimal cut-off was 122.50 ㎟ with 85.2% sensitivity, 84.9% specificity, and an AUC of 0.928. Conclusions: The newly devised APA is a sensitive parameter for assessing SIS; greater APA is associated with a higher possibility of SIS. We think that this result will be helpful for the diagnosis of SIS.

• 한국유체기계학회 논문집
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• 제3권4호
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• pp.15-21
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• 2000

An anemometer employing the bulk PTC thermistor as the sensing element is investigated in this study. The numerical and experimental works are carried out to improve the sensitivity problem of the element by focusing fluid dynamics point of view. The typical shape of the sensing element has been used as a rectangular type, but this shape has a sensitivity problem because of flow separations on the sharp edge when the flow direction is different from that of the sensing element. In order to reduce the reading error, the installer has to be very careful about the flow direction. The reading error fluctuation by time as well as the sensitivity problem can be improved considerably through this study. It can be concluded that the small change of the sensor shape can improve the performance of the flow sensor.

• 한국항해학회지
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• 제25권4호
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• pp.461-469
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• 2001

The purpose of this paper is the optimum modification of dynamic characteristics of stiffened plate structure including the number of stiffener. This paper shows the optimum structural modification method by dynamic sensitivity analysis and quasi-least squares method and considers it's validity. In the method of the optimization, finite element method, sensitivity analysis and optimum structural modification method are used. The change of natural frequency and total weight are made to be an objective function. Thickness of plate, the number of stiffener and cross section moment of stiffener become a design variable. The dynamic characteristics of stiffened plate structure is analyzed using finite element method. Next, rate of change of dynamic characteristics by the change of design variable is calculated using the sensitivity analysis. Then, amount of change of design variable is calculated using optimum structural modification method. It is shown that the results are effective in the optimum modification for dynamic characteristics of the stiffened plate structure including the number of stiffener.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2000년도 제 25회 정기총회 및 추계학술발표회
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• pp.51-58
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• 2000

The purpose of this study is the optimum modification of dynamic characteristics of stiffened plate structure. In the method of the optimization ,finite element method (FEM), sensitivity analysis and optimum structural modification method are used. To begin with, using FEM, the dynamic characteristics of stiffened plate structure is analyzed. Next, rate of change of dynamic characteristic by the change of design variable is calculated using the sensitivity analysis. Then, amount of change of design variable is calculated using this sensitivity value and optimum structural modification method. The change of natural frequency is made to be an objective function. Thickness of plate and cross section moment become a design variable. It is shown that the results are effective in the optimum modification for dynamic characteristics of the stiffened plate structure.

• 한국생산제조학회지
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• 제7권5호
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• pp.106-112
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• 1998

Experience and experiments show that in many cases the buckling limit is reached at a much smaller load level than is predicted by linear buckling analysis. In this paper, it is considered linear and nonlinear of plane vehicle structure and estimates design sensitivity of the cross sectional area that is composed plane vehicle structure and performs optimal design. It compares linear vehicle structure with nonlinear vehicle structure for optima design result that is selected constraint condition of buckling load.

• Structural Monitoring and Maintenance
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• 제9권2호
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• pp.157-177
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• 2022

In this paper, an innovative finite element updating method is presented based on the variation wavelet transform coefficients of Auto/cross-correlations function (WTCF). The Quasi-linear sensitivity of the wavelet coefficients of the WTCF concerning the structural parameters is evaluated based on incomplete measured structural responses. The proposed algorithm is used to estimate the structural parameters of truss and plate models. By the solution of the sensitivity equation through the least-squares method, the finite element model of the structure is updated for estimation of the location and severity of structural damages simultaneously. Several damage scenarios have been considered for the studied structure. The parameter estimation results prove the high accuracy of the method considering measurement and mass modeling errors.

• Applied Microscopy
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• 제51권
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• pp.10.1-10.9
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• 2021

We investigate the sensitivity of symmetry quantification algorithms based on the profile R-factor (R_p) and the normalized cross-correlation (NCC) coefficient (γ). A DM (Digital Micrograph^©) script embedded in the Gatan digital microscopy software is used to develop the symmetry quantification program. Using the Bloch method, a variety of CBED patterns are simulated and used to investigate the sensitivity of symmetry quantification algorithms. The quantification results show that two symmetry quantification coefficients are significantly sensitive to structural changes even for small strain values of < 1%.