• Journal of Microbiology and Biotechnology
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• 제10권5호
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• pp.595-598
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• 2000

Aeromonas hydrophila is a pathogen to fish as well as human. It is a food-borne disease, and causes severe mortality in fish, and sometimes severe septicemia in human. In this study, a rapid detection method using latex agglutination has been developed for A. hydrophila. Polyclonal antibodies were raised against membrane and whole cells of three isolates from rainbow trout. Among these, latex particles coated with antibodies raised against whole cells of isolate No. 2 showed the best sensitivity. With latex particles coated with this antibody, we could detect $5{\times}10^4$ CFU of A. hydrophila in 5 min. The cross-reactivity with bacteria constituting the normal intestinal microflora and other pathogens for rainbow trout was insignificant. This latex agglutination assay method produced positive reaction with all clinical isolates of A. hydrophila which were identified by species-specific PCR for 16S rRNA in A. hydrophila.

• 정보저장시스템학회논문집
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• 제9권1호
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• pp.17-21
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• 2013

Optical coherence tomography (OCT) allows non-invasive, cross-sectional optical imaging of biological tissue with high spatial resolution and acquisition speed. In principle, it is analogous to ultrasound imaging, but uses near-infrared light instead of ultrasound, measuring the time-delay of back-scattered light from within biological tissue. Compared to ultrasound imaging, it exhibits superior spatial resolution (1~10 um) and high sensitivity. Therefore, OCT has been applied to a wide range of applications such as cellular imaging, ophthalmology and cardiology. Here, we describe a novel application of OCT technology in visualizing microneedles embedded in tissue that is developed to deliver drugs into the dermis without the injection mark in the human skin. Detailed three-dimensional structural images of microneedles and biological tissues were obtained. Examining structural modification of microneedles and tissues during insertion process would enable to evaluate performance of various types of microneedles in situ.

• Nuclear Engineering and Technology
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• 제49권6호
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• pp.1240-1249
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• 2017

An essential component of the neutron transport solver is the resonance self-shielding calculation used to determine equivalence cross sections. The neutron transport code, MPACT, is currently using the subgroup self-shielding method, in which the method of characteristics (MOC) is used to solve purely absorbing fixed-source problems. Recent efforts incorporating multigroup kernels to the MOC solvers in MPACT have reduced runtime by roughly $2{\times}$. Applying the same concepts for self-shielding and developing a novel lumped parameter approach to MOC, substantial improvements have also been made to the self-shielding computational efficiency without sacrificing any accuracy. These new multigroup and lumped parameter capabilities have been demonstrated on two test cases: (1) a single lattice with quarter symmetry known as VERA (Virtual Environment for Reactor Applications) Progression Problem 2a and (2) a two-dimensional quarter-core slice known as Problem 5a-2D. From these cases, self-shielding computational time was reduced by roughly $3-4{\times}$, with a corresponding 15-20% increase in overall memory burden. An azimuthal angle sensitivity study also shows that only half as many angles are needed, yielding an additional speedup of $2{\times}$. In total, the improvements yield roughly a $7-8{\times}$ speedup. Given these performance benefits, these approaches have been adopted as the default in MPACT.

• Nuclear Engineering and Technology
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• 제50권5호
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• pp.709-716
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• 2018

A criticality safety analysis was performed for the APR-1400 spent fuel pool region-II to ensure the safe storage of spent fuel, with credit taken for depletion and in-rack neutron absorbers (Metamic panels). PLUS7 fuel assembly was modeled using TRITON-NEWT of SCALE-6.1. The burnup-dependent cross-section library was generated under limiting core-operating conditions with 5%-w U-235 initial enrichment. MCNP5 was used to evaluate the neutron multiplication factor in an infinite array of rack cells with the axially nonuniformly burnt PLUS7 assemblies under normal, abnormal, and accident conditions; including all biases and uncertainties. The main purpose of this study is to investigate reactivity variations due to the critical depletion and reactor operation parameters. The approach, assumptions, and modeling methods were verified by analyzing the contents of the most important fissile and the associated reactivity effects. The Nuclear Regulatory Commission (NRC) guidance on k-eff being less than 1.0 for spent fuel pools filled with unborated water was the main criterion used in this study. It was found that assemblies with 49.0 GWd/MTU and 5.0 w/o U-235 initial enrichment loaded in Region-II satisfy this criterion. Moreover, it was found that the end effect resulted in a positive bias, thus ensuring its consideration.

• 펄프종이기술
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• 제32권5호
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• pp.14-25
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• 2000

In this investigation, a wavelet transform analysis was used to decompose beta-radiographic formation images into spectral and spatial components. Conventional formation analysis may use spectral analysis, based on Fourier transformation or variance vs. zone size, to describe the grammage distribution of features such as flocs, streaks and mean fiber orientation. However, these methods have limited utility for the analysis of statistically stationary data sets where variance is not uniform with position, e.g. paper machine CD profiles (especially those that contain streaks). A continuous wavelet transform was used to analyze formation data arrays obtained from radiographic imaging of handsheets and cross machine paper samples. The response of the analytical method to grammage, floc size distribution, mean fiber orientation an sensitivity to feature localization were assessed. From wavelet analysis, the change in scale of grammage variation as a function of position was used to demonstrate regular and isolated differences in the formed structure.

• 소성∙가공
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• 제23권3호
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• pp.178-183
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• 2014

Continuous casting is a process where molten metal is solidified into a semi-finished billet on a large scale with either a rectangular or round cross section for subsequent processing. The use of continuous casting provides an opportunity for producing material on a practical industrial scale with lower cost than conventional casting. In the current study, the material was fabricated by continuous casting and subsequent extrusion. Tensile tests were conducted on continuous cast ZK60A after extrusion over a range of strain rates at temperatures from 473K to 623K. The alloy exhibits a quasi-superplastic behavior with a maximum recorded elongation of ~250% at 523K when tested with an initial strain rate of $10^{-5}/s$. The experiments give a strain rate sensitivity exponent of 0.3~0.4 and an activation energy of 108 kJ/mol. From the current investigation, it was found that the high-temperature plastic flow of the ZK60A is controlled by a dislocation viscous glide mechanism.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2008년도 춘계학술대회 논문집
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• pp.205-208
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• 2008

Generally, there are several types in rear suspension. The rear suspension of subframe type consisting of side member and front/rear cross member is widely used in a medium car and full car. In the small car case, the beam of tubular type without independent suspension system is used to reduce manufacturing cost. The optimized rear suspension of subframe type using hydroforming method has been developed in this study. In designing suspension, the driving stability and durability performance should be considered as an important factor. The stability is related to dynamic frequency and durability is connected with stress analysis of structure. We focus on increasing the stiffness of suspension and decreasing the maximum stress relating to durability cycle life. For making use of the merits of hydroforming which is possible to make the bead, tube expansion, and feeding in desiring position, several optimization design techniques such as shape, size, and topology optimization are proposed. This optimization scheme based on the sensitivity can provide distinguished performance improvement in using hydroforming. Through commercial software based on the finite element, the superiority of this design method is demonstrated.

• 대한수의학회지
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• 제44권4호
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• pp.625-635
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• 2004

Trichnuris suis does not excrete eggs during larval stage as well as in particular adult stage, It is impossible to diagnose by use of fecal examination method in those periods. Therefore, serological diagnostic method can be very useful for those stages. In order to produce monoclonal antibody, specific somatic and secretory-excretory (SE) antigens of T. suis were identified and analyzed by SDS-PAGE and Western blot. Monoclonal antibody-producing hybridoma cells were cloned, which were made of popliteal lymph node of BALB/c mice immunized with a 45 kDa somatic antigen of T. suis. Five clones (1B9, 2C4, n2C5, 2D7 and 2D8) showing strong responses to T. suis antigens were selected and the isotype identified. All monoclonal antibodies were IgG1 isotype and the light chains were k chain. Established monoclonal antibodies reacted specifically to somatic and SE antigens of T. suis and did not cross-reacted to antigens of ascaris suum, trichuris vulpis, or Trichinella spiralis. The sensitivity of somatic and SE antigens against these monoclonal antibodies were significant (p<0.01) associated with those of positive and negative sera.

• Nuclear Engineering and Technology
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• 제53권9호
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• pp.2803-2815
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• 2021

This paper addresses the uncertainty quantification and sensitivity analysis of a depleted light-water fuel assembly of the Turkey Point-3 benchmark. The uncertainty of the fuel assembly decay heat and isotopic densities is quantified with respect to three different groups of diverse parameters: nuclear data, assembly design, and reactor core operation. The uncertainty propagation is conducted using a two-step analysis code system comprising the lattice code STREAM, nodal code RAST-K, and spent nuclear fuel module SNF through the random sampling of microscopic cross-sections, fuel rod sizes, number densities, reactor core total power, and temperature distributions. Overall, the statistical analysis of the calculated samples demonstrates that the decay heat uncertainty decreases with the cooling time. The nuclear data and assembly design parameters are proven to be the largest contributors to the decay heat uncertainty, whereas the reactor core power and inlet coolant temperature have a minor effect. The majority of the decay heat uncertainties are delivered by a small number of isotopes such as ²⁴¹Am, ¹³⁷Ba, ²⁴⁴Cm, ²³⁸Pu, and ⁹⁰Y.

• 산업경영시스템학회지
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• 제42권1호
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• pp.129-136
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• 2019

In this study, we proposed a model for forecasting power energy demand by investigating how outside temperature at a given time affected power consumption and. To this end, we analyzed the time series of power consumption in terms of the power spectrum and found the periodicities of one day and one week. With these periodicities, we investigated two time series of temperature and power consumption, and found, for a given hour, an approximate linear relation between temperature and power consumption. We adopted an exponential smoothing model to examine the effect of the linearity in forecasting the power demand. In particular, we adjusted the exponential smoothing model by using the variation of power consumption due to temperature change. In this way, the proposed model became a mixture of a time series model and a regression model. We demonstrated that the adjusted model outperformed the exponential smoothing model alone in terms of the mean relative percentage error and the root mean square error in the range of 3%~8% and 4kWh~27kWh, respectively. The results of this study can be used to the energy management system in terms of the effective control of the cross usage of the electric energy together with the outside temperature.